UA70410C2 - Pharmaceutical formulation comprising hmg-coa redupharmaceutical formulation comprising hmg-coa reductase inhibitor (variants), method for preparing sctase inhibitor (variants), method for preparing stabilized hmg-coa reductase inhibitor tabilized hmg-coa reductase inhibitor - Google Patents
Pharmaceutical formulation comprising hmg-coa redupharmaceutical formulation comprising hmg-coa reductase inhibitor (variants), method for preparing sctase inhibitor (variants), method for preparing stabilized hmg-coa reductase inhibitor tabilized hmg-coa reductase inhibitor Download PDFInfo
- Publication number
- UA70410C2 UA70410C2 UA2002119464A UA2002119464A UA70410C2 UA 70410 C2 UA70410 C2 UA 70410C2 UA 2002119464 A UA2002119464 A UA 2002119464A UA 2002119464 A UA2002119464 A UA 2002119464A UA 70410 C2 UA70410 C2 UA 70410C2
- Authority
- UA
- Ukraine
- Prior art keywords
- coa reductase
- reductase inhibitor
- specified
- substance
- nmo
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims abstract description 113
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 7
- 238000000034 method Methods 0.000 title claims description 17
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 title abstract description 5
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 title abstract description 5
- 239000003112 inhibitor Substances 0.000 title description 14
- 238000009472 formulation Methods 0.000 title 1
- 239000000126 substance Substances 0.000 claims abstract description 45
- 239000013543 active substance Substances 0.000 claims abstract description 40
- 239000006172 buffering agent Substances 0.000 claims abstract description 8
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical group CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims description 81
- 229940123934 Reductase inhibitor Drugs 0.000 claims description 43
- 230000003113 alkalizing effect Effects 0.000 claims description 38
- 239000000872 buffer Substances 0.000 claims description 32
- TUZYXOIXSAXUGO-UHFFFAOYSA-N Pravastatin Natural products C1=CC(C)C(CCC(O)CC(O)CC(O)=O)C2C(OC(=O)C(C)CC)CC(O)C=C21 TUZYXOIXSAXUGO-UHFFFAOYSA-N 0.000 claims description 26
- 229960002965 pravastatin Drugs 0.000 claims description 26
- TUZYXOIXSAXUGO-PZAWKZKUSA-N pravastatin Chemical compound C1=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@H]2[C@@H](OC(=O)[C@@H](C)CC)C[C@H](O)C=C21 TUZYXOIXSAXUGO-PZAWKZKUSA-N 0.000 claims description 26
- 229960001495 pravastatin sodium Drugs 0.000 claims description 24
- 150000003839 salts Chemical class 0.000 claims description 24
- VWBQYTRBTXKKOG-IYNICTALSA-M pravastatin sodium Chemical compound [Na+].C1=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC([O-])=O)[C@H]2[C@@H](OC(=O)[C@@H](C)CC)C[C@H](O)C=C21 VWBQYTRBTXKKOG-IYNICTALSA-M 0.000 claims description 23
- 239000003795 chemical substances by application Substances 0.000 claims description 15
- XUKUURHRXDUEBC-KAYWLYCHSA-N Atorvastatin Chemical compound C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CC[C@@H](O)C[C@@H](O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-KAYWLYCHSA-N 0.000 claims description 11
- XUKUURHRXDUEBC-UHFFFAOYSA-N Atorvastatin Natural products C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CCC(O)CC(O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-UHFFFAOYSA-N 0.000 claims description 11
- 229960005370 atorvastatin Drugs 0.000 claims description 11
- 238000000975 co-precipitation Methods 0.000 claims description 10
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- ZGGHKIMDNBDHJB-NRFPMOEYSA-M (3R,5S)-fluvastatin sodium Chemical compound [Na+].C12=CC=CC=C2N(C(C)C)C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C1C1=CC=C(F)C=C1 ZGGHKIMDNBDHJB-NRFPMOEYSA-M 0.000 claims description 7
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 7
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- SEERZIQQUAZTOL-ANMDKAQQSA-N cerivastatin Chemical compound COCC1=C(C(C)C)N=C(C(C)C)C(\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)=C1C1=CC=C(F)C=C1 SEERZIQQUAZTOL-ANMDKAQQSA-N 0.000 claims description 7
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- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 4
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Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/591,322 US6531507B1 (en) | 2000-06-09 | 2000-06-09 | Stabilized pharmaceutically effective composition and pharmaceutical formulation comprising the same |
PCT/IB2000/000773 WO2001093860A1 (en) | 2000-06-09 | 2000-06-09 | Stabilized pharmaceutically effective composition and pharmaceutical formulation comprising the same |
Publications (1)
Publication Number | Publication Date |
---|---|
UA70410C2 true UA70410C2 (en) | 2004-10-15 |
Family
ID=26318615
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UA2002119464A UA70410C2 (en) | 2000-06-09 | 2000-09-06 | Pharmaceutical formulation comprising hmg-coa redupharmaceutical formulation comprising hmg-coa reductase inhibitor (variants), method for preparing sctase inhibitor (variants), method for preparing stabilized hmg-coa reductase inhibitor tabilized hmg-coa reductase inhibitor |
Country Status (19)
Country | Link |
---|---|
US (1) | US6531507B1 (ru) |
EP (1) | EP1292293B1 (ru) |
JP (1) | JP2004501121A (ru) |
AT (1) | ATE260101T1 (ru) |
AU (2) | AU4943400A (ru) |
BG (1) | BG107360A (ru) |
CA (1) | CA2412326A1 (ru) |
CZ (1) | CZ20023826A3 (ru) |
DE (1) | DE60008608T2 (ru) |
ES (1) | ES2215050T3 (ru) |
HR (1) | HRP20020950A2 (ru) |
HU (1) | HUP0301325A3 (ru) |
NO (1) | NO20025784L (ru) |
PL (1) | PL362764A1 (ru) |
RU (1) | RU2246943C2 (ru) |
SI (1) | SI1292293T1 (ru) |
SK (1) | SK16982002A3 (ru) |
UA (1) | UA70410C2 (ru) |
WO (1) | WO2001093860A1 (ru) |
Families Citing this family (39)
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US20110196039A9 (en) * | 1994-10-05 | 2011-08-11 | Kaesemeyer Wayne H | Controlled release arginine formulations |
SI20109A (sl) * | 1998-12-16 | 2000-06-30 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Stabilna farmacevtska formulacija |
US7411075B1 (en) * | 2000-11-16 | 2008-08-12 | Teva Pharmaceutical Industries Ltd. | Polymorphic form of atorvastatin calcium |
USRE44578E1 (en) | 2000-04-10 | 2013-11-05 | Teva Pharmaceutical Industries, Ltd. | Stable pharmaceutical compositions containing 7-substituted-3,5-dihydroxyheptanoic acids or 7-substituted-3,5-dihydroxyheptenoic acids |
US6806290B2 (en) * | 2000-06-09 | 2004-10-19 | Lek Pharmaceuticals D.D. | Stabilized pharmaceutically effective composition and pharmaceutical formulation comprising the same |
EP1345903A1 (en) * | 2000-12-21 | 2003-09-24 | Ciba SC Holding AG | Crystalline forms of cerivastatin sodium |
SI20848A (sl) * | 2001-03-14 | 2002-10-31 | Lek, Tovarna Farmacevtskih In Kemijskih Izdelkov, D.D. | Farmacevtska formulacija, ki vsebuje atorvastatin kalcij |
GB0111077D0 (en) * | 2001-05-04 | 2001-06-27 | Biochemie Gmbh | Organic compounds |
JP2005500307A (ja) * | 2001-06-21 | 2005-01-06 | アンドルックス ファーマスーティカルズ インコーポレーテッド | プラバスタチンを含む安定な徐放性薬剤組成物 |
US20040180087A1 (en) * | 2001-06-21 | 2004-09-16 | Boyong Li | Stable controlled release pharmaceutical compositions containing pravastatin |
WO2003013607A1 (en) * | 2001-08-07 | 2003-02-20 | Galephar M/F | ORAL PHARMACEUTICAL COMPOSITION CONTAINING A COMBINATION OF FENOFIBRATE AND A HMG-CoA REDUCTASE INHIBITOR |
AU2002353659A1 (en) * | 2001-12-18 | 2003-07-15 | Synthon B.V. | Simvastatin dosage forms |
CA2385529A1 (en) * | 2002-05-21 | 2003-11-21 | Bernard Charles Sherman | Stable dosage forms comprising atorvastatin calcium |
JP2005532362A (ja) * | 2002-06-13 | 2005-10-27 | ノバルティス アクチエンゲゼルシャフト | インドール誘導スタチンのカルシウム塩 |
US20060029668A1 (en) * | 2002-10-24 | 2006-02-09 | Ron Eyal S | Sustained release L-arginine formulations and methods of manufacture and use |
KR20050083827A (ko) * | 2002-10-24 | 2005-08-26 | 이노스 파마슈티칼스, 인코포레이티드 | 서방성 l-아르기닌 포뮬레이션 및 이의 제조방법 및 용도 |
US20080145424A1 (en) * | 2002-10-24 | 2008-06-19 | Enos Phramaceuticals, Inc. | Sustained release L-arginine formulations and methods of manufacture and use |
BR0317593A (pt) * | 2002-12-20 | 2005-11-22 | Pfizer Prod Inc | Formas de dosagem compreendendo um inibidor de cetp e um inibidor de hmg-coa reductase |
US7655692B2 (en) * | 2003-06-12 | 2010-02-02 | Pfizer Inc. | Process for forming amorphous atorvastatin |
JP2007521324A (ja) * | 2003-09-29 | 2007-08-02 | エノス ファーマシューティカルズ, インク. | 徐放性l−アルギニン調合物並びにその製造法及び使用法 |
US8163797B2 (en) * | 2003-12-31 | 2012-04-24 | Actavis Elizabeth Llc | Method of treating with stable pravastatin formulation |
EP1737449A1 (en) * | 2004-03-01 | 2007-01-03 | LEK Pharmaceuticals D.D. | Pharmaceutical composition |
CN1942439B (zh) | 2004-03-17 | 2011-12-21 | 兰贝克赛实验室有限公司 | 无定形形式的阿托伐他汀钙的制备方法 |
US7491263B2 (en) * | 2004-04-05 | 2009-02-17 | Technology Innovation, Llc | Storage assembly |
US20090042979A1 (en) * | 2004-08-06 | 2009-02-12 | Transform Pharmaceuticals Inc. | Novel Statin Pharmaceutical Compositions and Related Methods of Treatment |
CA2573316A1 (en) * | 2004-08-06 | 2006-02-16 | Transform Pharmaceuticals, Inc. | Novel fenofibrate formulations and related methods of treatment |
EP1786414A4 (en) * | 2004-08-06 | 2008-04-09 | Transform Pharmaceuticals Inc | NEW PHARMACEUTICAL STATIN COMPOSITIONS AND RELEVANT TREATMENT PROCEDURES |
AU2005305460B2 (en) | 2004-11-22 | 2011-04-21 | Dexcel Pharma Technologies Ltd. | Stable atorvastatin formulations |
EP1846037A4 (en) * | 2005-01-24 | 2008-03-12 | Palmetto Pharmaceuticals Llc | METHODS OF TREATING VARIOUS CONDITIONS BY ADMINISTERING L-ARGININE WITH PROLONGED RELEASE |
WO2006123358A2 (en) * | 2005-02-22 | 2006-11-23 | Sun Pharmaceutical Industries Limited | Stabilized atorvastatin-containing formulation |
US20060229277A1 (en) * | 2005-04-08 | 2006-10-12 | Orbus Pharma, Inc. | Stabilized pharmaceutical compositions comprising an HMG-CoA reductase inhibitor |
JP4813841B2 (ja) * | 2005-07-25 | 2011-11-09 | キユーピー株式会社 | プラバスタチンナトリウムの製造方法 |
WO2007016757A1 (en) * | 2005-08-05 | 2007-02-15 | Orbus Pharma Inc. | Stabilized extended release pharmeceutical compositions comprising an hmg-coa reductase inhibitor |
WO2007020079A2 (en) * | 2005-08-17 | 2007-02-22 | Synthon B.V. | Orally disintegratable simvastatin tablets |
US7772273B2 (en) * | 2006-02-10 | 2010-08-10 | Lifecycle Pharma A/S | Stabilized atorvastatin |
MX2008010879A (es) * | 2006-02-24 | 2008-10-27 | Teva Pharma | Composiciones farmaceuticas de sodio de fluvastatina. |
DE102007052071A1 (de) | 2007-10-30 | 2009-05-07 | Stada Arzneimittel Ag | Stabilisiertes Atorvastatin |
IN2014CN04119A (ru) | 2011-11-15 | 2015-07-10 | Reddys Lab Ltd Dr | |
KR101466617B1 (ko) * | 2011-11-17 | 2014-11-28 | 한미약품 주식회사 | 오메가-3 지방산 및 HMG-CoA 환원효소 억제제를 포함하는 안정성이 증가된 경구용 복합 제제 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
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ES8105781A1 (es) * | 1979-07-27 | 1981-06-16 | Sankyo Co | Un procedimiento para la preparacion de sales y esteres, de monacolina k utiles como agentes antitlipercolesteremicos. |
US5030447A (en) | 1988-03-31 | 1991-07-09 | E. R. Squibb & Sons, Inc. | Pharmaceutical compositions having good stability |
HU9203780D0 (en) | 1991-12-12 | 1993-03-29 | Sandoz Ag | Stabilized pharmaceutical products of hmg-coa reductase inhibitor and method for producing them |
DE69324504T2 (de) * | 1993-01-19 | 1999-08-26 | Warner Lambert Co | Stabilisierte, oral anzuwendende zusammensetzung enthaltend die verbindung ci-981 und verfahren |
NO318765B1 (no) | 1995-07-03 | 2005-05-02 | Sankyo Co | Anvendelse av en HMG-CoA reduktaseinhibitor og en insulinsensibilisator til fremstilling av et medikament for forebyggelse eller behandling av arteriosklerose eller xantom, samt pakket farmasoytisk preparat som omfatter de to midlene i separate porsjoner. |
DE69616808T2 (de) * | 1995-07-17 | 2002-05-29 | Warner Lambert Co | Kristallines (r-(r*,r*))-2-(4-fluorphenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-1h-pyrrol-1-heptancarbonsäure hemi calcium salz (atorvastatin) |
PT814782E (pt) | 1995-12-22 | 2003-04-30 | Nissan Chemical Ind Ltd | Composicao farmaceutica estabilizada com um agente basico |
SI20070A (sl) | 1998-09-18 | 2000-04-30 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Nove soli inhibitorjev HMG-CoA reduktaze |
SI20109A (sl) * | 1998-12-16 | 2000-06-30 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Stabilna farmacevtska formulacija |
-
2000
- 2000-06-09 SI SI200030324T patent/SI1292293T1/xx unknown
- 2000-06-09 SK SK1698-2002A patent/SK16982002A3/sk not_active Application Discontinuation
- 2000-06-09 RU RU2002134764/15A patent/RU2246943C2/ru not_active IP Right Cessation
- 2000-06-09 DE DE60008608T patent/DE60008608T2/de not_active Expired - Lifetime
- 2000-06-09 AT AT00931486T patent/ATE260101T1/de active
- 2000-06-09 CZ CZ20023826A patent/CZ20023826A3/cs unknown
- 2000-06-09 CA CA002412326A patent/CA2412326A1/en not_active Abandoned
- 2000-06-09 WO PCT/IB2000/000773 patent/WO2001093860A1/en active IP Right Grant
- 2000-06-09 AU AU4943400A patent/AU4943400A/xx active Pending
- 2000-06-09 JP JP2002501433A patent/JP2004501121A/ja active Pending
- 2000-06-09 EP EP00931486A patent/EP1292293B1/en not_active Revoked
- 2000-06-09 ES ES00931486T patent/ES2215050T3/es not_active Expired - Lifetime
- 2000-06-09 PL PL00362764A patent/PL362764A1/xx not_active Application Discontinuation
- 2000-06-09 AU AU2000249434A patent/AU2000249434B2/en not_active Ceased
- 2000-06-09 US US09/591,322 patent/US6531507B1/en not_active Expired - Fee Related
- 2000-06-09 HU HU0301325A patent/HUP0301325A3/hu unknown
- 2000-09-06 UA UA2002119464A patent/UA70410C2/uk unknown
-
2002
- 2002-12-02 NO NO20025784A patent/NO20025784L/no not_active Application Discontinuation
- 2002-12-02 HR HRP20020950 patent/HRP20020950A2/hr not_active Application Discontinuation
- 2002-12-06 BG BG107360A patent/BG107360A/bg unknown
Also Published As
Publication number | Publication date |
---|---|
WO2001093860A1 (en) | 2001-12-13 |
HRP20020950A2 (en) | 2004-12-31 |
SK16982002A3 (sk) | 2003-04-01 |
RU2246943C2 (ru) | 2005-02-27 |
CA2412326A1 (en) | 2001-12-13 |
NO20025784D0 (no) | 2002-12-02 |
AU4943400A (en) | 2001-12-17 |
HUP0301325A2 (hu) | 2003-11-28 |
DE60008608T2 (de) | 2004-12-30 |
CZ20023826A3 (cs) | 2003-04-16 |
BG107360A (bg) | 2003-11-28 |
EP1292293B1 (en) | 2004-02-25 |
HUP0301325A3 (en) | 2004-03-01 |
US6531507B1 (en) | 2003-03-11 |
DE60008608D1 (de) | 2004-04-01 |
JP2004501121A (ja) | 2004-01-15 |
NO20025784L (no) | 2002-12-02 |
SI1292293T1 (en) | 2004-06-30 |
AU2000249434B2 (en) | 2006-02-02 |
EP1292293A1 (en) | 2003-03-19 |
ATE260101T1 (de) | 2004-03-15 |
PL362764A1 (en) | 2004-11-02 |
ES2215050T3 (es) | 2004-10-01 |
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