TWI319764B - Mercaptoacetylamide derivatives, a process for their preparation and their use - Google Patents

Mercaptoacetylamide derivatives, a process for their preparation and their use

Info

Publication number: TWI319764B
Authority: TW; Taiwan
Prior art keywords: preparation; mercaptoacetylamide derivatives; mercaptoacetylamide; derivatives
Prior art date: 2001-04-12

Application number

TW091107133A

Other languages

English (en)

Inventor

A Flynn Gary

Mehdi Shufaath

Franklin Clearman Jack

Dietrich Manfred

Jablonka Bernd

Kleemann Heinz-Wernere

Linz Wolfgang

Seiz Werner

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-04-12

Filing date

2002-04-10

Publication date

2010-01-21

2002-04-10 Application filed filed Critical

2010-01-21 Application granted granted Critical

2010-01-21 Publication of TWI319764B publication Critical patent/TWI319764B/zh

Links

GYXHHICIFZSKKZ-UHFFFAOYSA-N 2-sulfanylacetamide Chemical class NC(=O)CS GYXHHICIFZSKKZ-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

TW091107133A 2001-04-12 2002-04-10 Mercaptoacetylamide derivatives, a process for their preparation and their use TWI319764B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US28330501P	2001-04-12	2001-04-12
GBGB0119305.1A GB0119305D0 (en)	2001-04-12	2001-08-08	Mercaptoacetylamide derivatives,a process for their preparation and their use

Publications (1)

Publication Number	Publication Date
TWI319764B true TWI319764B (en)	2010-01-21

Family

ID=23085405

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TW091107133A TWI319764B (en)	2001-04-12	2002-04-10	Mercaptoacetylamide derivatives, a process for their preparation and their use

Country Status (17)

Country	Link
US (1)	US6602866B2 (zh)
KR (1)	KR100910929B1 (zh)
AR (1)	AR034307A1 (zh)
CR (1)	CR7074A (zh)
DK (1)	DK1381605T3 (zh)
EC (1)	ECSP034782A (zh)
GB (1)	GB0119305D0 (zh)
GT (1)	GT200200069A (zh)
IL (1)	IL158289A (zh)
MY (1)	MY128226A (zh)
PE (1)	PE20021079A1 (zh)
RS (1)	RS50919B (zh)
TN (1)	TNSN03083A1 (zh)
TW (1)	TWI319764B (zh)
UA (1)	UA75647C2 (zh)
UY (1)	UY27255A1 (zh)
ZA (1)	ZA200307096B (zh)

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JP5885832B2 (ja)	2011-05-31	2016-03-16	セラヴァンスバイオファーマアール＆ディーアイピー，エルエルシー	ネプリライシン阻害剤
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ES2609810T3 (es)	2012-05-31	2017-04-24	Theravance Biopharma R&D Ip, Llc	Inhibidores de neprilisina donadores de óxido nítrico
US8871792B2 (en)	2012-06-08	2014-10-28	Theravance Biopharma R&D Ip, Llc	Neprilysin inhibitors
WO2013184934A1 (en)	2012-06-08	2013-12-12	Theravance, Inc.	Neprilysin inhibitors
KR102104954B1 (ko)	2012-08-08	2020-04-27	세라밴스 바이오파마 알앤디 아이피, 엘엘씨	네프릴리신 억제제
US8901169B2 (en)	2013-03-05	2014-12-02	Theravance Biopharma R&D Ip, Llc	Neprilysin inhibitors
EP3099678B1 (en)	2014-01-30	2018-12-12	Theravance Biopharma R&D IP, LLC	Neprilysin inhibitors
MX2016009759A (es)	2014-01-30	2016-11-17	Theravance Biopharma R&D Ip Llc	Inhibidores de neprilisina.
US9433598B2 (en)	2015-02-11	2016-09-06	Theravance Biopharma R&D Ip, Llc	(2S,4R)-5-(5′-chloro-2′-fluorobiphenyl-4-yl)-4-(ethoxyoxalylamino)-2-hydroxymethyl-2-methylpentanoic acid
SG11201706662YA (en)	2015-02-19	2017-09-28	Theravance Biopharma R&D Ip Llc	(2r,4r)-5-(5'-chloro-2'-fluorobiphenyl-4-yl)-2-hydroxy-4-[(5-methyloxazole-2-carbonyl)amino]pentanoic acid
TWI731943B (zh)	2016-03-08	2021-07-01	美商施萬生物製藥研發Ｉｐ有限責任公司	結晶型（2s，4r）－5－（5’－氯－2’－氟－［1，1’－聯苯］－4－基）－2－（乙氧基甲基）－4－（3－羥基異㗁唑－5－甲醯胺基）－2－甲基戊酸及其用途

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WO1993023403A1 (en)	1992-05-15	1993-11-25	Merrell Dow Pharmaceuticals Inc.	NOVEL MERCAPTOACETYLAMIDO PYRIDAZO[1,2]PYRIDAZINE, PYRAZOLO[1,2]PYRIDAZINE, PYRIDAZO[1,2-a][1,2]DIAZEPINE AND PYRAZOLO[1,2-a][1,2]DIAZEPINE DERIVATIVES USEFUL AS INHIBITORS OF ENKEPHALINASE AND ACE
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2001
- 2001-08-08 GB GBGB0119305.1A patent/GB0119305D0/en not_active Ceased
2002
- 2002-03-04 UA UA20031110184A patent/UA75647C2/uk unknown
- 2002-04-03 RS YUP-787/03A patent/RS50919B/sr unknown
- 2002-04-03 KR KR1020037013181A patent/KR100910929B1/ko not_active IP Right Cessation
- 2002-04-03 DK DK02732549T patent/DK1381605T3/da active
- 2002-04-08 US US10/118,179 patent/US6602866B2/en not_active Expired - Lifetime
- 2002-04-10 TW TW091107133A patent/TWI319764B/zh not_active IP Right Cessation
- 2002-04-10 AR ARP020101321A patent/AR034307A1/es active IP Right Grant
- 2002-04-10 UY UY27255A patent/UY27255A1/es not_active Application Discontinuation
- 2002-04-10 MY MYPI20021326A patent/MY128226A/en unknown
- 2002-04-10 GT GT200200069A patent/GT200200069A/es unknown
- 2002-04-10 PE PE2002000294A patent/PE20021079A1/es not_active Application Discontinuation
2003
- 2003-07-08 TN TNPCT/EP2002/003668A patent/TNSN03083A1/en unknown
- 2003-09-11 ZA ZA200307096A patent/ZA200307096B/en unknown
- 2003-09-12 CR CR7074A patent/CR7074A/es not_active Application Discontinuation
- 2003-09-26 EC EC2003004782A patent/ECSP034782A/es unknown
- 2003-10-07 IL IL158289A patent/IL158289A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
UY27255A1 (es)	2002-07-31
PE20021079A1 (es)	2003-02-19
AR034307A1 (es)	2004-02-18
RS50919B (sr)	2010-08-31
CR7074A (es)	2007-12-04
YU78703A (sh)	2006-05-25
UA75647C2 (en)	2006-05-15
MY128226A (en)	2007-01-31
ECSP034782A (es)	2003-12-01
GB0119305D0 (en)	2001-10-03
US20020193589A1 (en)	2002-12-19
DK1381605T3 (da)	2005-05-09
US6602866B2 (en)	2003-08-05
ZA200307096B (en)	2004-09-06
KR100910929B1 (ko)	2009-08-06
GT200200069A (es)	2002-12-17
TNSN03083A1 (en)	2005-12-23
IL158289A (en)	2010-11-30
KR20040008153A (ko)	2004-01-28

Legal Events

Date	Code	Title	Description
2016-10-21	MM4A	Annulment or lapse of patent due to non-payment of fees

Publication	Publication Date	Title
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