TR200000312T2 - Biyolojik açıdan aktif makro moleküller içeren sulu aerosol karışımları. - Google Patents

Biyolojik açıdan aktif makro moleküller içeren sulu aerosol karışımları.

Info

Publication number
TR200000312T2
TR200000312T2 TR2000/00312T TR200000312T TR200000312T2 TR 200000312 T2 TR200000312 T2 TR 200000312T2 TR 2000/00312 T TR2000/00312 T TR 2000/00312T TR 200000312 T TR200000312 T TR 200000312T TR 200000312 T2 TR200000312 T2 TR 200000312T2
Authority
TR
Turkey
Prior art keywords
mixtures containing
biologically active
aqueous aerosol
aerosol mixtures
containing biologically
Prior art date
Application number
TR2000/00312T
Other languages
English (en)
Inventor
Lamche Herbert
John Montague Meade Cristopher
Zierenberg Bernd
Christan Reimholz Ralph
Original Assignee
Boehringer Ingelheim Pharma Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma Kg filed Critical Boehringer Ingelheim Pharma Kg
Publication of TR200000312T2 publication Critical patent/TR200000312T2/tr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44Oxidoreductases (1)
    • A61K38/446Superoxide dismutase (1.15)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Otolaryngology (AREA)
  • Diabetes (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Eldeki bulus, solunabilir aerosollarin itici gazsiz olarak üretilmesi amaciyla biyolojik aktiviteli makro molekülleri içeren sulu aerosol karisimlarini kapsamaktadir.
TR2000/00312T 1997-08-04 1998-07-31 Biyolojik açıdan aktif makro moleküller içeren sulu aerosol karışımları. TR200000312T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19733651A DE19733651A1 (de) 1997-08-04 1997-08-04 Wässrige Aerosolzubereitungen enthaltend biologisch aktive Markomoleküle und Verfahren zur Erzeugung entsprechender Aerosole

Publications (1)

Publication Number Publication Date
TR200000312T2 true TR200000312T2 (tr) 2000-07-21

Family

ID=7837935

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/00312T TR200000312T2 (tr) 1997-08-04 1998-07-31 Biyolojik açıdan aktif makro moleküller içeren sulu aerosol karışımları.

Country Status (36)

Country Link
US (1) US20030064032A1 (tr)
EP (2) EP1003478B1 (tr)
JP (1) JP2001513492A (tr)
KR (1) KR20010022636A (tr)
CN (1) CN1177581C (tr)
AR (1) AR016581A1 (tr)
AT (1) ATE301987T1 (tr)
AU (1) AU753673B2 (tr)
BG (1) BG64966B1 (tr)
BR (1) BR9811827A (tr)
CA (1) CA2297174A1 (tr)
CO (1) CO4960637A1 (tr)
DE (2) DE19733651A1 (tr)
DK (1) DK1003478T3 (tr)
EA (1) EA002255B1 (tr)
EE (1) EE05053B1 (tr)
ES (1) ES2248915T3 (tr)
HK (1) HK1027749A1 (tr)
HR (1) HRP980425B1 (tr)
HU (1) HUP0003805A3 (tr)
ID (1) ID24200A (tr)
IL (2) IL134115A0 (tr)
MY (1) MY132852A (tr)
NO (1) NO20000553L (tr)
NZ (1) NZ503160A (tr)
PL (1) PL338421A1 (tr)
PT (1) PT1003478E (tr)
RS (1) RS49705B (tr)
SI (1) SI1003478T1 (tr)
SK (1) SK285637B6 (tr)
TR (1) TR200000312T2 (tr)
TW (1) TWI222887B (tr)
UA (1) UA73076C2 (tr)
UY (1) UY25122A1 (tr)
WO (1) WO1999007340A1 (tr)
ZA (1) ZA986931B (tr)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030215396A1 (en) 1999-09-15 2003-11-20 Boehringer Ingelheim Pharma Kg Method for the production of propellant gas-free aerosols from aqueous medicament preparations
US7963955B2 (en) 1998-02-27 2011-06-21 Boehringer Ingelheim International Gmbh Container for a medicinal liquid
SE9801495D0 (sv) * 1998-04-28 1998-04-28 Astra Ab Protein formulationa
US20060171899A1 (en) * 1998-12-10 2006-08-03 Akwete Adjei Water-stabilized aerosol formulation system and method of making
RU2140285C1 (ru) * 1999-01-25 1999-10-27 Гапонюк Петр Яковлевич Противовирусное средство - капли в нос "гриппферон"
US6350432B1 (en) * 1999-03-19 2002-02-26 Generex Pharmaceuticals Incorporated Pressurized container having an aerosolized pharmaceutical composition
NZ519403A (en) * 2001-06-21 2005-03-24 Pfizer Prod Inc Use of insulin in a medicament to reduce weight gain in a diabetic patient who is using exogenous insulin to control blood sugar levels
DE102004001451A1 (de) 2004-01-08 2005-08-11 Boehringer Ingelheim International Gmbh Vorrichtung zum Haltern eines fluidischen Bauteiles
DE102004011381A1 (de) 2004-03-05 2005-09-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Impaktionsdüse für treibgasbetriebene Dosieraerosole
US7611709B2 (en) 2004-05-10 2009-11-03 Boehringer Ingelheim Pharma Gmbh And Co. Kg 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives
US7727962B2 (en) 2004-05-10 2010-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder comprising new compositions of oligosaccharides and methods for their preparation
US7723306B2 (en) 2004-05-10 2010-05-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation
DE102005024439A1 (de) 2005-05-24 2006-12-07 Boehringer Ingelheim International Gmbh Zerstäuber
DE102005029746B4 (de) 2005-06-24 2017-10-26 Boehringer Ingelheim International Gmbh Zerstäuber
EP1909873B1 (en) * 2005-06-27 2011-09-21 World Health Organization Vaccine nebulisers
CN101247897B (zh) 2005-08-24 2013-06-12 贝林格尔·英格海姆国际有限公司 雾化器
DE102006009637A1 (de) 2005-10-28 2007-05-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator mit Mundstück mit mikrobiologischer Schutzfunktion
AU2005338631B2 (en) * 2005-11-30 2011-12-01 Generex Pharmaceuticals Inc. Orally absorbed pharmaceutical formulation and method of administration
EP1792660A1 (en) 2005-12-02 2007-06-06 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
DE102006014433A1 (de) 2006-03-27 2007-10-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Dosieraerosole für die Verabreichung von pharmazeutischen Zubereitungen
DE102006016903A1 (de) 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
DE102006016901A1 (de) 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Mundstück für einen Inhalator
US7841338B2 (en) 2006-04-13 2010-11-30 Boehringer Ingelheim International Gmbh Dispensing device
EP1844809A1 (de) 2006-04-13 2007-10-17 Boehringer Ingelheim Pharma GmbH & Co. KG Medikamentenmagazin für einen Inhalator, sowie Mehrdosispulverinhalator
EP1844808A1 (de) 2006-04-13 2007-10-17 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG Medikamenten-Ausgabevorrichtung
EP1844807A1 (de) 2006-04-13 2007-10-17 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG Medikamentenmagazin, sowie Vorrichtung und Verfahren zum Öffnen desselben; Mehrdosispulverinhalator
DE102006022002A1 (de) 2006-05-10 2007-11-15 Boehringer Ingelheim International Gmbh Zerstäuber und Verfahren zur Zerstäubung von Fluid
DE102006043637A1 (de) 2006-05-18 2007-11-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Zerstäuber
US8061350B2 (en) 2006-06-02 2011-11-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Process and device for dosing pharmaceutical agents
DE102007020578A1 (de) 2007-05-02 2008-11-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Wässrige Aerosolzubereitungen enthaltend therapeutisch wirksame Mikroorganismen oder Teile von Mikroorganismen und Verfahren zur Erzeugung entsprechender Aerosole
DE102007023012A1 (de) 2007-05-15 2008-11-20 Boehringer Ingelheim Pharma Gmbh & Co. Kg Zerstäuber und Filter
EP2676694B1 (en) 2007-06-15 2017-04-26 Boehringer Ingelheim International GmbH Inhaler
EP2011536A1 (en) 2007-07-06 2009-01-07 Boehringer Ingelheim Pharma GmbH & Co. KG Inhaler
CN100593424C (zh) * 2007-07-18 2010-03-10 北京万生药业有限责任公司 一种氧气湿化及输送装置
DE102007033860A1 (de) 2007-07-20 2009-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Prüfvorrichtung
DE102007033861A1 (de) 2007-07-20 2009-07-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator
DE102007036411A1 (de) 2007-07-20 2009-02-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator
DE102007034156A1 (de) 2007-07-21 2009-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Vorrichtung und Verfahren zur Bestimmung des Feuchtegehalts eines Verpackungsmaterials
DE102007036413A1 (de) 2007-08-02 2009-02-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Vorrichtung und Verfahren zur Bestimmung des Feuchtegehalts eines Verpackungsmaterials
DE102007052871A1 (de) 2007-11-02 2009-05-07 Boehringer Ingelheim Pharma Gmbh & Co. Kg Kapsel zur Aufnahme von pharmazeutischen Wirkstoffformulierungen
DE102007058112A1 (de) 2007-12-03 2009-06-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator mit Wirkstofftablette
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
AU2009226643A1 (en) 2008-03-17 2009-09-24 Boehringer Ingelheim International Gmbh Reservoir and nebulizer
EP2135632A1 (de) 2008-06-20 2009-12-23 Boehringer Ingelheim International Gmbh Inhalator
EP2198972A1 (de) 2008-12-18 2010-06-23 Boehringer Ingelheim International GmbH Reservoir und Zerstäuber
WO2010076012A1 (de) 2009-01-02 2010-07-08 Boehringer Ingelheim International Gmbh Bauteil und inhalator sowie verfahren zur herstellung eines bauteils
JP5620466B2 (ja) 2009-03-17 2014-11-05 ベーリンガーインゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング リザーバ及びアトマイザ
EP2408500B1 (en) 2009-03-17 2015-04-29 Boehringer Ingelheim International GmbH Dispensing device, and storage device for dispensing a formulation
JP5670421B2 (ja) 2009-03-31 2015-02-18 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング コンポーネント表面のコーティング方法
WO2010124795A1 (de) 2009-04-28 2010-11-04 Boehringer Ingelheim International Gmbh Inhalationsvorrichtung
EP2432531B1 (de) 2009-05-18 2019-03-06 Boehringer Ingelheim International GmbH Adapter, inhalationseinrichtung und zerstäuber
MX2011013077A (es) 2009-06-25 2012-01-20 Boehringer Ingelheim Vetmed Inhalador.
US8746244B2 (en) 2009-10-02 2014-06-10 Boehringer Ingelheim International Gmbh Powder inhaler
EP2504051B1 (en) 2009-11-25 2019-09-04 Boehringer Ingelheim International GmbH Nebulizer
JP5715640B2 (ja) 2009-11-25 2015-05-13 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
US9943654B2 (en) 2010-06-24 2018-04-17 Boehringer Ingelheim International Gmbh Nebulizer
EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
CN103386125A (zh) * 2012-05-08 2013-11-13 刘江秋 肾综合征出血热鼻黏膜免疫气溶胶疫苗的研制
EP3030298B1 (en) 2013-08-09 2017-10-11 Boehringer Ingelheim International GmbH Nebulizer
ES2836977T3 (es) 2013-08-09 2021-06-28 Boehringer Ingelheim Int Nebulizador
CN103575718A (zh) * 2013-11-21 2014-02-12 中国人民解放军63975部队 用量子点荧光传感体系测定蛋白喷剂雾化效果的方法
CN106255554B (zh) 2014-05-07 2021-05-04 勃林格殷格翰国际有限公司 容器、喷雾器及用途
PL3139984T3 (pl) 2014-05-07 2021-11-08 Boehringer Ingelheim International Gmbh Nebulizator
CN106232166B (zh) 2014-05-07 2020-04-14 勃林格殷格翰国际有限公司 喷雾器
CN104474534A (zh) * 2014-12-22 2015-04-01 哈德逊(天津)生物技术有限责任公司 白介素-18抗病毒口腔喷剂
EP3563894B1 (en) 2018-05-04 2021-12-22 Boehringer Ingelheim International GmbH Nebulizer and container
EP4196091A4 (en) * 2020-08-14 2024-02-07 Univ Istanbul Rektoerluegue USE OF A HEPARIN COMPOSITION FOR THE TREATMENT OF VIRAL LUNG DISEASES, ACUTE AND/OR CHRONIC LUNG DISEASES
CN114712336B (zh) * 2020-12-22 2023-11-07 黄嘉若 一种用于肺部给药的水性气溶胶、制备方法和用途

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4153689A (en) * 1975-06-13 1979-05-08 Takeda Chemical Industries, Ltd. Stable insulin preparation for nasal administration
EP0083619A1 (en) * 1981-07-17 1983-07-20 Nordisk Insulinlaboratorium A stable aqueous, therapeutic insulin preparation and a process for preparing it
WO1983003054A1 (en) * 1982-03-03 1983-09-15 Johansen, Kristian, Betton A proces for producing an insulin preparation
US4476116A (en) * 1982-12-10 1984-10-09 Syntex (U.S.A.) Inc. Polypeptides/chelating agent nasal compositions having enhanced peptide absorption
DE3827121A1 (de) * 1988-08-10 1990-02-15 Hoechst Ag Verfahren zur herstellung von des-b30-insulinen und des-b30-insulinderivaten
JPH05508616A (ja) * 1989-02-23 1993-12-02 ローヌー プーラン ローラー インターナショナル(ホウルディングス)インコーポレイテッド 治療用エアロゾル剤
JP2704546B2 (ja) * 1989-04-04 1998-01-26 光利 太良 Atll治療用吸入剤
SG45171A1 (en) * 1990-03-21 1998-01-16 Boehringer Ingelheim Int Atomising devices and methods
US5230884A (en) * 1990-09-11 1993-07-27 University Of Wales College Of Cardiff Aerosol formulations including proteins and peptides solubilized in reverse micelles and process for making the aerosol formulations
IL99699A (en) * 1990-10-10 2002-04-21 Autoimmune Inc Drug with the option of oral, intra-intestinal, or inhaled dosing for suppression of autoimmune response associated with type I diabetes
CA2082951C (en) * 1991-03-15 1999-12-21 Robert M. Platz Pulmonary administration of granulocyte colony stimulating factor
DE4117078A1 (de) * 1991-05-25 1992-11-26 Boehringer Ingelheim Kg Verfahren zur herstellung therapeutisch anwendbarer aerosole
US5888477A (en) * 1993-01-29 1999-03-30 Aradigm Corporation Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin
US5354934A (en) * 1993-02-04 1994-10-11 Amgen Inc. Pulmonary administration of erythropoietin
CA2155933C (en) * 1993-02-12 2000-04-04 James L. Levin Pulmonary administration of scr1 and other complement inhibitory proteins
WO1994021283A1 (en) * 1993-03-24 1994-09-29 Boehringer Ingelheim Pharmaceuticals, Inc. Method for inhibiting pulmonary oxygen toxicity using manganese superoxide dismutase
JPH09501418A (ja) * 1993-07-19 1997-02-10 アムジエン・インコーポレーテツド エアゾル化タンパク質の安定化
JPH07165613A (ja) * 1993-10-19 1995-06-27 Dot:Kk 経鼻吸収薬物用キャリヤおよび生理活性ペプチド組成物
JP3414539B2 (ja) * 1994-05-11 2003-06-09 有限会社ドット 経鼻吸収用組成物
US5541569A (en) * 1995-02-28 1996-07-30 Jang; Huey J. Switch having a circuit breaker
DE19536902A1 (de) * 1995-10-04 1997-04-10 Boehringer Ingelheim Int Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung
US5780440A (en) * 1996-06-17 1998-07-14 Protease Sciences Inc. Treatment of pulmonary disease with protease inhibitors
DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole

Also Published As

Publication number Publication date
YU5600A (sh) 2002-08-12
HK1027749A1 (en) 2001-01-23
EP1527771A3 (de) 2007-02-07
KR20010022636A (ko) 2001-03-26
EE05053B1 (et) 2008-08-15
ATE301987T1 (de) 2005-09-15
PL338421A1 (en) 2000-11-06
UY25122A1 (es) 2000-12-29
RS49705B (sr) 2007-12-31
BG64966B1 (bg) 2006-11-30
EA200000190A1 (ru) 2000-10-30
DK1003478T3 (da) 2005-10-24
DE19733651A1 (de) 1999-02-18
EP1003478B1 (de) 2005-08-17
IL134115A (en) 2006-04-10
MY132852A (en) 2007-10-31
NO20000553L (no) 2000-04-03
HUP0003805A2 (en) 2001-03-28
UA73076C2 (en) 2005-06-15
CN1265583A (zh) 2000-09-06
EE200000065A (et) 2000-10-16
SK285637B6 (sk) 2007-05-03
SK1502000A3 (en) 2000-07-11
BR9811827A (pt) 2000-08-15
EP1527771A2 (de) 2005-05-04
EP1003478A1 (de) 2000-05-31
NO20000553D0 (no) 2000-02-03
HRP980425B1 (en) 2006-10-31
ES2248915T3 (es) 2006-03-16
AR016581A1 (es) 2001-07-25
HRP980425A2 (en) 1999-04-30
DE59813014D1 (de) 2005-09-22
JP2001513492A (ja) 2001-09-04
ZA986931B (en) 1999-07-05
CO4960637A1 (es) 2000-09-25
SI1003478T1 (sl) 2006-02-28
PT1003478E (pt) 2005-11-30
IL134115A0 (en) 2001-04-30
CN1177581C (zh) 2004-12-01
AU753673B2 (en) 2002-10-24
HUP0003805A3 (en) 2002-04-29
BG104130A (en) 2000-09-29
TWI222887B (en) 2004-11-01
US20030064032A1 (en) 2003-04-03
NZ503160A (en) 2001-12-21
WO1999007340A1 (de) 1999-02-18
EA002255B1 (ru) 2002-02-28
AU9157798A (en) 1999-03-01
CA2297174A1 (en) 1999-02-18
ID24200A (id) 2000-07-13

Similar Documents

Publication Publication Date Title
TR200000312T2 (tr) Biyolojik açıdan aktif makro moleküller içeren sulu aerosol karışımları.
PT1123120E (pt) Formulacao medicinal em aerossol
ATE231872T1 (de) Thiazolopyrimidinderivate
BR9805993B1 (pt) composição farmacêutica de aerossol.
YU28499A (sh) Novi preparati, lekova rastvorenih u vodi, za dobijanje aerosola bez potisnog gasa
BR9807848B1 (pt) Composto de arilsulfonamidas e análogos, bem como composição farmacêutica e uso dos mesmos.
UY24553A1 (es) Compuestos insecticidas de tipo 5- amino -4-etilsulfinil-pirazol
PT1091975E (pt) Nova ciclosporina com um perfil de actividade melhorado
IT8921118A0 (it) Composizione per aerosol comprendente nitroglicerina come ingrediente attivo.
FI963070A0 (fi) Klooripyrimidiinivälituotteita
TR200200785T2 (tr) 8-Fenil-6,9-dihidro-[1,2,4] triazolo [3,4-i] purin-5-on türevleri
TR200001012T2 (tr) Yeni ariloksi-alkil-dialkilaminler.
PT1017659E (pt) Tetra-hidronaftalenos substituidos e compostos analogos
ATE398630T1 (de) Zyklische conotoxin-peptide
ECSP024400A (es) Derivados de pleuromutilina que tiene actividad antibacteriana
ES2195040T3 (es) Conjugado que incluye un principio activo, un polipeptido y varios polieteres y su uso como medicamento.
DK1015421T3 (da) Nye phenylamidinderivater, fremgangsmåder til deres fremstilling og deres anvendelse som lægemidler
ES2192610T3 (es) Aminouracilos substituidos.
ATE291586T1 (de) Humanes antibiotisches protein
DE60125232D1 (de) Kleines säurelösliches sporenprotein und seine verwendungen
ATE346087T1 (de) Hepatitis e-virus aus dem schwein und dessen verwendungen
BR9810407A (pt) Compostos fluormetoximino
ES2192034T3 (es) Feniluracilos substituidos con efecto herbicida.
ATE331733T1 (de) Metallhaltige ribonukleotidpolypeptide
BR9813102A (pt) Derivados de ácido metilenobisfosfÈnico novos