SMT201600071B - Derivato di acido pirrolidina-3-ilacetico - Google Patents

Derivato di acido pirrolidina-3-ilacetico

Info

Publication number
SMT201600071B
SMT201600071B SM201600071T SM201600071T SMT201600071B SM T201600071 B SMT201600071 B SM T201600071B SM 201600071 T SM201600071 T SM 201600071T SM 201600071 T SM201600071 T SM 201600071T SM T201600071 B SMT201600071 B SM T201600071B
Authority
SM
San Marino
Prior art keywords
pyrrolidine
acid derivative
ilacetic
ilacetic acid
derivative
Prior art date
Application number
SM201600071T
Other languages
English (en)
Italian (it)
Inventor
Ichiro Yoshida
Tadashi Okabe
Yasunobu Matsumoto
Nobuhisa Watanabe
Yoshiaki Ohashi
Yuji ONIZAWA
Hitoshi Harada
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of SMT201600071B publication Critical patent/SMT201600071B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
SM201600071T 2011-09-13 2016-03-10 Derivato di acido pirrolidina-3-ilacetico SMT201600071B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2011199482 2011-09-13
PCT/JP2012/073171 WO2013039057A1 (ja) 2011-09-13 2012-09-11 ピロリジン-3-イル酢酸誘導体

Publications (1)

Publication Number Publication Date
SMT201600071B true SMT201600071B (it) 2016-04-29

Family

ID=47883287

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201600071T SMT201600071B (it) 2011-09-13 2016-03-10 Derivato di acido pirrolidina-3-ilacetico

Country Status (32)

Country Link
EP (1) EP2757103B1 (ja)
JP (1) JP5829689B2 (ja)
KR (1) KR101963922B1 (ja)
CN (1) CN103764648B (ja)
AR (1) AR087788A1 (ja)
AU (1) AU2012309556B2 (ja)
BR (1) BR112014004267B1 (ja)
CA (1) CA2844617C (ja)
CL (1) CL2014000484A1 (ja)
CY (1) CY1117460T1 (ja)
DK (1) DK2757103T3 (ja)
ES (1) ES2564732T3 (ja)
HK (1) HK1193407A1 (ja)
HR (1) HRP20160166T1 (ja)
HU (1) HUE026824T2 (ja)
IL (1) IL230804A (ja)
JO (1) JO3082B1 (ja)
ME (1) ME02383B (ja)
MX (1) MX358494B (ja)
MY (1) MY169869A (ja)
PE (1) PE20141353A1 (ja)
PL (1) PL2757103T3 (ja)
PT (1) PT2757103E (ja)
RS (1) RS54582B1 (ja)
RU (1) RU2615135C2 (ja)
SG (1) SG11201400163WA (ja)
SI (1) SI2757103T1 (ja)
SM (1) SMT201600071B (ja)
TW (1) TWI543975B (ja)
UA (1) UA112873C2 (ja)
WO (1) WO2013039057A1 (ja)
ZA (1) ZA201400918B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5872105B2 (ja) * 2013-03-12 2016-03-01 エーザイ・アール・アンド・ディー・マネジメント株式会社 ピロリジン−3−イル酢酸誘導体の塩およびその結晶
WO2014142086A1 (ja) * 2013-03-13 2014-09-18 エーザイ・アール・アンド・ディー・マネジメント株式会社 ピロリジン-3-イル酢酸誘導体およびピペリジン-3-イル酢酸誘導体
WO2024083933A1 (en) 2022-10-19 2024-04-25 Astrazeneca Ab 2,4,6-trisubstituted 1,3,5-triazines as modulators of cx 3cr1

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4263391B2 (ja) 2001-03-19 2009-05-13 エーザイ・アール・アンド・ディー・マネジメント株式会社 抗cx3cr1抗体、抗フラクタルカイン抗体及びフラクタルカインの利用
AU2002363236A1 (en) * 2001-10-30 2003-05-12 Millennium Pharmaceuticals, Inc. Compounds, pharmaceutical compositions and methods of use therefor
MXPA06003792A (es) * 2003-10-07 2006-06-14 Astrazeneca Ab Nuevas 4-amino-tiazolo[4,5-d]-pirimidinas 2-sustituidas, utiles como antagonistas del receptor de quimiocina, especialmente cx3cr1.
AR053347A1 (es) * 2005-04-06 2007-05-02 Astrazeneca Ab Derivados de [1,3]tiazolo[4,5-d]pirimidin-2(3h)-ona 5,7-sustituidos
UA90707C2 (en) 2005-04-06 2010-05-25 Астразенека Аб Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives
TW200820973A (en) 2006-09-29 2008-05-16 Astrazeneca Ab Novel compounds 480
CN101522693B (zh) 2006-09-29 2012-01-04 阿斯利康(瑞典)有限公司 5,7-二取代的[1,3]噻唑并[4,5-d]嘧啶-2(3h)-胺衍生物和它们在治疗中的用途
TW200831497A (en) * 2006-10-12 2008-08-01 Epix Delaware Inc Carboxamide compounds and their use
BRPI0908883A2 (pt) * 2008-03-07 2015-09-15 Acraf composto, composição farmacêutica, uso de um composto, e, método para tratar ou prevenir doenças
AR071036A1 (es) 2008-03-26 2010-05-19 Astrazeneca Ab Derivados 5, 7-disustituidos de [1, 3]tiazolo[4, 5-d]pirimidin-2 (3h)-ona, una composicion farmaceutica que los comprende y su uso en el tratamiento de enfermedades mediadas por el receptor cx3cr1.

Also Published As

Publication number Publication date
TWI543975B (zh) 2016-08-01
EP2757103A1 (en) 2014-07-23
AU2012309556A1 (en) 2014-02-27
HUE026824T2 (en) 2016-07-28
MX2014002210A (es) 2014-04-30
TW201311667A (zh) 2013-03-16
EP2757103B1 (en) 2016-01-06
MY169869A (en) 2019-05-27
MX358494B (es) 2018-08-23
UA112873C2 (uk) 2016-11-10
NZ620469A (en) 2015-06-26
BR112014004267A2 (pt) 2017-03-21
ME02383B (me) 2016-06-20
DK2757103T3 (en) 2016-03-07
AU2012309556B2 (en) 2016-09-15
PL2757103T3 (pl) 2016-06-30
JPWO2013039057A1 (ja) 2015-03-26
RU2615135C2 (ru) 2017-04-04
SG11201400163WA (en) 2014-06-27
RU2014107536A (ru) 2015-10-20
CA2844617A1 (en) 2013-03-21
CN103764648B (zh) 2015-07-01
KR101963922B1 (ko) 2019-03-29
AR087788A1 (es) 2014-04-16
CN103764648A (zh) 2014-04-30
CY1117460T1 (el) 2017-04-26
JP5829689B2 (ja) 2015-12-09
SI2757103T1 (sl) 2016-04-29
CL2014000484A1 (es) 2014-08-22
IL230804A (en) 2016-02-29
HK1193407A1 (en) 2014-09-19
WO2013039057A1 (ja) 2013-03-21
PT2757103E (pt) 2016-03-31
BR112014004267B1 (pt) 2021-11-16
JO3082B1 (ar) 2017-03-15
RS54582B1 (en) 2016-08-31
IL230804A0 (en) 2014-03-31
PE20141353A1 (es) 2014-09-26
CA2844617C (en) 2019-03-05
ZA201400918B (en) 2015-07-29
EP2757103A4 (en) 2015-02-18
ES2564732T3 (es) 2016-03-28
HRP20160166T1 (hr) 2016-03-11
KR20140060286A (ko) 2014-05-19

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