SK287496B6 - Polypeptid z H. medicinalis, spôsob jeho prípravy a použitie, farmaceutický prostriedok, polynukleotid, expresný vektor, hostiteľská bunka, protilátka a jej použitie - Google Patents

Polypeptid z H. medicinalis, spôsob jeho prípravy a použitie, farmaceutický prostriedok, polynukleotid, expresný vektor, hostiteľská bunka, protilátka a jej použitie Download PDF

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Publication number
SK287496B6
SK287496B6 SK1290-2001A SK12902001A SK287496B6 SK 287496 B6 SK287496 B6 SK 287496B6 SK 12902001 A SK12902001 A SK 12902001A SK 287496 B6 SK287496 B6 SK 287496B6
Authority
SK
Slovakia
Prior art keywords
polypeptide
saratin
protein
seq
sequence
Prior art date
Application number
SK1290-2001A
Other languages
English (en)
Slovak (sk)
Other versions
SK12902001A3 (sk
Inventor
Wolfgang Strittmatter
Detlef G�Ssow
Uwe Hofmann
J�Rgen Hemberger
Zisi Fotev
Bernhard Scheuble
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of SK12902001A3 publication Critical patent/SK12902001A3/sk
Publication of SK287496B6 publication Critical patent/SK287496B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43536—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SK1290-2001A 1999-03-18 2000-03-10 Polypeptid z H. medicinalis, spôsob jeho prípravy a použitie, farmaceutický prostriedok, polynukleotid, expresný vektor, hostiteľská bunka, protilátka a jej použitie SK287496B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99105530 1999-03-18
EP99109503 1999-05-12
PCT/EP2000/002117 WO2000056885A1 (en) 1999-03-18 2000-03-10 Protein for blocking platelet adhesion

Publications (2)

Publication Number Publication Date
SK12902001A3 SK12902001A3 (sk) 2002-03-05
SK287496B6 true SK287496B6 (sk) 2010-12-07

Family

ID=26152935

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1290-2001A SK287496B6 (sk) 1999-03-18 2000-03-10 Polypeptid z H. medicinalis, spôsob jeho prípravy a použitie, farmaceutický prostriedok, polynukleotid, expresný vektor, hostiteľská bunka, protilátka a jej použitie

Country Status (27)

Country Link
US (3) US6774107B1 (pt)
EP (1) EP1161530B1 (pt)
JP (1) JP4805461B2 (pt)
KR (1) KR100788219B1 (pt)
CN (1) CN1185344C (pt)
AR (1) AR023099A1 (pt)
AT (1) ATE295883T1 (pt)
AU (1) AU767172B2 (pt)
BR (1) BR0009074A (pt)
CA (1) CA2367457C (pt)
CO (1) CO5241328A1 (pt)
CZ (1) CZ301524B6 (pt)
DE (1) DE60020220T2 (pt)
DK (1) DK1161530T3 (pt)
ES (1) ES2240067T3 (pt)
HK (1) HK1045330B (pt)
HU (1) HU228068B1 (pt)
MX (1) MXPA01009363A (pt)
MY (1) MY123371A (pt)
NO (1) NO330769B1 (pt)
PL (1) PL200384B1 (pt)
PT (1) PT1161530E (pt)
RU (1) RU2292351C2 (pt)
SI (1) SI1161530T1 (pt)
SK (1) SK287496B6 (pt)
TR (1) TR200102729T2 (pt)
WO (1) WO2000056885A1 (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012016127A1 (de) 2011-08-31 2013-02-28 Daniel Elias Bioaktive, regenerative Mischung zur Herstellung eines Ergänzungsnahrungsmittels

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1161530B1 (en) 1999-03-18 2005-05-18 MERCK PATENT GmbH Protein for blocking platelet adhesion
MY128992A (en) * 2000-08-25 2007-03-30 Merck Patent Gmbh Saratin for inhibiting platelet adhesion to collagen
CA2453986A1 (en) * 2001-07-18 2003-01-30 Merck Patent Gesellschaft Mit Beschraenkter Haftung Glycoprotein vi fusion proteins
EP1684816B1 (en) 2003-10-28 2009-05-06 Medtronic, Inc. Methods of preparing crosslinked materials and bioprosthetic devices
US8017634B2 (en) 2003-12-29 2011-09-13 President And Fellows Of Harvard College Compositions for treating obesity and insulin resistance disorders
BRPI0515994A (pt) * 2004-10-12 2008-08-19 Univ Michigan State biossìntese de floroglucinol e preparo de 1, 3-dihidróxibenzeno a partir do mesmo
EP1893292A2 (en) * 2005-05-26 2008-03-05 Thomas Jefferson University Method to treat and prevent posterior capsule opacification
US20110034396A1 (en) * 2005-09-28 2011-02-10 Biovascular, Inc. Methods and compositions for inhibiting cell migration and treatment of inflammatory conditions
JP2009510105A (ja) * 2005-09-28 2009-03-12 バイオバスキュラー インコーポレーティッド 血小板および細胞の接着、細胞移動、および炎症を阻止するための方法および組成物
US20080015145A1 (en) 2006-07-11 2008-01-17 Maria Gyongyossy-Issa Mimotope receptors and inhibitors for platelet-platelet and platelet-endothelium interactions
GB2462022B (en) * 2008-06-16 2011-05-25 Biovascular Inc Controlled release compositions of agents that reduce circulating levels of platelets and methods thereof
EP2379084B1 (en) * 2008-10-15 2017-11-22 Ionis Pharmaceuticals, Inc. Modulation of factor 11 expression
WO2012003461A2 (en) 2010-07-02 2012-01-05 Draths Corporation Phloroglucinol synthases and methods of making and using the same
WO2012006245A1 (en) 2010-07-06 2012-01-12 Draths Corporation Phloroglucinol reductase and methods of making and using the same
WO2012006244A1 (en) 2010-07-06 2012-01-12 Draths Corporation Method for producing phloroglucinol and dihydrophloroglucinol
SI3333188T1 (sl) 2010-08-19 2022-04-29 Zoetis Belgium S.A. Protitelesa proti NGF in njihova uporaba
US8790651B2 (en) 2011-07-21 2014-07-29 Zoetis Llc Interleukin-31 monoclonal antibody
WO2013184871A1 (en) 2012-06-06 2013-12-12 Zoetis Llc Caninized anti-ngf antibodies and methods thereof
AU2013292617A1 (en) 2012-07-19 2015-01-22 Zoetis Llc Bovine influenza C virus compositions
WO2014018724A1 (en) 2012-07-27 2014-01-30 Zoetis Llc Tick toxin compositions
CA3033759C (en) 2016-08-17 2022-06-14 Pharmaq As Sea lice vaccine
BR102017005783A2 (pt) * 2017-03-21 2018-10-02 Fund Butantan processo de obtenção de esculptina e seus fragmentos, esculptina recombinante e seus usos
WO2019177690A1 (en) 2018-03-12 2019-09-19 Zoetis Services Llc Anti-ngf antibodies and methods thereof
CN112135628A (zh) 2018-03-16 2020-12-25 硕腾服务有限责任公司 抗白介素31的肽疫苗
KR20230145511A (ko) 2018-03-16 2023-10-17 조에티스 서비시즈 엘엘씨 수의학적 용도를 위한 인터류킨-31 단클론성 항체
MX2020011913A (es) 2018-05-09 2021-01-29 Ionis Pharmaceuticals Inc Compuestos y metodos para la reduccion de la expresion de fxi.
BR112022004488A2 (pt) 2019-09-11 2022-05-31 Zoetis Services Llc Herpesvírus recombinante de vetores de peru que expressam antígenos de patógenos aviários e seus usos
US20220119513A1 (en) 2020-06-08 2022-04-21 Zoetis Services Llc Anti-tgfb antibodies and therapeutic uses thereof
US20210386854A1 (en) 2020-06-15 2021-12-16 Zoetis Services Llc Cell Line for Production of Marek's Disease Virus Vaccine and Methods of Making and Using the Same
EP4225788A2 (en) 2020-10-07 2023-08-16 Zoetis Services LLC Anti-ngf antibodies and methods of use thereof
TW202221039A (zh) 2020-10-19 2022-06-01 美商碩騰服務公司 犬及貓抑瘤素Ｍ受體β之抗體及其用途
CN118076634A (zh) 2021-09-27 2024-05-24 硕腾服务有限责任公司 抗TGFβ1、2、3抗体及其治疗用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5705355A (en) * 1984-03-27 1998-01-06 Transgene, S.A. Hirudin, pharmaceutical compositions comprising it and their use
US4898734A (en) 1988-02-29 1990-02-06 Massachusetts Institute Of Technology Polymer composite for controlled release or membrane formation
IL86857A (en) * 1988-06-24 1994-04-12 Yissum Res Dev Co Platelet-aggregating inhibitory agents from leech saliva and pharmaceutical preparations containing the same
US5182260A (en) * 1989-01-27 1993-01-26 Biogen, Inc. Dna sequences encoding snake venom inhibitors of platelet activation processes for producing those inhibitors and compositions using them
CA2052486A1 (en) * 1990-10-09 1992-04-10 Thomas M. Connolly Protein for inhibiting collagen-stimulated platelet aggregation
GB9022040D0 (en) * 1990-10-10 1990-11-21 Biopharm Ltd Platelet adhesion inhibitor
DE4136513A1 (de) * 1991-11-06 1993-05-13 Basf Ag Neues thrombininhibitorisches protein aus raubwanzen
CN1134451C (zh) * 1993-07-01 2004-01-14 默克专利股份有限公司 胶原蛋白激活的血小板凝集抑制剂
AU7476894A (en) 1993-07-29 1995-02-28 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Method of treating atherosclerosis or restenosis using microtubule stabilizing agent
MX9701720A (es) * 1994-09-12 1997-06-28 Schering Ag Proceso para la fabricacion de una palidipina modificada, inhibidora de la agregacion plaquetaria inducida por colageno.
DE69524971T2 (de) * 1994-10-28 2002-08-29 Vitaleech Bioscience N V Neue familie von proteaseinhibitoren und andere biologisch aktive substanzen
EP1161530B1 (en) * 1999-03-18 2005-05-18 MERCK PATENT GmbH Protein for blocking platelet adhesion
MY128992A (en) * 2000-08-25 2007-03-30 Merck Patent Gmbh Saratin for inhibiting platelet adhesion to collagen

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012016127A1 (de) 2011-08-31 2013-02-28 Daniel Elias Bioaktive, regenerative Mischung zur Herstellung eines Ergänzungsnahrungsmittels
DE202012012998U1 (de) 2011-08-31 2014-06-13 Daniel Elias Bioaktive, regenerative Mischung zur Herstellung eines Ergänzungsnahrungsmittels

Also Published As

Publication number Publication date
KR100788219B1 (ko) 2007-12-26
PL350147A1 (en) 2002-11-04
KR20020008131A (ko) 2002-01-29
PT1161530E (pt) 2005-09-30
SI1161530T1 (en) 2005-10-31
DK1161530T3 (da) 2005-08-08
MXPA01009363A (es) 2002-06-04
DE60020220T2 (de) 2006-05-24
TR200102729T2 (tr) 2002-04-22
HUP0200353A2 (hu) 2002-05-29
JP4805461B2 (ja) 2011-11-02
PL200384B1 (pl) 2008-12-31
AU767172B2 (en) 2003-11-06
SK12902001A3 (sk) 2002-03-05
BR0009074A (pt) 2002-01-02
HK1045330A1 (en) 2002-11-22
ES2240067T3 (es) 2005-10-16
CA2367457A1 (en) 2000-09-28
US7090986B2 (en) 2006-08-15
MY123371A (en) 2006-05-31
US20050065084A1 (en) 2005-03-24
NO330769B1 (no) 2011-07-11
US6962801B2 (en) 2005-11-08
AR023099A1 (es) 2002-09-04
CN1185344C (zh) 2005-01-19
DE60020220D1 (de) 2005-06-23
NO20014506L (no) 2001-11-16
EP1161530A1 (en) 2001-12-12
CO5241328A1 (es) 2003-01-31
CN1344318A (zh) 2002-04-10
CA2367457C (en) 2010-09-21
US20060094079A1 (en) 2006-05-04
RU2292351C2 (ru) 2007-01-27
CZ20013341A3 (cs) 2002-01-16
HUP0200353A3 (en) 2003-12-29
NO20014506D0 (no) 2001-09-17
AU3166200A (en) 2000-10-09
CZ301524B6 (cs) 2010-03-31
ATE295883T1 (de) 2005-06-15
EP1161530B1 (en) 2005-05-18
HU228068B1 (en) 2012-09-28
US6774107B1 (en) 2004-08-10
JP2002539788A (ja) 2002-11-26
WO2000056885A1 (en) 2000-09-28
HK1045330B (zh) 2005-09-09

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20140310