SK287408B6 - Spôsob prípravy medziproduktov na výrobu azetidinónov - Google Patents

Spôsob prípravy medziproduktov na výrobu azetidinónov Download PDF

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Publication number
SK287408B6
SK287408B6 SK1186-2003A SK11862003A SK287408B6 SK 287408 B6 SK287408 B6 SK 287408B6 SK 11862003 A SK11862003 A SK 11862003A SK 287408 B6 SK287408 B6 SK 287408B6
Authority
SK
Slovakia
Prior art keywords
formula
compound
acid
process according
present
Prior art date
Application number
SK1186-2003A
Other languages
English (en)
Slovak (sk)
Other versions
SK11862003A3 (sk
Inventor
Xiaoyong Fu
Timothy L. Mcallister
T. K. Thiruvengadam
Chou-Hong Tann
Original Assignee
Schering Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corporation filed Critical Schering Corporation
Publication of SK11862003A3 publication Critical patent/SK11862003A3/sk
Publication of SK287408B6 publication Critical patent/SK287408B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/22—Oxygen atoms attached in position 2 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
SK1186-2003A 2001-03-28 2002-03-25 Spôsob prípravy medziproduktov na výrobu azetidinónov SK287408B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27928801P 2001-03-28 2001-03-28
PCT/US2002/009123 WO2002079174A2 (en) 2001-03-28 2002-03-25 Enantioselective synthesis of azetidinone intermediate compounds

Publications (2)

Publication Number Publication Date
SK11862003A3 SK11862003A3 (sk) 2004-04-06
SK287408B6 true SK287408B6 (sk) 2010-09-07

Family

ID=23068350

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1186-2003A SK287408B6 (sk) 2001-03-28 2002-03-25 Spôsob prípravy medziproduktov na výrobu azetidinónov

Country Status (29)

Country Link
US (1) US6627757B2 (sr)
EP (1) EP1373230B1 (sr)
JP (1) JP4145663B2 (sr)
KR (1) KR100590342B1 (sr)
CN (1) CN1275949C (sr)
AT (1) ATE305459T1 (sr)
AU (1) AU2002258605B2 (sr)
BG (1) BG66189B1 (sr)
BR (1) BRPI0208384B1 (sr)
CA (1) CA2442219C (sr)
CZ (1) CZ304929B6 (sr)
DE (1) DE60206365T2 (sr)
DK (1) DK1373230T3 (sr)
EA (1) EA006898B1 (sr)
EE (1) EE05453B1 (sr)
ES (1) ES2245733T3 (sr)
HK (1) HK1057546A1 (sr)
HR (1) HRP20030760B1 (sr)
HU (1) HU230229B1 (sr)
IL (2) IL157552A0 (sr)
MX (1) MXPA03008803A (sr)
NZ (1) NZ527852A (sr)
PL (1) PL205952B1 (sr)
RS (1) RS50386B (sr)
SI (1) SI1373230T1 (sr)
SK (1) SK287408B6 (sr)
UA (1) UA75644C2 (sr)
WO (1) WO2002079174A2 (sr)
ZA (1) ZA200306612B (sr)

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Also Published As

Publication number Publication date
WO2002079174A2 (en) 2002-10-10
ATE305459T1 (de) 2005-10-15
UA75644C2 (en) 2006-05-15
MXPA03008803A (es) 2004-02-18
EA006898B1 (ru) 2006-04-28
IL157552A (en) 2009-08-03
EE05453B1 (et) 2011-08-15
CZ304929B6 (cs) 2015-01-28
US6627757B2 (en) 2003-09-30
JP4145663B2 (ja) 2008-09-03
CN1500083A (zh) 2004-05-26
JP2004532210A (ja) 2004-10-21
CN1275949C (zh) 2006-09-20
CZ20032610A3 (en) 2004-03-17
ZA200306612B (en) 2004-10-12
BRPI0208384B1 (pt) 2016-05-31
DE60206365T2 (de) 2006-07-06
RS50386B (sr) 2009-12-31
BR0208384A (pt) 2004-06-15
EP1373230B1 (en) 2005-09-28
BG108168A (en) 2004-09-30
PL363864A1 (en) 2004-11-29
HU230229B1 (hu) 2015-10-28
PL205952B1 (pl) 2010-06-30
HUP0303526A2 (hu) 2004-01-28
YU74803A (sh) 2006-05-25
IL157552A0 (en) 2004-03-28
HK1057546A1 (en) 2004-04-08
KR20030085573A (ko) 2003-11-05
EE200300464A (et) 2003-12-15
HUP0303526A3 (en) 2004-11-29
EA200300970A1 (ru) 2004-04-29
NZ527852A (en) 2005-03-24
HRP20030760B1 (en) 2011-07-31
BG66189B1 (bg) 2011-12-30
CA2442219A1 (en) 2002-10-10
WO2002079174A3 (en) 2003-02-27
DK1373230T3 (da) 2005-11-07
CA2442219C (en) 2007-09-11
US20020193607A1 (en) 2002-12-19
HRP20030760A2 (en) 2004-08-31
KR100590342B1 (ko) 2006-06-15
DE60206365D1 (de) 2005-11-03
ES2245733T3 (es) 2006-01-16
EP1373230A2 (en) 2004-01-02
AU2002258605B2 (en) 2006-01-12
SK11862003A3 (sk) 2004-04-06
SI1373230T1 (sl) 2005-12-31

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Owner name: MERCK SHARP & DOHME CORP., RAHWAY, NJ, US

Effective date: 20121108