EE05453B1 - Protsess asetidinoonvahehendite valmistamiseks - Google Patents

Protsess asetidinoonvahehendite valmistamiseks

Info

Publication number
EE05453B1
EE05453B1 EEP200300464A EEP200300464A EE05453B1 EE 05453 B1 EE05453 B1 EE 05453B1 EE P200300464 A EEP200300464 A EE P200300464A EE P200300464 A EEP200300464 A EE P200300464A EE 05453 B1 EE05453 B1 EE 05453B1
Authority
EE
Estonia
Prior art keywords
preparation
azetidinone intermediates
compound
azetidinone
intermediates
Prior art date
Application number
EEP200300464A
Other languages
English (en)
Inventor
Fu Xiaoyong
L. Mcallister Timothy
K. Thiruvengadam T.
Tann Chou-Hong
Original Assignee
Schering Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corporation filed Critical Schering Corporation
Publication of EE200300464A publication Critical patent/EE200300464A/et
Publication of EE05453B1 publication Critical patent/EE05453B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/22—Oxygen atoms attached in position 2 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
EEP200300464A 2001-03-28 2002-03-25 Protsess asetidinoonvahehendite valmistamiseks EE05453B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27928801P 2001-03-28 2001-03-28
PCT/US2002/009123 WO2002079174A2 (en) 2001-03-28 2002-03-25 Enantioselective synthesis of azetidinone intermediate compounds

Publications (2)

Publication Number Publication Date
EE200300464A EE200300464A (et) 2003-12-15
EE05453B1 true EE05453B1 (et) 2011-08-15

Family

ID=23068350

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300464A EE05453B1 (et) 2001-03-28 2002-03-25 Protsess asetidinoonvahehendite valmistamiseks

Country Status (29)

Country Link
US (1) US6627757B2 (et)
EP (1) EP1373230B1 (et)
JP (1) JP4145663B2 (et)
KR (1) KR100590342B1 (et)
CN (1) CN1275949C (et)
AT (1) ATE305459T1 (et)
AU (1) AU2002258605B2 (et)
BG (1) BG66189B1 (et)
BR (1) BRPI0208384B1 (et)
CA (1) CA2442219C (et)
CZ (1) CZ304929B6 (et)
DE (1) DE60206365T2 (et)
DK (1) DK1373230T3 (et)
EA (1) EA006898B1 (et)
EE (1) EE05453B1 (et)
ES (1) ES2245733T3 (et)
HK (1) HK1057546A1 (et)
HR (1) HRP20030760B1 (et)
HU (1) HU230229B1 (et)
IL (2) IL157552A0 (et)
MX (1) MXPA03008803A (et)
NZ (1) NZ527852A (et)
PL (1) PL205952B1 (et)
RS (1) RS50386B (et)
SI (1) SI1373230T1 (et)
SK (1) SK287408B6 (et)
UA (1) UA75644C2 (et)
WO (1) WO2002079174A2 (et)
ZA (1) ZA200306612B (et)

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US20040132058A1 (en) 2002-07-19 2004-07-08 Schering Corporation NPC1L1 (NPC3) and methods of use thereof
US7135556B2 (en) 2002-07-19 2006-11-14 Schering Corporation NPC1L1 (NPC3) and methods of use thereof
AR040588A1 (es) 2002-07-26 2005-04-13 Schering Corp Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa
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US7871998B2 (en) 2003-12-23 2011-01-18 Astrazeneca Ab Diphenylazetidinone derivatives possessing cholesterol absorption inhibitory activity
EP1723414A4 (en) 2004-01-16 2008-03-26 Merck & Co Inc NPC1L1 (NPC3) AND METHOD FOR IDENTIFYING ITS LIGANDS
JP2008514718A (ja) * 2004-09-29 2008-05-08 シェーリング コーポレイション 置換アゼチドノンおよびｃｂ１アンタゴニストの組み合わせ
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US8308559B2 (en) * 2007-05-07 2012-11-13 Jay Chun Paradise box gaming system
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EA200702464A1 (ru) * 2005-05-11 2008-04-28 Майкробиа, Инк. Способы получения фенольных 4-бифенилилазетидин-2-онов
JP2008545700A (ja) * 2005-05-25 2008-12-18 マイクロビア インコーポレーテッド ４−（ビフェニリル）アゼチジン−２−オンホスホン酸類の製造方法
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BRPI0706623A2 (pt) 2006-01-18 2011-04-12 Schering Corp moduladores de receptor canabinóide
CA2642388C (en) * 2006-02-16 2013-11-05 Kotobuki Pharmaceutical Co., Ltd. Process for preparing optically active alcohols
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EP2059241A1 (en) * 2006-09-05 2009-05-20 Schering Corporation Pharmaceutical combinations for lipid management and in the treatment of atherosclerosis and hepatic steatosis
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Also Published As

Publication number Publication date
CN1500083A (zh) 2004-05-26
HK1057546A1 (en) 2004-04-08
US6627757B2 (en) 2003-09-30
DE60206365T2 (de) 2006-07-06
EA200300970A1 (ru) 2004-04-29
CZ304929B6 (cs) 2015-01-28
SI1373230T1 (sl) 2005-12-31
DK1373230T3 (da) 2005-11-07
CZ20032610A3 (en) 2004-03-17
EE200300464A (et) 2003-12-15
WO2002079174A3 (en) 2003-02-27
EA006898B1 (ru) 2006-04-28
UA75644C2 (en) 2006-05-15
HUP0303526A3 (en) 2004-11-29
CA2442219C (en) 2007-09-11
AU2002258605B2 (en) 2006-01-12
CA2442219A1 (en) 2002-10-10
DE60206365D1 (de) 2005-11-03
JP2004532210A (ja) 2004-10-21
NZ527852A (en) 2005-03-24
BG66189B1 (bg) 2011-12-30
BG108168A (en) 2004-09-30
PL205952B1 (pl) 2010-06-30
ZA200306612B (en) 2004-10-12
YU74803A (sh) 2006-05-25
MXPA03008803A (es) 2004-02-18
KR100590342B1 (ko) 2006-06-15
WO2002079174A2 (en) 2002-10-10
BRPI0208384B1 (pt) 2016-05-31
HUP0303526A2 (hu) 2004-01-28
IL157552A (en) 2009-08-03
EP1373230A2 (en) 2004-01-02
JP4145663B2 (ja) 2008-09-03
CN1275949C (zh) 2006-09-20
US20020193607A1 (en) 2002-12-19
EP1373230B1 (en) 2005-09-28
PL363864A1 (en) 2004-11-29
HRP20030760A2 (en) 2004-08-31
KR20030085573A (ko) 2003-11-05
SK287408B6 (sk) 2010-09-07
IL157552A0 (en) 2004-03-28
ES2245733T3 (es) 2006-01-16
SK11862003A3 (sk) 2004-04-06
HU230229B1 (hu) 2015-10-28
ATE305459T1 (de) 2005-10-15
RS50386B (sr) 2009-12-31
BR0208384A (pt) 2004-06-15
HRP20030760B1 (en) 2011-07-31

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