SK279393B6 - Estery kyseliny bisfenylpiperazínnikotínovej, spôs - Google Patents

Estery kyseliny bisfenylpiperazínnikotínovej, spôs Download PDF

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Publication number
SK279393B6
SK279393B6 SK1585-94A SK158594A SK279393B6 SK 279393 B6 SK279393 B6 SK 279393B6 SK 158594 A SK158594 A SK 158594A SK 279393 B6 SK279393 B6 SK 279393B6
Authority
SK
Slovakia
Prior art keywords
formula
nicotinic acid
bisphenylpiperazine
group
acid ester
Prior art date
Application number
SK1585-94A
Other languages
English (en)
Slovak (sk)
Other versions
SK158594A3 (en
Inventor
Torbjrn Lundstedt
Lisbeth Abramo
Anders Bj�Rk
G�Ran Pettersson
Gunnar Andersson
Curt Nordvi
Wu Jin Chang
Catarina Ludwig
Elisabeth Seifert
Arne Nilsson
Original Assignee
Pharmacia & Upjohn Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Aktiebolag filed Critical Pharmacia & Upjohn Aktiebolag
Publication of SK158594A3 publication Critical patent/SK158594A3/sk
Publication of SK279393B6 publication Critical patent/SK279393B6/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, ***e
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
SK1585-94A 1992-06-25 1993-06-23 Estery kyseliny bisfenylpiperazínnikotínovej, spôs SK279393B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9201956A SE9201956D0 (sv) 1992-06-25 1992-06-25 Novel nicotinicacid esters
PCT/SE1993/000565 WO1994000434A1 (en) 1992-06-25 1993-06-23 Novel nicotinic acid esters

Publications (2)

Publication Number Publication Date
SK158594A3 SK158594A3 (en) 1995-07-11
SK279393B6 true SK279393B6 (sk) 1998-11-04

Family

ID=20386602

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1585-94A SK279393B6 (sk) 1992-06-25 1993-06-23 Estery kyseliny bisfenylpiperazínnikotínovej, spôs

Country Status (27)

Country Link
US (1) US5658910A (ru)
EP (2) EP1120410B1 (ru)
JP (1) JP3306827B2 (ru)
KR (1) KR100302216B1 (ru)
CN (1) CN1085981C (ru)
AT (2) ATE278671T1 (ru)
AU (1) AU681346B2 (ru)
BG (1) BG62000B1 (ru)
CA (1) CA2139112C (ru)
CZ (1) CZ281975B6 (ru)
DE (2) DE69331234T2 (ru)
DK (1) DK0673368T3 (ru)
EE (1) EE03122B1 (ru)
ES (1) ES2169044T3 (ru)
FI (1) FI107151B (ru)
HU (2) HU220613B1 (ru)
IL (1) IL106135A (ru)
NO (1) NO302945B1 (ru)
NZ (1) NZ253823A (ru)
PH (1) PH31417A (ru)
PT (1) PT673368E (ru)
RO (1) RO115725B1 (ru)
RU (1) RU2127732C1 (ru)
SE (1) SE9201956D0 (ru)
SK (1) SK279393B6 (ru)
WO (1) WO1994000434A1 (ru)
ZA (1) ZA934596B (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6632823B1 (en) * 1997-12-22 2003-10-14 Merck & Co., Inc. Substituted pyridine compounds useful as modulators of acetylcholine receptors
DE69919707T2 (de) 1998-06-19 2005-09-01 Chiron Corp., Emeryville Glycogen synthase kinase 3 inhibitoren
US7045519B2 (en) 1998-06-19 2006-05-16 Chiron Corporation Inhibitors of glycogen synthase kinase 3
US11447480B2 (en) * 2018-05-09 2022-09-20 Lg Chem, Ltd. Compound exhibiting enteropeptidase inhibitory activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8701375D0 (sv) * 1987-04-02 1987-04-02 Leo Ab Novel pyridyl- and pyrimidyl derivatives
SE9201239D0 (sv) * 1992-04-21 1992-04-21 Kabi Pharmacia Ab Agents for treating substance abuse disorders
SE9202265D0 (sv) * 1992-07-31 1992-07-31 Kabi Pharmacia Ab Novel- pyridyl and pyrimidylpiperazine derivatives

Also Published As

Publication number Publication date
JP3306827B2 (ja) 2002-07-24
ATE278671T1 (de) 2004-10-15
CZ281975B6 (cs) 1997-04-16
CN1086811A (zh) 1994-05-18
SK158594A3 (en) 1995-07-11
HU210875A9 (en) 1995-08-28
DK0673368T3 (da) 2002-03-18
RU2127732C1 (ru) 1999-03-20
EP0673368B1 (en) 2001-11-28
US5658910A (en) 1997-08-19
CN1085981C (zh) 2002-06-05
RO115725B1 (ro) 2000-05-30
FI946085A (fi) 1994-12-23
FI107151B (fi) 2001-06-15
HUT71406A (en) 1995-11-28
ES2169044T3 (es) 2002-07-01
ATE209634T1 (de) 2001-12-15
CZ327494A3 (en) 1995-09-13
KR100302216B1 (ko) 2001-11-22
DE69331234T2 (de) 2002-08-08
SE9201956D0 (sv) 1992-06-25
HU9403786D0 (en) 1995-02-28
CA2139112A1 (en) 1994-01-06
NZ253823A (en) 1996-01-26
WO1994000434A1 (en) 1994-01-06
NO945022L (no) 1995-02-13
BG99289A (bg) 1995-09-29
JPH07508517A (ja) 1995-09-21
FI946085A0 (fi) 1994-12-23
AU681346B2 (en) 1997-08-28
IL106135A0 (en) 1993-10-20
DE69333655D1 (de) 2004-11-11
HU220613B1 (hu) 2002-03-28
NO945022D0 (no) 1994-12-23
KR950702186A (ko) 1995-06-19
PT673368E (pt) 2002-05-31
ZA934596B (en) 1994-02-14
AU4519393A (en) 1994-01-24
DE69331234D1 (de) 2002-01-10
EP0673368A1 (en) 1995-09-27
EP1120410A1 (en) 2001-08-01
EP1120410B1 (en) 2004-10-06
IL106135A (en) 1999-01-26
RU94046310A (ru) 1996-10-27
BG62000B1 (bg) 1998-12-30
EE03122B1 (et) 1998-10-15
NO302945B1 (no) 1998-05-11
PH31417A (en) 1998-10-29
CA2139112C (en) 2006-03-21

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20100623