SI3319970T1 - Pirido-oksazinon derivati kot TNAP inhibitorji - Google Patents
Pirido-oksazinon derivati kot TNAP inhibitorjiInfo
- Publication number
- SI3319970T1 SI3319970T1 SI201630466T SI201630466T SI3319970T1 SI 3319970 T1 SI3319970 T1 SI 3319970T1 SI 201630466 T SI201630466 T SI 201630466T SI 201630466 T SI201630466 T SI 201630466T SI 3319970 T1 SI3319970 T1 SI 3319970T1
- Authority
- SI
- Slovenia
- Prior art keywords
- pyrido
- tnap inhibitors
- oxazinone derivatives
- oxazinone
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562190145P | 2015-07-08 | 2015-07-08 | |
| EP16775006.6A EP3319970B1 (en) | 2015-07-08 | 2016-07-07 | Pyrido-oxazinone derivatives as tnap inhibitors |
| PCT/US2016/041345 WO2017007943A1 (en) | 2015-07-08 | 2016-07-07 | Pyrido-oxazinone derivatives as tnap inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI3319970T1 true SI3319970T1 (sl) | 2019-12-31 |
Family
ID=57045381
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201630466T SI3319970T1 (sl) | 2015-07-08 | 2016-07-07 | Pirido-oksazinon derivati kot TNAP inhibitorji |
Country Status (29)
| Country | Link |
|---|---|
| US (3) | US9920068B2 (sl) |
| EP (1) | EP3319970B1 (sl) |
| JP (1) | JP6666928B2 (sl) |
| KR (1) | KR102590067B1 (sl) |
| CN (1) | CN107207527B (sl) |
| AU (1) | AU2016291163B2 (sl) |
| CA (1) | CA2962795C (sl) |
| CO (1) | CO2017003830A2 (sl) |
| CY (1) | CY1122477T1 (sl) |
| DK (1) | DK3319970T3 (sl) |
| ES (1) | ES2754480T3 (sl) |
| HK (1) | HK1253572A1 (sl) |
| HR (1) | HRP20192121T1 (sl) |
| HU (1) | HUE046994T2 (sl) |
| IL (1) | IL251005B (sl) |
| LT (1) | LT3319970T (sl) |
| MX (1) | MX2017003822A (sl) |
| MY (1) | MY185558A (sl) |
| NZ (1) | NZ729387A (sl) |
| PH (1) | PH12018500066A1 (sl) |
| PL (1) | PL3319970T3 (sl) |
| PT (1) | PT3319970T (sl) |
| RS (1) | RS59594B1 (sl) |
| RU (1) | RU2715704C2 (sl) |
| SG (1) | SG11201701378WA (sl) |
| SI (1) | SI3319970T1 (sl) |
| TW (1) | TWI702220B (sl) |
| WO (1) | WO2017007943A1 (sl) |
| ZA (1) | ZA201701783B (sl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201829417A (zh) * | 2016-12-23 | 2018-08-16 | 日商第一三共股份有限公司 | 氧氮呯化合物 |
| BR112019012782A2 (pt) * | 2016-12-23 | 2020-03-31 | Daiichi Sankyo Company, Limited | Composto, composição farmacêutica, inibidor de tnap, uso de um composto, e, método para tratamento ou profilaxia de uma doença ou condição e para inibir tnap em um indivíduo. |
| JP7449283B2 (ja) | 2018-10-23 | 2024-03-13 | 第一三共株式会社 | ビアリール誘導体 |
| CN114085911B (zh) * | 2022-01-19 | 2022-05-17 | 珠海圣美生物诊断技术有限公司 | 一种检测肿瘤细胞或肿瘤细胞碎片的方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4810795A (en) | 1982-09-30 | 1989-03-07 | A. H. Robins Company, Incorporated | Certain 2,5 and 2,5,6-di- and tri-substituted nicotinic acid intermediates |
| CA2352612A1 (en) | 1998-11-27 | 2000-06-08 | Hideo Fukui | Pharmaceuticals |
| US6410520B2 (en) * | 2000-02-01 | 2002-06-25 | The Procter & Gamble Company | Selective crystallization of 3-pyridyl-1-hydroxyethylidene-1, 1-bisphosphonic acid sodium as the hemipentahydrate or monohydrate |
| JP2009500442A (ja) | 2005-07-09 | 2009-01-08 | アストラゼネカ アクチボラグ | ２型糖尿病を処置するためのグルコキナーゼのモジュレーターとしての２−ヘテロシクリルオキシベンゾイルアミノヘテロシクリル化合物 |
| US8119693B2 (en) | 2007-05-08 | 2012-02-21 | Sanford-Burnham Medical Research Institute | Tissue non-specific alkaline phosphatase inhibitors and uses thereof for treating vascular calcification |
| KR102083041B1 (ko) | 2012-02-22 | 2020-05-27 | 샌포드 번햄 프레비즈 메디컬 디스커버리 인스티튜트 | 술폰아미드 화합물 및 ｔｎａｐ 억제제로서 용도 |
-
2016
- 2016-07-07 HU HUE16775006A patent/HUE046994T2/hu unknown
- 2016-07-07 PT PT167750066T patent/PT3319970T/pt unknown
- 2016-07-07 CN CN201680006507.5A patent/CN107207527B/zh active Active
- 2016-07-07 CA CA2962795A patent/CA2962795C/en active Active
- 2016-07-07 RS RS20191522A patent/RS59594B1/sr unknown
- 2016-07-07 AU AU2016291163A patent/AU2016291163B2/en active Active
- 2016-07-07 EP EP16775006.6A patent/EP3319970B1/en active Active
- 2016-07-07 US US15/314,887 patent/US9920068B2/en active Active
- 2016-07-07 LT LT16775006T patent/LT3319970T/lt unknown
- 2016-07-07 SG SG11201701378WA patent/SG11201701378WA/en unknown
- 2016-07-07 DK DK16775006T patent/DK3319970T3/da active
- 2016-07-07 PL PL16775006T patent/PL3319970T3/pl unknown
- 2016-07-07 SI SI201630466T patent/SI3319970T1/sl unknown
- 2016-07-07 KR KR1020177010518A patent/KR102590067B1/ko active IP Right Grant
- 2016-07-07 RU RU2017117179A patent/RU2715704C2/ru active
- 2016-07-07 TW TW105121542A patent/TWI702220B/zh active
- 2016-07-07 NZ NZ729387A patent/NZ729387A/en unknown
- 2016-07-07 MY MYPI2017700569A patent/MY185558A/en unknown
- 2016-07-07 JP JP2017556523A patent/JP6666928B2/ja active Active
- 2016-07-07 MX MX2017003822A patent/MX2017003822A/es active IP Right Grant
- 2016-07-07 WO PCT/US2016/041345 patent/WO2017007943A1/en active Application Filing
- 2016-07-07 ES ES16775006T patent/ES2754480T3/es active Active
-
2017
- 2017-03-07 IL IL251005A patent/IL251005B/en active IP Right Grant
- 2017-03-13 ZA ZA2017/01783A patent/ZA201701783B/en unknown
- 2017-04-06 US US15/481,151 patent/US9879032B2/en active Active
- 2017-04-20 CO CONC2017/0003830A patent/CO2017003830A2/es unknown
-
2018
- 2018-01-05 PH PH12018500066A patent/PH12018500066A1/en unknown
- 2018-01-18 US US15/874,768 patent/US10221195B2/en active Active
- 2018-10-08 HK HK18112777.4A patent/HK1253572A1/zh unknown
-
2019
- 2019-11-27 CY CY20191101247T patent/CY1122477T1/el unknown
- 2019-11-27 HR HRP20192121TT patent/HRP20192121T1/hr unknown
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