SI2643342T1 - Novi agononisti receptorja angiotensina tip 2 (at2) in njihova uporaba - Google Patents

Novi agononisti receptorja angiotensina tip 2 (at2) in njihova uporaba

Info

Publication number
SI2643342T1
SI2643342T1 SI201131228T SI201131228T SI2643342T1 SI 2643342 T1 SI2643342 T1 SI 2643342T1 SI 201131228 T SI201131228 T SI 201131228T SI 201131228 T SI201131228 T SI 201131228T SI 2643342 T1 SI2643342 T1 SI 2643342T1
Authority
SI
Slovenia
Prior art keywords
receptor agonists
angiotensin type
novel angiotensin
novel
type
Prior art date
Application number
SI201131228T
Other languages
English (en)
Inventor
Vries Louwe De
Sieger Adriaan Nelemans
Rick Rink
Antonius Jacobus Marinus Roks
Gert Nikolaas Moll
Original Assignee
Lanthiopep B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lanthiopep B.V. filed Critical Lanthiopep B.V.
Publication of SI2643342T1 publication Critical patent/SI2643342T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/14Angiotensins: Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
SI201131228T 2010-11-23 2011-11-22 Novi agononisti receptorja angiotensina tip 2 (at2) in njihova uporaba SI2643342T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10192208A EP2455388A1 (en) 2010-11-23 2010-11-23 Novel angiotensin type 2 (AT2) receptor agonists and uses thereof.
EP11791636.1A EP2643342B1 (en) 2010-11-23 2011-11-22 Novel angiotensin type 2 (at2) receptor agonists and uses thereof
PCT/NL2011/050793 WO2012070936A1 (en) 2010-11-23 2011-11-22 Novel angiotensin type 2 (at2) receptor agonists and uses thereof

Publications (1)

Publication Number Publication Date
SI2643342T1 true SI2643342T1 (sl) 2017-08-31

Family

ID=44072497

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201131228T SI2643342T1 (sl) 2010-11-23 2011-11-22 Novi agononisti receptorja angiotensina tip 2 (at2) in njihova uporaba

Country Status (19)

Country Link
US (4) US9290540B2 (sl)
EP (2) EP2455388A1 (sl)
JP (2) JP5837087B2 (sl)
KR (1) KR101512916B1 (sl)
CN (1) CN103314006B (sl)
AU (1) AU2011332397B2 (sl)
CA (1) CA2818299C (sl)
CY (1) CY1119036T1 (sl)
DK (1) DK2643342T3 (sl)
ES (1) ES2632553T3 (sl)
HR (1) HRP20171048T1 (sl)
HU (1) HUE035167T2 (sl)
LT (1) LT2643342T (sl)
NZ (1) NZ610732A (sl)
PL (1) PL2643342T3 (sl)
PT (1) PT2643342T (sl)
RS (1) RS56130B1 (sl)
SI (1) SI2643342T1 (sl)
WO (1) WO2012070936A1 (sl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR102013023224B1 (pt) * 2012-09-14 2023-02-07 Universidade Federal De Minas Gerais PEPTÍDEO (ARGº)N-ANGIOTENSINA-(1-7) E COMPOSIÇÕES FARMACÊUTICAS PARA TRATAMENTO DE DOENÇAS
US8633158B1 (en) * 2012-10-02 2014-01-21 Tarix Pharmaceuticals Ltd. Angiotensin in treating brain conditions
AU2014284496A1 (en) * 2013-07-03 2016-01-21 The Arizona Board Of Regents On Behalf Of The University Of Arizona Method for treating cognitive dysfunction
US10183055B2 (en) 2014-07-21 2019-01-22 Arizona Board Of Regents On Behalf Of The University Of Arizona Ang-(1-7) derivative oligopeptides for the treatment of pain and other indications
WO2016014342A2 (en) 2014-07-21 2016-01-28 Arizona Board Of Regents For The University Of Arizona Ang-(1-7) derviative oligopeptides and methods for using and producing the same
CA2968053A1 (en) * 2014-11-19 2016-05-26 Novopyxis Inc. Compositions and methods for modulating at2r activity
WO2016107879A2 (en) * 2014-12-30 2016-07-07 Vicore Pharma Ab New use of angiotensin ii receptor agonists
US20210238229A1 (en) * 2018-06-14 2021-08-05 University College Cork - National University Of Ireland, Cork Peptide for disease treatment
CN110333302A (zh) * 2019-06-25 2019-10-15 武汉兴华智慧医药科技有限公司 乙酰半胱氨酸溶液中n,n-二乙酰基羊毛硫氨酸的检测方法
CN114514032A (zh) * 2019-08-02 2022-05-17 兰提欧派普有限公司 用于治疗癌症的血管紧张素2型(at2)受体激动剂
KR102488519B1 (ko) * 2020-07-22 2023-01-13 순천대학교 산학협력단 신규 고리형 펜타뎁시펩타이드 화합물 및 이를 유효성분으로 함유하는 상처 치유 또는 재생용 조성물

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6443695A (en) 1987-08-07 1989-02-15 Sun Tech Inc Casing expansion joint device in excavator
US5240928A (en) 1989-07-03 1993-08-31 Merck & Co., Inc. Substituted quinazolinones as angiotensin II antagonists
EP0409332A3 (en) 1989-07-19 1991-08-07 Merck & Co. Inc. Substituted triazoles as angiotensin ii antagonists
US5166206A (en) 1990-03-30 1992-11-24 Merck & Co., Inc. Substituted pyrimidines, pyrimidinones and pyridopyrimidines
US5091390A (en) 1990-09-20 1992-02-25 E. I. Du Pont De Nemours And Company Treatment of CNS disorders with 4,5,6,7-tetrahydro-1H-imidazo (4,5-)-pyridines and analogs
EP0481614A1 (en) 1990-10-01 1992-04-22 Merck & Co. Inc. Substituted pyridopyrimidinones and related heterocycles as angiotensin II antagonists
US5250521A (en) 1990-12-07 1993-10-05 Merck & Co., Inc. Substituted pyrazolopyrimidines as angiotensin II antagonists
US5260285A (en) 1990-12-07 1993-11-09 Merck & Co., Inc. Substituted imidazopyridazines as angiotensin II antagonists
CA2062558A1 (en) 1991-03-08 1992-09-09 Prasun K. Chakravarty Heterocyclic compounds bearing acidic functional groups as angiotensin ii antagonists
US5177074A (en) 1991-03-26 1993-01-05 Merck & Co., Inc. Angiotensin ii antagonists incorporating a substituted thiophene or furan
US5252574A (en) 1991-04-26 1993-10-12 Merck & Co., Inc. Angiotensin II antagonists incorporating a substituted thiophene or furan
US5198438A (en) 1991-05-07 1993-03-30 Merck & Co., Inc. Angiotensin ii antagonists incorporating a substituted thiophene or furan
AU675660B2 (en) 1992-07-17 1997-02-13 Merck & Co., Inc. Substituted biphenylmethylimidazopyridines
US5312820A (en) 1992-07-17 1994-05-17 Merck & Co., Inc. Substituted carbamoyl and oxycarbonyl derivatives of biphenylmethylamines
US5310929A (en) 1992-08-06 1994-05-10 E. I. Du Pont De Nemours And Company Prodrugs of imidazole carboxylic acids as angiotensin II receptor antagonists
US5376666A (en) 1992-11-30 1994-12-27 The Du Pont Merck Pharmaceutical Company Angiotension-II receptor blocking, azacycloalkyl or azacycloalkenyl
WO1994027597A1 (en) 1993-05-21 1994-12-08 Smithkline Beecham Corporation Imidazolyl-alkenoic acid angiotensin ii receptor antagonists
FR2716882B1 (fr) 1994-03-04 1996-04-05 Roussel Uclaf Utilisation de dérivés de l'imidazole au traitement d'affections impliquant les récepteurs AT1 et AT2 de l'Angiotensine, certains de ces produits, leur préparation, compositions pharmaceutiques.
US5834432A (en) 1995-06-06 1998-11-10 The University Of Southern California Use of angiotensin II Type 2 receptor agonists in tissue repair
JPH10203981A (ja) 1997-01-21 1998-08-04 Kureha Chem Ind Co Ltd 心疾患改善剤
WO1998033813A2 (en) 1997-02-04 1998-08-06 University Of Southern California Method for accelerating healing of thermal injuries
AU748903B2 (en) 1997-06-24 2002-06-13 Proteus Molecular Design Limited Angiotensin derivatives
EP1047441A1 (en) 1997-11-26 2000-11-02 University Of Southern California Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation
CA2319701C (en) 1998-02-09 2009-09-29 University Of Southern California Method of promoting erythropoiesis
WO1999040107A2 (en) 1998-02-09 1999-08-12 University Of Southern California Method of promoting keratinocyte proliferation
WO1999039743A2 (en) 1998-02-09 1999-08-12 University Of Southern California Method of promoting hepatic cell proliferation
WO1999042122A1 (en) 1998-02-19 1999-08-26 University Of Southern California Method of promoting embryonic stem cell proliferation
SE9800550D0 (sv) 1998-02-24 1998-02-24 A & Science Invest Ab A pharmaceutical preparation comprising an angiotensin II type 2 receptor agonist, and use thereof
CA2323237C (en) 1998-03-10 2009-05-19 University Of Southern California Improved radiation therapy methods
AU3077299A (en) 1998-03-11 1999-09-27 University Of Southern California Method of promoting production of living tissue equivalents
JP2002511416A (ja) 1998-04-09 2002-04-16 ユニヴァースティ オブ サザーン カリフォルニア 感染を処置および予防するための方法
EP1073453B1 (en) 1998-05-11 2005-04-13 University Of Southern California Use of angiotensin analogs for the manufacture of a medicament for increasing white blood cell survival and mobilizing haematopoietic progenitor cells following chemotherapy
AU756785B2 (en) 1998-07-13 2003-01-23 University Of Southern California Methods for accelerating bone and cartilage growth and repair
EP1105149A1 (en) 1998-08-13 2001-06-13 University Of Southern California Methods to increase blood flow to ischemic tissue
NZ587909A (en) 1998-12-23 2012-05-25 Novartis Ag Process of making a compressed tablets containing valsartan and microcrystalline cellulose
AU756156B2 (en) 1999-03-23 2003-01-02 University Of Southern California Methods for limiting scar and adhesion formation
ATE372987T1 (de) 2001-05-31 2007-09-15 Vicore Pharma Ab Trizyklische verbindungen, nützlich als angiotensin ii agonisten
WO2004046128A1 (en) 2002-11-21 2004-06-03 Vicore Pharma Ab New bicyclic angiotensin ii agonists
WO2008130217A1 (en) 2006-08-08 2008-10-30 Applied Nanosystems B.V. Cyclic angiotensin analogs
BRPI0800585B8 (pt) 2008-02-13 2021-05-25 Univ Minas Gerais composições farmacêuticas do peptídeo des-[asp1]-[ala1]-angiotensina-(1-7) e uso do peptídeo des-[asp1]-[ala1]-angiotensina-(1-7)

Also Published As

Publication number Publication date
LT2643342T (lt) 2017-09-11
CY1119036T1 (el) 2018-01-10
JP2014503506A (ja) 2014-02-13
AU2011332397B2 (en) 2015-11-05
HRP20171048T1 (hr) 2017-10-06
HUE035167T2 (en) 2018-05-02
US20140094400A1 (en) 2014-04-03
KR101512916B1 (ko) 2015-04-16
US20160220632A1 (en) 2016-08-04
KR20130099178A (ko) 2013-09-05
RS56130B1 (sr) 2017-10-31
US20190135867A1 (en) 2019-05-09
EP2643342B1 (en) 2017-04-12
US9707268B2 (en) 2017-07-18
US9290540B2 (en) 2016-03-22
JP2016074675A (ja) 2016-05-12
AU2011332397A1 (en) 2013-05-02
PT2643342T (pt) 2017-07-12
EP2455388A1 (en) 2012-05-23
DK2643342T3 (en) 2017-07-24
US20170283465A1 (en) 2017-10-05
ES2632553T3 (es) 2017-09-14
CA2818299A1 (en) 2012-05-31
NZ610732A (en) 2014-05-30
CN103314006A (zh) 2013-09-18
CN103314006B (zh) 2016-04-13
US10214563B2 (en) 2019-02-26
PL2643342T3 (pl) 2017-09-29
CA2818299C (en) 2018-12-04
EP2643342A1 (en) 2013-10-02
WO2012070936A1 (en) 2012-05-31
JP5837087B2 (ja) 2015-12-24

Similar Documents

Publication Publication Date Title
HUS2100032I1 (hu) Helyettesített 5-fluor-1H-pirazolopiridin-származékok és alkalmazásuk
PT2643342T (pt) Novos agonistas do recetor de angiotensina tipo 2 (at2) e sua utilização
IL222961A0 (en) Novel dna-dinding proteins and uses thereof
HK1185368A1 (en) Heat-curable polyorganosiloxane composition and use thereof
EP2552953A4 (en) FRIZZLED-BINDING SUBSTANCES AND ITS USES
PT2946791T (pt) Anticorpos anti-cd277 e suas utilizações
EP2638065A4 (en) ACTRIIA BINDING AGENTS AND USES THEREOF
HK1179981A1 (zh) 的抗體及其用途
HRP20160922T1 (hr) Oligopeptidni spojevi i njihove uporabe
HK1180720A1 (en) Stabilized alpha galactosidase and uses thereof
PL2588491T3 (pl) Nowy peptyd i jego zastosowanie
IL210773A0 (en) Neuropeptide-2 receptor (y-2r) agonists and uses thereof
EP2632952A4 (en) ANTI-SOD1 ANTIBODIES AND USES THEREOF
IL212364A0 (en) Neuropeptide-2-receptor (y-2r) agonists and uses thereof
EP2608785A4 (en) LIPOMA CYCLES AND ITS USES
IL219987A0 (en) Dp2 antagonist and uses thereof
EP2610619A4 (en) HEMOCININE-1 RECEPTOR AND HEMOCININE-1-PEPTIDE
EP2529013A4 (en) NOVEL BETA GLUCOSIDASE AND USES THEREOF
HK1166493A1 (zh) 維生素 受體激動劑及其用途
EP2545378A4 (en) ANTI-LG3 ANTIBODIES AND USES THEREOF
EP2619580A4 (en) SOLUTION MICROARRAYS AND USES THEREOF
EP2544677A4 (en) BETA-ADRENERGIC RECEPTOR AGONISTS AND USES THEREOF
GB201011848D0 (en) Bale handler "portabale"
GB201002934D0 (en) You're secure
GB201014319D0 (en) Compounds and uses thereof