SI2555754T1 - Trdne farmacevtske oblike 3-(6-(1-(2,2-difluoro-benzo(d)(1,3)dioksol-5- il)ciklopropankarboksamido)-3-metilpiridin-2-il)benzojske kisline - Google Patents
Trdne farmacevtske oblike 3-(6-(1-(2,2-difluoro-benzo(d)(1,3)dioksol-5- il)ciklopropankarboksamido)-3-metilpiridin-2-il)benzojske kislineInfo
- Publication number
- SI2555754T1 SI2555754T1 SI201130836A SI201130836A SI2555754T1 SI 2555754 T1 SI2555754 T1 SI 2555754T1 SI 201130836 A SI201130836 A SI 201130836A SI 201130836 A SI201130836 A SI 201130836A SI 2555754 T1 SI2555754 T1 SI 2555754T1
- Authority
- SI
- Slovenia
- Prior art keywords
- cyclopropanecarboxamido
- difluorobenzo
- dioxol
- methylpyridin
- benzoic acid
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32172910P | 2010-04-07 | 2010-04-07 | |
PCT/US2011/031588 WO2011127290A2 (en) | 2010-04-07 | 2011-04-07 | Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid |
EP11714625.8A EP2555754B1 (en) | 2010-04-07 | 2011-04-07 | Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
SI2555754T1 true SI2555754T1 (sl) | 2016-07-29 |
Family
ID=44625823
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201130836A SI2555754T1 (sl) | 2010-04-07 | 2011-04-07 | Trdne farmacevtske oblike 3-(6-(1-(2,2-difluoro-benzo(d)(1,3)dioksol-5- il)ciklopropankarboksamido)-3-metilpiridin-2-il)benzojske kisline |
Country Status (26)
Country | Link |
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US (5) | US8507687B2 (sl) |
EP (1) | EP2555754B1 (sl) |
JP (2) | JP2013523836A (sl) |
CN (2) | CN105037334A (sl) |
AR (1) | AR081069A1 (sl) |
AU (1) | AU2011237494C1 (sl) |
BR (1) | BR112012026257A2 (sl) |
CA (1) | CA2795748C (sl) |
CY (1) | CY1117728T1 (sl) |
DK (1) | DK2555754T3 (sl) |
ES (1) | ES2579965T3 (sl) |
HK (1) | HK1217327A1 (sl) |
HR (1) | HRP20160682T1 (sl) |
HU (1) | HUE029611T2 (sl) |
IL (1) | IL222332A0 (sl) |
ME (1) | ME02446B (sl) |
MX (1) | MX2012011655A (sl) |
NZ (1) | NZ602795A (sl) |
PL (1) | PL2555754T3 (sl) |
RS (1) | RS54783B1 (sl) |
RU (1) | RU2579370C2 (sl) |
SI (1) | SI2555754T1 (sl) |
SM (1) | SMT201600174B (sl) |
TW (1) | TWI549950B (sl) |
WO (1) | WO2011127290A2 (sl) |
ZA (1) | ZA201207947B (sl) |
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US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
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US7977322B2 (en) | 2004-08-20 | 2011-07-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
EP2530075A3 (en) | 2004-06-24 | 2014-12-24 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
CA2618057A1 (en) | 2005-08-11 | 2007-02-22 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator |
HUE032640T2 (en) | 2005-11-08 | 2017-10-30 | Vertex Pharma | Heterocyclic modulator of ATP-binding cassette transcripts |
AU2006332726B2 (en) | 2005-12-28 | 2012-12-13 | Vertex Pharmaceuticals Incorporated. | Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
AU2006336504C9 (en) | 2005-12-28 | 2015-05-14 | Vertex Pharmaceuticals Incorporated | 1-(benzo [D] [1,3] dioxol-5-yl) -N- (phenyl) cyclopropane- carboxamide derivatives and related compounds as modulators of ATP-Binding Cassette transporters for the treatment of Cystic Fibrosis |
PL3091011T3 (pl) | 2006-04-07 | 2018-06-29 | Vertex Pharmaceuticals Incorporated | Modulatory transporterów posiadających kasetę wiążącą ATP |
US10022352B2 (en) | 2006-04-07 | 2018-07-17 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
US7645789B2 (en) | 2006-04-07 | 2010-01-12 | Vertex Pharmaceuticals Incorporated | Indole derivatives as CFTR modulators |
US8563573B2 (en) | 2007-11-02 | 2013-10-22 | Vertex Pharmaceuticals Incorporated | Azaindole derivatives as CFTR modulators |
US8969386B2 (en) | 2007-05-09 | 2015-03-03 | Vertex Pharmaceuticals Incorporated | Modulators of CFTR |
AU2008302598B2 (en) | 2007-08-24 | 2014-07-17 | Vertex Pharmaceuticals Incorporated | Isothiazolopyridinones useful for the treatment of (inter alia) Cystic Fibrosis |
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