SI2204374T1 - Nukleozidni fosfonati in njihovi analogi za zdravljenje HPV-infekcij - Google Patents

Nukleozidni fosfonati in njihovi analogi za zdravljenje HPV-infekcij

Info

Publication number: SI2204374T1
Authority: SI; Slovenia
Prior art keywords: hpv; analogs; infections; treatment; nucleoside phosphonates
Prior art date: 2003-12-30

Application number

SI200431910T

Other languages

English (en)

Inventor

Xiaqin Cheng

Gary P Cook

Manoj C Desai

Edward Doerffler

Gong-Xin He

Choung U Kim

William A Lee

John C Rohloff

Jianying Wang

Zheng-Yu Yang

Original Assignee

Gilead Sciences Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-12-30

Filing date

2004-12-29

Publication date

2012-09-28

2004-12-29 Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc

2012-09-28 Publication of SI2204374T1 publication Critical patent/SI2204374T1/sl

Links

-1 Nucleoside phosphonates Chemical class 0.000 title 1
208000009608 Papillomavirus Infections Diseases 0.000 title 1
239000002777 nucleoside Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/44—Amides thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/664—Amides of phosphorus acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Biochemistry (AREA)
Virology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

SI200431910T 2003-12-30 2004-12-29 Nukleozidni fosfonati in njihovi analogi za zdravljenje HPV-infekcij SI2204374T1 (sl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US53374503P	2003-12-30	2003-12-30
US59098704P	2004-07-26	2004-07-26
US60659504P	2004-09-01	2004-09-01
EP10158740A EP2204374B1 (en)	2003-12-30	2004-12-29	Nucleoside phosphonates and analogs thereof for the treatment of HPV-infections

Publications (1)

Publication Number	Publication Date
SI2204374T1 true SI2204374T1 (sl)	2012-09-28

Family

ID=34753695

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SI200431910T SI2204374T1 (sl)	2003-12-30	2004-12-29	Nukleozidni fosfonati in njihovi analogi za zdravljenje HPV-infekcij
SI200431534T SI1716162T1 (sl)	2003-12-30	2004-12-29	Fosfonati, monofosfonamidati, bisfosfonamidati za zdravljenje virusnih bolezni

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SI200431534T SI1716162T1 (sl)	2003-12-30	2004-12-29	Fosfonati, monofosfonamidati, bisfosfonamidati za zdravljenje virusnih bolezni

Country Status (28)

Country	Link
US (5)	US7553825B2 (sl)
EP (2)	EP1716162B1 (sl)
JP (2)	JP4949852B2 (sl)
KR (2)	KR20120080240A (sl)
CN (2)	CN1950383B (sl)
AP (1)	AP2212A (sl)
AT (1)	ATE478082T1 (sl)
AU (2)	AU2004312546B2 (sl)
BR (1)	BRPI0418251C1 (sl)
CA (1)	CA2550222C (sl)
CY (2)	CY1111050T1 (sl)
DE (1)	DE602004028763D1 (sl)
DK (2)	DK1716162T3 (sl)
EA (1)	EA011304B1 (sl)
ES (2)	ES2389602T3 (sl)
HK (2)	HK1097276A1 (sl)
HR (3)	HRP20060254A2 (sl)
IL (1)	IL176407A (sl)
IS (1)	IS2994B (sl)
NO (2)	NO338001B1 (sl)
NZ (1)	NZ548771A (sl)
PL (3)	PL2204374T3 (sl)
PT (2)	PT2204374E (sl)
RS (2)	RS51476B (sl)
SG (1)	SG149075A1 (sl)
SI (2)	SI2204374T1 (sl)
WO (1)	WO2005066189A1 (sl)
ZA (1)	ZA200606049B (sl)

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2004
- 2004-12-29 AP AP2006003675A patent/AP2212A/xx active
- 2004-12-29 BR BRPI0418251A patent/BRPI0418251C1/pt active Search and Examination
- 2004-12-29 AU AU2004312546A patent/AU2004312546B2/en active Active
- 2004-12-29 EP EP04815956A patent/EP1716162B1/en active Active
- 2004-12-29 PL PL10158740T patent/PL2204374T3/pl unknown
- 2004-12-29 PT PT10158740T patent/PT2204374E/pt unknown
- 2004-12-29 PL PL04815956T patent/PL1716162T3/pl unknown
- 2004-12-29 EA EA200601263A patent/EA011304B1/ru not_active IP Right Cessation
- 2004-12-29 NZ NZ548771A patent/NZ548771A/en unknown
- 2004-12-29 AT AT04815956T patent/ATE478082T1/de active
- 2004-12-29 US US11/026,303 patent/US7553825B2/en active Active
- 2004-12-29 EP EP10158740A patent/EP2204374B1/en active Active
- 2004-12-29 CA CA2550222A patent/CA2550222C/en active Active
- 2004-12-29 WO PCT/US2004/043969 patent/WO2005066189A1/en active Application Filing
- 2004-12-29 DE DE602004028763T patent/DE602004028763D1/de active Active
- 2004-12-29 KR KR1020127013492A patent/KR20120080240A/ko not_active Application Discontinuation
- 2004-12-29 ES ES10158740T patent/ES2389602T3/es active Active
- 2004-12-29 SG SG200809660-4A patent/SG149075A1/en unknown
- 2004-12-29 CN CN2004800394690A patent/CN1950383B/zh active Active
- 2004-12-29 PL PL380828A patent/PL212403B1/pl unknown
- 2004-12-29 RS RSP-2010/0490A patent/RS51476B/en unknown
- 2004-12-29 SI SI200431910T patent/SI2204374T1/sl unknown
- 2004-12-29 PT PT04815956T patent/PT1716162E/pt unknown
- 2004-12-29 ES ES04815956T patent/ES2350983T3/es active Active
- 2004-12-29 DK DK04815956.0T patent/DK1716162T3/da active
- 2004-12-29 RS RS20120389A patent/RS52433B/en unknown
- 2004-12-29 CN CN2010101456719A patent/CN101816664B/zh active Active
- 2004-12-29 JP JP2006547579A patent/JP4949852B2/ja active Active
- 2004-12-29 SI SI200431534T patent/SI1716162T1/sl unknown
- 2004-12-29 DK DK10158740.0T patent/DK2204374T3/da active
2005
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- 2005-06-29 US US11/170,247 patent/US20060030545A1/en not_active Abandoned
2006
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- 2006-06-21 IS IS8516A patent/IS2994B/is unknown
- 2006-07-19 HR HR20060254A patent/HRP20060254A2/xx not_active Application Discontinuation
- 2006-07-21 ZA ZA2006/06049A patent/ZA200606049B/en unknown
- 2006-07-28 NO NO20063479A patent/NO338001B1/no unknown
- 2006-07-31 KR KR1020067015535A patent/KR101214257B1/ko active IP Right Grant
2007
- 2007-04-30 HK HK07104599.0A patent/HK1097276A1/xx unknown
2009
- 2009-02-18 US US12/388,295 patent/US8088754B2/en active Active
- 2009-05-05 US US12/436,004 patent/US8268802B2/en active Active
2010
- 2010-11-17 CY CY20101101036T patent/CY1111050T1/el unknown
- 2010-11-18 HR HR20100626T patent/HRP20100626T1/hr unknown
2011
- 2011-01-06 HK HK11100117.5A patent/HK1146061A1/xx unknown
- 2011-01-13 AU AU2011200141A patent/AU2011200141B2/en active Active
- 2011-02-25 JP JP2011040828A patent/JP2011137029A/ja not_active Withdrawn
2012
- 2012-09-04 HR HRP20120699TT patent/HRP20120699T1/hr unknown
- 2012-09-10 CY CY20121100813T patent/CY1113103T1/el unknown
2015
- 2015-05-18 NO NO20150615A patent/NO338040B1/no unknown

Also Published As

Publication number	Publication date
RS52433B (en)	2013-02-28
PL380828A1 (pl)	2007-03-19
BRPI0418251B1 (pt)	2019-09-24
ES2389602T3 (es)	2012-10-29
CY1113103T1 (el)	2016-04-13
KR20120080240A (ko)	2012-07-16
CN101816664A (zh)	2010-09-01
SG149075A1 (en)	2009-01-29
WO2005066189A1 (en)	2005-07-21
NO20063479L (no)	2006-10-02
ES2350983T3 (es)	2011-01-28
US8088754B2 (en)	2012-01-03
KR101214257B1 (ko)	2012-12-21
BRPI0418251A (pt)	2007-04-17
US7553825B2 (en)	2009-06-30
ATE478082T1 (de)	2010-09-15
PT2204374E (pt)	2012-09-17
AU2004312546A1 (en)	2005-07-21
IS2994B (is)	2018-03-15
EP2204374A1 (en)	2010-07-07
EP1716162A1 (en)	2006-11-02
CY1111050T1 (el)	2015-06-11
NO338001B1 (no)	2016-07-18
JP2011137029A (ja)	2011-07-14
KR20060129360A (ko)	2006-12-15
US20090291922A1 (en)	2009-11-26
IL176407A (en)	2012-12-31
PL1716162T3 (pl)	2011-02-28
PL2204374T3 (pl)	2012-11-30
PT1716162E (pt)	2010-11-24
EA011304B1 (ru)	2009-02-27
BRPI0418251C1 (pt)	2021-05-25
ZA200606049B (en)	2008-01-08
NO338040B1 (no)	2016-07-25
CN1950383B (zh)	2010-06-09
AP2212A (en)	2011-03-01
HRP20120699T1 (hr)	2012-09-30
DK1716162T3 (da)	2011-01-10
US20060046981A1 (en)	2006-03-02
NO20150615L (no)	2005-07-01
SI1716162T1 (sl)	2010-12-31
JP2007517065A (ja)	2007-06-28
EA200601263A1 (ru)	2006-12-29
CA2550222A1 (en)	2005-07-21
DE602004028763D1 (de)	2010-09-30
AU2011200141B2 (en)	2012-02-16
HRP20100626T1 (hr)	2011-03-31
EP2204374B1 (en)	2012-06-13
HK1146061A1 (en)	2011-05-13
US8268802B2 (en)	2012-09-18
IS8516A (is)	2006-06-21
AU2011200141A1 (en)	2011-02-03
US20050222090A1 (en)	2005-10-06
CN101816664B (zh)	2012-04-18
EP1716162B1 (en)	2010-08-18
US20090149400A1 (en)	2009-06-11
AU2004312546B2 (en)	2010-10-14
PL212403B1 (pl)	2012-09-28
HK1097276A1 (en)	2007-06-22
NZ548771A (en)	2010-05-28
DK2204374T3 (da)	2012-09-10
IL176407A0 (en)	2006-10-05
CA2550222C (en)	2013-05-28
CN1950383A (zh)	2007-04-18
BRPI0418251B8 (pt)	2019-10-08
US20060030545A1 (en)	2006-02-09
HRP20060254A2 (en)	2006-10-31
RS51476B (en)	2011-04-30
JP4949852B2 (ja)	2012-06-13
AP2006003675A0 (en)	2006-08-31

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