SG11201507555PA - Chemical entities - Google Patents
Chemical entitiesInfo
- Publication number
- SG11201507555PA SG11201507555PA SG11201507555PA SG11201507555PA SG11201507555PA SG 11201507555P A SG11201507555P A SG 11201507555PA SG 11201507555P A SG11201507555P A SG 11201507555PA SG 11201507555P A SG11201507555P A SG 11201507555PA SG 11201507555P A SG11201507555P A SG 11201507555PA
- Authority
- SG
- Singapore
- Prior art keywords
- chemical entities
- entities
- chemical
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Steroid Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13382089 | 2013-03-15 | ||
PCT/GB2014/050825 WO2014140644A1 (fr) | 2013-03-15 | 2014-03-14 | Entités chimiques |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201507555PA true SG11201507555PA (en) | 2015-10-29 |
Family
ID=48013903
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201507555PA SG11201507555PA (en) | 2013-03-15 | 2014-03-14 | Chemical entities |
Country Status (32)
Country | Link |
---|---|
US (1) | US9453031B2 (fr) |
EP (1) | EP2970332B1 (fr) |
JP (1) | JP6379115B2 (fr) |
KR (1) | KR102206318B1 (fr) |
CN (1) | CN105051047B (fr) |
AR (1) | AR095443A1 (fr) |
AU (1) | AU2014229735B2 (fr) |
BR (1) | BR112015023060B1 (fr) |
CA (1) | CA2904768C (fr) |
CL (1) | CL2015002591A1 (fr) |
CY (1) | CY1120619T1 (fr) |
DK (1) | DK2970332T3 (fr) |
EA (1) | EA029771B1 (fr) |
ES (1) | ES2670674T3 (fr) |
HK (1) | HK1215021A1 (fr) |
HR (1) | HRP20180839T1 (fr) |
HU (1) | HUE037685T2 (fr) |
IL (1) | IL240708B (fr) |
LT (1) | LT2970332T (fr) |
MX (1) | MX368056B (fr) |
NO (1) | NO2970332T3 (fr) |
NZ (1) | NZ711038A (fr) |
PE (1) | PE20152007A1 (fr) |
PH (1) | PH12015502159B1 (fr) |
PL (1) | PL2970332T3 (fr) |
PT (1) | PT2970332T (fr) |
RS (1) | RS57216B1 (fr) |
SG (1) | SG11201507555PA (fr) |
SI (1) | SI2970332T1 (fr) |
TW (1) | TWI557131B (fr) |
UA (1) | UA118261C2 (fr) |
WO (1) | WO2014140644A1 (fr) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014110574A1 (fr) | 2013-01-14 | 2014-07-17 | Incyte Corporation | Composés de carboxamide aromatique bicyclique utiles comme inhibiteurs de pim kinase |
KR102403306B1 (ko) | 2013-01-15 | 2022-06-02 | 인사이트 홀딩스 코포레이션 | Pim 키나제 저해제로서 유용한 티아졸카복스아마이드 및 피리딘카복스아마이드 화합물 |
US9556197B2 (en) | 2013-08-23 | 2017-01-31 | Incyte Corporation | Furo- and thieno-pyridine carboxamide compounds useful as pim kinase inhibitors |
US9822124B2 (en) | 2014-07-14 | 2017-11-21 | Incyte Corporation | Bicyclic heteroaromatic carboxamide compounds useful as Pim kinase inhibitors |
US9580418B2 (en) | 2014-07-14 | 2017-02-28 | Incyte Corporation | Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors |
WO2016112374A2 (fr) * | 2015-01-09 | 2016-07-14 | The General Hospital Corporation | Traitement du cancer à l'aide d'inhibiteurs de l'atr - ataxie-télangiectasie mutée and rad3 liée - |
WO2016196244A1 (fr) | 2015-05-29 | 2016-12-08 | Incyte Corporation | Composés de pyridineamine utiles en tant qu'inhibiteurs de kinase pim |
AR105967A1 (es) | 2015-09-09 | 2017-11-29 | Incyte Corp | Sales de un inhibidor de pim quinasa |
TW201718546A (zh) | 2015-10-02 | 2017-06-01 | 英塞特公司 | 適用作pim激酶抑制劑之雜環化合物 |
US10570149B2 (en) | 2016-05-24 | 2020-02-25 | Merck Patent Gmbh | Tricyclic heterocylic derivatives |
AR113922A1 (es) | 2017-12-08 | 2020-07-01 | Incyte Corp | Terapia de combinación de dosis baja para el tratamiento de neoplasias mieloproliferativas |
RS65147B1 (sr) * | 2018-02-07 | 2024-02-29 | Wuxi Biocity Biopharmaceutics Co Ltd | Inhibitor atr i njegova primena |
WO2020094084A1 (fr) * | 2018-11-07 | 2020-05-14 | 南京明德新药研发有限公司 | Dérivé tricyclique utilisé comme inhibiteur de ret |
CN113004303A (zh) * | 2019-12-18 | 2021-06-22 | 江苏恒瑞医药股份有限公司 | 嘧啶并噁嗪类三环衍生物、其制备方法及其在医药上的应用 |
TW202140474A (zh) * | 2020-01-17 | 2021-11-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | 稠合雜芳基類衍生物、其製備方法及其在醫藥上的應用 |
WO2022078480A1 (fr) | 2020-10-16 | 2022-04-21 | 上海迪诺医药科技有限公司 | Dérivé trihétérocyclique, ainsi que composition pharmaceutique et application de celui-ci |
CN115466258A (zh) * | 2021-06-11 | 2022-12-13 | 成都苑东生物制药股份有限公司 | Atr抑制剂及其用途 |
CN115286645A (zh) * | 2022-08-16 | 2022-11-04 | 南京雷正医药科技有限公司 | 三环杂环衍生物及其药物组合物和用途 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5583024A (en) | 1985-12-02 | 1996-12-10 | The Regents Of The University Of California | Recombinant expression of Coleoptera luciferase |
AU3427093A (en) * | 1992-01-15 | 1993-08-03 | E.I. Du Pont De Nemours And Company | Bridged heterocyclic fungicides |
JPH08336393A (ja) | 1995-04-13 | 1996-12-24 | Mitsubishi Chem Corp | 光学活性なγ−置換−β−ヒドロキシ酪酸エステルの製造法 |
DK0961780T3 (da) | 1997-02-12 | 2007-08-27 | Electrophoretics Ltd | Proteinmarkörer for lungecancer og anvendelse deraf |
GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
US6602677B1 (en) | 1997-09-19 | 2003-08-05 | Promega Corporation | Thermostable luciferases and methods of production |
GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
KR20080015482A (ko) | 1999-02-10 | 2008-02-19 | 아스트라제네카 아베 | 혈관형성 억제제로서의 퀴나졸린 유도체 |
UA72946C2 (uk) | 1999-11-05 | 2005-05-16 | Астразенека Аб | Похідні хіназоліну як інгібітори васкулярного ендотеліального фактора росту (vegf) |
CA2399358C (fr) | 2000-02-15 | 2006-03-21 | Sugen, Inc. | Inhibiteurs de la proteine kinase 2-indolinone a substitution pyrrole |
CA2406979A1 (fr) | 2000-05-31 | 2001-12-06 | Astrazeneca Ab | Derives d'indole possedant une activite endommageant les vaisseaux sanguins |
UA73993C2 (uk) | 2000-06-06 | 2005-10-17 | Астразенека Аб | Хіназолінові похідні для лікування пухлин та фармацевтична композиція |
RU2003103603A (ru) | 2000-07-07 | 2004-08-20 | Энджиоджен Фармасьютикалз Лимитед (Gb) | Производные колхинола в качестве ингибиторов ангиогенеза |
AU2001266233B2 (en) | 2000-07-07 | 2006-06-29 | Angiogene Pharmaceuticals Limited | Colchinol derivatives as vascular damaging agents |
US8735411B2 (en) * | 2006-10-02 | 2014-05-27 | Abbvie Inc. | Macrocyclic benzofused pyrimidine derivatives |
JP2010508314A (ja) * | 2006-10-30 | 2010-03-18 | ノバルティス アーゲー | 脂質キナーゼ阻害剤としてのイミダゾピリダジン |
MX2009012066A (es) * | 2007-05-09 | 2009-11-19 | Novartis Ag | Imidazopirinas sustituidas como inhibidoras de cinasa de lipido p13k. |
MX2012002059A (es) * | 2009-08-20 | 2012-04-19 | Karus Therapeutics Ltd | Compestos heterociclicos triciclicos como inhibidores de fosfoionositida 3-quinasa. |
CN102020657A (zh) * | 2009-09-11 | 2011-04-20 | 上海艾力斯医药科技有限公司 | 稠合杂芳基衍生物、制备方法及其应用 |
NZ605627A (en) * | 2010-06-23 | 2015-06-26 | Vertex Pharma | Pyrrolo-pyrazine derivatives useful as inhibitors of atr kinase |
BR112013014914B8 (pt) * | 2010-12-16 | 2020-08-04 | Hoffmann La Roche | composto, composição farmacêutica e uso de um composto |
-
2014
- 2014-03-13 AR ARP140100990A patent/AR095443A1/es unknown
- 2014-03-14 UA UAA201510054A patent/UA118261C2/uk unknown
- 2014-03-14 ES ES14716910.6T patent/ES2670674T3/es active Active
- 2014-03-14 CA CA2904768A patent/CA2904768C/fr active Active
- 2014-03-14 DK DK14716910.6T patent/DK2970332T3/en active
- 2014-03-14 AU AU2014229735A patent/AU2014229735B2/en active Active
- 2014-03-14 US US14/774,294 patent/US9453031B2/en active Active
- 2014-03-14 BR BR112015023060-1A patent/BR112015023060B1/pt active IP Right Grant
- 2014-03-14 EA EA201591781A patent/EA029771B1/ru not_active IP Right Cessation
- 2014-03-14 SG SG11201507555PA patent/SG11201507555PA/en unknown
- 2014-03-14 MX MX2015011549A patent/MX368056B/es active IP Right Grant
- 2014-03-14 SI SI201430698T patent/SI2970332T1/en unknown
- 2014-03-14 EP EP14716910.6A patent/EP2970332B1/fr active Active
- 2014-03-14 NO NO14716910A patent/NO2970332T3/no unknown
- 2014-03-14 PT PT147169106T patent/PT2970332T/pt unknown
- 2014-03-14 PE PE2015001900A patent/PE20152007A1/es active IP Right Grant
- 2014-03-14 JP JP2015562337A patent/JP6379115B2/ja active Active
- 2014-03-14 RS RS20180576A patent/RS57216B1/sr unknown
- 2014-03-14 HU HUE14716910A patent/HUE037685T2/hu unknown
- 2014-03-14 CN CN201480015613.0A patent/CN105051047B/zh active Active
- 2014-03-14 TW TW103109396A patent/TWI557131B/zh active
- 2014-03-14 PL PL14716910T patent/PL2970332T3/pl unknown
- 2014-03-14 WO PCT/GB2014/050825 patent/WO2014140644A1/fr active Application Filing
- 2014-03-14 NZ NZ711038A patent/NZ711038A/en unknown
- 2014-03-14 LT LTEP14716910.6T patent/LT2970332T/lt unknown
- 2014-03-14 KR KR1020157025265A patent/KR102206318B1/ko active IP Right Grant
-
2015
- 2015-08-20 IL IL240708A patent/IL240708B/en active IP Right Grant
- 2015-09-10 CL CL2015002591A patent/CL2015002591A1/es unknown
- 2015-09-15 PH PH12015502159A patent/PH12015502159B1/en unknown
-
2016
- 2016-03-14 HK HK16102921.2A patent/HK1215021A1/zh unknown
-
2018
- 2018-05-24 CY CY181100555T patent/CY1120619T1/el unknown
- 2018-05-25 HR HRP20180839TT patent/HRP20180839T1/hr unknown
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