HUP0004286A3 - Use of quinazoline derivatives for producing pharmaceutical compositions for treating colonic polyps - Google Patents

Use of quinazoline derivatives for producing pharmaceutical compositions for treating colonic polyps

Info

Publication number
HUP0004286A3
HUP0004286A3 HU0004286A HUP0004286A HUP0004286A3 HU P0004286 A3 HUP0004286 A3 HU P0004286A3 HU 0004286 A HU0004286 A HU 0004286A HU P0004286 A HUP0004286 A HU P0004286A HU P0004286 A3 HUP0004286 A3 HU P0004286A3
Authority
HU
Hungary
Prior art keywords
pharmaceutical compositions
quinazoline derivatives
producing pharmaceutical
colonic polyps
treating colonic
Prior art date
Application number
HU0004286A
Other languages
Hungarian (hu)
Original Assignee
American Cyanamid Co Madison
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co Madison filed Critical American Cyanamid Co Madison
Publication of HUP0004286A2 publication Critical patent/HUP0004286A2/en
Publication of HUP0004286A3 publication Critical patent/HUP0004286A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU0004286A 1997-11-06 1998-11-04 Use of quinazoline derivatives for producing pharmaceutical compositions for treating colonic polyps HUP0004286A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96508497A 1997-11-06 1997-11-06
PCT/US1998/023549 WO1999024037A1 (en) 1997-11-06 1998-11-04 Use of quinazoline derivatives as tyrosine kinase inhibitors for treating colonic polyps

Publications (2)

Publication Number Publication Date
HUP0004286A2 HUP0004286A2 (en) 2001-11-28
HUP0004286A3 true HUP0004286A3 (en) 2002-01-28

Family

ID=25509419

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0004286A HUP0004286A3 (en) 1997-11-06 1998-11-04 Use of quinazoline derivatives for producing pharmaceutical compositions for treating colonic polyps

Country Status (15)

Country Link
EP (1) EP1039910A1 (en)
JP (1) JP2001522802A (en)
KR (1) KR20010031813A (en)
CN (1) CN1278176A (en)
AR (1) AR016415A1 (en)
AU (1) AU1308799A (en)
BR (1) BR9814116A (en)
CA (1) CA2306155A1 (en)
HU (1) HUP0004286A3 (en)
IL (1) IL135622A0 (en)
NO (1) NO20002166L (en)
NZ (1) NZ503991A (en)
PL (1) PL340800A1 (en)
WO (1) WO1999024037A1 (en)
ZA (1) ZA9810134B (en)

Families Citing this family (146)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60031127T2 (en) * 1999-08-12 2007-02-01 Wyeth Holdings Corp. NSAID AND EGFR KINASE INHIBITORS PHARMACEUTICAL FORMULATION FOR THE TREATMENT OR INHIBITION OF THICK DARMPOLYPES AND COLORECTAL CANCER
US6432979B1 (en) 1999-08-12 2002-08-13 American Cyanamid Company Method of treating or inhibiting colonic polyps and colorectal cancer
US6924285B2 (en) 2002-03-30 2005-08-02 Boehringer Ingelheim Pharma Gmbh & Co. Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
GB0309850D0 (en) 2003-04-30 2003-06-04 Astrazeneca Ab Quinazoline derivatives
JP4724657B2 (en) 2003-05-30 2011-07-13 アストラゼネカ ユーケー リミテッド process
GB0326459D0 (en) 2003-11-13 2003-12-17 Astrazeneca Ab Quinazoline derivatives
ME01267B (en) 2004-05-06 2013-06-20 Warner Lambert Co 4-phenylamino-quinazolin-6-yl-amides
EP1838712B8 (en) 2004-12-14 2011-10-12 AstraZeneca AB Pyrazolopyrimidine compounds as antitumor agents
WO2006071079A1 (en) * 2004-12-29 2006-07-06 Hanmi Pharm. Co., Ltd. Quinazoline derivatives for inhibiting cancer cell growth and method for the preparation thereof
US7820683B2 (en) 2005-09-20 2010-10-26 Astrazeneca Ab 4-(1H-indazol-5-yl-amino)-quinazoline compounds as erbB receptor tyrosine kinase inhibitors for the treatment of cancer
EP2061906B1 (en) 2006-09-12 2011-08-31 Genentech, Inc. Methods and compositions for the diagnosis and treatment of lung cancer using pdgfra, kit or kdr gene as genetic marker
EP1921070A1 (en) 2006-11-10 2008-05-14 Boehringer Ingelheim Pharma GmbH & Co. KG Bicyclic heterocycles, medicaments comprising them, their use and process for their preparation
EA200901041A1 (en) 2007-02-06 2010-02-26 Бёрингер Ингельхайм Интернациональ Гмбх BICYCLIC HETEROCYCLES CONTAINING THESE COMPOUNDS MEDICINES, THEIR APPLICATION AND METHOD OF OBTAINING THEM
WO2009092052A2 (en) 2008-01-18 2009-07-23 Massachusetts Eye And Ear Infirmary Methods and compositions for treating polyps
TWI472339B (en) 2008-01-30 2015-02-11 Genentech Inc Composition comprising antibody that binds to domain ii of her2 and acidic variants thereof
MX2010008621A (en) 2008-02-07 2010-09-24 Boehringer Ingelheim Int Spirocyclic heterocycles, medicaments containing said compounds, use thereof and method for their production.
JP5739802B2 (en) 2008-05-13 2015-06-24 アストラゼネカ アクチボラグ 4- (3-Chloro-2-fluoroanilino) -7-methoxy-6-{[1- (N-methylcarbamoylmethyl) piperidin-4-yl] oxy} quinazoline fumarate
US8426430B2 (en) * 2008-06-30 2013-04-23 Hutchison Medipharma Enterprises Limited Quinazoline derivatives
CA2733153C (en) 2008-08-08 2016-11-08 Boehringer Ingelheim International Gmbh Cyclohexyloxy substituted heterocycles, pharmaceutical compositions containing these compounds and processes for preparing them
SG10201402742YA (en) 2009-03-20 2014-08-28 Genentech Inc Bispecific anti-her antibodies
RU2012124093A (en) 2009-11-12 2013-12-20 Дженентек, Инк. METHOD FOR INCREASING DENSITY OF DENDRITIC SPIKES
AR079984A1 (en) 2010-01-12 2012-03-07 Hoffmann La Roche TRICYCLIC HETEROCICLIC COMPOUNDS, COMPOSITIONS AND ITS USE IN THE TREATMENT OF DISEASES MEDIATED BY THE INHIBITION OF JAK1
RU2587619C2 (en) 2010-02-18 2016-06-20 Дженентек, Инк. Neuregulin antagonists and use thereof in treating malignant growth
BR112012023382A2 (en) 2010-03-17 2018-05-15 F Hoffmann La Roche Ag T imidazopyridine compounds, compositions and methods of use.
RU2012148699A (en) 2010-04-16 2014-05-27 Дженентек, Инк. FOXO3A AS A PROGNOSTIC BIOMARKER FOR PI3K / ACT KINASE PATH INHIBITOR EFFICIENCY
CA2808236A1 (en) 2010-08-31 2012-03-08 Genentech, Inc. Biomarkers and methods of treatment
MX2013003019A (en) 2010-09-15 2013-05-28 Hoffmann La Roche Azabenzothiazole compounds, compositions and methods of use.
CA2817785A1 (en) 2010-11-19 2012-05-24 Toby Blench Pyrazolopyridines and pyrazolopyridines and their use as tyk2 inhibitors
WO2012085176A1 (en) 2010-12-23 2012-06-28 F. Hoffmann-La Roche Ag Tricyclic pyrazinone compounds, compositions and methods of use thereof as janus kinase inhibitors
WO2013007765A1 (en) 2011-07-13 2013-01-17 F. Hoffmann-La Roche Ag Fused tricyclic compounds for use as inhibitors of janus kinases
WO2013007768A1 (en) 2011-07-13 2013-01-17 F. Hoffmann-La Roche Ag Tricyclic heterocyclic compounds, compositions and methods of use thereof as jak inhibitors
WO2013024011A1 (en) 2011-08-12 2013-02-21 F. Hoffmann-La Roche Ag Indazole compounds, compositions and methods of use
BR112014003431A2 (en) 2011-08-17 2017-06-13 Genentech Inc antibody, nucleic acid, host cell, method of producing an antibody, immunoconjugate, pharmaceutical formulation, pharmaceutical agent, use of the antibody, method of treating an individual who has cancer, and time-lapse method for tumor recurrence
CN103827115A (en) 2011-09-20 2014-05-28 弗·哈夫曼-拉罗切有限公司 Imidazopyridine compounds, compositions and methods of use
JP2015500638A (en) 2011-11-30 2015-01-08 ジェネンテック, インコーポレイテッド ERBB3 mutations in cancer
BR112014024017A8 (en) 2012-03-27 2017-07-25 Genentech Inc METHODS FOR TREATMENT OF A TYPE OF CANCER, FOR TREATMENT OF CARCINOMA, FOR SELECTING A THERAPY AND FOR QUANTIFICATION AND HER3 INHIBITORS
MX2015010791A (en) 2013-02-22 2015-11-26 Hoffmann La Roche Methods of treating cancer and preventing drug resistance.
US9925240B2 (en) 2013-03-06 2018-03-27 Genentech, Inc. Methods of treating and preventing cancer drug resistance
RU2015143517A (en) 2013-03-13 2017-04-19 Дженентек, Инк. Pyrazole-containing compounds and their use
RU2015139054A (en) 2013-03-14 2017-04-19 Дженентек, Инк. METHODS FOR TREATING CANCER AND PREVENTION OF DRUG RESISTANCE OF CANCER
EP2968540A2 (en) 2013-03-14 2016-01-20 Genentech, Inc. Combinations of a mek inhibitor compound with an her3/egfr inhibitor compound and methods of use
CA2905123A1 (en) 2013-03-15 2014-09-18 Genentech, Inc. Methods of treating cancer and preventing cancer drug resistance
RU2016112568A (en) 2013-09-05 2017-10-06 Дженентек, Инк. ANTIPROLIFERATIVE COMPOUNDS
WO2015049325A1 (en) 2013-10-03 2015-04-09 F. Hoffmann-La Roche Ag Therapeutic inhibitors of cdk8 and uses thereof
WO2015058132A2 (en) 2013-10-18 2015-04-23 Genentech, Inc. Anti-rspo antibodies and methods of use
HUE047699T2 (en) 2013-12-17 2020-05-28 Hoffmann La Roche Methods of treating cancers using pd-1 axis binding antagonists and taxanes
US20150190506A1 (en) 2013-12-17 2015-07-09 Genentech, Inc. Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists
JP2017516458A (en) 2014-03-24 2017-06-22 ジェネンテック, インコーポレイテッド Cancer treatment with c-met antagonist and correlation with HGF expression of c-met antagonist
CN106132439A (en) 2014-03-31 2016-11-16 豪夫迈·罗氏有限公司 Comprise antiangiogenic agent and OX40 combines the combination treatment of agonist
BR112016022658A2 (en) 2014-03-31 2017-10-17 Genentech Inc anti-ox40 antibodies and methods of use
WO2016036873A1 (en) 2014-09-05 2016-03-10 Genentech, Inc. Therapeutic compounds and uses thereof
EP3193866A1 (en) 2014-09-19 2017-07-26 Genentech, Inc. Use of cbp/ep300 and bet inhibitors for treatment of cancer
WO2016057924A1 (en) 2014-10-10 2016-04-14 Genentech, Inc. Pyrrolidine amide compounds as histone demethylase inhibitors
BR112017009151A2 (en) 2014-11-03 2018-03-06 Genentech, Inc. Assays for Detecting Immune T-Cell Subgroups and Methods of Using Them
SG11201703521UA (en) 2014-11-03 2017-05-30 Genentech Inc Methods and biomarkers for predicting efficacy and evaluation of an ox40 agonist treatment
KR20170072343A (en) 2014-11-06 2017-06-26 제넨테크, 인크. Combination therapy comprising ox40 binding agonists and tigit inhibitors
JP6639497B2 (en) 2014-11-10 2020-02-05 ジェネンテック, インコーポレイテッド Bromodomain inhibitors and uses thereof
MA40940A (en) 2014-11-10 2017-09-19 Constellation Pharmaceuticals Inc SUBSTITUTED PYRROLOPYRIDINES USED AS BROMODOMA INHIBITORS
MA40943A (en) 2014-11-10 2017-09-19 Constellation Pharmaceuticals Inc SUBSTITUTED PYRROLOPYRIDINES USED AS BROMODOMA INHIBITORS
MX2017006320A (en) 2014-11-17 2017-08-10 Genentech Inc Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists.
JP6771464B2 (en) 2014-11-27 2020-10-21 ジェネンテック, インコーポレイテッド 4,5,6,7-Tetrahydro-1H-pyrazolo [4,3-C] Pyridine-3-amine compound as CBP and / or EP300 inhibitor
SG11201704707PA (en) 2014-12-23 2017-07-28 Genentech Inc Compositions and methods for treating and diagnosing chemotherapy-resistant cancers
CN107208138A (en) 2014-12-30 2017-09-26 豪夫迈·罗氏有限公司 For cancer prognosis and the method and composition for the treatment of
WO2016112251A1 (en) 2015-01-09 2016-07-14 Genentech, Inc. 4,5-dihydroimidazole derivatives and their use as histone demethylase (kdm2b) inhibitors
CN107406414B (en) 2015-01-09 2022-04-19 基因泰克公司 (piperidin-3-yl) (naphthalen-2-yl) methanone derivatives as inhibitors of histone demethylase KDM2B for the treatment of cancer
WO2016112298A1 (en) 2015-01-09 2016-07-14 Genentech, Inc. Pyridazinone derivatives and their use in the treatment of cancer
WO2016123391A1 (en) 2015-01-29 2016-08-04 Genentech, Inc. Therapeutic compounds and uses thereof
EP3250552B1 (en) 2015-01-30 2019-03-27 Genentech, Inc. Therapeutic compounds and uses thereof
MA41598A (en) 2015-02-25 2018-01-02 Constellation Pharmaceuticals Inc PYRIDAZINE THERAPEUTIC COMPOUNDS AND THEIR USES
CN107709364A (en) 2015-04-07 2018-02-16 豪夫迈·罗氏有限公司 Antigen binding complex and application method with agonist activity
CA2983282A1 (en) 2015-05-12 2016-11-17 Genentech, Inc. Therapeutic and diagnostic methods for cancer
ES2789500T5 (en) 2015-05-29 2023-09-20 Hoffmann La Roche Therapeutic and diagnostic procedures for cancer
WO2016200836A1 (en) 2015-06-08 2016-12-15 Genentech, Inc. Methods of treating cancer using anti-ox40 antibodies
MX2017015937A (en) 2015-06-08 2018-12-11 Genentech Inc Methods of treating cancer using anti-ox40 antibodies and pd-1 axis binding antagonists.
WO2016205320A1 (en) 2015-06-17 2016-12-22 Genentech, Inc. Methods of treating locally advanced or metastatic breast cancers using pd-1 axis binding antagonists and taxanes
CA2996233C (en) 2015-08-26 2024-01-16 Fundacion Del Sector Publico Estatal Centro Nacional De Investigaciones Oncologicas Carlos Iii (F.S.P. Cnio) Condensed tricyclic compounds as protein kinase inhibitors
KR20230125094A (en) 2015-09-25 2023-08-28 제넨테크, 인크. Anti-tigit antibodies and methods of use
AU2016369528B2 (en) 2015-12-16 2021-04-22 Genentech, Inc. Process for the preparation of tricyclic PI3K inhibitor compounds and methods for using the same for the treatment of cancer
JP6949030B2 (en) 2016-01-08 2021-10-13 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト Treatment of CEA-Positive Cancer Using PD-1 Axial Binding Antagonists and Anti-CEA / Anti-CD3 Bispecific Antibodies
KR20180119632A (en) 2016-02-29 2018-11-02 제넨테크, 인크. Treatment and Diagnosis Methods for Cancer
US20170319688A1 (en) 2016-04-14 2017-11-09 Genentech, Inc. Anti-rspo3 antibodies and methods of use
JP2019518426A (en) 2016-04-15 2019-07-04 ジェネンテック, インコーポレイテッド Cancer diagnosis and treatment method
MX2018012492A (en) 2016-04-15 2019-06-06 Genentech Inc Methods for monitoring and treating cancer.
EP3443120A2 (en) 2016-04-15 2019-02-20 H. Hoffnabb-La Roche Ag Methods for monitoring and treating cancer
CN115028617A (en) 2016-05-24 2022-09-09 基因泰克公司 Heterocyclic inhibitors of CBP/EP300 and their use in the treatment of cancer
CN109476663B (en) 2016-05-24 2021-11-09 基因泰克公司 Pyrazolopyridine derivatives for the treatment of cancer
US20200129519A1 (en) 2016-06-08 2020-04-30 Genentech, Inc. Diagnostic and therapeutic methods for cancer
WO2018027204A1 (en) 2016-08-05 2018-02-08 Genentech, Inc. Multivalent and multiepitopic anitibodies having agonistic activity and methods of use
EP3497129A1 (en) 2016-08-08 2019-06-19 H. Hoffnabb-La Roche Ag Therapeutic and diagnostic methods for cancer
TWI775781B (en) 2016-10-06 2022-09-01 美商建南德克公司 Therapeutic and diagnostic methods for cancer
JP2019535250A (en) 2016-10-29 2019-12-12 ジェネンテック, インコーポレイテッド Anti-MIC antibody and method of use
KR20190134631A (en) 2017-03-01 2019-12-04 제넨테크, 인크. How to diagnose and treat cancer
JP2020516638A (en) 2017-04-13 2020-06-11 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト Interleukin 2 immunoconjugates, CD40 agonists, and optional PD-1 axis binding antagonists for use in a method of treating cancer
EP3679159A1 (en) 2017-09-08 2020-07-15 H. Hoffnabb-La Roche Ag Diagnostic and therapeutic methods for cancer
US11369608B2 (en) 2017-10-27 2022-06-28 University Of Virginia Patent Foundation Compounds and methods for regulating, limiting, or inhibiting AVIL expression
EP3707510B1 (en) 2017-11-06 2024-06-26 F. Hoffmann-La Roche AG Diagnostic and therapeutic methods for cancer
AU2019275404A1 (en) 2018-05-21 2020-12-03 Bruker Spatial Biology, Inc. Molecular gene signatures and methods of using same
SG11202012446UA (en) 2018-06-23 2021-01-28 Genentech Inc Methods of treating lung cancer with a pd-1 axis binding antagonist, a platinum agent, and a topoisomerase ii inhibitor
MX2021000558A (en) 2018-07-18 2021-04-13 Genentech Inc Methods of treating lung cancer with a pd-1 axis binding antagonist, an antimetabolite, and a platinum agent.
TW202024023A (en) 2018-09-03 2020-07-01 瑞士商赫孚孟拉羅股份公司 Therapeutic compounds and methods of use
MX2021003214A (en) 2018-09-19 2021-05-12 Genentech Inc Therapeutic and diagnostic methods for bladder cancer.
MX2021003213A (en) 2018-09-21 2021-05-12 Genentech Inc Diagnostic methods for triple-negative breast cancer.
EP3867646A1 (en) 2018-10-18 2021-08-25 F. Hoffmann-La Roche AG Diagnostic and therapeutic methods for sarcomatoid kidney cancer
WO2020163589A1 (en) 2019-02-08 2020-08-13 Genentech, Inc. Diagnostic and therapeutic methods for cancer
JP2022521773A (en) 2019-02-27 2022-04-12 ジェネンテック, インコーポレイテッド Dosing for treatment with anti-TIGIT antibody and anti-CD20 antibody or anti-CD38 antibody
CA3131268A1 (en) 2019-02-27 2020-09-03 Epiaxis Therapeutics Pty Ltd Methods and agents for assessing t-cell function and predicting response to therapy
WO2020223233A1 (en) 2019-04-30 2020-11-05 Genentech, Inc. Prognostic and therapeutic methods for colorectal cancer
KR20220004744A (en) 2019-05-03 2022-01-11 제넨테크, 인크. Methods of Treating Cancer Using Anti-PD-L1 Antibodies
CN112300279A (en) 2019-07-26 2021-02-02 上海复宏汉霖生物技术股份有限公司 Methods and compositions directed to anti-CD 73 antibodies and variants
MX2022002738A (en) 2019-09-04 2022-06-27 Genentech Inc Cd8 binding agents and uses thereof.
EP4048693A1 (en) 2019-09-27 2022-08-31 F. Hoffmann-La Roche AG Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
CN114728936A (en) 2019-10-29 2022-07-08 豪夫迈·罗氏有限公司 Bifunctional compounds for the treatment of cancer
MX2022005400A (en) 2019-11-06 2022-05-24 Genentech Inc Diagnostic and therapeutic methods for treatment of hematologic cancers.
KR20220101138A (en) 2019-11-13 2022-07-19 제넨테크, 인크. Therapeutic compounds and methods of use
US11845799B2 (en) 2019-12-13 2023-12-19 Genentech, Inc. Anti-Ly6G6D antibodies and methods of use
AU2020408562A1 (en) 2019-12-20 2022-06-23 Erasca, Inc. Tricyclic pyridones and pyrimidones
IL294800A (en) 2020-01-27 2022-09-01 Genentech Inc Methods for treatment of cancer with an anti-tigit antagonist antibody
WO2021194481A1 (en) 2020-03-24 2021-09-30 Genentech, Inc. Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
WO2021177980A1 (en) 2020-03-06 2021-09-10 Genentech, Inc. Combination therapy for cancer comprising pd-1 axis binding antagonist and il6 antagonist
EP4127724A1 (en) 2020-04-03 2023-02-08 Genentech, Inc. Therapeutic and diagnostic methods for cancer
CN115885050A (en) 2020-04-28 2023-03-31 基因泰克公司 Methods and compositions for non-small cell lung cancer immunotherapy
MX2022015877A (en) 2020-06-16 2023-01-24 Genentech Inc Methods and compositions for treating triple-negative breast cancer.
US20210395366A1 (en) 2020-06-18 2021-12-23 Genentech, Inc. Treatment with anti-tigit antibodies and pd-1 axis binding antagonists
US11787775B2 (en) 2020-07-24 2023-10-17 Genentech, Inc. Therapeutic compounds and methods of use
EP4189121A1 (en) 2020-08-03 2023-06-07 Genentech, Inc. Diagnostic and therapeutic methods for lymphoma
EP4196612A1 (en) 2020-08-12 2023-06-21 Genentech, Inc. Diagnostic and therapeutic methods for cancer
AU2021347232A1 (en) 2020-09-23 2023-04-27 Erasca, Inc. Tricyclic pyridones and pyrimidones
WO2022076462A1 (en) 2020-10-05 2022-04-14 Genentech, Inc. Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
WO2022133345A1 (en) 2020-12-18 2022-06-23 Erasca, Inc. Tricyclic pyridones and pyrimidones
WO2022171745A1 (en) 2021-02-12 2022-08-18 F. Hoffmann-La Roche Ag Bicyclic tetrahydroazepine derivatives for the treatment of cancer
TW202313633A (en) 2021-05-25 2023-04-01 美商伊瑞斯卡公司 Sulfur-containing heteroaromatic tricyclic kras inhibitors
WO2022266206A1 (en) 2021-06-16 2022-12-22 Erasca, Inc. Kras inhibitor conjugates
TW202321261A (en) 2021-08-10 2023-06-01 美商伊瑞斯卡公司 Selective kras inhibitors
TW202332429A (en) 2021-11-24 2023-08-16 美商建南德克公司 Therapeutic compounds and methods of use
WO2023097194A2 (en) 2021-11-24 2023-06-01 Genentech, Inc. Therapeutic compounds and methods of use
WO2023191816A1 (en) 2022-04-01 2023-10-05 Genentech, Inc. Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
WO2023219613A1 (en) 2022-05-11 2023-11-16 Genentech, Inc. Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
WO2023240058A2 (en) 2022-06-07 2023-12-14 Genentech, Inc. Prognostic and therapeutic methods for cancer
WO2024015897A1 (en) 2022-07-13 2024-01-18 Genentech, Inc. Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
TW202413433A (en) 2022-07-19 2024-04-01 美商建南德克公司 Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
WO2024033458A1 (en) 2022-08-11 2024-02-15 F. Hoffmann-La Roche Ag Bicyclic tetrahydroazepine derivatives
WO2024033388A1 (en) 2022-08-11 2024-02-15 F. Hoffmann-La Roche Ag Bicyclic tetrahydrothiazepine derivatives
WO2024033389A1 (en) 2022-08-11 2024-02-15 F. Hoffmann-La Roche Ag Bicyclic tetrahydrothiazepine derivatives
WO2024033457A1 (en) 2022-08-11 2024-02-15 F. Hoffmann-La Roche Ag Bicyclic tetrahydrothiazepine derivatives
WO2024085242A2 (en) 2022-10-21 2024-04-25 Kawasaki Institute Of Industrial Promotion Non-fouling or super stealth vesicle
WO2024091991A1 (en) 2022-10-25 2024-05-02 Genentech, Inc. Therapeutic and diagnostic methods for multiple myeloma

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5760041A (en) * 1996-02-05 1998-06-02 American Cyanamid Company 4-aminoquinazoline EGFR Inhibitors

Also Published As

Publication number Publication date
NO20002166L (en) 2000-06-28
AU1308799A (en) 1999-05-31
NO20002166D0 (en) 2000-04-27
PL340800A1 (en) 2001-02-26
ZA9810134B (en) 2000-05-05
BR9814116A (en) 2000-10-03
KR20010031813A (en) 2001-04-16
AR016415A1 (en) 2001-07-04
NZ503991A (en) 2001-11-30
IL135622A0 (en) 2001-05-20
JP2001522802A (en) 2001-11-20
CN1278176A (en) 2000-12-27
EP1039910A1 (en) 2000-10-04
HUP0004286A2 (en) 2001-11-28
WO1999024037A1 (en) 1999-05-20
CA2306155A1 (en) 1999-05-20

Similar Documents

Publication Publication Date Title
HUP0004286A3 (en) Use of quinazoline derivatives for producing pharmaceutical compositions for treating colonic polyps
HUP0103386A3 (en) Use of quinazoline derivatives for producing pharmaceutical compositions having jak 3-inhibitor effect
HU9800535D0 (en) Use of pyrimidine derivatives for producing pharmaceutical compositions for preventing tumor
HUP0002893A3 (en) Substituted quinazoline derivatives, process for producing them and pharmaceutical compositions containing them
HU9800291D0 (en) Use of amido-pirimidine derivatives for producing pharmaceutical compositions for inhibiting decrease of glucose-metabolismus
HUP9901243A3 (en) Quinazoline derivatives, preparation and use thereof, pharmaceutical compositions containing these compounds
IL147217A0 (en) New spirooxindole derivatives and pharmaceutical compositions containing the same for treatment of pain
HUS1400001I1 (en) Quinazoline derivatives, producing them and pharmaceutical compositions containing the compounds
HUP0003929A3 (en) Piperazine derivatives and their use for producing pharmaceutical compositions as anti-inflammatory agents and pharmaceutical compositions containing them
IL101243A0 (en) Pharmaceutical compositions for treatment of benign prostatic hyperplasia
HUP0204226A3 (en) Quinazoline derivatives, pharmaceutical compositions containing them, their use and process for the preparation of the compounds
ZA969248B (en) New aminoacid derivatives process for the manufacture thereof and pharmaceutical compositions containing thesse compounds
IL120141A (en) Substituted quinazoline derivatives process for their preparation and pharmaceutical compositions containing them
IL117957A0 (en) Pharmaceutical compositions for the treatment of impotence
EP0942742A4 (en) Therapeutic compositions for treatment of cancer
HUP0201187A3 (en) Use of ecteinascidin743 for producing pharmaceutical compositions suitable for treating cancer
HUP0000942A3 (en) Quinoline and quinazoline compounds pharmaceutical compositions containing them, process producing them and their use
HUP0100170A3 (en) N-benzyl-3-indenylacetamides derivatives and use of them for producing pharmaceutical compositions for treating neoplasia
HUP9901326A3 (en) Benzopyran derivatives having leukotriene-antagonistic action, pharmaceutical compositions containing these compounds, process for the preparation and use of these compounds and compositions
EP0938901A4 (en) Medicinal compositions for treating liver diseases
HUP0004331A3 (en) Use of phanquinone for producing pharmaceutical compositions for the treatment of alzheimer's disease and combined pharmaceutical compositions containing it
HUP0002249A3 (en) Use of pyrimidine and triazine derivatives for producing pharmaceutical compositions useful for treating cancer
IL121096A0 (en) Pharmaceutical compositions for the treatment of liver disease
IL121329A0 (en) A pharmaceutical composition for the treatment of cancer
HUP0003803A3 (en) Use of flunarizine for producing pharmaceutical compositions useful for the topical treating of glaucoma