SG11202001050PA - Antibodies that bind egfr and cmet - Google Patents
Antibodies that bind egfr and cmetInfo
- Publication number
- SG11202001050PA SG11202001050PA SG11202001050PA SG11202001050PA SG11202001050PA SG 11202001050P A SG11202001050P A SG 11202001050PA SG 11202001050P A SG11202001050P A SG 11202001050PA SG 11202001050P A SG11202001050P A SG 11202001050PA SG 11202001050P A SG11202001050P A SG 11202001050PA
- Authority
- SG
- Singapore
- Prior art keywords
- cmet
- antibodies
- bind egfr
- egfr
- bind
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/35—Valency
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/526—CH3 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17185572 | 2017-08-09 | ||
PCT/NL2018/050537 WO2019031965A1 (en) | 2017-08-09 | 2018-08-09 | Antibodies that bind egfr and cmet |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202001050PA true SG11202001050PA (en) | 2020-03-30 |
Family
ID=59579503
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202001050PA SG11202001050PA (en) | 2017-08-09 | 2018-08-09 | Antibodies that bind egfr and cmet |
Country Status (16)
Country | Link |
---|---|
US (2) | US11773170B2 (en) |
EP (1) | EP3665198A1 (en) |
JP (2) | JP2020530028A (en) |
KR (1) | KR20200042485A (en) |
CN (1) | CN111094351A (en) |
AU (2) | AU2018312816B2 (en) |
BR (1) | BR112020002695A2 (en) |
CA (1) | CA3072404A1 (en) |
EA (1) | EA202090215A1 (en) |
IL (1) | IL272461A (en) |
MA (1) | MA49846A (en) |
MX (1) | MX2020001432A (en) |
PH (1) | PH12020550055A1 (en) |
SG (1) | SG11202001050PA (en) |
TW (1) | TW201910354A (en) |
WO (1) | WO2019031965A1 (en) |
Families Citing this family (12)
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SI3365373T1 (en) | 2015-10-23 | 2021-08-31 | Merus N.V. | Binding molecules that inhibit cancer growth |
TWI782930B (en) | 2016-11-16 | 2022-11-11 | 美商再生元醫藥公司 | Anti-met antibodies, bispecific antigen binding molecules that bind met, and methods of use thereof |
WO2018182422A1 (en) | 2017-03-31 | 2018-10-04 | Merus N.V. | Erbb-2 and erbb3 binding bispecific antibodies for use in the treatment f cells that have an nrg1 fusion gene |
WO2019190327A2 (en) * | 2018-03-30 | 2019-10-03 | Merus N.V. | Multivalent antibody |
US11254736B2 (en) * | 2019-02-15 | 2022-02-22 | Integral Molecular, Inc. | Antibodies comprising a common light chain and uses thereof |
KR20220017909A (en) | 2019-05-09 | 2022-02-14 | 메뤼스 엔.페. | Variant domains for protein multimerization and isolation thereof |
CN114340684A (en) | 2019-09-16 | 2022-04-12 | 瑞泽恩制药公司 | Radiolabeled MET binding proteins for immunopet imaging |
CN112898427B (en) * | 2019-12-03 | 2023-06-30 | 同济大学苏州研究院 | anti-c-Met single-arm antibody and preparation method and application thereof |
CN117480180A (en) | 2021-07-14 | 2024-01-30 | 江苏恒瑞医药股份有限公司 | Antigen binding molecules that specifically bind HGFR and EGFR and medical uses thereof |
WO2023172133A1 (en) | 2022-03-07 | 2023-09-14 | Merus N.V. | Combination therapy including antibodies that bind egfr and cmet |
TW202346353A (en) | 2022-03-07 | 2023-12-01 | 荷蘭商美勒斯公司 | Treatment with an antibody that binds egfr and cmet |
WO2024002256A1 (en) * | 2022-06-29 | 2024-01-04 | Doma Biopharmaceutical (Suzhou) Co., Ltd. | Anti-egfr/met antibodies and uses thereof |
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2018
- 2018-08-09 SG SG11202001050PA patent/SG11202001050PA/en unknown
- 2018-08-09 EA EA202090215A patent/EA202090215A1/en unknown
- 2018-08-09 US US16/637,464 patent/US11773170B2/en active Active
- 2018-08-09 MA MA049846A patent/MA49846A/en unknown
- 2018-08-09 BR BR112020002695-6A patent/BR112020002695A2/en unknown
- 2018-08-09 WO PCT/NL2018/050537 patent/WO2019031965A1/en unknown
- 2018-08-09 KR KR1020207006947A patent/KR20200042485A/en not_active Application Discontinuation
- 2018-08-09 CA CA3072404A patent/CA3072404A1/en active Pending
- 2018-08-09 CN CN201880059748.5A patent/CN111094351A/en active Pending
- 2018-08-09 MX MX2020001432A patent/MX2020001432A/en unknown
- 2018-08-09 TW TW107127888A patent/TW201910354A/en unknown
- 2018-08-09 EP EP18766377.8A patent/EP3665198A1/en active Pending
- 2018-08-09 JP JP2020507522A patent/JP2020530028A/en active Pending
- 2018-08-09 AU AU2018312816A patent/AU2018312816B2/en active Active
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2020
- 2020-02-04 IL IL272461A patent/IL272461A/en unknown
- 2020-02-07 PH PH12020550055A patent/PH12020550055A1/en unknown
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2021
- 2021-05-06 AU AU2021202874A patent/AU2021202874A1/en active Pending
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2023
- 2023-08-09 US US18/446,795 patent/US20240174756A1/en active Pending
- 2023-12-20 JP JP2023214896A patent/JP2024029049A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
MA49846A (en) | 2020-06-17 |
BR112020002695A2 (en) | 2020-08-25 |
TW201910354A (en) | 2019-03-16 |
CN111094351A (en) | 2020-05-01 |
EA202090215A1 (en) | 2020-07-01 |
KR20200042485A (en) | 2020-04-23 |
JP2020530028A (en) | 2020-10-15 |
AU2018312816B2 (en) | 2021-05-27 |
WO2019031965A1 (en) | 2019-02-14 |
CA3072404A1 (en) | 2019-02-14 |
AU2021202874A1 (en) | 2021-06-03 |
PH12020550055A1 (en) | 2020-10-19 |
IL272461A (en) | 2020-03-31 |
US11773170B2 (en) | 2023-10-03 |
MX2020001432A (en) | 2020-03-20 |
JP2024029049A (en) | 2024-03-05 |
US20240174756A1 (en) | 2024-05-30 |
EP3665198A1 (en) | 2020-06-17 |
US20200247892A1 (en) | 2020-08-06 |
AU2018312816A1 (en) | 2020-02-27 |
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