SG10201809411PA - Methods of treating early breast cancer with trastuzumab-mcc-dm1 and pertuzumab - Google Patents
Methods of treating early breast cancer with trastuzumab-mcc-dm1 and pertuzumabInfo
- Publication number
- SG10201809411PA SG10201809411PA SG10201809411PA SG10201809411PA SG10201809411PA SG 10201809411P A SG10201809411P A SG 10201809411PA SG 10201809411P A SG10201809411P A SG 10201809411PA SG 10201809411P A SG10201809411P A SG 10201809411PA SG 10201809411P A SG10201809411P A SG 10201809411PA
- Authority
- SG
- Singapore
- Prior art keywords
- pertuzumab
- mcc
- methods
- trastuzumab
- breast cancer
- Prior art date
Links
- 206010006187 Breast cancer Diseases 0.000 title abstract 3
- 229960002087 pertuzumab Drugs 0.000 title abstract 3
- 208000026310 Breast neoplasm Diseases 0.000 title abstract 2
- 229960001612 trastuzumab emtansine Drugs 0.000 title abstract 2
- 101001012157 Homo sapiens Receptor tyrosine-protein kinase erbB-2 Proteins 0.000 abstract 1
- 208000005726 Inflammatory Breast Neoplasms Diseases 0.000 abstract 1
- 206010021980 Inflammatory carcinoma of the breast Diseases 0.000 abstract 1
- 102100030086 Receptor tyrosine-protein kinase erbB-2 Human genes 0.000 abstract 1
- 239000000611 antibody drug conjugate Substances 0.000 abstract 1
- 229940049595 antibody-drug conjugate Drugs 0.000 abstract 1
- 201000004653 inflammatory breast carcinoma Diseases 0.000 abstract 1
Classifications
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461984132P | 2014-04-25 | 2014-04-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201809411PA true SG10201809411PA (en) | 2018-11-29 |
Family
ID=53053128
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201809411PA SG10201809411PA (en) | 2014-04-25 | 2015-04-23 | Methods of treating early breast cancer with trastuzumab-mcc-dm1 and pertuzumab |
SG11201608912VA SG11201608912VA (en) | 2014-04-25 | 2015-04-23 | Methods of treating early breast cancer with trastuzumab-mcc-dm1 and pertuzumab |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201608912VA SG11201608912VA (en) | 2014-04-25 | 2015-04-23 | Methods of treating early breast cancer with trastuzumab-mcc-dm1 and pertuzumab |
Country Status (13)
Country | Link |
---|---|
US (1) | US20170035907A1 (zh) |
EP (2) | EP3581586A1 (zh) |
JP (2) | JP2017513901A (zh) |
KR (1) | KR20160141857A (zh) |
CN (1) | CN106163558A (zh) |
AU (2) | AU2015249633B2 (zh) |
BR (1) | BR112016024789A2 (zh) |
CA (1) | CA2946860A1 (zh) |
IL (1) | IL248487A0 (zh) |
MX (1) | MX2016014007A (zh) |
RU (2) | RU2725093C2 (zh) |
SG (2) | SG10201809411PA (zh) |
WO (1) | WO2015164665A1 (zh) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI472339B (zh) | 2008-01-30 | 2015-02-11 | Genentech Inc | 包含結合至her2結構域ii之抗體及其酸性變異體的組合物 |
BRPI0812682A2 (pt) | 2008-06-16 | 2010-06-22 | Genentech Inc | tratamento de cáncer de mama metastático |
US9808528B2 (en) | 2014-06-18 | 2017-11-07 | Mersana Therapeutics, Inc. | Protein-polymer-drug conjugates and methods of using same |
TWI695011B (zh) | 2014-06-18 | 2020-06-01 | 美商梅爾莎納醫療公司 | 抗her2表位之單株抗體及其使用之方法 |
LT3356411T (lt) | 2015-10-02 | 2021-09-10 | F. Hoffmann-La Roche Ag | Bispecifiniai antikūnai, specifiniai pd1 ir tim3 |
CN107446045A (zh) * | 2016-07-22 | 2017-12-08 | 北京天广实生物技术股份有限公司 | 一种抗her2的抗体、其药物组合物及用途 |
US10377833B2 (en) | 2016-07-22 | 2019-08-13 | Beijing Mabworks Biotech Co., Ltd. | Bispecific anti-HER2 antibody |
CN108210935B (zh) * | 2016-12-09 | 2023-08-18 | 凯惠科技发展(上海)有限公司 | 抗体药物偶联物、制备方法、中间体、药物组合物及应用 |
JP6914336B2 (ja) * | 2016-12-28 | 2021-08-04 | ジェネンテック, インコーポレイテッド | 進行したher2発現がんの治療 |
CR20190376A (es) | 2017-01-17 | 2019-11-20 | Genentech Inc | Formulaciones de anticuerpos de her2 subcutáneas |
HRP20240069T1 (hr) * | 2017-03-02 | 2024-03-29 | Genentech, Inc. | Adjuvantno liječenje her2-pozitivnog raka dojke |
KR20190121816A (ko) | 2017-04-03 | 2019-10-28 | 에프. 호프만-라 로슈 아게 | 항-pd-1 항체와 돌연변이 il-2 또는 il-15의 면역접합체 |
HUE060019T2 (hu) * | 2017-04-05 | 2023-01-28 | Hoffmann La Roche | Anti-LAG3 antitestek |
SG11201909154SA (en) | 2017-04-05 | 2019-10-30 | Hoffmann La Roche | Bispecific antibodies specifically binding to pd1 and lag3 |
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US4968603A (en) | 1986-12-31 | 1990-11-06 | The Regents Of The University Of California | Determination of status in neoplastic disease |
US5720937A (en) | 1988-01-12 | 1998-02-24 | Genentech, Inc. | In vivo tumor detection assay |
WO1989006692A1 (en) | 1988-01-12 | 1989-07-27 | Genentech, Inc. | Method of treating tumor cells by inhibiting growth factor receptor function |
ATE155813T1 (de) | 1989-05-19 | 1997-08-15 | Genentech Inc | Her2 extrazellulare domäne |
US5208020A (en) | 1989-10-25 | 1993-05-04 | Immunogen Inc. | Cytotoxic agents comprising maytansinoids and their therapeutic use |
WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
US6800738B1 (en) | 1991-06-14 | 2004-10-05 | Genentech, Inc. | Method for making humanized antibodies |
DK0590058T3 (da) | 1991-06-14 | 2004-03-29 | Genentech Inc | Humaniseret heregulin-antistof |
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-
2015
- 2015-04-23 SG SG10201809411PA patent/SG10201809411PA/en unknown
- 2015-04-23 RU RU2016146129A patent/RU2725093C2/ru active
- 2015-04-23 CA CA2946860A patent/CA2946860A1/en not_active Abandoned
- 2015-04-23 AU AU2015249633A patent/AU2015249633B2/en not_active Ceased
- 2015-04-23 JP JP2016564157A patent/JP2017513901A/ja active Pending
- 2015-04-23 MX MX2016014007A patent/MX2016014007A/es unknown
- 2015-04-23 EP EP19161510.3A patent/EP3581586A1/en not_active Withdrawn
- 2015-04-23 SG SG11201608912VA patent/SG11201608912VA/en unknown
- 2015-04-23 RU RU2020120593A patent/RU2020120593A/ru unknown
- 2015-04-23 EP EP15720875.2A patent/EP3134440A1/en not_active Withdrawn
- 2015-04-23 KR KR1020167032501A patent/KR20160141857A/ko not_active Application Discontinuation
- 2015-04-23 WO PCT/US2015/027388 patent/WO2015164665A1/en active Application Filing
- 2015-04-23 CN CN201580018961.8A patent/CN106163558A/zh active Pending
- 2015-04-23 BR BR112016024789A patent/BR112016024789A2/pt not_active Application Discontinuation
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2016
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- 2016-10-25 IL IL248487A patent/IL248487A0/en unknown
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2020
- 2020-06-03 JP JP2020097226A patent/JP2020172487A/ja active Pending
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2021
- 2021-01-08 AU AU2021200109A patent/AU2021200109A1/en not_active Abandoned
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US20170035907A1 (en) | 2017-02-09 |
RU2016146129A3 (zh) | 2018-12-18 |
IL248487A0 (en) | 2016-12-29 |
AU2021200109A1 (en) | 2021-03-18 |
AU2015249633A1 (en) | 2016-11-17 |
RU2020120593A (ru) | 2020-09-01 |
EP3134440A1 (en) | 2017-03-01 |
AU2015249633B2 (en) | 2020-10-15 |
MX2016014007A (es) | 2017-01-11 |
BR112016024789A2 (pt) | 2017-10-24 |
JP2017513901A (ja) | 2017-06-01 |
JP2020172487A (ja) | 2020-10-22 |
KR20160141857A (ko) | 2016-12-09 |
WO2015164665A1 (en) | 2015-10-29 |
RU2016146129A (ru) | 2018-05-25 |
SG11201608912VA (en) | 2016-11-29 |
RU2725093C2 (ru) | 2020-06-29 |
CN106163558A (zh) | 2016-11-23 |
EP3581586A1 (en) | 2019-12-18 |
CA2946860A1 (en) | 2015-10-29 |
AU2015249633A8 (en) | 2016-12-01 |
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