SE9904507D0 - New compounds - Google Patents

New compounds

Info

Publication number
SE9904507D0
SE9904507D0 SE9904507A SE9904507A SE9904507D0 SE 9904507 D0 SE9904507 D0 SE 9904507D0 SE 9904507 A SE9904507 A SE 9904507A SE 9904507 A SE9904507 A SE 9904507A SE 9904507 D0 SE9904507 D0 SE 9904507D0
Authority
SE
Sweden
Prior art keywords
amino
hydroxypropyl
methylphosphinic acid
acid
active compounds
Prior art date
Application number
SE9904507A
Other languages
English (en)
Inventor
Kosrat Amin
Thomas Elebring
Peter Guzzo
Thomas Olsson
Marianne Swanson
Sverker Von Unge
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9904507A priority Critical patent/SE9904507D0/sv
Publication of SE9904507D0 publication Critical patent/SE9904507D0/sv
Priority to UA2002064506A priority patent/UA73149C2/uk
Priority to TW089125146A priority patent/TWI225415B/zh
Priority to KR1020027007356A priority patent/KR100752010B1/ko
Priority to CZ20021984A priority patent/CZ20021984A3/cs
Priority to SK763-2002A priority patent/SK7632002A3/sk
Priority to RU2002113916/04A priority patent/RU2267495C2/ru
Priority to NZ519377A priority patent/NZ519377A/en
Priority to MXPA02005537A priority patent/MXPA02005537A/es
Priority to EEP200200287A priority patent/EE200200287A/xx
Priority to JP2001543088A priority patent/JP2003516346A/ja
Priority to PL00357115A priority patent/PL357115A1/xx
Priority to US09/786,220 priority patent/US6596711B1/en
Priority to AU22412/01A priority patent/AU780259B2/en
Priority to IL15009000A priority patent/IL150090A0/xx
Priority to CA002393510A priority patent/CA2393510A1/en
Priority to CNB008169063A priority patent/CN1200713C/zh
Priority to PCT/SE2000/002427 priority patent/WO2001041743A1/en
Priority to HU0300386A priority patent/HUP0300386A3/hu
Priority to BR0016291-4A priority patent/BR0016291A/pt
Priority to EP00986117A priority patent/EP1239843A1/en
Priority to ARP000106429A priority patent/AR033350A1/es
Priority to CO00093168A priority patent/CO5261538A1/es
Priority to ZA200204122A priority patent/ZA200204122B/xx
Priority to IS6409A priority patent/IS6409A/is
Priority to IL150090A priority patent/IL150090A/en
Priority to NO20022729A priority patent/NO20022729L/no
Priority to HK03105476A priority patent/HK1053066A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids R2P(=O)(OH); Thiophosphinic acids, i.e. R2P(=X)(XH) (X = S, Se)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/08—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids R2P(=O)(OH); Thiophosphinic acids, i.e. R2P(=X)(XH) (X = S, Se)
    • C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
SE9904507A 1999-12-09 1999-12-09 New compounds SE9904507D0 (sv)

Priority Applications (28)

Application Number Priority Date Filing Date Title
SE9904507A SE9904507D0 (sv) 1999-12-09 1999-12-09 New compounds
UA2002064506A UA73149C2 (en) 1999-12-09 2000-04-12 Aminopropylmethylphosphinic acids
TW089125146A TWI225415B (en) 1999-12-09 2000-11-27 New (aminopropyl)methylphosphinic acids
EP00986117A EP1239843A1 (en) 1999-12-09 2000-12-04 New (aminopropyl)methylphosphinic acids
US09/786,220 US6596711B1 (en) 1999-12-09 2000-12-04 (Aminopropyl)methylphosphinic acids
CNB008169063A CN1200713C (zh) 1999-12-09 2000-12-04 新的(氨基丙基)次膦酸
SK763-2002A SK7632002A3 (en) 1999-12-09 2000-12-04 New (aminopropyl)methylphosphinic acids
RU2002113916/04A RU2267495C2 (ru) 1999-12-09 2000-12-04 Новые (аминопропил)метилфосфиновые кислоты
NZ519377A NZ519377A (en) 1999-12-09 2000-12-04 (3-Amino-2-fluoropropyl)(methyl)phosphinic acids useful for treating gastro-oesphageal reflux disease
MXPA02005537A MXPA02005537A (es) 1999-12-09 2000-12-04 Nuevos acidos (aminopropil)metilfosfinicos.
EEP200200287A EE200200287A (et) 1999-12-09 2000-12-04 Uued (aminopropüül)metüülfosfiinhapped ning nendekasutamine
JP2001543088A JP2003516346A (ja) 1999-12-09 2000-12-04 新規な（アミノプロピル）メチルホスフィン酸
PL00357115A PL357115A1 (en) 1999-12-09 2000-12-04 New (aminopropyl)methylphosphinic acids
KR1020027007356A KR100752010B1 (ko) 1999-12-09 2000-12-04 신규 (아미노프로필)메틸포스핀산
AU22412/01A AU780259B2 (en) 1999-12-09 2000-12-04 New (aminopropyl)methylphosphinic acids
IL15009000A IL150090A0 (en) 1999-12-09 2000-12-04 New (aminopropyl)methylphosphinic acids
CA002393510A CA2393510A1 (en) 1999-12-09 2000-12-04 New (aminopropyl)methylphosphinic acids
CZ20021984A CZ20021984A3 (cs) 1999-12-09 2000-12-04 Nové (aminopropyl)methylfosfinové kyseliny
PCT/SE2000/002427 WO2001041743A1 (en) 1999-12-09 2000-12-04 New (aminopropyl)methylphosphinic acids
HU0300386A HUP0300386A3 (en) 1999-12-09 2000-12-04 New (aminopropyl) methylphosphinic acids
BR0016291-4A BR0016291A (pt) 1999-12-09 2000-12-04 Composto, uso do mesmo, métodos para a inibição das relaxações do esfìncter esofágico inferior transientes, para o tratamento da doença do refluxo gastroesofágico, da regurgitação em bebês, de nocicepção, êmese, dispepsia, ibs, soluços, adicção de cocaìna, dor, tosse, eructação, asma relacionada ou não com gord, e, formulação farmacêutica
ARP000106429A AR033350A1 (es) 1999-12-09 2000-12-05 Acidos (aminopropil) metilfosfinicos, su uso para la manufactura de medicamentos, formulacion farmaceutica, e intermediarios
CO00093168A CO5261538A1 (es) 1999-12-09 2000-12-06 Nuevos acidos (aminopropil) metilfosfinicos
ZA200204122A ZA200204122B (en) 1999-12-09 2002-05-23 New (aminopropyl)methylphosphinic acids.
IS6409A IS6409A (is) 1999-12-09 2002-06-06 Nýjar (amínóprópýl)metýlfosfínsýrur
IL150090A IL150090A (en) 1999-12-09 2002-06-06 Methylphosphinic (aminopropyl) acids
NO20022729A NO20022729L (no) 1999-12-09 2002-06-07 Nye (aminopropyl-)metylfosfinsyrer
HK03105476A HK1053066A1 (en) 1999-12-09 2003-07-29 New (aminopropyl) methylphosphinic acids.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9904507A SE9904507D0 (sv) 1999-12-09 1999-12-09 New compounds

Publications (1)

Publication Number Publication Date
SE9904507D0 true SE9904507D0 (sv) 1999-12-09

Family

ID=20418062

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9904507A SE9904507D0 (sv) 1999-12-09 1999-12-09 New compounds

Country Status (27)

Country Link
US (1) US6596711B1 (sv)
EP (1) EP1239843A1 (sv)
JP (1) JP2003516346A (sv)
KR (1) KR100752010B1 (sv)
CN (1) CN1200713C (sv)
AR (1) AR033350A1 (sv)
AU (1) AU780259B2 (sv)
BR (1) BR0016291A (sv)
CA (1) CA2393510A1 (sv)
CO (1) CO5261538A1 (sv)
CZ (1) CZ20021984A3 (sv)
EE (1) EE200200287A (sv)
HK (1) HK1053066A1 (sv)
HU (1) HUP0300386A3 (sv)
IL (2) IL150090A0 (sv)
IS (1) IS6409A (sv)
MX (1) MXPA02005537A (sv)
NO (1) NO20022729L (sv)
NZ (1) NZ519377A (sv)
PL (1) PL357115A1 (sv)
RU (1) RU2267495C2 (sv)
SE (1) SE9904507D0 (sv)
SK (1) SK7632002A3 (sv)
TW (1) TWI225415B (sv)
UA (1) UA73149C2 (sv)
WO (1) WO2001041743A1 (sv)
ZA (1) ZA200204122B (sv)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9904508D0 (sv) * 1999-12-09 1999-12-09 Astra Ab New compounds
US7319095B2 (en) * 1999-12-09 2008-01-15 Astrazeneca Ab Use of GABAB receptor agonists
TW200407110A (en) 2001-11-23 2004-05-16 Astrazeneca Ab New use for the treatment of gastroesophageal reflux disease
SE0201940D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination II
SE0201939D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination
DE10305463A1 (de) * 2003-02-04 2004-08-12 Schering Ag Enantiomerenreines (4S,8S)- und (4R,8R)-4-p-Nitrobenzyl-8-methyl-3,6,9-triza-3N,6N,9N-tricarboxymethyl-1,11-undecandisäure und deren Abkömmlinge, Verfahren zu deren Herstellung und Verwendung zur Herstellung pharmazeutischer Mittel
SE0401653D0 (sv) 2004-06-24 2004-06-24 Astrazeneca Ab New compounds
SE0402462D0 (sv) * 2004-10-08 2004-10-08 Astrazeneca Ab New process
CA2632021A1 (en) 2005-12-23 2007-06-28 Astrazeneca Ab Gaba-b receptor modulators
WO2007073298A1 (en) 2005-12-23 2007-06-28 Astrazeneca Ab Imidazole derivatives for the treatment of gastrointestinal disorders
EP2155762B1 (en) 2007-05-04 2011-10-12 AstraZeneca AB Process for the synthesis of alkyl phosphinic acids by initiation of an amine and an amineoxide
US20100317626A1 (en) * 2007-07-25 2010-12-16 Astrazeneca Ab The Use Of (3-Amino-2-Fluoropropyl) Phosphinic Acid For Treatment Of NERD
WO2009082344A1 (en) * 2007-12-21 2009-07-02 Astrazeneca Ab Novel process for making (2r)-(3-amino-2-fluoropropyl)phosphinic acid form a
WO2009082345A1 (en) * 2007-12-21 2009-07-02 Astrazeneca Ab Novel crystalline form b of (2r)-(3-amino-2-fluoropropyl)phosphinic acid
JP2011026260A (ja) * 2009-07-28 2011-02-10 Central Glass Co Ltd ３位に脱離基を有する２−フルオロプロピルアミン保護体または該アミンｎ−アルキル保護体
WO2011113904A1 (en) 2010-03-17 2011-09-22 INSERM (Institut National de la Santé et de la Recherche Médicale) Medicaments for the prevention and treatment of a disease associated with retinal ganglion cell degeneration

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH449046A (de) 1963-07-09 1967-12-31 Ciba Geigy Verfahren zur Herstellung neuer Aminosäuren
GB8425872D0 (en) 1984-10-12 1984-11-21 Ciba Geigy Ag Chemical compounds
WO1987004077A1 (en) 1986-01-03 1987-07-16 The University Of Melbourne Gastro-oesophageal reflux composition
GB8820266D0 (en) 1988-08-26 1988-09-28 Smith Kline French Lab Compounds
US5281747A (en) * 1989-05-13 1994-01-25 Ciba-Geigy Corporation Substituted aminoalkylphosphinic acids
US5567840A (en) * 1989-05-13 1996-10-22 Ciba-Geigy Corporation Substituted aminoalkylphosphinic acids
GB8911017D0 (en) * 1989-05-13 1989-06-28 Ciba Geigy Ag Substituted aminoalkylphosphinic acids
FR2663934B1 (fr) 1990-06-27 1994-06-03 Adir Nouveaux derives de l'acide 4 - amino butyrique, leur procede de preparation et les preparations pharmaceutiques qui les contiennent.
FR2722192A1 (fr) 1994-07-06 1996-01-12 Adir Nouveaux derives de l'acide 4-amino butyrique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
GB9420784D0 (en) 1994-10-14 1994-11-30 Glaxo Group Ltd Medicaments
SE9603408D0 (sv) 1996-09-18 1996-09-18 Astra Ab Medical use

Also Published As

Publication number Publication date
RU2002113916A (ru) 2004-01-10
AU2241201A (en) 2001-06-18
KR100752010B1 (ko) 2007-08-28
EE200200287A (et) 2003-08-15
BR0016291A (pt) 2002-08-13
NO20022729D0 (no) 2002-06-07
IS6409A (is) 2002-06-06
MXPA02005537A (es) 2004-09-10
EP1239843A1 (en) 2002-09-18
AU780259B2 (en) 2005-03-10
CZ20021984A3 (cs) 2002-11-13
US6596711B1 (en) 2003-07-22
KR20020060993A (ko) 2002-07-19
UA73149C2 (en) 2005-06-15
TWI225415B (en) 2004-12-21
PL357115A1 (en) 2004-07-12
SK7632002A3 (en) 2003-03-04
RU2267495C2 (ru) 2006-01-10
NZ519377A (en) 2003-11-28
HUP0300386A3 (en) 2005-08-29
WO2001041743A1 (en) 2001-06-14
CN1200713C (zh) 2005-05-11
JP2003516346A (ja) 2003-05-13
IL150090A (en) 2006-08-01
CO5261538A1 (es) 2003-03-31
IL150090A0 (en) 2002-12-01
HUP0300386A2 (hu) 2003-07-28
HK1053066A1 (en) 2003-10-10
ZA200204122B (en) 2003-10-29
NO20022729L (no) 2002-07-09
CN1413104A (zh) 2003-04-23
CA2393510A1 (en) 2001-06-14
AR033350A1 (es) 2003-12-17

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