NO995403L - Amidinderivater som inhibitorer av nitrogenoksydsyntase - Google Patents

Amidinderivater som inhibitorer av nitrogenoksydsyntase

Info

Publication number
NO995403L
NO995403L NO995403A NO995403A NO995403L NO 995403 L NO995403 L NO 995403L NO 995403 A NO995403 A NO 995403A NO 995403 A NO995403 A NO 995403A NO 995403 L NO995403 L NO 995403L
Authority
NO
Norway
Prior art keywords
nitric oxide
oxide synthase
inhibitors
amidine derivatives
compounds
Prior art date
Application number
NO995403A
Other languages
English (en)
Norwegian (no)
Other versions
NO995403D0 (no
Inventor
James Macdonald
James Matz
William Shakespeare
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of NO995403D0 publication Critical patent/NO995403D0/no
Publication of NO995403L publication Critical patent/NO995403L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO995403A 1997-05-05 1999-11-04 Amidinderivater som inhibitorer av nitrogenoksydsyntase NO995403L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9701681A SE9701681D0 (sv) 1997-05-05 1997-05-05 New compounds
PCT/SE1998/000785 WO1998050382A1 (en) 1997-05-05 1998-04-28 Amidine derivatives as inhibitors of nitric oxide synthase

Publications (2)

Publication Number Publication Date
NO995403D0 NO995403D0 (no) 1999-11-04
NO995403L true NO995403L (no) 2000-01-05

Family

ID=20406835

Family Applications (1)

Application Number Title Priority Date Filing Date
NO995403A NO995403L (no) 1997-05-05 1999-11-04 Amidinderivater som inhibitorer av nitrogenoksydsyntase

Country Status (25)

Country Link
US (1) US6489322B1 (sv)
EP (1) EP0983268B1 (sv)
JP (1) JP2001523262A (sv)
KR (1) KR20010012228A (sv)
CN (1) CN1255131A (sv)
AR (1) AR012601A1 (sv)
AT (1) ATE221065T1 (sv)
AU (1) AU734391B2 (sv)
BR (1) BR9809218A (sv)
CA (1) CA2288333A1 (sv)
DE (1) DE69806750T2 (sv)
EE (1) EE9900474A (sv)
HU (1) HUP0001873A3 (sv)
ID (1) ID22885A (sv)
IL (1) IL132678A0 (sv)
IS (1) IS5236A (sv)
MX (1) MXPA99009882A (sv)
NO (1) NO995403L (sv)
NZ (1) NZ500675A (sv)
PL (1) PL336853A1 (sv)
SE (1) SE9701681D0 (sv)
SK (1) SK140599A3 (sv)
TR (1) TR199902720T2 (sv)
WO (1) WO1998050382A1 (sv)
ZA (1) ZA983736B (sv)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI243164B (en) * 2001-02-13 2005-11-11 Aventis Pharma Gmbh Acylated indanyl amines and their use as pharmaceuticals
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
KR20070119750A (ko) * 2005-04-26 2007-12-20 가부시끼가이샤 도시바 백색 ｌｅｄ, 그것을 이용한 백라이트, 및 액정 표시 장치
JP2009501705A (ja) * 2005-07-05 2009-01-22 アストラゼネカ・アクチエボラーグ 新規化合物、その製造方法、中間体、医薬組成物、並びにアルツハイマー病、認知障害、統合失調症に伴う認識機能障害、肥満及びパーキンソン病のような５−ｈｔ６介在疾患の治療におけるそれらの使用
MY148644A (en) 2005-07-18 2013-05-15 Orion Corp New pharmaceutical compounds
ATE528306T1 (de) * 2006-11-02 2011-10-15 Piramal Life Sciences Ltd Benzoxazepin-verbindungen, ihre herstellung und verwendung
WO2008108445A1 (ja) 2007-03-07 2008-09-12 Takeda Pharmaceutical Company Limited ベンゾオキサゼピン誘導体およびその用途
WO2008144483A2 (en) * 2007-05-18 2008-11-27 Armgo Pharma, Inc. Agents for treating disorders involving modulation of ryanodine receptors
EP2432779A1 (en) * 2009-05-22 2012-03-28 Exelixis, Inc. Benzoxazepines based p13k/mt0r inhibitors against proliferative diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL110643A (en) 1993-08-12 1998-07-15 Astra Ab History of amidine, their preparation and the pharmaceutical preparations containing them
AU7705694A (en) 1993-10-04 1995-05-01 Glaxo Wellcome House Substituted urea and isothiourea derivatives as no synthase inhibitors
EP0724570B1 (en) 1993-10-21 1999-03-03 G.D. Searle & Co. Amidino derivatives useful as nitric oxide synthase inhibitors
ATE182889T1 (de) * 1994-05-07 1999-08-15 Astra Ab Bicyclische amidinderivate als no-synthetase inhibitoren
TW397812B (en) 1995-02-11 2000-07-11 Astra Ab Bicyclic isothiourea derivatives useful in therapy
SK281442B6 (sk) 1995-08-10 2001-03-12 Astra Aktiebolag Bicyklické amidínové deriváty, spôsob ich prípravy, farmaceutické kompozície s ich obsahom a ich použitie
TW458978B (en) * 1995-11-07 2001-10-11 Astra Ab Amidine and isothiourea derivatives as inhibitors of nitric oxide synthase

Also Published As

Publication number Publication date
EE9900474A (et) 2000-06-15
EP0983268A1 (en) 2000-03-08
WO1998050382A1 (en) 1998-11-12
HUP0001873A2 (hu) 2001-01-29
US6489322B1 (en) 2002-12-03
IS5236A (is) 1999-11-01
SK140599A3 (en) 2000-06-12
KR20010012228A (ko) 2001-02-15
AU734391B2 (en) 2001-06-14
MXPA99009882A (es) 2005-11-22
ZA983736B (en) 1998-11-05
AU7459898A (en) 1998-11-27
SE9701681D0 (sv) 1997-05-05
CN1255131A (zh) 2000-05-31
AR012601A1 (es) 2000-11-08
ATE221065T1 (de) 2002-08-15
ID22885A (id) 1999-12-16
NZ500675A (en) 2001-05-25
PL336853A1 (en) 2000-07-17
EP0983268B1 (en) 2002-07-24
BR9809218A (pt) 2000-06-27
NO995403D0 (no) 1999-11-04
DE69806750D1 (de) 2002-08-29
IL132678A0 (en) 2001-03-19
TR199902720T2 (xx) 2000-02-21
DE69806750T2 (de) 2003-03-06
CA2288333A1 (en) 1998-11-12
HUP0001873A3 (en) 2001-12-28
JP2001523262A (ja) 2001-11-20

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application