SE9604786D0 - New compounds - Google Patents

New compounds

Info

Publication number
SE9604786D0
SE9604786D0 SE9604786A SE9604786A SE9604786D0 SE 9604786 D0 SE9604786 D0 SE 9604786D0 SE 9604786 A SE9604786 A SE 9604786A SE 9604786 A SE9604786 A SE 9604786A SE 9604786 D0 SE9604786 D0 SE 9604786D0
Authority
SE
Sweden
Prior art keywords
new compounds
compounds
pain
chem
therapy
Prior art date
Application number
SE9604786A
Other languages
English (en)
Inventor
Edward Roberts
Benjamin Pelcman
Original Assignee
Astra Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharma Inc filed Critical Astra Pharma Inc
Priority to SE9604786A priority Critical patent/SE9604786D0/sv
Publication of SE9604786D0 publication Critical patent/SE9604786D0/sv
Priority to UA99074131A priority patent/UA54481C2/uk
Priority to CNB971808376A priority patent/CN1154635C/zh
Priority to KR1019997005586A priority patent/KR20000069600A/ko
Priority to CA002274117A priority patent/CA2274117A1/en
Priority to TR1999/01411T priority patent/TR199901411T2/xx
Priority to CNA2004100324204A priority patent/CN1539824A/zh
Priority to JP52867098A priority patent/JP2001507021A/ja
Priority to EP04002901A priority patent/EP1428821A1/en
Priority to SI9730659T priority patent/SI0946510T1/xx
Priority to PT97950539T priority patent/PT946510E/pt
Priority to BR9713785-5A priority patent/BR9713785A/pt
Priority to NZ336028A priority patent/NZ336028A/en
Priority to EEP199900261A priority patent/EE03966B1/xx
Priority to RU99115746/04A priority patent/RU2193030C2/ru
Priority to DE69729115T priority patent/DE69729115T2/de
Priority to SK763-99A priority patent/SK283300B6/sk
Priority to ZA9711049A priority patent/ZA9711049B/xx
Priority to AU53513/98A priority patent/AU738002B2/en
Priority to ES97950539T priority patent/ES2219783T3/es
Priority to PL97334370A priority patent/PL188945B1/pl
Priority to HU0000613A priority patent/HUP0000613A3/hu
Priority to EP97950539A priority patent/EP0946510B1/en
Priority to PCT/SE1997/002051 priority patent/WO1998028270A1/en
Priority to DK97950539T priority patent/DK0946510T3/da
Priority to IDW990536A priority patent/ID21662A/id
Priority to AT97950539T priority patent/ATE266638T1/de
Priority to IL13053697A priority patent/IL130536A0/xx
Priority to US09/029,468 priority patent/US6153626A/en
Priority to CZ992200A priority patent/CZ220099A3/cs
Priority to MYPI97006174A priority patent/MY132705A/en
Priority to ARP970106076A priority patent/AR010378A1/es
Priority to IS5078A priority patent/IS5078A/is
Priority to NO19993023A priority patent/NO313632B1/no
Priority to HK00102011A priority patent/HK1022910A1/xx
Priority to HK00103168A priority patent/HK1023996A1/xx
Priority to US09/645,565 priority patent/US6399635B1/en
Priority to US10/121,683 priority patent/US6710179B2/en
Priority to US10/628,309 priority patent/US6974825B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0446—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
SE9604786A 1996-12-20 1996-12-20 New compounds SE9604786D0 (sv)

Priority Applications (39)

Application Number Priority Date Filing Date Title
SE9604786A SE9604786D0 (sv) 1996-12-20 1996-12-20 New compounds
UA99074131A UA54481C2 (uk) 1996-12-20 1997-09-12 Сполуки з аналгезивною дією, спосіб їх отримання, фармакологічна композиція та діагностичний агент на їхній основі
HU0000613A HUP0000613A3 (en) 1996-12-20 1997-12-09 Piperidine derivatives with analgesic effect process for producing them and pharmaceutical compositions containing them
AU53513/98A AU738002B2 (en) 1996-12-20 1997-12-09 Novel compounds with analgesic effect
DE69729115T DE69729115T2 (de) 1996-12-20 1997-12-09 Verbindungen mit analgetischer wirkung
CA002274117A CA2274117A1 (en) 1996-12-20 1997-12-09 Novel compounds with analgesic effect
PL97334370A PL188945B1 (pl) 1996-12-20 1997-12-09 Heterocykliczne związki z atomem azotu, ich zastosowanie, środek diagnostyczny, środek farmaceutyczny, sposób wytwarzania heterocyklicznych związków z atomem azotu oraz nowe związki pośrednie
CNA2004100324204A CN1539824A (zh) 1996-12-20 1997-12-09 具有止痛作用的新化合物
JP52867098A JP2001507021A (ja) 1996-12-20 1997-12-09 鎮痛作用を有する新規な化合物
EP04002901A EP1428821A1 (en) 1996-12-20 1997-12-09 Piperidin-4-yl amines with analgesic effect
SI9730659T SI0946510T1 (en) 1996-12-20 1997-12-09 Novel compounds with analgesic effect
PT97950539T PT946510E (pt) 1996-12-20 1997-12-09 Novos compostos com efeito analgesico
BR9713785-5A BR9713785A (pt) 1996-12-20 1997-12-09 Composto, uso do mesmo, agente de diagnóstico, composição farmacêutica, e, processos para a preparação de um composto e para o tratamento da dor, de distúrbios gastrointestinais e de lesões na coluna vertebral.
NZ336028A NZ336028A (en) 1996-12-20 1997-12-09 Substituted 4-amino-piperidine and pyrrolidine derivatives having an analgesic effect
EEP199900261A EE03966B1 (et) 1996-12-20 1997-12-09 Valuvaigistava toimega ühendid ja nende valmistamise meetod
RU99115746/04A RU2193030C2 (ru) 1996-12-20 1997-12-09 Азотсодержащие гетероциклические соединения, способ их получения, фармацевтическая композиция на их основе и промежуточные вещества
KR1019997005586A KR20000069600A (ko) 1996-12-20 1997-12-09 진통 효과가 있는 신규 화합물
SK763-99A SK283300B6 (sk) 1996-12-20 1997-12-09 Piperidínové zlúčeniny s analgetickým účinkom, spôsob ich prípravy, medziprodukty na ich prípravu, ich použitie, diagnostické činidlo a farmaceutické kompozície s ich obsahom
ZA9711049A ZA9711049B (en) 1996-12-20 1997-12-09 Novel compounds with analgesic effect.
CNB971808376A CN1154635C (zh) 1996-12-20 1997-12-09 具有止痛作用的新化合物
ES97950539T ES2219783T3 (es) 1996-12-20 1997-12-09 Nuevos compuestos con efecto analgesico.
TR1999/01411T TR199901411T2 (xx) 1996-12-20 1997-12-09 Analjezik etkili yeni bile�imler.
CZ992200A CZ220099A3 (cs) 1996-12-20 1997-12-09 Nové sloučeniny s analgetickým účinkem
PCT/SE1997/002051 WO1998028270A1 (en) 1996-12-20 1997-12-09 Novel compounds with analgesic effect
EP97950539A EP0946510B1 (en) 1996-12-20 1997-12-09 Novel compounds with analgesic effect
DK97950539T DK0946510T3 (da) 1996-12-20 1997-12-09 Hidtil ukendte forbindelser med analgetisk virkning
IDW990536A ID21662A (id) 1996-12-20 1997-12-09 Senyawa-senyawa baru dengan efek analgesik
AT97950539T ATE266638T1 (de) 1996-12-20 1997-12-09 Verbindungen mit analgetischer wirkung
IL13053697A IL130536A0 (en) 1996-12-20 1997-12-09 Novel compounds with analgesic effect
US09/029,468 US6153626A (en) 1996-12-20 1997-12-09 Compounds with analgesic effect
ARP970106076A AR010378A1 (es) 1996-12-20 1997-12-19 Novedosos compuestos con efecto analgesico, uso de los mismos para la preparacion de un medicamento y como agente de diagnostico, composicion farmaceutica, proceso para la preparacion de dichos compuestos y compuestos intermediarios
MYPI97006174A MY132705A (en) 1996-12-20 1997-12-19 Novel compounds with analgesic effect
IS5078A IS5078A (is) 1996-12-20 1999-06-11 Ný efnasambönd með verkjadeyfandi áhrif
NO19993023A NO313632B1 (no) 1996-12-20 1999-06-18 Nye forbindelser med analgetisk effekt, farmasöytisk preparat inneholdende slike forbindelser, deres anvendelse, fremgangsmåtefor deres fremstilling og mellomprodukter
HK00102011A HK1022910A1 (en) 1996-12-20 2000-04-03 Novel compounds with analgesic effect.
HK00103168A HK1023996A1 (en) 1996-12-20 2000-05-29 Novel compounds with analgesic effect.
US09/645,565 US6399635B1 (en) 1996-12-20 2000-08-25 Compounds with analgesic effect
US10/121,683 US6710179B2 (en) 1996-12-20 2002-04-15 Compounds with analgesic effect
US10/628,309 US6974825B1 (en) 1996-12-20 2003-07-29 Compounds with analgesic effect

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9604786A SE9604786D0 (sv) 1996-12-20 1996-12-20 New compounds

Publications (1)

Publication Number Publication Date
SE9604786D0 true SE9604786D0 (sv) 1996-12-20

Family

ID=20405139

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9604786A SE9604786D0 (sv) 1996-12-20 1996-12-20 New compounds

Country Status (32)

Country Link
US (3) US6153626A (sv)
EP (2) EP1428821A1 (sv)
JP (1) JP2001507021A (sv)
KR (1) KR20000069600A (sv)
CN (2) CN1154635C (sv)
AR (1) AR010378A1 (sv)
AT (1) ATE266638T1 (sv)
AU (1) AU738002B2 (sv)
BR (1) BR9713785A (sv)
CA (1) CA2274117A1 (sv)
CZ (1) CZ220099A3 (sv)
DE (1) DE69729115T2 (sv)
DK (1) DK0946510T3 (sv)
EE (1) EE03966B1 (sv)
ES (1) ES2219783T3 (sv)
HK (2) HK1022910A1 (sv)
HU (1) HUP0000613A3 (sv)
ID (1) ID21662A (sv)
IL (1) IL130536A0 (sv)
IS (1) IS5078A (sv)
MY (1) MY132705A (sv)
NO (1) NO313632B1 (sv)
NZ (1) NZ336028A (sv)
PL (1) PL188945B1 (sv)
PT (1) PT946510E (sv)
RU (1) RU2193030C2 (sv)
SE (1) SE9604786D0 (sv)
SK (1) SK283300B6 (sv)
TR (1) TR199901411T2 (sv)
UA (1) UA54481C2 (sv)
WO (1) WO1998028270A1 (sv)
ZA (1) ZA9711049B (sv)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9504661D0 (sv) 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
SE9604786D0 (sv) * 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
US6974825B1 (en) 1996-12-20 2005-12-13 Astrazeneca Canada Inc. Compounds with analgesic effect
TW548271B (en) * 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
DK1049676T3 (da) * 1997-12-24 2006-01-16 Ortho Mcneil Pharm Inc 4-[Aryl(piperidin-4-yl)]aminobenzamider, som binder til delta-opioidreceptoren
AU2003220725B2 (en) * 1997-12-24 2006-06-01 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(piperidin-4-yl)] aminobenzamides which bind to the delta-opioid receptor
US6900228B1 (en) 1998-03-10 2005-05-31 Research Triangle Institute Opiate compounds, methods of making and methods of use
EP1512683B1 (en) * 1998-03-10 2011-08-31 Research Triangle Institute Novel opiate compounds, methods of making and methods of use
US6436959B1 (en) 1998-12-23 2002-08-20 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(piperidin-4-yl)]aminobenzamides
SE9904675D0 (sv) * 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE9904673D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE9904674D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
US6306876B1 (en) 1999-12-22 2001-10-23 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(8-azabicyclo[3.2.1]octan-3-yl)]aminobenzoic acid derivatives
WO2001060796A1 (en) 2000-02-18 2001-08-23 Meiji Seika Kaisha, Ltd. PHENOXYALKYLAMINE DERIVATIVES USEFUL AS OPIOID δ RECEPTOR AGONISTS
BR0108965A (pt) 2000-03-03 2002-11-26 Ortho Mcneil Pharm Inc Derivados de 3-(diarilmetileno)-8-azabiciclo[3,2,1]octano
US6790854B2 (en) 2000-03-24 2004-09-14 Meiji Seika Kaisha, Ltd. Diphenylalkylamine derivatives useful as opioid receptor agonists
SE0001209D0 (sv) 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
WO2002048122A2 (en) * 2000-12-14 2002-06-20 Ortho-Mcneil Pharmaceutical, Inc. Benzamidine derivatives
JP2004515539A (ja) * 2000-12-15 2004-05-27 アストラゼネカ・アクチエボラーグ ジアリール−４−アミノ−ピペリジニル化合物の新しい調製方法
SE0101773D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101769D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101771D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101770D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
PT1395567E (pt) 2001-05-18 2009-03-26 Astrazeneca Ab Derivados de 4(fenil-piperazinil-metil)benzamida e sua utilização para o tratamento da ansiedade da dor ou de distúrbios gastrointestinais
IL161348A0 (en) 2001-10-15 2004-09-27 Janssen Pharmaceutica Nv Novel substituted 4-phenyl-4-[1h-imidazol-2-yl]piperidine derivatives and their use as selective non-peptide delta opioid agonists
PL212089B1 (pl) * 2002-03-13 2012-08-31 Janssen Pharmaceutica Nv Związki heterocykliczne jako inhibitory deacetylazy histonowej, kompozycja farmaceutyczna je zawierająca, ich zastosowanie, sposób wytwarzania, sposób wykrywania lub identyfikacji HDAC oraz kompozycja
WO2003099773A1 (en) 2002-05-24 2003-12-04 Millennium Pharmaceuticals, Inc. Ccr9 inhibitors and methods of use thereof
SE0203302D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203300D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203303D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
US7741519B2 (en) 2007-04-23 2010-06-22 Chemocentryx, Inc. Bis-aryl sulfonamides
US7420055B2 (en) 2002-11-18 2008-09-02 Chemocentryx, Inc. Aryl sulfonamides
US7227035B2 (en) 2002-11-18 2007-06-05 Chemocentryx Bis-aryl sulfonamides
CN101077867B (zh) 2002-11-18 2012-10-10 坎莫森特里克斯公司 芳基磺酰胺
US7589103B2 (en) 2003-06-27 2009-09-15 Janssen Pharmaceutica N.V. Tricyclic-bridged piperidinylidene derivatives as 8-opioid modulators
EP1737853A1 (en) 2004-02-03 2007-01-03 Janssen Pharmaceutica N.V. 3-(diheteroarylmethylene)-8-azabicyclo¬3.2.1|octane and 3-((aryl)(heteroaryl)methylene)-8-azabicyclo¬3.2.1|octane derivatives
KR101234421B1 (ko) 2004-08-02 2013-02-18 아스트라제네카 아베 디아릴메틸 피페라진 유도체, 이의 제조 방법 및 용도
WO2007030089A1 (en) * 2004-08-05 2007-03-15 Janssen Pharmaceutica N.V. Tricyclic delta- opioid modulators
US7589104B2 (en) * 2004-12-22 2009-09-15 Janssen Pharmaceutica Nv Tricyclic-bridged piperidinyline derivatives as §-opioid modulators
CN101115751A (zh) * 2004-12-22 2008-01-30 詹森药业有限公司 三环δ-阿片样物质调节剂
KR20070092286A (ko) * 2004-12-22 2007-09-12 얀센 파마슈티카 엔.브이. 트리사이클릭 델타-오피오이드 조절제
CN101128460A (zh) * 2005-01-06 2008-02-20 詹森药业有限公司 三环的δ-阿片样物质调节剂
TWI410406B (zh) 2005-05-13 2013-10-01 Otsuka Pharma Co Ltd 吡咯烷化合物
JP2008543866A (ja) * 2005-06-16 2008-12-04 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 三環式オピオイドモジュレーター
JP5219465B2 (ja) * 2006-11-10 2013-06-26 大塚製薬株式会社 医薬

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091096A (en) * 1976-03-19 1978-05-23 Eli Lilly And Company Dinitroanilines for the control of phytopathogens
EG12406A (en) * 1976-08-12 1979-03-31 Janssen Pharmaceutica Nv Process for preparing of novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides
SE441448B (sv) * 1977-05-23 1985-10-07 Pfizer Sett att framstella hexahydro-gamma-karbolinforeningar
DE3200304A1 (de) * 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
DE3563964D1 (en) * 1984-10-16 1988-09-01 Synthelabo Piperidine derivatives, their preparation and their therapeutical application
YU150489A (sh) 1989-08-10 1992-12-21 W.L. Gore & Co. Gmbh. Uređaj za ispitivanje odevnih predmeta na nepromočivost
KR940003491B1 (ko) 1989-08-10 1994-04-23 리히터 게데온 베기에스제티 기아르 알.티 4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물
GB9202238D0 (en) * 1992-02-03 1992-03-18 Wellcome Found Compounds
US5854245A (en) * 1996-06-28 1998-12-29 Merck & Co., Inc. Fibrinogen receptor antagonists
TW548271B (en) * 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
SE9604786D0 (sv) 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
DK1049676T3 (da) * 1997-12-24 2006-01-16 Ortho Mcneil Pharm Inc 4-[Aryl(piperidin-4-yl)]aminobenzamider, som binder til delta-opioidreceptoren
EP1512683B1 (en) 1998-03-10 2011-08-31 Research Triangle Institute Novel opiate compounds, methods of making and methods of use
US6436959B1 (en) 1998-12-23 2002-08-20 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(piperidin-4-yl)]aminobenzamides

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US6153626A (en) 2000-11-28
PL334370A1 (en) 2000-02-28
HK1023996A1 (en) 2000-09-29
US6399635B1 (en) 2002-06-04
CA2274117A1 (en) 1998-07-02
US6710179B2 (en) 2004-03-23
EP0946510A1 (en) 1999-10-06
CZ220099A3 (cs) 1999-11-17
BR9713785A (pt) 2000-02-08
AR010378A1 (es) 2000-06-07
AU738002B2 (en) 2001-09-06
ATE266638T1 (de) 2004-05-15
WO1998028270A1 (en) 1998-07-02
IL130536A0 (en) 2000-06-01
ID21662A (id) 1999-07-08
EP0946510B1 (en) 2004-05-12
ZA9711049B (en) 1998-06-22
CN1539824A (zh) 2004-10-27
RU2193030C2 (ru) 2002-11-20
CN1154635C (zh) 2004-06-23
EE9900261A (et) 2000-02-15
EP1428821A8 (en) 2005-01-26
JP2001507021A (ja) 2001-05-29
NO993023D0 (no) 1999-06-18
SK283300B6 (sk) 2003-05-02
PT946510E (pt) 2004-08-31
PL188945B1 (pl) 2005-05-31
DE69729115D1 (de) 2004-06-17
HUP0000613A3 (en) 2002-10-28
MY132705A (en) 2007-10-31
TR199901411T2 (xx) 1999-09-21
HK1022910A1 (en) 2000-08-25
HUP0000613A2 (hu) 2000-09-28
AU5351398A (en) 1998-07-17
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UA54481C2 (uk) 2003-03-17
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US20030055045A1 (en) 2003-03-20
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ES2219783T3 (es) 2004-12-01

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