SE8702120D0 - 1-(hydroxystyryl)-5h-2,3-benzodiazepine derivatives, process for the preparation thereof and pharmaceutical compositions containing the same - Google Patents

1-(hydroxystyryl)-5h-2,3-benzodiazepine derivatives, process for the preparation thereof and pharmaceutical compositions containing the same

Info

Publication number
SE8702120D0
SE8702120D0 SE8702120A SE8702120A SE8702120D0 SE 8702120 D0 SE8702120 D0 SE 8702120D0 SE 8702120 A SE8702120 A SE 8702120A SE 8702120 A SE8702120 A SE 8702120A SE 8702120 D0 SE8702120 D0 SE 8702120D0
Authority
SE
Sweden
Prior art keywords
hydroxystyryl
preparation
pharmaceutical compositions
compositions containing
same
Prior art date
Application number
SE8702120A
Other languages
English (en)
Other versions
SE8702120L (sv
SE468560B (sv
Inventor
T Lang
J Korosi
G Rabloczky
T Hamori
M Kuhar
I Polgari
I Elekes
G Zolyomi
K Heltai
J Sarossy
Z Lang
I Moravcsik
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of SE8702120D0 publication Critical patent/SE8702120D0/sv
Publication of SE8702120L publication Critical patent/SE8702120L/sv
Publication of SE468560B publication Critical patent/SE468560B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE8702120A 1986-05-21 1987-05-21 1-(hydroxistyryl)-5h-2,3-bensodiazepinderivat, foerfarande foer deras framstaellning samt farmaceutiska kompositioner innehaallande desamma SE468560B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU862140A HU195788B (en) 1986-05-21 1986-05-21 Process for producing 1-/hydroxy-stiryl/-5h-2,3-benzobiazepines and pharmaceutical compositions containing them

Publications (3)

Publication Number Publication Date
SE8702120D0 true SE8702120D0 (sv) 1987-05-21
SE8702120L SE8702120L (sv) 1987-11-22
SE468560B SE468560B (sv) 1993-02-08

Family

ID=10957976

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8702120A SE468560B (sv) 1986-05-21 1987-05-21 1-(hydroxistyryl)-5h-2,3-bensodiazepinderivat, foerfarande foer deras framstaellning samt farmaceutiska kompositioner innehaallande desamma

Country Status (24)

Country Link
US (1) US4840948A (sv)
JP (1) JPS6322082A (sv)
AT (1) AT395009B (sv)
BE (1) BE1000573A4 (sv)
BG (1) BG46003A3 (sv)
CA (1) CA1280748C (sv)
CH (1) CH671226A5 (sv)
CS (1) CS262690B2 (sv)
DD (1) DD268943A5 (sv)
DE (1) DE3717080C2 (sv)
DK (1) DK258187A (sv)
ES (1) ES2005582A6 (sv)
FI (1) FI91964C (sv)
FR (1) FR2599034B1 (sv)
GB (1) GB2190677B (sv)
HU (1) HU195788B (sv)
IL (1) IL82613A (sv)
IT (1) IT1205665B (sv)
NL (1) NL8701213A (sv)
PL (1) PL147687B1 (sv)
PT (1) PT84923B (sv)
SE (1) SE468560B (sv)
SU (1) SU1503681A3 (sv)
YU (1) YU46675B (sv)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380721A (en) * 1990-09-10 1995-01-10 Sterling Winthrop Inc. Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents
HU224435B1 (hu) * 1995-02-09 2005-10-28 EGIS Gyógyszergyár Rt. Benzodiazepin-származékok, eljárás előállításukra, alkalmazásukra és ezeket tartalmazó gyógyászati készítmények
SK283859B6 (sk) * 1995-02-09 2004-03-02 EGIS Gyógyszergyár Rt. 1-[2'-(Substituovaný)vinyl]-5H-2,3-benzodiazepínové deriváty, spôsob ich prípravy a medziprodukty na ich prípravu, liečivá ich obsahujúce a ich použitie
EP0726256A1 (en) * 1995-02-09 1996-08-14 Egis Gyogyszergyar Rt. 1-Arylvinyl-3,4-dihydro-5H-2,3-benzodiazepine derivatives useful for the treatment of central nervous system disorders
ES2111493B1 (es) * 1996-02-08 1999-08-01 Egyt Gyogyszervegyeszeti Gyar Derivados de 1-(2- (vinilo substituido ) ) -5h-2,3-benzo-diazepina, procedimiento para su preparacion, composiciones farmaceuticas que los contienen y utilizaciones correspondientes.
HU227128B1 (en) * 1999-07-07 2010-07-28 Egyt Gyogyszervegyeszeti Gyar New 2,3-benzodiazepine derivatives
US6638928B1 (en) 2002-12-03 2003-10-28 Vela Pharmaceuticals, Inc. Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines
US6864251B2 (en) * 2002-12-03 2005-03-08 Vela Pharmaceuticals, Inc. Treatment of LTB4-mediated inflammatory disorders with optically-pure (R)-2,3-benzodiazepines
US7745431B2 (en) * 2002-12-03 2010-06-29 Vela Acquisition Corporation Pharmaceutical composition of 1-(3,4-dimethoxyphenyl)-4-methyl-5-ethyl-7-methoxy-8-hydroxy-5H-2,3-benzodiazepine and uses thereof
US7022700B2 (en) * 2002-12-03 2006-04-04 Vela Pharmaceuticals, Inc. Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines
MXPA05005893A (es) * 2002-12-03 2006-02-08 Vela Pharmaceuticals Inc Composicion farmaceutica de 1-(3-hidroxi -4-metoxifenil) -4-metil-5 -etil-7, 8-dimetoxi- 5h-2, 3-benzodiazepina y usos de la misma.
US20040224943A1 (en) * 2003-02-19 2004-11-11 Leventer Steven M. Method of lowering body temperature with (R) - 2,3-benzodiazepines
US20040162284A1 (en) * 2003-02-19 2004-08-19 Harris Herbert W. Method of lowering body temperature with (S) tofisopam
HUP0302449A3 (en) * 2003-08-04 2005-06-28 Egis Gyogyszergyar Nyilvanosan 8-chloro-2,3-benzodiazepine derivatives, pharmaceutical compositions containing them and process for producing them

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK118660B (da) * 1966-12-09 1970-09-21 Egyt Gyogyszervegyeszeti Gyar Analogifremgangsmåde til fremstilling af 1-(3',4'-dimethoxyphenyl)-3-methyl-4-ethyl-6,7-dimethoxy-isoquinolin-N-imid.
HU179018B (en) * 1978-10-19 1982-08-28 Gyogyszerkutato Intezet Process for producing new 5h-2,3-benzodiazepine derivatives
HU191698B (en) * 1984-07-27 1987-03-30 Gyogyszerkutato Intezet Process for producing new 1-aryl-5h-2beta-benzodiazepines

Also Published As

Publication number Publication date
HUT44521A (en) 1988-03-28
PT84923A (en) 1987-06-01
IL82613A (en) 1991-03-10
PL265812A1 (en) 1988-05-12
FI91964B (sv) 1994-05-31
CS262690B2 (en) 1989-03-14
NL8701213A (nl) 1987-12-16
ATA130287A (de) 1992-01-15
CA1280748C (en) 1991-02-26
PT84923B (pt) 1990-02-08
DD268943A5 (de) 1989-06-14
FR2599034B1 (fr) 1989-06-09
GB2190677A (en) 1987-11-25
CS369087A2 (en) 1988-08-16
BG46003A3 (en) 1989-09-15
SU1503681A3 (ru) 1989-08-23
CH671226A5 (sv) 1989-08-15
YU90687A (en) 1988-08-31
ES2005582A6 (es) 1989-03-16
HU195788B (en) 1988-07-28
US4840948A (en) 1989-06-20
PL147687B1 (en) 1989-07-31
FR2599034A1 (fr) 1987-11-27
FI91964C (sv) 1994-09-12
DK258187D0 (da) 1987-05-21
AT395009B (de) 1992-08-25
SE8702120L (sv) 1987-11-22
IT1205665B (it) 1989-03-31
DE3717080A1 (de) 1987-11-26
GB2190677B (en) 1990-01-10
DK258187A (da) 1987-11-22
FI872255A0 (sv) 1987-05-21
BE1000573A4 (fr) 1989-02-07
IL82613A0 (en) 1987-11-30
YU46675B (sh) 1994-01-20
DE3717080C2 (de) 1996-02-08
GB8712005D0 (en) 1987-06-24
IT8720619A0 (it) 1987-05-21
FI872255A (sv) 1987-11-22
JPS6322082A (ja) 1988-01-29
SE468560B (sv) 1993-02-08

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