SE7705947L - PROSTAGLAND PRECURSORS - Google Patents
PROSTAGLAND PRECURSORSInfo
- Publication number
- SE7705947L SE7705947L SE7705947A SE7705947A SE7705947L SE 7705947 L SE7705947 L SE 7705947L SE 7705947 A SE7705947 A SE 7705947A SE 7705947 A SE7705947 A SE 7705947A SE 7705947 L SE7705947 L SE 7705947L
- Authority
- SE
- Sweden
- Prior art keywords
- alpha
- tetranor
- thienyl
- oxo
- trans
- Prior art date
Links
- 239000002243 precursor Substances 0.000 title 1
- 125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 2
- YCXVDEMHEKQQCI-UHFFFAOYSA-N chloro-dimethyl-propan-2-ylsilane Chemical compound CC(C)[Si](C)(C)Cl YCXVDEMHEKQQCI-UHFFFAOYSA-N 0.000 abstract 1
- -1 dimethylisopropylsilyloxy Chemical group 0.000 abstract 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4056—Esters of arylalkanephosphonic acids
- C07F9/4059—Compounds containing the structure (RY)2P(=X)-(CH2)n-C(=O)-(CH2)m-Ar, (X, Y = O, S, Se; n>=1, m>=0)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
- C07F9/655345—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B63—SHIPS OR OTHER WATERBORNE VESSELS; RELATED EQUIPMENT
- B63B—SHIPS OR OTHER WATERBORNE VESSELS; EQUIPMENT FOR SHIPPING
- B63B2211/00—Applications
- B63B2211/02—Oceanography
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Crystallography & Structural Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Compounds Of Unknown Constitution (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
1446341 Silylated prostaglandins PFIZER Inc 13 July 1973 [13 July 1972] 31217/73 Heading C3S [Also in Division C2] 11α,15α - Bis - (dimethylisopropylsilyloxy)- 9 - oxo - 16 - (2 - thienyl) - 17,18,19,20 - tetranor - trans - 13 - prostenoic acid is prepared by hydrogenating 11α,15α - bis - (dimethylisopropylsilyloxy) - 9 - oxo - 16 - (2 - thienyl)- 17,18,19,20 - tetranor - cis - 5, trans - 13- prostadienoic acid, obtained by reacting dimethylisopropyl chlorosilane with 11α,15α- dihydroxy - 9 - oxo - 16 - (2 - thienyl) - 17,18, 19,20 - tetranor - cis - 5 trans - 13 - prostadienoic acid.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27122072A | 1972-07-13 | 1972-07-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
SE7705947L true SE7705947L (en) | 1977-05-20 |
Family
ID=23034697
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7705946A SE7705946L (en) | 1972-07-13 | 1977-05-20 | KETOPHOSPHONATES |
SE7705947A SE7705947L (en) | 1972-07-13 | 1977-05-20 | PROSTAGLAND PRECURSORS |
SE7705945A SE7705945L (en) | 1972-07-13 | 1977-05-20 | CYCLOPENTAN DERIVATIVES |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7705946A SE7705946L (en) | 1972-07-13 | 1977-05-20 | KETOPHOSPHONATES |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7705945A SE7705945L (en) | 1972-07-13 | 1977-05-20 | CYCLOPENTAN DERIVATIVES |
Country Status (25)
Country | Link |
---|---|
JP (4) | JPS5241257B2 (en) |
AR (2) | AR209064A1 (en) |
AT (1) | AT367033B (en) |
BE (1) | BE802231A (en) |
CA (1) | CA1041495A (en) |
CH (1) | CH593254A5 (en) |
CS (1) | CS201027B2 (en) |
DD (2) | DD109210A5 (en) |
DE (1) | DE2334945A1 (en) |
ES (4) | ES416865A1 (en) |
FI (1) | FI57583C (en) |
FR (1) | FR2192834B1 (en) |
GB (1) | GB1446341A (en) |
HU (4) | HU172058B (en) |
IE (1) | IE37909B1 (en) |
IL (2) | IL42691A (en) |
IN (1) | IN138789B (en) |
LU (1) | LU68015A1 (en) |
NL (1) | NL7309792A (en) |
NO (2) | NO143741C (en) |
PH (1) | PH11461A (en) |
SE (3) | SE7705946L (en) |
SU (4) | SU644384A3 (en) |
YU (1) | YU187773A (en) |
ZA (1) | ZA734769B (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1386146A (en) * | 1972-05-03 | 1975-03-05 | Ici Ltd | Cyclopentane derivatives |
DE2416193C2 (en) | 1974-04-03 | 1985-08-14 | Hoechst Ag, 6230 Frankfurt | Prostaglandin analogs, processes for their preparation and their use as cytoprotective agents |
DE2463432C2 (en) * | 1974-04-03 | 1987-06-19 | Hoechst Ag, 6230 Frankfurt, De | |
ZA747723B (en) * | 1974-12-11 | 1976-11-24 | Pfizer | 11-desoxy-15-substituted-omega-pentanor prostaglandins |
US4149006A (en) * | 1977-01-24 | 1979-04-10 | G. D. Searle & Co. | Prostaglandin derivatives having alkynyl, hydroxy and aryloxy junctions in the 2β side chain |
GB8329559D0 (en) * | 1983-11-04 | 1983-12-07 | Erba Farmitalia | Furyl derivatives of 16-substituted prostaglandins preparations |
SE9002596D0 (en) * | 1990-08-08 | 1990-08-08 | Pharmacia Ab | A METHOD OF SYNTHESIS OF PROSTAGLANDIN DERIVATIVES |
US5972991A (en) * | 1992-09-21 | 1999-10-26 | Allergan | Cyclopentane heptan(ene) oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents |
US6602900B2 (en) | 1992-09-21 | 2003-08-05 | Allergan, Inc. | Cyclopentane heptan(ENE)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents |
KR100578616B1 (en) * | 2004-07-23 | 2006-05-10 | 한미약품 주식회사 | Method for the preparation of d-erythro-2,2-difluoro-2-deoxy-1-oxoribose |
UA121108C2 (en) * | 2013-12-13 | 2020-04-10 | Аллерган, Інк. | Solid forms of an alpha, omega di-substituted dihydroxy cyclopentyl compound and methods for the preparation and use thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1324737A (en) * | 1970-11-02 | 1973-07-25 | Upjohn Co | Prostaglandins and the preparation thereof |
GB1386146A (en) * | 1972-05-03 | 1975-03-05 | Ici Ltd | Cyclopentane derivatives |
IL42373A (en) * | 1972-06-02 | 1977-08-31 | Pfizer | Oxaprostagliandins and their preparation |
-
1973
- 1973-07-03 ES ES416865A patent/ES416865A1/en not_active Expired
- 1973-07-03 NO NO2724/73A patent/NO143741C/en unknown
- 1973-07-05 FI FI2162/73A patent/FI57583C/en active
- 1973-07-06 IN IN1575/CAL/73A patent/IN138789B/en unknown
- 1973-07-09 IL IL42691A patent/IL42691A/en unknown
- 1973-07-09 PH PH14802A patent/PH11461A/en unknown
- 1973-07-10 DE DE19732334945 patent/DE2334945A1/en not_active Withdrawn
- 1973-07-11 CS CS734994A patent/CS201027B2/en unknown
- 1973-07-12 SU SU731948945A patent/SU644384A3/en active
- 1973-07-12 BE BE1005234A patent/BE802231A/en unknown
- 1973-07-12 CH CH1020673A patent/CH593254A5/xx not_active IP Right Cessation
- 1973-07-12 CA CA176,270A patent/CA1041495A/en not_active Expired
- 1973-07-12 DD DD172243A patent/DD109210A5/xx unknown
- 1973-07-12 HU HU73PI00000482A patent/HU172058B/en unknown
- 1973-07-12 HU HU73PI00000387A patent/HU171156B/en unknown
- 1973-07-12 HU HU73PI00000481A patent/HU171946B/en unknown
- 1973-07-12 DD DD180811*A patent/DD116459A5/xx unknown
- 1973-07-12 HU HU73PI00000480A patent/HU171158B/en unknown
- 1973-07-13 IE IE1186/73A patent/IE37909B1/en unknown
- 1973-07-13 AR AR249095A patent/AR209064A1/en active
- 1973-07-13 AT AT0620773A patent/AT367033B/en not_active IP Right Cessation
- 1973-07-13 JP JP48079214A patent/JPS5241257B2/ja not_active Expired
- 1973-07-13 FR FR7325835A patent/FR2192834B1/fr not_active Expired
- 1973-07-13 LU LU68015A patent/LU68015A1/xx unknown
- 1973-07-13 NL NL7309792A patent/NL7309792A/xx not_active Application Discontinuation
- 1973-07-13 ZA ZA734769A patent/ZA734769B/en unknown
- 1973-07-13 GB GB3121773A patent/GB1446341A/en not_active Expired
- 1973-11-07 YU YU01877/73A patent/YU187773A/en unknown
-
1974
- 1974-05-06 AR AR253775A patent/AR214383A1/en active
- 1974-09-26 NO NO743492A patent/NO144830C/en unknown
-
1975
- 1975-04-26 ES ES437037A patent/ES437037A1/en not_active Expired
- 1975-04-26 ES ES437038A patent/ES437038A1/en not_active Expired
- 1975-04-26 ES ES437039A patent/ES437039A1/en not_active Expired
- 1975-09-05 SU SU752169008A patent/SU645563A3/en active
- 1975-09-09 SU SU7502170659A patent/SU584791A3/en active
- 1975-09-11 SU SU752171155A patent/SU645564A3/en active
-
1976
- 1976-08-19 IL IL50308A patent/IL50308A0/en unknown
- 1976-11-22 JP JP14060676A patent/JPS52122349A/en active Pending
- 1976-11-22 JP JP14060576A patent/JPS5297958A/en active Pending
- 1976-11-22 JP JP14060776A patent/JPS5293753A/en active Pending
-
1977
- 1977-05-20 SE SE7705946A patent/SE7705946L/en unknown
- 1977-05-20 SE SE7705947A patent/SE7705947L/en not_active Application Discontinuation
- 1977-05-20 SE SE7705945A patent/SE7705945L/en not_active Application Discontinuation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB1456512A (en) | Substituted 16,17,18,19,20-pentanorprostaglandins | |
SE7612262L (en) | KETOPHOSPHONATE INTERMEDIATE PRODUCTS AND PROCEDURES | |
GB1383083A (en) | Thiazolidine derivatives | |
SE7705947L (en) | PROSTAGLAND PRECURSORS | |
JPS57112365A (en) | Manufacture of 5-acetamide-2,4-dimethyl- trifluoromethane sulfonanilide | |
ES444046A1 (en) | Prostanoic acid derivatives | |
ES455104A1 (en) | D-Homosteroids | |
ES418924A1 (en) | 9,11,15-Trihydroxy prost-5-enoic acid analogues | |
IT1007422B (en) | PRODUCTION OF L VALINA BY FERMENTATION | |
IT1011854B (en) | PROCEDURE FOR THE PRODUCTION OF MALTOSE BY ENZYMATIC VIA | |
ES437869A1 (en) | 2-Substituted-5,6-dimethoxyindazoles | |
IT966300B (en) | PROCEDURE FOR THE PRODUCTION OF DIANTHRACHINONYLS | |
ES399014A1 (en) | (r)-1-(2-furoyloxy)-3-methylbutyl-pencillin compounds | |
ES406644A1 (en) | Antibacterial agents | |
GB1314293A (en) | Prostaglandins and the preparation thereof | |
ES409367A1 (en) | Procedure for the preparation of methyl sulfate - 1 - (beta - hydroxyethyl) -1-guanidine. (Machine-translation by Google Translate, not legally binding) | |
GB1411065A (en) | Prostaglandin compounds | |
ES442427A1 (en) | Pyrazolidinones and a process for their preparation | |
FR2139745A2 (en) | Hypoglycaemic benzenesulphonyl ureas - n-piperidino-n'-4- - (beta-(5-methylpyrazino-2-carboxamido)ethyl)-benzenesulphonylureas | |
CA968792A (en) | Stereospecific reduction of 9,15-diketo prostaglandins | |
GB1415212A (en) | Trioxatricycloundecane derivatives and process for their manufacture | |
CA887628A (en) | Derivatives of prostanoic acid | |
SU363461A1 (en) | ALL-UNIONPATENT ~ TEKKSH; '! [: Kd5-1B.P; ^ O, c.; VABe Leader Suburban Interdistrict Production Administration of Agriculture of the Leningrad Oblast Administration of Agriculture | |
CA874983A (en) | SYNTHESIS OF N,N-DISUBSTITUTED .alpha.-AMINOACETYLENE THIOETHERS | |
ES405105A1 (en) | A process for the preparation of 2,6,6-trimethyl-1- (1 0'-carboxy-3 ', 7'-dimethyl-deca-1', 3 ', 5', 7 ', 9' - pentaenil) -cicolhexi-eno or a salt of the same. (Machine-translation by Google Translate, not legally binding) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
NAV | Patent application has lapsed |
Ref document number: 7705947-5 Format of ref document f/p: F |