SE466290B - Homogent humant fibroblastinterferon, dess framstaellning och farmaceutiska preparat paa basis daerav - Google Patents

Homogent humant fibroblastinterferon, dess framstaellning och farmaceutiska preparat paa basis daerav

Info

Publication number
SE466290B
SE466290B SE8005498A SE8005498A SE466290B SE 466290 B SE466290 B SE 466290B SE 8005498 A SE8005498 A SE 8005498A SE 8005498 A SE8005498 A SE 8005498A SE 466290 B SE466290 B SE 466290B
Authority
SE
Sweden
Prior art keywords
interferon
column
group
hplc
containing sio
Prior art date
Application number
SE8005498A
Other languages
English (en)
Swedish (sv)
Other versions
SE8005498L (sv
Inventor
H-J Friesen
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SE8005498L publication Critical patent/SE8005498L/
Publication of SE466290B publication Critical patent/SE466290B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/565IFN-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
SE8005498A 1979-07-31 1980-07-31 Homogent humant fibroblastinterferon, dess framstaellning och farmaceutiska preparat paa basis daerav SE466290B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6237179A 1979-07-31 1979-07-31
US13063580A 1980-03-14 1980-03-14

Publications (2)

Publication Number Publication Date
SE8005498L SE8005498L (sv) 1981-02-01
SE466290B true SE466290B (sv) 1992-01-27

Family

ID=26742182

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8005498A SE466290B (sv) 1979-07-31 1980-07-31 Homogent humant fibroblastinterferon, dess framstaellning och farmaceutiska preparat paa basis daerav

Country Status (33)

Country Link
US (1) US5015730A (es)
JP (1) JPH02138226A (es)
AR (1) AR229931A1 (es)
AT (1) AT372387B (es)
AU (1) AU536274B2 (es)
CA (1) CA1146468A (es)
CH (1) CH648331A5 (es)
DE (1) DE3028919A1 (es)
DK (1) DK159825C (es)
DO (1) DOP1980002948A (es)
ES (1) ES8200560A1 (es)
FI (1) FI70721C (es)
FR (1) FR2462167B1 (es)
GB (1) GB2055384B (es)
HK (1) HK40384A (es)
HU (1) HU185382B (es)
IE (1) IE50075B1 (es)
IL (1) IL60697A (es)
IT (1) IT1132269B (es)
KE (1) KE3364A (es)
LU (1) LU82673A1 (es)
MC (1) MC1337A1 (es)
MY (1) MY8500274A (es)
NL (1) NL8004361A (es)
NO (1) NO151158C (es)
NZ (1) NZ194495A (es)
PH (2) PH17738A (es)
PT (1) PT71625B (es)
RO (1) RO81474B (es)
SE (1) SE466290B (es)
YU (1) YU193480A (es)
ZA (1) ZA803943B (es)
ZW (1) ZW17980A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN156128B (es) 1980-04-03 1985-05-18 Biogen Nv
NZ198445A (en) * 1980-09-25 1984-05-31 Genentech Inc Production of human fibroblast interferon by recombinant dna technology
ZA83768B (en) * 1982-03-01 1983-10-26 Hoffmann La Roche Homogeneous human immune interferon and process therefor
US4966843A (en) * 1982-11-01 1990-10-30 Cetus Corporation Expression of interferon genes in Chinese hamster ovary cells
US4569790A (en) * 1984-03-28 1986-02-11 Cetus Corporation Process for recovering microbially produced interleukin-2 and purified recombinant interleukin-2 compositions
US4530787A (en) * 1984-03-28 1985-07-23 Cetus Corporation Controlled oxidation of microbially produced cysteine-containing proteins
US4894330A (en) * 1986-12-23 1990-01-16 Cetus Corporation Purification of recombinant beta-interferon incorporating RP-HPLC
US6346510B1 (en) 1995-10-23 2002-02-12 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions
US5723125A (en) * 1995-12-28 1998-03-03 Tanox Biosystems, Inc. Hybrid with interferon-alpha and an immunoglobulin Fc linked through a non-immunogenic peptide
US20030026779A1 (en) * 1999-10-15 2003-02-06 Liming Yu Treatment of tumors and viral infections with a hybrid conjugate of interferon and an immunoglobulin Fc
US20050002902A1 (en) * 1995-12-28 2005-01-06 Liming Yu Hybrid with interferon-alpha and an immunoglobulin Fc for treatment of tumors and viral infections
PL1917276T3 (pl) 2005-08-26 2018-08-31 Ares Trading S.A. Sposób wytwarzania glikozylowanego interferonu beta
EP1960419B1 (en) 2005-12-09 2016-03-16 Ares Trading S.A. Method for purifying fsh or a fsh mutant
WO2009053358A1 (en) * 2007-10-22 2009-04-30 Merck Serono S.A. Method for purifying fc-fusion proteins
DE102009032179A1 (de) 2009-07-07 2011-01-13 Biogenerix Ag Verfahren zur Reinigung von Interferon beta

Also Published As

Publication number Publication date
PH17738A (en) 1984-11-23
GB2055384A (en) 1981-03-04
IT8023801A0 (it) 1980-07-30
NL8004361A (nl) 1981-02-03
PT71625B (en) 1981-12-17
JPH02138226A (ja) 1990-05-28
IE801589L (en) 1981-01-31
NO151158C (no) 1985-02-20
IT1132269B (it) 1986-07-02
DE3028919A1 (de) 1981-02-19
GB2055384B (en) 1983-08-10
CA1146468A (en) 1983-05-17
ZW17980A1 (en) 1981-03-18
KE3364A (en) 1984-02-03
FI70721C (fi) 1986-10-06
ES493849A0 (es) 1981-11-16
PT71625A (en) 1980-08-01
FR2462167B1 (fr) 1985-07-05
DK159825B (da) 1990-12-10
HU185382B (en) 1985-01-28
DE3028919C2 (es) 1988-02-18
NZ194495A (en) 1984-07-31
MC1337A1 (fr) 1981-04-21
RO81474A (ro) 1983-04-29
ZA803943B (en) 1981-06-24
ATA395080A (de) 1983-02-15
FI802400A (fi) 1981-02-01
IL60697A (en) 1984-04-30
PH18479A (en) 1985-07-18
RO81474B (ro) 1983-04-30
DK328880A (da) 1981-02-01
FI70721B (fi) 1986-06-26
AU6091480A (en) 1981-02-05
NO802297L (no) 1981-02-02
AR229931A1 (es) 1984-01-31
YU193480A (en) 1984-04-30
MY8500274A (en) 1985-12-31
ES8200560A1 (es) 1981-11-16
SE8005498L (sv) 1981-02-01
IE50075B1 (en) 1986-02-05
DK159825C (da) 1991-04-29
AT372387B (de) 1983-09-26
IL60697A0 (en) 1980-09-16
HK40384A (en) 1984-05-18
CH648331A5 (de) 1985-03-15
AU536274B2 (en) 1984-05-03
US5015730A (en) 1991-05-14
DOP1980002948A (es) 1989-04-20
NO151158B (no) 1984-11-12
LU82673A1 (fr) 1982-02-17
FR2462167A1 (fr) 1981-02-13

Similar Documents

Publication Publication Date Title
US4289689A (en) Preparation of homogeneous human fibroblast interferon
SE466290B (sv) Homogent humant fibroblastinterferon, dess framstaellning och farmaceutiska preparat paa basis daerav
Rubinstein et al. Human leukocyte interferon: production, purification to homogeneity, and initial characterization.
Staehelin et al. Purification and characterization of recombinant human leukocyte interferon (IFLrA) with monoclonal antibodies.
KR830002616B1 (ko) 단백질의 정제방법
US4617378A (en) Purification of biologically active human immune interferon
US4908432A (en) Novel polypeptide having gamma-interferon activity
JPH031320B2 (es)
US5338834A (en) Ultrapure human interleukin-6
KR940010024B1 (ko) α-인터페론의 제조 및 정제 방법
Lobb et al. Comparison of human and bovine brain derived heparin-binding growth factors
KR840001516B1 (ko) 인체 섬유아세포 인터페론의 제조방법
Rubinstein et al. [67] Purification and characterization of human leukocyte interferons by high-performance liquid chromatography
Friesen et al. [63] Purification of human fibroblast interferon by high-performance liquid chromatography
Yokotsuka et al. Fractionation of whole histone by partition chromatography on Sephadex G-25
Rubinstein Purification and structural analysis of interferon
MXPA06006357A (es) Proceso para purificar interferon beta.
Yamauchi et al. Isolation and analysis of glycopeptides from polymorphic variants of α1-acid glycoprotein of human plasma
IE882146L (en) Purification of gm-csf
Braude [27] Purification of natural human immune interferon induced by A-23187 and Mezerein
Herring et al. Rapid purification of leukocyte interferons by high-performance liquid chromatography
Körner et al. Simple preparative two-step purification of interleukin-2 from culture medium of lectin stimulated normal human lymphocytes

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8005498-4

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8005498-4

Format of ref document f/p: F