SE452325B - 10-alkynyl-steroider samt forfarande for framstellning av dessa - Google Patents
10-alkynyl-steroider samt forfarande for framstellning av dessaInfo
- Publication number
- SE452325B SE452325B SE8103963A SE8103963A SE452325B SE 452325 B SE452325 B SE 452325B SE 8103963 A SE8103963 A SE 8103963A SE 8103963 A SE8103963 A SE 8103963A SE 452325 B SE452325 B SE 452325B
- Authority
- SE
- Sweden
- Prior art keywords
- propynyl
- compound
- dione
- give
- estr
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/008—Ketals at position 17
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16345180A | 1980-06-27 | 1980-06-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8103963L SE8103963L (sv) | 1981-12-28 |
SE452325B true SE452325B (sv) | 1987-11-23 |
Family
ID=22590066
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8103963A SE452325B (sv) | 1980-06-27 | 1981-06-24 | 10-alkynyl-steroider samt forfarande for framstellning av dessa |
Country Status (23)
Country | Link |
---|---|
US (1) | US4322416A (no) |
JP (1) | JPS5738797A (no) |
AT (1) | AT385510B (no) |
AU (1) | AU542273B2 (no) |
BE (1) | BE889401A (no) |
CA (1) | CA1173431A (no) |
CH (1) | CH646984A5 (no) |
DE (1) | DE3124780A1 (no) |
DK (2) | DK161151C (no) |
ES (1) | ES8302025A1 (no) |
FR (1) | FR2485543A1 (no) |
GB (2) | GB2078749B (no) |
HK (1) | HK72686A (no) |
IE (1) | IE51351B1 (no) |
IL (1) | IL63143A (no) |
IT (1) | IT1171339B (no) |
MY (1) | MY8700055A (no) |
NL (1) | NL8103101A (no) |
NO (1) | NO156693C (no) |
NZ (1) | NZ197494A (no) |
PH (1) | PH16787A (no) |
SE (1) | SE452325B (no) |
ZA (1) | ZA814220B (no) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0100566B1 (en) * | 1982-07-14 | 1986-02-19 | Akzo N.V. | Novel 19-thio-androstane derivatives |
ATE37871T1 (de) * | 1982-12-21 | 1988-10-15 | Ciba Geigy Ag | Substituierte azabicycloalkane, ihre verwendung, pharmazeutische praeparate, welche diese verbindungen enthalten, und verfahren zur herstellung dieser verbindungen. |
DE3323321A1 (de) * | 1983-06-24 | 1985-01-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Prophylaxe und therapie von koronaren herzkrankheiten durch senkung des oestrogenspiegels |
DE3338212C2 (de) * | 1983-10-18 | 1995-05-18 | Schering Ag | 1-Methyl-androsta-1,4,6-trien-3,17-dione, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate |
US4634694A (en) * | 1984-01-14 | 1987-01-06 | Akzo N.V. | Novel Δ4 - and Δ5 -androstene derivatives and pharmaceutical compositions containing these derivatives |
US4546098A (en) * | 1984-04-13 | 1985-10-08 | The Rockefeller University | Estrogen synthesis inhibitors |
FR2569408B1 (fr) * | 1984-08-24 | 1986-10-03 | Roussel Uclaf | Nouveaux steroides substitues en position 10 par un radical comportant une double ou triple liaison, leur procede de preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant |
GB8531747D0 (en) * | 1985-12-24 | 1986-02-05 | Erba Farmitalia | 10beta-alkynylestrene derivatives |
FR2594829B1 (fr) * | 1986-02-24 | 1988-06-03 | Roussel Uclaf | Nouveaux steroides 9 (11) satures substitues en position 10 par un radical comportant une triple liaison, leur procede de preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant |
FR2594830B1 (fr) * | 1986-02-24 | 1988-06-03 | Roussel Uclaf | Nouveaux 13 epi ou d-homo steroides substitues en position 10b par un radical comportant une double ou triple liaison, leur procede de preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant |
US4874891A (en) * | 1986-05-01 | 1989-10-17 | Washington University | Open "D" ring hormone analogs |
US4910191A (en) * | 1988-06-28 | 1990-03-20 | Merrell Dow Pharmaceuticals Inc. | 19-substituted progesterone derivatives useful as 19-hydroxylase inhibitors |
US4882322A (en) * | 1988-10-27 | 1989-11-21 | Merrell Dow Pharmaceuticals Inc. | 3β,17β-hydroxy-substituted steroids and related steroidal compounds |
FR2640976B1 (no) * | 1988-12-22 | 1994-10-28 | Roussel Uclaf | |
US5162337A (en) * | 1990-10-05 | 1992-11-10 | Merck & Co., Inc. | Animal growth promotion |
US5166201A (en) * | 1990-11-30 | 1992-11-24 | Merrell Dow Pharmaceuticals Inc. | 2β,19-ethylene bridged steroids as aromatase inhibitors |
US5126488A (en) * | 1990-11-30 | 1992-06-30 | Merrell Dow Pharmaceuticals Inc. | 2β,19-methyleneamino bridged steroids as aromatase inhibitors |
CH683151A5 (de) * | 1991-04-24 | 1994-01-31 | Ciba Geigy Ag | Antikonzeption bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus. |
FR2677027B1 (fr) * | 1991-05-27 | 1993-09-10 | Roussel Uclaf | Nouveaux produits sterouides substitues en position 6, et comportant, en position 10, un radical thioethyle, leur procede de preparation leurs intermediaires, leur application comme medicaments. |
DE4435368A1 (de) * | 1994-09-22 | 1996-03-28 | Schering Ag | Verwendung von Aromatasehemmern zur Herstellung eines Arzneimittels zur Behandlung eines relativen Androgenmangels beim Mann |
US5866558A (en) * | 1997-05-08 | 1999-02-02 | Regents Of The University Of Minnesota | 6-alkynyl steroids |
EP1854465A1 (en) * | 2006-05-12 | 2007-11-14 | Alexander Tobias Teichmann | Use of 4,17 beta-dihydroxyandrost-4-ene-3-one for treating cancers |
CN102884072A (zh) | 2010-04-08 | 2013-01-16 | 爱默蕾大学 | 被取代的雄甾-4-烯二酮 |
EP3666276A1 (en) | 2018-12-14 | 2020-06-17 | dcic Biopharmaceutical Limited | Medication against estrogen-receptor beta (erbeta) positive breast tumor |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3127427A (en) * | 1962-07-17 | 1964-03-31 | Hoffmann La Roche | 10-alkenyl-steroids and process therefor |
US3218316A (en) * | 1963-08-26 | 1965-11-16 | Syntex Corp | 10beta-ethynyl-19-norandrostane derivatives |
-
1981
- 1981-04-27 US US06/258,214 patent/US4322416A/en not_active Expired - Lifetime
- 1981-06-20 IL IL63143A patent/IL63143A/xx not_active IP Right Cessation
- 1981-06-22 PH PH25798A patent/PH16787A/en unknown
- 1981-06-22 ZA ZA814220A patent/ZA814220B/xx unknown
- 1981-06-22 NZ NZ197494A patent/NZ197494A/en unknown
- 1981-06-22 CH CH411981A patent/CH646984A5/de not_active IP Right Cessation
- 1981-06-22 DK DK274681A patent/DK161151C/da not_active IP Right Cessation
- 1981-06-22 CA CA000380295A patent/CA1173431A/en not_active Expired
- 1981-06-24 DE DE19813124780 patent/DE3124780A1/de active Granted
- 1981-06-24 SE SE8103963A patent/SE452325B/sv not_active IP Right Cessation
- 1981-06-25 ES ES503345A patent/ES8302025A1/es not_active Expired
- 1981-06-26 BE BE0/205229A patent/BE889401A/fr not_active IP Right Cessation
- 1981-06-26 NO NO812197A patent/NO156693C/no not_active IP Right Cessation
- 1981-06-26 JP JP9849481A patent/JPS5738797A/ja active Granted
- 1981-06-26 AT AT0285781A patent/AT385510B/de not_active IP Right Cessation
- 1981-06-26 NL NL8103101A patent/NL8103101A/nl not_active IP Right Cessation
- 1981-06-26 IE IE1434/81A patent/IE51351B1/en not_active IP Right Cessation
- 1981-06-26 GB GB8119813A patent/GB2078749B/en not_active Expired
- 1981-06-26 IT IT8148780A patent/IT1171339B/it active
- 1981-06-26 FR FR8112642A patent/FR2485543A1/fr active Granted
- 1981-06-30 AU AU72370/81A patent/AU542273B2/en not_active Ceased
-
1983
- 1983-06-20 GB GB08316702A patent/GB2135314B/en not_active Expired
-
1986
- 1986-09-25 HK HK726/86A patent/HK72686A/xx not_active IP Right Cessation
-
1987
- 1987-12-30 MY MY55/87A patent/MY8700055A/xx unknown
-
1990
- 1990-03-22 DK DK075190A patent/DK162447C/da not_active IP Right Cessation
Also Published As
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