ES503345A0 - Procedimiento para la preparacion de 10-alquinil esteroides - Google Patents

Procedimiento para la preparacion de 10-alquinil esteroides

Info

Publication number: ES503345A0
Authority: ES; Spain
Prior art keywords: procedure; preparation; steroids; alkynyl; alkynyl steroids
Prior art date: 1980-06-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES503345A

Other languages

English (en)

Other versions

ES8302025A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Aventis Pharmaceuticals Inc

Original Assignee

Merrell Dow Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-06-27

Filing date

1981-06-25

Publication date

1983-01-01

1981-06-25 Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc

1983-01-01 Publication of ES503345A0 publication Critical patent/ES503345A0/es

1983-01-01 Publication of ES8302025A1 publication Critical patent/ES8302025A1/es

Status Expired legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/008—Ketals at position 17

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES503345A 1980-06-27 1981-06-25 Procedimiento para la preparacion de 10-alquinil esteroides Expired ES8302025A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US16345180A	1980-06-27	1980-06-27

Publications (2)

Publication Number	Publication Date
ES503345A0 true ES503345A0 (es)	1983-01-01
ES8302025A1 ES8302025A1 (es)	1983-01-01

Family

ID=22590066

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES503345A Expired ES8302025A1 (es)	1980-06-27	1981-06-25	Procedimiento para la preparacion de 10-alquinil esteroides

Country Status (23)

Country	Link
US (1)	US4322416A (es)
JP (1)	JPS5738797A (es)
AT (1)	AT385510B (es)
AU (1)	AU542273B2 (es)
BE (1)	BE889401A (es)
CA (1)	CA1173431A (es)
CH (1)	CH646984A5 (es)
DE (1)	DE3124780A1 (es)
DK (2)	DK161151C (es)
ES (1)	ES8302025A1 (es)
FR (1)	FR2485543A1 (es)
GB (2)	GB2078749B (es)
HK (1)	HK72686A (es)
IE (1)	IE51351B1 (es)
IL (1)	IL63143A (es)
IT (1)	IT1171339B (es)
MY (1)	MY8700055A (es)
NL (1)	NL8103101A (es)
NO (1)	NO156693C (es)
NZ (1)	NZ197494A (es)
PH (1)	PH16787A (es)
SE (1)	SE452325B (es)
ZA (1)	ZA814220B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3362176D1 (en) *	1982-07-14	1986-03-27	Akzo Nv	Novel 19-thio-androstane derivatives
DE3378208D1 (en) *	1982-12-21	1988-11-17	Ciba Geigy Ag	Substituted azabicycloalkanes, their use, pharmaceutical preparations containing these compounds and process for preparing these compounds
DE3323321A1 (de) *	1983-06-24	1985-01-03	Schering AG, 1000 Berlin und 4709 Bergkamen	Prophylaxe und therapie von koronaren herzkrankheiten durch senkung des oestrogenspiegels
DE3338212C2 (de) *	1983-10-18	1995-05-18	Schering Ag	1-Methyl-androsta-1,4,6-trien-3,17-dione, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate
US4634694A (en) *	1984-01-14	1987-01-06	Akzo N.V.	Novel Δ4 - and Δ5 -androstene derivatives and pharmaceutical compositions containing these derivatives
US4546098A (en) *	1984-04-13	1985-10-08	The Rockefeller University	Estrogen synthesis inhibitors
FR2569408B1 (fr) *	1984-08-24	1986-10-03	Roussel Uclaf	Nouveaux steroides substitues en position 10 par un radical comportant une double ou triple liaison, leur procede de preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant
GB8531747D0 (en) *	1985-12-24	1986-02-05	Erba Farmitalia	10beta-alkynylestrene derivatives
FR2594829B1 (fr) *	1986-02-24	1988-06-03	Roussel Uclaf	Nouveaux steroides 9 (11) satures substitues en position 10 par un radical comportant une triple liaison, leur procede de preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant
FR2594830B1 (fr) *	1986-02-24	1988-06-03	Roussel Uclaf	Nouveaux 13 epi ou d-homo steroides substitues en position 10b par un radical comportant une double ou triple liaison, leur procede de preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant
US4874891A (en) *	1986-05-01	1989-10-17	Washington University	Open "D" ring hormone analogs
US4910191A (en) *	1988-06-28	1990-03-20	Merrell Dow Pharmaceuticals Inc.	19-substituted progesterone derivatives useful as 19-hydroxylase inhibitors
US4882322A (en) *	1988-10-27	1989-11-21	Merrell Dow Pharmaceuticals Inc.	3β,17β-hydroxy-substituted steroids and related steroidal compounds
FR2640976B1 (es) *	1988-12-22	1994-10-28	Roussel Uclaf
US5162337A (en) *	1990-10-05	1992-11-10	Merck & Co., Inc.	Animal growth promotion
US5166201A (en) *	1990-11-30	1992-11-24	Merrell Dow Pharmaceuticals Inc.	2β,19-ethylene bridged steroids as aromatase inhibitors
US5126488A (en) *	1990-11-30	1992-06-30	Merrell Dow Pharmaceuticals Inc.	2β,19-methyleneamino bridged steroids as aromatase inhibitors
CH683151A5 (de) *	1991-04-24	1994-01-31	Ciba Geigy Ag	Antikonzeption bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus.
FR2677027B1 (fr) *	1991-05-27	1993-09-10	Roussel Uclaf	Nouveaux produits sterouides substitues en position 6, et comportant, en position 10, un radical thioethyle, leur procede de preparation leurs intermediaires, leur application comme medicaments.
DE4435368A1 (de) *	1994-09-22	1996-03-28	Schering Ag	Verwendung von Aromatasehemmern zur Herstellung eines Arzneimittels zur Behandlung eines relativen Androgenmangels beim Mann
US5866558A (en) *	1997-05-08	1999-02-02	Regents Of The University Of Minnesota	6-alkynyl steroids
EP1854465A1 (en) *	2006-05-12	2007-11-14	Alexander Tobias Teichmann	Use of 4,17 beta-dihydroxyandrost-4-ene-3-one for treating cancers
AU2011237592B2 (en)	2010-04-08	2016-10-27	Emory University	Substituted androst-4-ene diones
EP3666276A1 (en)	2018-12-14	2020-06-17	dcic Biopharmaceutical Limited	Medication against estrogen-receptor beta (erbeta) positive breast tumor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3127427A (en) *	1962-07-17	1964-03-31	Hoffmann La Roche	10-alkenyl-steroids and process therefor
US3218316A (en) *	1963-08-26	1965-11-16	Syntex Corp	10beta-ethynyl-19-norandrostane derivatives

1981
- 1981-04-27 US US06/258,214 patent/US4322416A/en not_active Expired - Lifetime
- 1981-06-20 IL IL63143A patent/IL63143A/xx not_active IP Right Cessation
- 1981-06-22 CH CH411981A patent/CH646984A5/de not_active IP Right Cessation
- 1981-06-22 NZ NZ197494A patent/NZ197494A/en unknown
- 1981-06-22 ZA ZA814220A patent/ZA814220B/xx unknown
- 1981-06-22 PH PH25798A patent/PH16787A/en unknown
- 1981-06-22 DK DK274681A patent/DK161151C/da not_active IP Right Cessation
- 1981-06-22 CA CA000380295A patent/CA1173431A/en not_active Expired
- 1981-06-24 SE SE8103963A patent/SE452325B/sv not_active IP Right Cessation
- 1981-06-24 DE DE19813124780 patent/DE3124780A1/de active Granted
- 1981-06-25 ES ES503345A patent/ES8302025A1/es not_active Expired
- 1981-06-26 NO NO812197A patent/NO156693C/no not_active IP Right Cessation
- 1981-06-26 NL NL8103101A patent/NL8103101A/nl not_active IP Right Cessation
- 1981-06-26 AT AT0285781A patent/AT385510B/de not_active IP Right Cessation
- 1981-06-26 IE IE1434/81A patent/IE51351B1/en not_active IP Right Cessation
- 1981-06-26 GB GB8119813A patent/GB2078749B/en not_active Expired
- 1981-06-26 FR FR8112642A patent/FR2485543A1/fr active Granted
- 1981-06-26 BE BE0/205229A patent/BE889401A/fr not_active IP Right Cessation
- 1981-06-26 JP JP9849481A patent/JPS5738797A/ja active Granted
- 1981-06-26 IT IT8148780A patent/IT1171339B/it active
- 1981-06-30 AU AU72370/81A patent/AU542273B2/en not_active Ceased
1983
- 1983-06-20 GB GB08316702A patent/GB2135314B/en not_active Expired
1986
- 1986-09-25 HK HK726/86A patent/HK72686A/xx not_active IP Right Cessation
1987
- 1987-12-30 MY MY55/87A patent/MY8700055A/xx unknown
1990
- 1990-03-22 DK DK075190A patent/DK162447C/da not_active IP Right Cessation

Also Published As

Publication number	Publication date
ATA285781A (de)	1987-09-15
IE51351B1 (en)	1986-12-10
IT1171339B (it)	1987-06-10
DE3124780A1 (de)	1982-06-03
SE8103963L (sv)	1981-12-28
JPS5738797A (en)	1982-03-03
NL192455C (es)	1997-08-04
GB2135314A (en)	1984-08-30
GB2078749B (en)	1983-11-16
NO156693B (no)	1987-07-27
GB2135314B (en)	1985-04-17
DK162447C (da)	1992-03-23
NO156693C (no)	1987-11-04
DE3124780C2 (es)	1992-04-23
DK161151C (da)	1991-11-18
BE889401A (fr)	1981-12-28
AT385510B (de)	1988-04-11
AU542273B2 (en)	1985-02-14
DK75190D0 (da)	1990-03-22
MY8700055A (en)	1987-12-31
FR2485543B1 (es)	1983-12-23
GB2078749A (en)	1982-01-13
PH16787A (en)	1984-02-22
NZ197494A (en)	1984-11-09
DK274681A (da)	1981-12-28
IL63143A (en)	1984-10-31
ES8302025A1 (es)	1983-01-01
IE811434L (en)	1981-12-27
CA1173431A (en)	1984-08-28
NL192455B (es)	1997-04-01
IL63143A0 (en)	1981-09-13
CH646984A5 (de)	1984-12-28
DK162447B (da)	1991-10-28
AU7237081A (en)	1982-01-07
NL8103101A (nl)	1982-01-18
US4322416A (en)	1982-03-30
IT8148780A0 (it)	1981-06-26
HK72686A (en)	1986-10-03
NO812197L (no)	1981-12-28
GB8316702D0 (en)	1983-07-20
FR2485543A1 (fr)	1981-12-31
SE452325B (sv)	1987-11-23
ZA814220B (en)	1982-07-28
DK161151B (da)	1991-06-03
DK75190A (da)	1990-03-22
JPH021159B2 (es)	1990-01-10

Publication	Publication Date	Title
ES503345A0 (es)	1983-01-01	Procedimiento para la preparacion de 10-alquinil esteroides
MX6869E (es)	1986-09-11	Procedimiento para la preparacion de dibenzimidiazoazepinas
ES502546A0 (es)	1982-04-01	Procedimiento para la preparacion de nuevas n-ariloxazolidi-nonas-2
AR228468A1 (es)	1983-03-15	Procedimiento para la preparacion de nuevas imidazolil-fenilamidinas
AR226202A1 (es)	1982-06-15	Procedimiento para la preparacion de 7-acil-3-yodometil-cefalosporinas
MX160977A (es)	1990-06-29	Procedimiento para la preparacion de cloroformiatos alfa-clorados
MX7419E (es)	1988-10-18	Procedimiento para la preparacion de pss-asa
MX157607A (es)	1988-12-05	Procedimiento para la preparacion de ciclohexilamina
AR231288A1 (es)	1984-10-31	Procedimiento para la preparacion de 3-amido-n-/2-5-dimetilaminometil-furan-2-il-metiltio etil-benzamidas
MX155760A (es)	1988-04-25	Procedimiento para la preparacion de 1-amino-4-hidroxi-2-fenoxiantraquinonas o 1-amino-4-hidroxi-2-alcoxiantraquinonas
ES501464A0 (es)	1982-02-16	Procedimiento para la preparacion de nuevas fenilureas
ES524614A0 (es)	1984-05-01	Procedimiento de preparacion de nuevos amino-14 esteroides.
ES503975A0 (es)	1982-04-16	Procedimiento para la preparacion de nuevas fenilureas
ES500068A0 (es)	1981-12-16	Procedimiento para la obtencion de nuevos tioles
AR229890A1 (es)	1983-12-30	Procedimiento para la preparacion de 1-carvona
ES500071A0 (es)	1982-01-01	Procedimiento para la preparacion de nuevos 2-nitro-5-feno- xifenil-oxazoles,-oxacinas,-imidazoles,-pirimidinas o-tiazo-les
MX6707E (es)	1985-10-23	Procedimiento para la preparacion de n(1-alil-2-pirrolidinilmetil)-2-metoxi-4-amino-5-metil-sulfamoil-benzamida
AR229350A1 (es)	1983-07-29	Procedimiento para la preparacion de nuevas guanilamidinas
ES505095A0 (es)	1982-08-16	Procedimiento para la preparacion de nuevas pirazinas
ES527552A0 (es)	1985-04-16	Procedimiento para la preparacion de acridanona
ES499209A0 (es)	1982-06-01	Procedimiento para la preparacion de 3-desoxi-a15-esteroides
ES505324A0 (es)	1982-08-16	Procedimiento para la preparacion de 4-carbamoiloxi-oxaza- fosforinas
AR223383A1 (es)	1981-08-14	Procedimiento para la preparacion de 2-isopropilamino-pirimidina
ES524727A0 (es)	1985-01-01	Procedimiento para la preparacion de n-acetil-4-triazolidincarboxilato de guayacol
AR230439A1 (es)	1984-04-30	Proceso para la preparacion de 2-isopropilaminopirimidina-n-oxido