SE435278B - 5-cyano-1-legre(c?711?71-?714)alkyl-pyrrol-2-ettiksyra, framstellning derav och anvendningen som mellanprodukt vid framstellning av terapeutiskt verksamma pyrrolderivat - Google Patents

5-cyano-1-legre(c?711?71-?714)alkyl-pyrrol-2-ettiksyra, framstellning derav och anvendningen som mellanprodukt vid framstellning av terapeutiskt verksamma pyrrolderivat

Info

Publication number
SE435278B
SE435278B SE7811704A SE7811704A SE435278B SE 435278 B SE435278 B SE 435278B SE 7811704 A SE7811704 A SE 7811704A SE 7811704 A SE7811704 A SE 7811704A SE 435278 B SE435278 B SE 435278B
Authority
SE
Sweden
Prior art keywords
cyano
preparation
acetic acid
reaction
pyrrole
Prior art date
Application number
SE7811704A
Other languages
English (en)
Swedish (sv)
Other versions
SE7811704L (sv
Inventor
K Kondo
M Suda
D Tunemoto
Original Assignee
Sagami Chem Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP14658177A external-priority patent/JPS5490171A/ja
Priority claimed from JP14658277A external-priority patent/JPS5481264A/ja
Application filed by Sagami Chem Res filed Critical Sagami Chem Res
Publication of SE7811704L publication Critical patent/SE7811704L/xx
Publication of SE435278B publication Critical patent/SE435278B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SE7811704A 1977-12-08 1978-11-13 5-cyano-1-legre(c?711?71-?714)alkyl-pyrrol-2-ettiksyra, framstellning derav och anvendningen som mellanprodukt vid framstellning av terapeutiskt verksamma pyrrolderivat SE435278B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14658177A JPS5490171A (en) 1977-12-08 1977-12-08 5-cyano-1-methylpyrrole-2-acetic acid and its preparation
JP14658277A JPS5481264A (en) 1977-12-08 1977-12-08 Preparation of 1-methyl-5-aroylpryrrole-2-acetic acid

Publications (2)

Publication Number Publication Date
SE7811704L SE7811704L (sv) 1979-06-09
SE435278B true SE435278B (sv) 1984-09-17

Family

ID=26477382

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7811704A SE435278B (sv) 1977-12-08 1978-11-13 5-cyano-1-legre(c?711?71-?714)alkyl-pyrrol-2-ettiksyra, framstellning derav och anvendningen som mellanprodukt vid framstellning av terapeutiskt verksamma pyrrolderivat

Country Status (16)

Country Link
US (1) US4238396A (fr)
AU (1) AU529229B2 (fr)
CA (1) CA1121364A (fr)
CH (1) CH644103A5 (fr)
DE (1) DE2852975C2 (fr)
DK (1) DK553378A (fr)
ES (1) ES475807A1 (fr)
FI (1) FI66848C (fr)
FR (2) FR2411180A1 (fr)
GB (1) GB2014131B (fr)
IE (1) IE47793B1 (fr)
IT (1) IT1157750B (fr)
LU (1) LU80620A1 (fr)
NL (1) NL7811940A (fr)
PH (2) PH15394A (fr)
SE (1) SE435278B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4359422A (en) * 1979-04-09 1982-11-16 Ethyl Corporation Acid stabilized compositions of 2,2,2-trichloro-1-(N-hydrocarbylpyrryl-2)-ethanol
US4246175A (en) 1979-05-29 1981-01-20 Ethyl Corporation Synthesis of 5-cyano-1-hydrocarbylpyrrole-2-acetic acid
US4335136A (en) * 1980-04-18 1982-06-15 E. I. Du Pont De Nemours And Company Anti-inflammatory 4,5-diaryl-α-(polyfluoroalkyl)-1H-pyrrole-2-methanamines
EP0044485A1 (fr) * 1980-07-21 1982-01-27 E.I. Du Pont De Nemours And Company 2,3-Diaryl-5-(2,2,2-trifluoro-1-(trifluorométhyl)éthyl)-1H-pyrroles anti-inflammatoires
US4528382A (en) * 1982-11-16 1985-07-09 Mcneilab, Inc. Imidoyl substituted pyrroles

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313852A (en) * 1960-06-03 1967-04-11 Smith Kline French Lab Trifluoromethyl substituted o-aminophenyl ketimines
US3752826A (en) * 1970-01-26 1973-08-14 Mcneilab Inc Aroyl substituted pyrroles
SE396949B (sv) * 1970-06-15 1977-10-10 Mcneilab Inc Forfarande for framstellning av aroyl-substituerade pyrroler med terapeutisk verkan
BE794161A (fr) * 1972-01-21 1973-07-17 Mcneilab Inc Acides 5-cinnamoyl-pyrrole-2-acetiques et leurs esters
US3803171A (en) * 1972-01-21 1974-04-09 Mc Neil Labor Inc 5-phenylacetyl-pyrroles
US3998844A (en) * 1975-06-02 1976-12-27 Mcneil Laboratories, Incorporated Uncatalyzed aroylation of 1-alkylpyrrole-2-acetic acid derivatives

Also Published As

Publication number Publication date
US4238396A (en) 1980-12-09
GB2014131A (en) 1979-08-22
DE2852975A1 (de) 1979-06-13
CH644103A5 (de) 1984-07-13
IT7852240A0 (it) 1978-12-07
FI66848B (fi) 1984-08-31
GB2014131B (en) 1982-09-02
DE2852975C2 (de) 1982-04-08
PH15394A (en) 1982-12-23
FR2414040B1 (fr) 1982-03-05
FR2411180A1 (fr) 1979-07-06
DK553378A (da) 1979-06-09
CA1121364A (fr) 1982-04-06
FR2414040A1 (fr) 1979-08-03
FR2411180B1 (fr) 1982-07-09
NL7811940A (nl) 1979-06-12
IT1157750B (it) 1987-02-18
IE47793B1 (en) 1984-06-27
AU4231378A (en) 1979-06-14
LU80620A1 (de) 1979-06-15
ES475807A1 (es) 1979-04-16
FI783768A (fi) 1979-06-09
PH17068A (en) 1984-05-24
FI66848C (fi) 1984-12-10
SE7811704L (sv) 1979-06-09
AU529229B2 (en) 1983-06-02
IE782419L (en) 1979-06-08

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