SE421318B - Forfarande for framstellning av antracyklinglykosidor - Google Patents

Forfarande for framstellning av antracyklinglykosidor

Info

Publication number
SE421318B
SE421318B SE7606808A SE7606808A SE421318B SE 421318 B SE421318 B SE 421318B SE 7606808 A SE7606808 A SE 7606808A SE 7606808 A SE7606808 A SE 7606808A SE 421318 B SE421318 B SE 421318B
Authority
SE
Sweden
Prior art keywords
gycosides
antracycling
procedure
manufacturing
manufacturing antracycling
Prior art date
Application number
SE7606808A
Other languages
English (en)
Swedish (sv)
Other versions
SE7606808L (sv
Inventor
F Arcamone
L Bernardi
B Patelli
S Penco
Original Assignee
Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia
Publication of SE7606808L publication Critical patent/SE7606808L/xx
Publication of SE421318B publication Critical patent/SE421318B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE7606808A 1976-06-14 1976-06-15 Forfarande for framstellning av antracyklinglykosidor SE421318B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7617955A FR2355028A1 (fr) 1976-06-14 1976-06-14 Procede pour la preparation de glycosides derives d'anthracyclines optiquement actives

Publications (2)

Publication Number Publication Date
SE7606808L SE7606808L (sv) 1977-12-16
SE421318B true SE421318B (sv) 1981-12-14

Family

ID=9174331

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7606808A SE421318B (sv) 1976-06-14 1976-06-15 Forfarande for framstellning av antracyklinglykosidor
SE8100471A SE447988B (sv) 1976-06-14 1981-01-26 Forfarande for uppdelning av racemiska aglykoner

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE8100471A SE447988B (sv) 1976-06-14 1981-01-26 Forfarande for uppdelning av racemiska aglykoner

Country Status (11)

Country Link
US (1) US4107423A (fr)
JP (1) JPS532463A (fr)
AT (2) AT344899B (fr)
BE (1) BE842930A (fr)
CA (1) CA1046510A (fr)
CH (1) CH622529A5 (fr)
DE (1) DE2626783C2 (fr)
FR (1) FR2355028A1 (fr)
GB (1) GB1509875A (fr)
NL (2) NL175300C (fr)
SE (2) SE421318B (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1567456A (en) * 1976-11-16 1980-05-14 Farmaceutici Italia Daunomycin derivatives
IL55431A (en) * 1978-08-24 1982-07-30 Yeda Res & Dev Anthracycline type antibiotics,their preparation and pharmaceutical compositions comprising them
NL8001417A (nl) * 1979-03-17 1980-09-19 Erba Farmitalia Antitumorglycosiden.
GB2056443B (en) * 1979-08-20 1984-01-18 Hoffmann La Roche Cyclic compounds
JPS56135021A (en) * 1980-03-25 1981-10-22 Nippon Kokan Kk <Nkk> Lining for internal surface of welded part of steel pipe
CA1174669A (fr) * 1980-07-18 1984-09-18 Michael J. Broadhurst Glucosides d'anthracycline
GB8317037D0 (en) * 1983-06-23 1983-07-27 Erba Farmitalia 6-deoxyanthracyclines
US4540695A (en) * 1981-08-12 1985-09-10 Sumitomo Chemical Co., Ltd. Aminonaphthacene derivatives and their use
NL8300150A (nl) * 1982-01-26 1983-08-16 Erba Farmitalia Daunorubicine en doxorubicine-analoga, hun bereiding en toepassing.
AU554416B2 (en) * 1982-05-24 1986-08-21 Farmitalia Carlo Erba S.P.A. Anthracycline glycosides
JPS59212499A (ja) * 1983-05-13 1984-12-01 アドリヤ・ラボラトリ−ズ・インコ−ポレ−テツド 抗腫瘍性抗生物質アントラサイクリンの４−デメトキシ−３′−デアミノ−３′（４−モリホリニル）誘導体
US4831019A (en) * 1983-10-31 1989-05-16 Adria Laboratories, Inc. Pharmaceutical preparations of 4-demethoxy-n-trifluoroacetyl anthracyclines
US4496485A (en) * 1983-11-25 1985-01-29 G. D. Searle & Co. Asymmetric 7-O-(substituted acetyl)-4-demethoxydaunomycinones
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation
GB8803301D0 (en) * 1988-02-12 1988-03-09 Erba Carlo Spa Process for preparation of 4-demethoxy-daunomycinone aglycone of 4-demethoxy-daunorubicin
GB9418260D0 (en) * 1994-09-09 1994-10-26 Erba Carlo Spa Anthracycline derivatives
DE10155016A1 (de) * 2001-11-07 2003-05-15 Knoell Hans Forschung Ev Neue Chinon-Verbindung, Verfahren zur Herstellung und deren Verwendung
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
US8551973B2 (en) 2008-12-23 2013-10-08 Gilead Pharmasset Llc Nucleoside analogs
US8716263B2 (en) 2008-12-23 2014-05-06 Gilead Pharmasset Llc Synthesis of purine nucleosides
EP3222628A1 (fr) 2008-12-23 2017-09-27 Gilead Pharmasset LLC Phosphoramidates nucléosidiques
PT3290428T (pt) 2010-03-31 2021-12-27 Gilead Pharmasset Llc Comprimido compreendendo 2-(((s)-(((2r,3r,4r,5r)-5-(2,4-dioxo-3,4-dihidropirimidin-1-(2h)-il)¿4¿fluoro¿3¿hidroxi¿4¿metiltetrahidrofuran¿2¿il)metoxi) (fenoxi)fosforil)amino)propanoato de (s)- isopropil cristalino
US8846882B2 (en) * 2011-04-29 2014-09-30 Synbias Pharma Ag Method of producing 4-demethoxydaunorubicin
CN104151376B (zh) * 2014-06-23 2017-02-08 天津药物研究院新药评价有限公司 一种抗肿瘤药物及其合成方法和用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3427300A (en) * 1965-11-12 1969-02-11 Merck & Co Inc Anti-inflammatory steroid 2'-acetamido-2'-deoxy-glucoside compounds
YU33730B (en) * 1967-04-18 1978-02-28 Farmaceutici Italia Process for preparing a novel antibiotic substance and salts thereof
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
US3629231A (en) * 1968-05-23 1971-12-21 Biorex Laboratories Ltd Derivatives of glycyrrhetinic acid
FI51808C (fi) * 1968-07-15 1977-04-12 Rhone Poulenc Sa Menetelmä uusien kasvainten naftaseenijohdannaisten valmistamiseksi.
GB1467383A (en) * 1974-06-12 1977-03-16 Farmaceutici Italia Daunomycin analogues
US4039663A (en) * 1975-03-19 1977-08-02 Societa' Farmaceutici Italia S.P.A. Daunomycins, process for their uses and intermediates

Also Published As

Publication number Publication date
SE447988B (sv) 1987-01-12
DE2626783C2 (de) 1985-08-14
SE8100471L (sv) 1981-01-26
NL175300C (nl) 1984-10-16
FR2355028A1 (fr) 1978-01-13
JPS532463A (en) 1978-01-11
DE2626783A1 (de) 1977-12-29
AT344899B (de) 1978-08-10
CH622529A5 (en) 1981-04-15
CA1046510A (fr) 1979-01-16
JPS6123200B2 (fr) 1986-06-04
NL930090I2 (nl) 1994-03-16
NL930090I1 (nl) 1993-10-01
ATA636377A (de) 1978-01-15
US4107423A (en) 1978-08-15
AT345461B (de) 1978-09-25
NL175300B (nl) 1984-05-16
FR2355028B3 (fr) 1979-03-02
BE842930A (fr) 1976-10-01
SE7606808L (sv) 1977-12-16
ATA450676A (de) 1977-12-15
NL7606897A (nl) 1977-12-28
GB1509875A (en) 1978-05-04

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Legal Events

Date Code Title Description
SPCF Application for supplementary protection certificate filed

Free format text: 7606808

NAL Patent in force

Ref document number: 7606808-9

SPCG Supplementary protection certificate granted

Free format text: 9490108, 910620, EXPIRES: 20010615