SE400294B - Sett att framstella ett cis-dihalogen-bis(cykloalifatisk amin)-platina-ii-komplex - Google Patents

Sett att framstella ett cis-dihalogen-bis(cykloalifatisk amin)-platina-ii-komplex

Info

Publication number
SE400294B
SE400294B SE7305075A SE7305075A SE400294B SE 400294 B SE400294 B SE 400294B SE 7305075 A SE7305075 A SE 7305075A SE 7305075 A SE7305075 A SE 7305075A SE 400294 B SE400294 B SE 400294B
Authority
SE
Sweden
Prior art keywords
cycloalifatic
platina
dihalogen
cis
bis
Prior art date
Application number
SE7305075A
Other languages
English (en)
Inventor
M L Tobe
A R Khokhar
P D M Braddock
Original Assignee
Rustenburg Platinum Mines Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rustenburg Platinum Mines Ltd filed Critical Rustenburg Platinum Mines Ltd
Publication of SE400294B publication Critical patent/SE400294B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE7305075A 1972-04-10 1973-04-10 Sett att framstella ett cis-dihalogen-bis(cykloalifatisk amin)-platina-ii-komplex SE400294B (sv)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1634972A GB1432562A (en) 1972-04-10 1972-04-10 Platinum co-ordination compounds
GB1965672 1972-04-27
GB2138872 1972-05-08
GB2992072 1972-06-26
GB4179872 1972-09-08

Publications (1)

Publication Number Publication Date
SE400294B true SE400294B (sv) 1978-03-20

Family

ID=27516172

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7305075A SE400294B (sv) 1972-04-10 1973-04-10 Sett att framstella ett cis-dihalogen-bis(cykloalifatisk amin)-platina-ii-komplex

Country Status (7)

Country Link
US (1) US3892790A (sv)
JP (1) JPS5621040B2 (sv)
DE (1) DE2318019C2 (sv)
FR (1) FR2182941B1 (sv)
GB (1) GB1432562A (sv)
NL (1) NL182200C (sv)
SE (1) SE400294B (sv)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1578323A (en) * 1976-02-26 1980-11-05 Rustenburg Platinum Mines Ltd Compositions containing platinum
GB1585103A (en) * 1976-04-06 1981-02-25 Rustenburg Platinum Mines Ltd Pharmaceutical compositions containing platinum compounds
US4255417A (en) * 1976-08-04 1981-03-10 Johnson Matthey, Inc. Platinum compounds for the irradication of skin blemishes
US4115418A (en) * 1976-09-02 1978-09-19 Government Of The United States Of America 1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
JPS6041077B2 (ja) * 1976-09-06 1985-09-13 喜徳 喜谷 1,2‐ジアミノシクロヘキサン異性体のシス白金(2)錯体
US4175133A (en) * 1977-02-18 1979-11-20 United States Of America 1,2-Diaminocyclohexane platinum (II) complexes having antineoplastic activity against L1210 leukemia
US4151185A (en) * 1977-05-02 1979-04-24 Research Corporation Complex or salt of a platinum (II) compound and a nitrogen containing polymer
US4278660A (en) * 1977-05-02 1981-07-14 Research Corporation Complex or salt of a platinum (II) compound and a nitrogen containing polymer
US4137248A (en) * 1977-08-29 1979-01-30 The United States Of America As Represented By The Department Of Health, Education And Welfare Compound, 4-carboxyphthalato(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof
DE2845371A1 (de) * 1977-10-19 1979-04-26 Johnson Matthey Co Ltd Platinkomplexverbindung, pharmazeutische stoffzusammensetzung mit einer solchen verbindung und deren anwendung
SE447385B (sv) * 1977-10-19 1986-11-10 Johnson Matthey Co Ltd Cis-koordinationsforeningar av platina
SE447902B (sv) * 1977-10-19 1986-12-22 Johnson Matthey Co Ltd Cis-koordinationsforening av platina och komposition innehallande foreningen
NL7807334A (nl) * 1978-07-06 1980-01-08 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel.
JPS5554852A (en) * 1978-10-16 1980-04-22 Tsuneji Yamamoto Raw sea urchin eggs and method of treating them
JPS55130992A (en) * 1979-03-31 1980-10-11 Yoshinori Kitani Novel platinum complex
NL8101026A (nl) * 1981-03-03 1982-10-01 Tno Platinadiamine-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiamine-complex voor de behandeling van kanker alsmede aldus verkregen gevormd geneesmiddel.
JPS5896024A (ja) * 1981-10-16 1983-06-07 リチヤ−ド・エフ・ストツケル 白金毒解毒剤
US4578491A (en) * 1982-06-28 1986-03-25 Engelhard Corporation Bis(thiocyanato)palladium(II) complexes
IT1153974B (it) * 1982-09-23 1987-01-21 Erba Farmitalia Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento
US4560782A (en) * 1982-11-19 1985-12-24 Research Corporation Anti-tumor diplatinum coordination compounds
US4533502A (en) * 1983-02-22 1985-08-06 Rochon Fernande D Platinum (II) compounds and their preparation
US4617189A (en) * 1983-04-14 1986-10-14 Stockel Richard F Use of selenium-containing compounds for negating the toxic effects of platinum compounds used in chemotherapy, and a novel selenium-containing platinum compound and use thereof as an anti-cancer medicine
EP0210291A1 (en) * 1985-07-27 1987-02-04 American Cyanamid Company Platinum complexes of antitumor agents
US4544759A (en) * 1983-07-29 1985-10-01 American Cyanamid Company Platinum complexes of antitumor agents
GB8328218D0 (en) * 1983-10-21 1983-11-23 Johnson Matthey Plc Oral compositions
HU193809B (en) * 1984-09-12 1987-12-28 Chugai Pharmaceutical Co Ltd Process for producing new platinum complexes
US4588831A (en) * 1984-11-09 1986-05-13 Natec Platinum complex compounds of substituted 5,8-dihydroxyl-1,4-naphthoquinone, and process for their production and use
ES2054778T3 (es) * 1988-01-09 1994-08-16 Asta Medica Ag Complejos de 1,2-bis (aminometil) ciclobutano-platino.
GB9502799D0 (en) 1995-02-14 1995-04-05 Johnson Matthey Plc Improvements in platinum complexes
AU1608801A (en) 1999-11-15 2001-05-30 Parker Hughes Institute Diamino platinum (ii) antitumor complexes
GB0011903D0 (en) * 2000-05-18 2000-07-05 Astrazeneca Ab Combination chemotherapy
US8173686B2 (en) 2006-11-06 2012-05-08 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168662B1 (en) 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8178564B2 (en) * 2006-11-06 2012-05-15 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168661B2 (en) * 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US20110033528A1 (en) * 2009-08-05 2011-02-10 Poniard Pharmaceuticals, Inc. Stabilized picoplatin oral dosage form
TW200916094A (en) * 2007-06-27 2009-04-16 Poniard Pharmaceuticals Inc Stabilized picoplatin dosage form
US20100260832A1 (en) * 2007-06-27 2010-10-14 Poniard Pharmaceuticals, Inc. Combination therapy for ovarian cancer
EP2178893A4 (en) * 2007-07-16 2012-09-19 Poniard Pharmaceuticals Inc ORAL FORMULATIONS FOR PICOPLATIN
CN102006875A (zh) * 2008-02-08 2011-04-06 帕纳德制药公司 吡铂和贝伐单抗治疗结直肠癌的用途
ES2609931T3 (es) 2010-06-18 2017-04-25 Myriad Genetics, Inc. Métodos y materiales para evaluar la pérdida de heterocigosidad
EP2609216B1 (en) 2010-08-24 2016-06-01 Dana-Farber Cancer Institute, Inc. Methods for predicting anti-cancer response
EP2721181B1 (en) 2011-06-17 2019-12-18 Myriad Genetics, Inc. Methods and materials for assessing allelic imbalance
BR112014015152A2 (pt) 2011-12-21 2017-07-04 Myriad Genetics Inc métodos e materiais para a avaliação da perda de heterozigosidade
CA2864481C (en) 2012-02-23 2020-07-14 The Children's Hospital Corporation Methods for predicting anti-cancer response
WO2013182645A1 (en) 2012-06-07 2013-12-12 Institut Curie Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors
US10308986B2 (en) 2013-03-14 2019-06-04 Children's Medical Center Corporation Cancer diagnosis, treatment selection and treatment
JP6625045B2 (ja) 2013-04-05 2019-12-25 ミリアド・ジェネティックス・インコーポレイテッド 相同組換え欠損を評価するための方法および材料
US11149316B2 (en) 2013-12-09 2021-10-19 Institut Curie Methods for detecting inactivation of the homologous recombination pathway (BRCA1/2) in human tumors
EP3180447B1 (en) 2014-08-15 2020-03-11 Myriad Genetics, Inc. Methods and materials for assessing homologous recombination deficiency
EP4141127A1 (en) 2021-08-30 2023-03-01 Zentrum Familiärer Brust- und Eierstockkrebs Universitätsklinik Köln Method for assessing homologous recombination deficiency in ovarian cancer cells

Also Published As

Publication number Publication date
FR2182941B1 (sv) 1976-12-31
DE2318019C2 (de) 1982-09-23
US3892790A (en) 1975-07-01
JPS5621040B2 (sv) 1981-05-16
NL7304880A (sv) 1973-10-12
DE2318019A1 (de) 1973-11-08
NL182200C (nl) 1988-02-01
JPS497224A (sv) 1974-01-22
GB1432562A (en) 1976-04-22
FR2182941A1 (sv) 1973-12-14

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