JPS55130992A - Novel platinum complex - Google Patents

Novel platinum complex

Info

Publication number
JPS55130992A
JPS55130992A JP3923379A JP3923379A JPS55130992A JP S55130992 A JPS55130992 A JP S55130992A JP 3923379 A JP3923379 A JP 3923379A JP 3923379 A JP3923379 A JP 3923379A JP S55130992 A JPS55130992 A JP S55130992A
Authority
JP
Japan
Prior art keywords
formula
diaminocyclopentane
trans
nitrate
platinum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3923379A
Other languages
Japanese (ja)
Inventor
Yoshinori Kitani
Masahide Nomichi
Kenji Inagaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP3923379A priority Critical patent/JPS55130992A/en
Publication of JPS55130992A publication Critical patent/JPS55130992A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:Diaminocyclopentane platinum (II) complexes of formula I (R1 and R2 are same halogen or nitrate or incorporate to form one of groups of formula IIWIV or when one of them is a group of formula V, the other is nitrate; the conformation of diaminocyclopentane is trans-d- or trans-l-).
EXAMPLE: cis-Dichloro(trans-l-diaminocyclopentane) platinum (II) complex.
USE: Antitumorigenic agent.
PREPARATION: In an example, the reaction of K2PtX4 (X is halogen) with cyclopentanediamine is effected in an aqueous medium to form a compound of formula I (R1=R2=X). When necessary, the product is made to react with silver nitrate or silver sulfate to convert to a compound of formula I (R1=R2=NO3 or R1 and R2 are group of formula II). Moreover, when needed, the product is treated with potassium oxalate or sodium malonate to give other compounds of formula I.
COPYRIGHT: (C)1980,JPO&Japio
JP3923379A 1979-03-31 1979-03-31 Novel platinum complex Pending JPS55130992A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3923379A JPS55130992A (en) 1979-03-31 1979-03-31 Novel platinum complex

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3923379A JPS55130992A (en) 1979-03-31 1979-03-31 Novel platinum complex

Publications (1)

Publication Number Publication Date
JPS55130992A true JPS55130992A (en) 1980-10-11

Family

ID=12547401

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3923379A Pending JPS55130992A (en) 1979-03-31 1979-03-31 Novel platinum complex

Country Status (1)

Country Link
JP (1) JPS55130992A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0098121A2 (en) * 1982-06-24 1984-01-11 Yoshinori Kidani Platinum complexes, processes for their preparation, pharmaceutical compositions containing them and their use as medicaments

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS497224A (en) * 1972-04-10 1974-01-22
JPS5331648A (en) * 1976-09-06 1978-03-25 Yoshinori Yoshitani Cissplatinum complex of 1*22diaminocyclohexane isomer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS497224A (en) * 1972-04-10 1974-01-22
JPS5331648A (en) * 1976-09-06 1978-03-25 Yoshinori Yoshitani Cissplatinum complex of 1*22diaminocyclohexane isomer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0098121A2 (en) * 1982-06-24 1984-01-11 Yoshinori Kidani Platinum complexes, processes for their preparation, pharmaceutical compositions containing them and their use as medicaments

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