SE399705B - Prostaglandinanaloger av typ e2 och f2alfa - Google Patents

Prostaglandinanaloger av typ e2 och f2alfa

Info

Publication number: SE399705B
Authority: SE; Sweden
Prior art keywords: fจ2alfa; type; prostaglandin analogues; prostaglandin; analogues
Prior art date: 1971-05-11

Application number

SE7206139A

Other languages

English (en)

Swedish (sv)

Inventor

J Bowler

N S Crossley

Original Assignee

Ici Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1971-05-11

Filing date

1972-05-09

Publication date

1978-02-27

1972-01-05 Priority claimed from GB3967272A external-priority patent/GB1348036A/en

1972-05-09 Application filed by Ici Ltd filed Critical Ici Ltd

1978-02-27 Publication of SE399705B publication Critical patent/SE399705B/xx

Links

229940006138 antiglaucoma drug and miotics prostaglandin analogues Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/42—Singly bound oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/535—Organo-phosphoranes
- C07F9/5352—Phosphoranes containing the structure P=C-

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Investigating Or Analysing Biological Materials (AREA)

SE7206139A 1971-05-11 1972-05-09 Prostaglandinanaloger av typ e2 och f2alfa SE399705B (sv)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB1413971		1971-05-11
GB3967272A GB1348036A (en)	1970-05-15	1972-01-05	Transistorized vertical deflection circuit

Publications (1)

Publication Number	Publication Date
SE399705B true SE399705B (sv)	1978-02-27

Family

ID=26235892

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
SE7206139A SE399705B (sv)	1971-05-11	1972-05-09	Prostaglandinanaloger av typ e2 och f2alfa
SE7504335A SE7504335L (xx)	1971-05-11	1975-04-15
SE7504337A SE7504337L (sv)	1971-05-11	1975-04-15	Sett att framstella prostansyraderivat.
SE7504336A SE7504336L (xx)	1971-05-11	1975-04-15

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
SE7504335A SE7504335L (xx)	1971-05-11	1975-04-15
SE7504337A SE7504337L (sv)	1971-05-11	1975-04-15	Sett att framstella prostansyraderivat.
SE7504336A SE7504336L (xx)	1971-05-11	1975-04-15

Country Status (26)

Country	Link
JP (1)	JPS5611699B1 (xx)
AR (4)	AR194952A1 (xx)
AT (4)	AT328103B (xx)
AU (1)	AU462755B2 (xx)
BE (1)	BE783292A (xx)
CA (1)	CA1077033A (xx)
CH (3)	CH590223A5 (xx)
CS (1)	CS192456B2 (xx)
DD (1)	DD99155A5 (xx)
DE (1)	DE2223365C3 (xx)
DK (1)	DK134598B (xx)
EG (1)	EG10752A (xx)
ES (1)	ES402627A1 (xx)
FI (1)	FI63221C (xx)
FR (1)	FR2137712A1 (xx)
HK (1)	HK50176A (xx)
HU (1)	HU166717B (xx)
IE (1)	IE37602B1 (xx)
IL (1)	IL39376A (xx)
KE (1)	KE2634A (xx)
NL (1)	NL164272C (xx)
NO (1)	NO139521C (xx)
SE (4)	SE399705B (xx)
SU (1)	SU662007A3 (xx)
YU (1)	YU35876B (xx)
ZM (1)	ZM8172A1 (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4304907A (en) *	1972-05-10	1981-12-08	The Upjohn Company	Bicyclo lactone intermediates for prostaglandin analogs
DD118856A5 (xx) *	1972-11-08	1976-03-20
US3968144A (en) *	1973-05-21	1976-07-06	The Upjohn Company	5-Oxa-11-deoxy phenyl- and phenoxy-substituted prostalandin E1 analogs
US3966795A (en) *	1973-05-21	1976-06-29	The Upjohn Company	5-Oxa-11-deoxyphenyl- and phenoxy-substituted prostaglandin F1.sub.α analogs
US4387241A (en) *	1974-11-01	1983-06-07	American Cyanamid Company	Novel 16-aryloxy-17,18,19,20-tetranorprostanoic acids and derivatives
US4149006A (en) *	1977-01-24	1979-04-10	G. D. Searle & Co.	Prostaglandin derivatives having alkynyl, hydroxy and aryloxy junctions in the 2β side chain
US4191774A (en) *	1978-01-18	1980-03-04	Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T.	Novel 17-aza-PGF2α derivatives and pharmaceutical compositions containing the same
US4228296A (en) *	1979-01-24	1980-10-14	American Cyanamid Company	Novel 16-aryloxy-17,18,19,20-tetranorprostanoic acids and derivatives
US4929740A (en) *	1984-10-09	1990-05-29	Syntex (U.S.A.) Inc.	Process for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives
CS264861B1 (en) *	1986-12-12	1989-09-12	Kral Josef	Agent for cow natality increase
CS265947B1 (en) *	1987-06-16	1989-11-14	Kral Josef	Means for farming animals' ovarian functions control
US5565492A (en) *	1988-07-18	1996-10-15	Alcon Laboratories, Inc.	Prostaglandin combinations in glaucoma therapy
CS276003B6 (en) *	1988-09-28	1992-03-18	Spolana	method of production of (+)-isomer of cloprostenol
US5688819A (en) *	1992-09-21	1997-11-18	Allergan	Cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5352708A (en) *	1992-09-21	1994-10-04	Allergan, Inc.	Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5510383A (en) *	1993-08-03	1996-04-23	Alcon Laboratories, Inc.	Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension
US6531504B2 (en) *	2001-05-17	2003-03-11	Allergan, Inc.	Prostanoic acid derivatives as agents for lowering intraocular pressure
CA2705150C (en) *	2007-11-09	2016-06-14	Allergan, Inc.	Substituted cyclopentanes having prostaglandin activity

1972
- 1972-04-27 IE IE557/72A patent/IE37602B1/xx unknown
- 1972-04-28 CA CA140,884A patent/CA1077033A/en not_active Expired
- 1972-05-04 HU HUIE502A patent/HU166717B/hu unknown
- 1972-05-08 ZM ZM81/72*UA patent/ZM8172A1/xx unknown
- 1972-05-08 AU AU42024/72A patent/AU462755B2/en not_active Expired
- 1972-05-08 IL IL39376A patent/IL39376A/xx unknown
- 1972-05-09 NO NO1648/72A patent/NO139521C/no unknown
- 1972-05-09 SE SE7206139A patent/SE399705B/xx unknown
- 1972-05-09 EG EG193/72A patent/EG10752A/xx active
- 1972-05-10 CH CH697472A patent/CH590223A5/xx not_active IP Right Cessation
- 1972-05-10 BE BE783292A patent/BE783292A/xx not_active IP Right Cessation
- 1972-05-10 FI FI1333/72A patent/FI63221C/fi active
- 1972-05-10 ES ES402627A patent/ES402627A1/es not_active Expired
- 1972-05-10 NL NL7206361.A patent/NL164272C/xx not_active IP Right Cessation
- 1972-05-10 CH CH1566776A patent/CH596166A5/xx not_active IP Right Cessation
- 1972-05-10 DK DK236272AA patent/DK134598B/da unknown
- 1972-05-10 CH CH1566676A patent/CH596165A5/xx not_active IP Right Cessation
- 1972-05-10 FR FR7216685A patent/FR2137712A1/fr active Granted
- 1972-05-10 SU SU721787999A patent/SU662007A3/ru active
- 1972-05-11 JP JP4684472A patent/JPS5611699B1/ja active Pending
- 1972-05-11 AR AR241955A patent/AR194952A1/es active
- 1972-05-11 CS CS723161A patent/CS192456B2/cs unknown
- 1972-05-11 DD DD162906A patent/DD99155A5/xx unknown
- 1972-05-11 YU YU1250/72A patent/YU35876B/xx unknown
- 1972-05-12 AT AT538973*7A patent/AT328103B/de not_active IP Right Cessation
- 1972-05-12 AT AT419172A patent/AT333447B/de not_active IP Right Cessation
- 1972-05-12 DE DE2223365A patent/DE2223365C3/de not_active Expired
- 1972-11-30 AR AR245419A patent/AR197101A1/es active
- 1972-11-30 AR AR245418A patent/AR197100A1/es active
- 1972-11-30 AR AR245420A patent/AR200484A1/es active
1973
- 1973-05-12 AT AT539073*7A patent/AT328104B/de not_active IP Right Cessation
- 1973-05-12 AT AT539173*7A patent/AT328105B/de not_active IP Right Cessation
1975
- 1975-04-15 SE SE7504335A patent/SE7504335L/xx unknown
- 1975-04-15 SE SE7504337A patent/SE7504337L/xx unknown
- 1975-04-15 SE SE7504336A patent/SE7504336L/xx unknown
1976
- 1976-05-31 KE KE2634*UA patent/KE2634A/xx unknown
- 1976-08-05 HK HK501/76*UA patent/HK50176A/xx unknown

Also Published As

Publication number	Publication date
AR197100A1 (es)	1974-03-15
DE2223365C3 (de)	1981-06-04
EG10752A (en)	1976-05-31
SE7504337L (sv)	1975-04-15
CH596165A5 (xx)	1978-02-28
NL164272B (nl)	1980-07-15
CH596166A5 (xx)	1978-02-28
AR200484A1 (es)	1974-11-15
AT328103B (de)	1976-03-10
SE7504336L (xx)	1975-04-15
DE2223365B2 (de)	1980-07-31
DD99155A5 (xx)	1973-07-20
ZM8172A1 (en)	1973-01-22
FI63221B (fi)	1983-01-31
AR194952A1 (es)	1973-08-30
CS192456B2 (en)	1979-08-31
ATA419172A (de)	1976-03-15
AT328105B (de)	1976-03-10
NO139521B (no)	1978-12-18
AT333447B (de)	1976-11-25
IE37602B1 (en)	1977-08-31
HU166717B (xx)	1975-05-28
BE783292A (fr)	1972-11-10
YU35876B (en)	1981-08-31
IL39376A0 (en)	1972-07-26
ATA539173A (de)	1975-05-15
KE2634A (en)	1976-06-11
ES402627A1 (es)	1975-11-01
FR2137712B1 (xx)	1976-04-16
IL39376A (en)	1975-07-28
AT328104B (de)	1976-03-10
AU462755B2 (en)	1975-07-03
YU125072A (en)	1981-02-28
CH590223A5 (xx)	1977-07-29
FI63221C (fi)	1983-05-10
DE2223365A1 (de)	1972-12-07
DK134598B (da)	1976-12-06
NO139521C (no)	1979-03-28
DK134598C (xx)	1977-05-16
SE7504335L (xx)	1975-04-15
AU4202472A (en)	1973-11-15
ATA538973A (de)	1975-05-15
FR2137712A1 (en)	1972-12-29
HK50176A (en)	1976-08-13
JPS5611699B1 (xx)	1981-03-16
NL7206361A (xx)	1972-11-14
IE37602L (en)	1972-11-11
AR197101A1 (es)	1974-03-15
CA1077033A (en)	1980-05-06
NL164272C (nl)	1980-12-15
SU662007A3 (ru)	1979-05-05
ATA539073A (de)	1975-05-15

Publication	Publication Date	Title
FI55379B (fi)	1979-03-30	Polyolefinmassa med baettre vattenavledningsegenskaper foer framstaellning av papper och massans framstaellningsfoerfarande
FI56645B (fi)	1979-11-30	Foerfarande och anordning foer framstaellning av saerskilt saosom byggnadselement anvaendbara vaeggar plattor eller formelement
SE399705B (sv)	1978-02-27	Prostaglandinanaloger av typ e2 och f2alfa
FI53568C (fi)	1978-06-12	Foerfarande och anordning foer framstaellning av planglas
IT963759B (it)	1974-01-21	Preparazione di solfuri di fluoroalcano
FI54592B (fi)	1978-09-29	Foerpackning av straengar av med adhesionsmedel belagda glasfibrer och foerfarande foer framstaellning av foerpackningen
FI54455C (fi)	1978-12-11	Baerrulle foer bandtransportoerer eller rullbanor
SE430689B (sv)	1983-12-05	Heterocykliska tioaminer for framstellning av karbamider, tiokarbamider och guanidiner
FI55153B (fi)	1979-02-28	Ledad och styrbar snoekaelke
FI54942B (fi)	1978-12-29	Foerfarande foer fibrering eller blekning av vaextaemnen
FI53790C (fi)	1978-08-10	Foerfarande och anordning foer styrd gjutning av en form med smaelt metall
FI55640B (fi)	1979-05-31	Foerfarande foer utnyttjande av suspenderat utfaellt och/eller upploest material i avloppsvattnet fraon reningsanlaeggningar foer metallurgiska smaeltugnar
FI55786C (fi)	1979-10-10	Foerfarande och anordning foer foerspaoning av avfallstrae
CH538585A (de)	1973-06-30	Saugdüse
SE389669B (sv)	1976-11-15	Forfarande for framstellning av 15-metyl eller 15-etyl-prostaglandinforeningar av typ pge
FI58361B (fi)	1980-09-30	Foerfaringssaett och anordning foer utfoerande av blekning av cellulosamassa
BE779155A (fr)	1972-08-09	Preparation d'un aminophenyl-benzothiazole
FI55144C (fi)	1979-06-11	Fordonsdaeck innefattande en radiell stomme och en topparmering
BE777967A (fr)	1972-07-13	Preparation d'ortho-chlorophenols
FI58077B (fi)	1980-08-29	Foerfarande och anordning foer mekanisk eller kemiskmekanisk behandling av vaetskor
FI55542B (fi)	1979-04-30	Foerfarande foer laminering av akryl- och polyesterhartsskivor och lossnande papper foer genomfoerande av foerfarandet
FI55979B (fi)	1979-07-31	Anordning foer fyllning och toemning av silor
FI45424C (fi)	1979-03-07	Foerfarande foer gjutning av saerpraeglade smyckesfoeremaol av metall och form foer tillaempning av foerfarandet
IT955425B (it)	1973-09-29	Preparazione di tetraisopropil tioperossidifosfato
IT956779B (it)	1973-10-10	Preparazione di 2 2 bipiridili

SE399705B - Prostaglandinanaloger av typ e2 och f2alfa - Google Patents