SE398500B - Forfarande for framstellning av 2-(3-legre alkylamino-2-hydroxipropyl)-3-fenylpyrazin - Google Patents

Forfarande for framstellning av 2-(3-legre alkylamino-2-hydroxipropyl)-3-fenylpyrazin

Info

Publication number
SE398500B
SE398500B SE7305384A SE7305384A SE398500B SE 398500 B SE398500 B SE 398500B SE 7305384 A SE7305384 A SE 7305384A SE 7305384 A SE7305384 A SE 7305384A SE 398500 B SE398500 B SE 398500B
Authority
SE
Sweden
Prior art keywords
hydroxipropyl
phenylpyrazine
leger
alkylamino
procedure
Prior art date
Application number
SE7305384A
Other languages
English (en)
Inventor
B K Wasson
L M Weinstock
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of SE398500B publication Critical patent/SE398500B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/18Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE7305384A 1972-05-05 1973-04-16 Forfarande for framstellning av 2-(3-legre alkylamino-2-hydroxipropyl)-3-fenylpyrazin SE398500B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA141,471A CA1001631A (en) 1972-05-05 1972-05-05 2-(3-substituted amino-2-hydroxy-propoxy)-3-substituted pyrazines and method for preparation

Publications (1)

Publication Number Publication Date
SE398500B true SE398500B (sv) 1977-12-27

Family

ID=4093189

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7305384A SE398500B (sv) 1972-05-05 1973-04-16 Forfarande for framstellning av 2-(3-legre alkylamino-2-hydroxipropyl)-3-fenylpyrazin

Country Status (13)

Country Link
JP (1) JPS584026B2 (sv)
AU (1) AU474809B2 (sv)
BE (1) BE799099A (sv)
CA (1) CA1001631A (sv)
CH (1) CH580603A5 (sv)
DE (1) DE2322362A1 (sv)
ES (1) ES414321A1 (sv)
FR (1) FR2183752B1 (sv)
GB (1) GB1390329A (sv)
HU (1) HU167634B (sv)
NL (1) NL7305480A (sv)
SE (1) SE398500B (sv)
ZA (1) ZA733051B (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR207133A1 (es) * 1973-02-20 1976-09-15 Ciba Geigy Ag Procedimiento para la elaboracion de derivados de 1-piridiloxi 1-pirimidiniloxi y 1-piraziniloxi-2-hidroxi-3-amino-propano
JPS5839832B2 (ja) * 1974-02-20 1983-09-01 チバ ガイギ− アクチエンゲゼルシヤフト 新規ピラジン化合物の製法
US4060601A (en) * 1976-06-15 1977-11-29 Merck & Co., Inc. Certain lower-alkyl amino-2'-hydroxy-propoxy pyridines
JP2830387B2 (ja) * 1990-06-08 1998-12-02 株式会社明電舎 タイヤ有効半径測定方法
KR0138005B1 (ko) * 1993-10-21 1998-05-15 김낙두 신규의 화학적 보호제(chemopreventive agent)및 그의 제조방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1473815A (fr) * 1962-11-16 1967-03-24 Nl Combinatie Chem Ind Procédé de préparation d'amines tertiaires et nouveaux composés ainsi obtenus

Also Published As

Publication number Publication date
AU474809B2 (en) 1976-08-05
BE799099A (fr) 1973-11-05
CH580603A5 (sv) 1976-10-15
JPS584026B2 (ja) 1983-01-24
ES414321A1 (es) 1976-02-01
AU5493973A (en) 1974-10-31
DE2322362A1 (de) 1973-11-22
GB1390329A (en) 1975-04-09
CA1001631A (en) 1976-12-14
FR2183752B1 (sv) 1976-03-05
ZA733051B (en) 1974-12-24
HU167634B (sv) 1975-11-28
NL7305480A (sv) 1973-11-07
FR2183752A1 (sv) 1973-12-21
JPS4961181A (sv) 1974-06-13

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