|
JPS5418330B2
(xx)
*
|
1973-03-16 |
1979-07-06 |
|
|
|
US3966905A
(en)
*
|
1973-05-29 |
1976-06-29 |
Barnes-Hind Pharmaceuticals, Inc. |
Stabilized catechol amine solutions
|
|
US3929989A
(en)
*
|
1974-06-14 |
1975-12-30 |
Wendt Lab Inc |
Stable suspension of calcium-magnesium oxytetracycline for intrauterine administration in treatment of bovine metritis
|
|
GB1538903A
(en)
*
|
1975-04-11 |
1979-01-24 |
Nelson Res & Dev |
Carrier for a topically applied physiologically active agent or cosmetic agent
|
|
US4018889A
(en)
*
|
1976-01-02 |
1977-04-19 |
Pfizer Inc. |
Oxytetracycline compositions
|
|
DE2602363C2
(de)
*
|
1976-01-22 |
1984-04-12 |
Bayer Ag, 5090 Leverkusen |
Wäßrige, injizierbare Niclofolan- Formulierungen
|
|
GB1592053A
(en)
*
|
1976-12-16 |
1981-07-01 |
Norbrook Lab Ltd |
Oxytetracycline compositions
|
|
US4213963A
(en)
*
|
1978-12-14 |
1980-07-22 |
Janssen Pharmaceutica N.V. |
Fluspirilene-containing compositions
|
|
US4259331A
(en)
*
|
1979-04-16 |
1981-03-31 |
Pfizer Inc. |
Oxytetracycline compositions
|
|
US4399127A
(en)
*
|
1980-04-10 |
1983-08-16 |
Diamond Shamrock Corporation |
Injectable oxytetracycline compositions
|
|
US4386083A
(en)
*
|
1980-04-10 |
1983-05-31 |
Walter Hacke |
Injectable oxytetracycline compositions
|
|
IE74244B1
(en)
*
|
1985-10-01 |
1997-07-16 |
Bimeda Res Dev Ltd |
A process for preparing an antibiotic composition
|
|
US5071643A
(en)
*
|
1986-10-17 |
1991-12-10 |
R. P. Scherer Corporation |
Solvent system enhancing the solubility of pharmaceuticals for encapsulation
|
|
US6756365B2
(en)
*
|
1991-11-06 |
2004-06-29 |
Trustees Of Tufts College |
Reducing tetracycline resistance in living cells
|
|
EP0626171A1
(de)
*
|
1993-05-26 |
1994-11-30 |
Winfried Dörnhöfer |
Injektionslösung für die intravenöse oder intramuskuläre Verabreichung an Tiere
|
|
US6383515B2
(en)
|
1999-05-28 |
2002-05-07 |
Sawyer Maryjean |
Solvent system for enhancing solubility
|
|
US8106225B2
(en)
*
|
1999-09-14 |
2012-01-31 |
Trustees Of Tufts College |
Methods of preparing substituted tetracyclines with transition metal-based chemistries
|
|
ATE523485T1
(de)
*
|
1999-09-14 |
2011-09-15 |
Tufts College |
Verfahren zur herstellung von substituierten tetracyclinen mit hilfe von auf übergangsmetalle basierten chemikalien
|
|
US6849615B2
(en)
|
1999-09-14 |
2005-02-01 |
Paratek Pharmaceuticals, Inc. |
13-substituted methacycline compounds
|
|
US6500812B2
(en)
|
1999-09-14 |
2002-12-31 |
Paratek Pharmaceuticals, Inc. |
13-substituted methacycline compounds
|
|
CA2397863A1
(en)
*
|
2000-01-24 |
2001-07-26 |
Trustees Of Tufts College |
Tetracycline compounds for treatment of cryptosporidium parvum related disorders
|
|
AU2001251157A1
(en)
*
|
2000-03-31 |
2001-10-15 |
Paratek Pharmaceuticals, Inc |
7-and 9-carbamate, urea, thiourea, thiocarbamate, and heteroaryl-amino substituted tetracycline compounds
|
|
CA2409063A1
(en)
*
|
2000-05-15 |
2001-11-22 |
Mark L. Nelson |
7-substituted fused ring tetracycline compounds
|
|
US20020128238A1
(en)
*
|
2000-06-16 |
2002-09-12 |
Nelson Mark L. |
7-phenyl-substituted tetracycline compounds
|
|
US20020132798A1
(en)
*
|
2000-06-16 |
2002-09-19 |
Nelson Mark L. |
7-phenyl-substituted tetracycline compounds
|
|
US20040224927A1
(en)
*
|
2000-06-16 |
2004-11-11 |
Trustees Of Tufts College |
7-N-substituted phenyl tetracycline compounds
|
|
CA2415086A1
(en)
|
2000-07-07 |
2002-01-17 |
Trustees Of Tufts College |
7,8 and 9-substituted tetracycline compounds
|
|
US20050143353A1
(en)
*
|
2000-07-07 |
2005-06-30 |
Paratek Pharmaceuticals, Inc. |
13-Substituted methacycline compounds
|
|
HUP0301163A3
(en)
|
2000-07-07 |
2008-08-28 |
Tufts College |
7-substituted tetracycline dervatives, pharmaceutical compositions containing them and their use
|
|
US7094806B2
(en)
|
2000-07-07 |
2006-08-22 |
Trustees Of Tufts College |
7, 8 and 9-substituted tetracycline compounds
|
|
EP1301467B1
(en)
|
2000-07-07 |
2006-08-16 |
Trustees Of Tufts College |
9-substituted minocycline compounds
|
|
CN1452611A
(zh)
|
2000-07-07 |
2003-10-29 |
塔夫茨大学信托人 |
13－取代甲烯土霉素化合物
|
|
DE60135387D1
(de)
|
2001-03-13 |
2008-09-25 |
Paratek Pharm Innc |
7,9 substituierte tetracyclinverbindungen
|
|
WO2002072506A2
(en)
*
|
2001-03-13 |
2002-09-19 |
Paratek Pharmaceuticals, Inc. |
7-pyrollyl tetracycline compounds and methods of use thereof
|
|
CA2440757A1
(en)
|
2001-03-14 |
2002-09-19 |
Michael Draper |
Substituted tetracycline compounds as synergistic antifungal agents
|
|
WO2002072022A2
(en)
*
|
2001-03-14 |
2002-09-19 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds as antifungal agents
|
|
EP2186793A1
(en)
|
2001-04-24 |
2010-05-19 |
Paratek Pharmaceuticals, Inc. |
Substituted Tetracycline Compounds
|
|
US8088820B2
(en)
*
|
2001-04-24 |
2012-01-03 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for the treatment of malaria
|
|
JP2005514410A
(ja)
|
2002-01-08 |
2005-05-19 |
パラテック ファーマシューティカルズ インコーポレイテッド |
４−デジメチルアミノテトラサイクリン化合物
|
|
KR101163937B1
(ko)
|
2002-03-08 |
2012-07-09 |
파라테크 파마슈티컬스, 인크. |
아미노-메틸 치환된 테트라시클린 화합물
|
|
JP2005520846A
(ja)
|
2002-03-21 |
2005-07-14 |
パラテック ファーマシューティカルズ インコーポレイテッド |
置換されたテトラサイクリン化合物。
|
|
EP1534300A4
(en)
|
2002-07-12 |
2008-04-23 |
Paratek Pharm Innc |
TETRACYCLINE COMPOUNDS SUBSTITUTED IN 3, 10, AND 12A
|
|
CA2502464A1
(en)
|
2002-10-24 |
2004-05-06 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for the treatment of malaria
|
|
AU2003261633A1
(en)
*
|
2003-02-12 |
2004-09-06 |
R And P Korea Co., Ltd. |
Solvent system of hardly soluble drug with improved elution rate
|
|
WO2005009944A1
(en)
|
2003-07-09 |
2005-02-03 |
Paratek Pharmaceuticals, Inc. |
Prodrugs of 9-aminomethyl tetracycline compounds
|
|
US20060287283A1
(en)
*
|
2003-07-09 |
2006-12-21 |
Paratek Pharmaceuticals, Inc. |
Prodrugs of 9-aminomethyl tetracycline compounds
|
|
EA201100956A1
(ru)
|
2003-07-09 |
2012-01-30 |
Пэрэтек Фамэсьютикэлс, Инк. |
Замещенные соединения тетрациклина (варианты), фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния у субъекта
|
|
EP2332904A3
(en)
|
2004-01-15 |
2012-04-11 |
Paratek Pharmaceuticals, Inc. |
Derivatives of tetracycline compounds
|
|
TWI261038B
(en)
*
|
2004-08-11 |
2006-09-01 |
Bo-Cheng Chen |
Bicycle gear-shifting handgrip
|
|
EP2284156A3
(en)
|
2004-10-25 |
2011-09-21 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds
|
|
EP1805134B1
(en)
*
|
2004-10-25 |
2012-06-20 |
Paratek Pharmaceuticals, Inc. |
4-aminotetracyclines and methods of use thereof
|
|
AU2006210406C1
(en)
*
|
2005-02-04 |
2013-03-07 |
Paratek Pharmaceuticals, Inc. |
11a, 12-derivatives of tetracycline compounds
|
|
DE102005012595A1
(de)
*
|
2005-03-18 |
2006-09-21 |
Lanxess Deutschland Gmbh |
Herstellung von Tri(chlorpropyl)phosphat
|
|
CA2616224A1
(en)
*
|
2005-07-21 |
2007-02-01 |
Paratek Pharmaceuticals, Inc. |
10-substituted tetracyclines and methods of use thereof
|
|
JP2009508951A
(ja)
*
|
2005-09-19 |
2009-03-05 |
アルベマール・コーポレーシヨン |
カリウムイブプロフェンの極めて濃厚な注入可能な水溶液、その製造法および使用
|
|
EP2298324A1
(en)
|
2006-01-24 |
2011-03-23 |
Paratek Pharmaceuticals, Inc. |
Methods of increasing oral bioavailability of tetracyclines
|
|
EP2007713A2
(en)
*
|
2006-04-17 |
2008-12-31 |
Teva Pharmaceutical Industries Ltd |
Isolation of tetracycline derivatives
|
|
US8198470B2
(en)
*
|
2006-04-24 |
2012-06-12 |
Teva Pharmaceutical Industries Ltd. |
Crystalline form II of tigecycline and processes for preparation thereof
|
|
US7871993B2
(en)
*
|
2006-04-24 |
2011-01-18 |
Teva Pharmaceutical Industries Ltd. |
Tigecycline crystalline forms and processes for preparation thereof
|
|
WO2007133797A2
(en)
*
|
2006-05-15 |
2007-11-22 |
Paratek Pharmaceuticals, Inc. |
Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
|
|
US8440646B1
(en)
|
2006-10-11 |
2013-05-14 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for treatment of Bacillus anthracis infections
|
|
BRPI0720569B8
(pt)
|
2006-12-21 |
2021-05-25 |
Paratek Pharm Innc |
compostos de tetraciclina substituída e uso dos ditos compostos para o tratamento de uma infecção bacteriana, viral ou parasitária
|
|
AU2007338681B2
(en)
|
2006-12-21 |
2013-09-26 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for treatment of inflammatory skin disorders
|
|
WO2008127722A1
(en)
*
|
2007-04-12 |
2008-10-23 |
Paratek Pharmaceuticals, Inc. |
Methods for treating spinal muscular atrophy using tetracycline compounds
|
|
EP2216323A3
(en)
|
2007-04-27 |
2010-12-29 |
Paratek Pharmaceuticals, Inc. |
Methods for synthesizing and purifying aminoalkyl tetracycline compounds
|
|
ATE555079T1
(de)
|
2007-07-06 |
2012-05-15 |
Paratek Pharm Innc |
Verfahren zur synthese von 9-substituiertem minocyclin
|
|
EP2262754A4
(en)
*
|
2008-03-05 |
2012-03-14 |
Paratek Pharm Innc |
MINOCYCLINE COMPOUNDS AND METHODS OF USE THEREOF
|
|
PT2271348T
(pt)
|
2008-03-28 |
2018-04-16 |
Paratek Pharm Innc |
Formulação de comprimido oral de composto de tetraciclina
|
|
EP2276342A4
(en)
*
|
2008-04-14 |
2012-02-22 |
Paratek Pharm Innc |
SUBSTITUTED TETRACYCLIN COMPOUNDS
|
|
TW202021946A
(zh)
|
2008-05-23 |
2020-06-16 |
美商派洛泰克藥物股份有限公司 |
四環素化合物之甲苯磺酸鹽及同素異形體
|
|
MX337488B
(es)
|
2008-07-21 |
2016-03-08 |
Si Group Inc |
Granulos con alto contenido de ibuprofeno sodico, su preparacion y su uso en preparar formas de dosificacion solidas no efervescentes.
|
|
US9629809B2
(en)
|
2008-07-21 |
2017-04-25 |
Si Group, Inc. |
High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
|
|
KR20110081197A
(ko)
*
|
2008-09-19 |
2011-07-13 |
파라테크 파마슈티컬스, 인크. |
류마티스 관절염의 치료를 위한 테트라시클린 화합물 및 관련된 치료 방법
|
|
US20120121706A1
(en)
|
2009-04-10 |
2012-05-17 |
Tufts Medical Center, Inc. |
PAR-1 Activation by Metalloproteinase-1 (MMP-1)
|
|
PT2707003T
(pt)
|
2011-05-12 |
2019-08-05 |
Paratek Pharm Innc |
Sais cristalinos da amida do ácido (4s,4as,5ar,12as)-4-dimetilamino-3,10,12,12a-tetra-hidroxi-7-[(metoxi(metil)amino]-metil]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octa-hidro-naftaceno-2-carboxílico e métodos de utilização dos mesmos
|
|
SG10201913599RA
(en)
|
2016-11-01 |
2020-02-27 |
Paratek Pharm Innc |
9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (cabp)
|
|
BR112020000968A2
(pt)
|
2017-07-21 |
2020-07-14 |
Almirall, Llc |
tratamento de lesões não inflamatórias
|