RU95114532A - Устройство для распыления лекарственного средства в форме порошка - Google Patents

Устройство для распыления лекарственного средства в форме порошка

Info

Publication number
RU95114532A
RU95114532A RU95114532/14A RU95114532A RU95114532A RU 95114532 A RU95114532 A RU 95114532A RU 95114532/14 A RU95114532/14 A RU 95114532/14A RU 95114532 A RU95114532 A RU 95114532A RU 95114532 A RU95114532 A RU 95114532A
Authority
RU
Russia
Prior art keywords
chamber
impeller
spray chamber
housing
wall
Prior art date
Application number
RU95114532/14A
Other languages
English (en)
Other versions
RU2141849C1 (ru
Inventor
Бернард Мекикалски Марк
Ричард Вильямс Дэвид
Орел Тьюсан Дэвид
Original Assignee
Дьюра Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Дьюра Фармасьютикалз, Инк. filed Critical Дьюра Фармасьютикалз, Инк.
Priority claimed from PCT/US1993/009751 external-priority patent/WO1994008552A2/en
Publication of RU95114532A publication Critical patent/RU95114532A/ru
Application granted granted Critical
Publication of RU2141849C1 publication Critical patent/RU2141849C1/ru

Links

Claims (11)

1. Устройство для распыления лекарственного средства в форме порошка, включающее корпус, отличающееся тем, что содержит в общем плоскую переднюю стенку камеры, в общем плоскую заднюю стенку камеры и круговую стенку камеры, расположенные в корпусе и образующие в общем дисковидной формы распылительную камеру, крыльчатку, установленную в распылительной камере и вращающуюся в плоскости, в общем параллельной передней и задней стенкам камеры, двигатель, соединенный с крыльчаткой и предназначенный для вращения крыльчатки в распылительной камере, и по меньшей мере одно впускное отверстие и по меньшей мере одно выпускное отверстие в распылительной камере.
2. Устройство по п. 1, отличающееся тем, что передняя стенка камеры отделена от задней стенки камеры расстоянием, меньшим чем один диаметр крыльчатки.
3. Устройство по п. 1, отличающееся тем, что к корпусу, включая переднюю стенку камеры, может крепиться мундштук.
4. Устройство по п. 1 или 2, отличающееся тем, что выпускное отверстие располагается рядом с круговой стенкой камеры.
5. Устройство по п. 1 или 2, отличающееся тем, что крыльчатка имеет диаметр, приблизительно в четыре раза превышающий расстояние между передней и задней стенками камеры.
6. Устройство по п. 1 или 2, отличающееся тем, что двигатель расположен вне распылительной камеры.
7. Устройство по п. 1, отличающееся тем, что содержит средства для подачи порошка в распылительную камеру.
8. Устройство по п. 1 или 2, отличающееся тем, что содержит также передний цилиндр, прикрепленный к корпусу и включающий цилиндрическую камеру, первое множество отверстий, соединяющих распылительную камеру и цилиндрическую камеру, и второе множество отверстий, направленных в радиальном направлении от переднего цилиндра.
9. Устройство по п. 1 или 2, отличающееся тем, что содержит однопутевый клапан для предупреждения выдыхания в устройство.
10. Устройство по п. 9, отличающееся тем, что содержит переключатель, включающий двигатель при открывании однопутевого клапана.
11. Устройство по пп. 1, 2 или 5, отличающееся тем, что крыльчатка плотно входит в распылительную камеру со всех сторон.
RU95114532A 1992-10-19 1993-10-12 Устройство для распыления лекарственного средства в форме порошка RU2141849C1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US96340992A 1992-10-19 1992-10-19
US07/963409 1992-10-19
US07/963,409 1992-10-19
PCT/US1993/009751 WO1994008552A2 (en) 1992-10-19 1993-10-12 Dry powder inhaler

Publications (2)

Publication Number Publication Date
RU95114532A true RU95114532A (ru) 1997-07-27
RU2141849C1 RU2141849C1 (ru) 1999-11-27

Family

ID=25507205

Family Applications (1)

Application Number Title Priority Date Filing Date
RU95114532A RU2141849C1 (ru) 1992-10-19 1993-10-12 Устройство для распыления лекарственного средства в форме порошка

Country Status (26)

Country Link
US (1) US5577497A (ru)
EP (1) EP0665759B1 (ru)
JP (1) JP2912453B2 (ru)
KR (1) KR0177265B1 (ru)
AT (1) ATE174804T1 (ru)
AU (1) AU679700B2 (ru)
BG (1) BG61554B1 (ru)
BR (1) BR9307270A (ru)
CA (1) CA2147260C (ru)
CZ (1) CZ282964B6 (ru)
DE (1) DE69322789T2 (ru)
DK (1) DK0665759T3 (ru)
ES (1) ES2127837T3 (ru)
FI (1) FI951838A (ru)
GR (1) GR3029732T3 (ru)
HK (1) HK1013262A1 (ru)
HU (1) HU217917B (ru)
NO (1) NO311870B1 (ru)
NZ (1) NZ257056A (ru)
PL (1) PL172758B1 (ru)
RO (1) RO113214B1 (ru)
RU (1) RU2141849C1 (ru)
SK (2) SK279327B6 (ru)
TW (1) TW235245B (ru)
UA (1) UA27938C2 (ru)
WO (1) WO1994008552A2 (ru)

Families Citing this family (214)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK280967B6 (sk) * 1990-03-02 2000-10-09 Glaxo Group Limited Inhalačný prístroj
YU48707B (sh) * 1990-03-02 1999-07-28 Glaxo Group Limited Aparat za inhaliranje - inhalator
US6055980A (en) * 1991-05-20 2000-05-02 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5785049A (en) * 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
US6586006B2 (en) 1994-08-04 2003-07-01 Elan Drug Delivery Limited Solid delivery systems for controlled release of molecules incorporated therein and methods of making same
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
AU697676B2 (en) * 1994-09-21 1998-10-15 Nektar Therapeutics Apparatus and methods for dispersing dry powder medicaments
US5780014A (en) * 1995-04-14 1998-07-14 Inhale Therapeutic Systems Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin
US5645051A (en) * 1995-04-21 1997-07-08 Dura Pharmaceuticals, Inc. Unit dose dry powder inhaler
US5622166A (en) * 1995-04-24 1997-04-22 Dura Pharmaceuticals, Inc. Dry powder inhaler delivery system
US5921237A (en) * 1995-04-24 1999-07-13 Dura Pharmaceuticals, Inc. Dry powder inhaler
US6428771B1 (en) * 1995-05-15 2002-08-06 Pharmaceutical Discovery Corporation Method for drug delivery to the pulmonary system
US5669973A (en) * 1995-06-06 1997-09-23 David Sarnoff Research Center, Inc. Apparatus for electrostatically depositing and retaining materials upon a substrate
US5714007A (en) * 1995-06-06 1998-02-03 David Sarnoff Research Center, Inc. Apparatus for electrostatically depositing a medicament powder upon predefined regions of a substrate
US20040237961A1 (en) * 1995-06-08 2004-12-02 Snow John Medlin Inhalation actuated device for use with metered dose inhalers (MDIs)
US6672304B1 (en) 1995-06-08 2004-01-06 Innovative Devices, Llc Inhalation actuated device for use with metered dose inhalers (MDIs)
DE19523516C1 (de) * 1995-06-30 1996-10-31 Asta Medica Ag Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen
US5642727A (en) * 1995-07-25 1997-07-01 David Sarnoff Research Center, Inc. Inhaler apparatus using a tribo-electric charging technique
US5875776A (en) * 1996-04-09 1999-03-02 Vivorx Pharmaceuticals, Inc. Dry powder inhaler
CA2252814A1 (en) * 1996-04-29 1997-11-06 Dura Pharmaceuticals, Inc. Methods of dry powder inhalation
US5871010A (en) * 1996-06-10 1999-02-16 Sarnoff Corporation Inhaler apparatus with modified surfaces for enhanced release of dry powders
US5857456A (en) * 1996-06-10 1999-01-12 Sarnoff Corporation Inhaler apparatus with an electronic means for enhanced release of dry powders
US5794613A (en) * 1997-01-09 1998-08-18 Sepracor, Inc. Multiple-dose dispenser for dry powder inhalers
TW469832U (en) 1997-03-14 2001-12-21 Astra Ab Inhalation device
SE9700937D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler I
US6006747A (en) 1997-03-20 1999-12-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
NZ504021A (en) * 1997-10-17 2003-04-29 Systemic Pulmonary Delivery Lt Method and apparatus for delivering aerosolized medication having air discharged through air tube directly into plume of aerosolized medication
DE69840876D1 (de) 1997-12-02 2009-07-16 Valois Sas Trockenpulverinhalator
US6116238A (en) * 1997-12-02 2000-09-12 Dura Pharmaceuticals, Inc. Dry powder inhaler
US6237591B1 (en) 1998-11-02 2001-05-29 Dura Pharmaceuticals, Inc. Turbine dry powder inhaler
US6192876B1 (en) 1997-12-12 2001-02-27 Astra Aktiebolag Inhalation apparatus and method
US6352722B1 (en) 1997-12-23 2002-03-05 Quadrant Holdings Cambridge Limited Derivatized carbohydrates, compositions comprised thereof and methods of use thereof
US6004268A (en) * 1998-04-21 1999-12-21 Addington; W. Robert Aspiration screening process for assessing post surgery patient's risk for pneumonia
US6257233B1 (en) 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
US6149774A (en) 1998-06-10 2000-11-21 Delsys Pharmaceutical Corporation AC waveforms biasing for bead manipulating chucks
SE512386C2 (sv) * 1998-07-30 2000-03-06 Microdrug Ag Förfarande och anordning för klassificering av elektrostatiskt laddat pulverformigt material
UA73924C2 (en) 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
FR2787031B1 (fr) * 1998-12-11 2001-03-30 Valois Sa Dispositif d'inhalation ameliore
CA2356637C (en) 1998-12-22 2011-09-13 The University Of North Carolina At Chapel Hill Compounds and methods for the treatment of airway diseases and for the delivery of airway drugs
US6923979B2 (en) * 1999-04-27 2005-08-02 Microdose Technologies, Inc. Method for depositing particles onto a substrate using an alternating electric field
EP1196430B1 (en) * 1999-06-29 2012-02-15 MannKind Corporation Purification and stabilization of peptide and protein pharmaceutical agents
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US7464706B2 (en) 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US6679256B2 (en) 1999-12-17 2004-01-20 Nektar Therapeutics Systems and methods for extracting powders from receptacles
US6651655B1 (en) * 2000-01-18 2003-11-25 Quadrant Technologies Limited Inhaled vaccines
DE60133723T2 (de) 2000-02-28 2009-07-02 PharmaKodex Ltd., Chippenham Verabreichungssystemen für oral anzuwendende arzneimittel
US20040115133A1 (en) * 2000-05-10 2004-06-17 Wermeling Daniel P. Intranasal opioid compositions
US20060083691A1 (en) * 2000-05-10 2006-04-20 Wermeling Daniel P Intranasal opioid compositions, delivery devices and methods of using same
MXPA02001323A (es) 2000-05-10 2004-07-16 Alliance Pharma Microgranulos con base fosfolipida para la liberacion de farmaco.
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US6610271B2 (en) * 2000-05-10 2003-08-26 University Of Kentucky Research Foundation System and method for intranasal administration of lorazepam
US20030003057A1 (en) * 2000-07-07 2003-01-02 Jeffry Weers Methods for administering leuprolide by inhalation
US6948494B1 (en) * 2000-05-10 2005-09-27 Innovative Devices, Llc. Medicament container with same side airflow inlet and outlet and method of use
AR028746A1 (es) * 2000-06-23 2003-05-21 Norton Health Care Ltd Cartucho de dosis previamente medidas para inhalador de polvo seco accionado por la respiracion, el inhalador y un metodo de provision de dosis previamente medidas de polvo seco
US7288390B2 (en) 2000-08-07 2007-10-30 Centocor, Inc. Anti-dual integrin antibodies, compositions, methods and uses
UA81743C2 (ru) 2000-08-07 2008-02-11 Центокор, Инк. МОНОКЛОНАЛЬНОЕ АНТИТЕЛО ЧЕЛОВЕКА, КОТОРОЕ СПЕЦИФИЧЕСКИ СВЯЗЫВАЕТСЯ С ФАКТОРОМ НЕКРОЗА ОПУХОЛЕЙ АЛЬФА (ФНПα), ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, КОТОРАЯ ЕГО СОДЕРЖИТ, И СПОСОБ ЛЕЧЕНИЯ РЕВМАТОИДНОГО АРТРИТА
US6902734B2 (en) 2000-08-07 2005-06-07 Centocor, Inc. Anti-IL-12 antibodies and compositions thereof
WO2002013897A2 (en) 2000-08-14 2002-02-21 Advanced Inhalation Research, Inc. Inhalation device and method
EP1315533A4 (en) * 2000-08-15 2007-06-27 Univ Kentucky Res Found PROGRAMMABLE MULTI-DOSE DEVICE FOR INTRANASAL MEDICINE ADMINISTRATION
US20040176359A1 (en) * 2001-02-20 2004-09-09 University Of Kentucky Research Foundation Intranasal Benzodiazepine compositions
US6766799B2 (en) 2001-04-16 2004-07-27 Advanced Inhalation Research, Inc. Inhalation device
WO2002092154A1 (en) 2001-04-26 2002-11-21 New England Pharmaceuticals, Inc. Metered dose delivery device for liquid and powder agents
FI20011317A0 (fi) * 2001-06-20 2001-06-20 Orion Corp Jauheinhalaattori
JP3619176B2 (ja) * 2001-09-14 2005-02-09 オムロンヘルスケア株式会社 エアロゾル粒子分別装置及び吸入器
JP4261351B2 (ja) * 2001-09-19 2009-04-30 アドヴェント ファーマセウティカルズ プロプライエタリー リミテッド 吸入器
EP1450885B1 (en) 2001-09-28 2015-04-22 Kurve Technology, Inc. Nasal nebulizer
JP2007528691A (ja) 2001-11-14 2007-10-18 セントカー・インコーポレーテツド 抗ｉｌ−６抗体、組成物、方法および使用
ATE508735T1 (de) 2001-12-19 2011-05-15 Novartis Ag Pulmonale verabreichung von aminoglykosiden
US6929798B2 (en) 2002-02-13 2005-08-16 Immunology Laboratories, Inc. Compositions and methods for treatment of microbial infections
ES2425392T3 (es) 2002-03-20 2013-10-15 Mannkind Corporation Cartucho para un aparato de inhalación
DE60302454T2 (de) * 2002-04-19 2006-08-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Beta-agonisten-verbindungen mit stickoxid-donatoren-gruppen und reaktionsfähige sauerstoffspezies-fängergruppen und ihre verwendung bei der behandlung von atemwegsstörungen
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
AU2003249623A1 (en) * 2002-05-09 2003-12-12 Kurve Technology, Inc. Particle dispersion chamber for nasal nebulizer
US7677411B2 (en) 2002-05-10 2010-03-16 Oriel Therapeutics, Inc. Apparatus, systems and related methods for processing, dispensing and/or evaluatingl dry powders
US7118010B2 (en) * 2002-05-10 2006-10-10 Oriel Therapeutics, Inc. Apparatus, systems and related methods for dispensing and /or evaluating dry powders
US6889690B2 (en) 2002-05-10 2005-05-10 Oriel Therapeutics, Inc. Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages
US6985798B2 (en) * 2002-05-10 2006-01-10 Oriel Therapeutics, Inc. Dry powder dose filling systems and related methods
SI1534366T1 (sl) 2002-06-27 2014-04-30 Oriel Therapeutics, Inc. Sistem za polnjenje doze s suhim praškom in ustrezni postopek
AU2003280130B2 (en) 2002-06-28 2009-06-11 Centocor, Inc. Mammalian CH1 deleted mimetibodies, compositions, methods and uses
EP1562975A2 (en) * 2002-10-25 2005-08-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments
US7708014B2 (en) * 2002-12-13 2010-05-04 Otsuka Pharmaceutical Co., Ltd. Inhalation device for transpulmonary administration
GB0303870D0 (en) * 2003-02-20 2003-03-26 Norton Healthcare Ltd Pre-metered dose magazine for breath-actuated dry powder inhaler
CA2534682C (en) 2003-08-18 2013-02-26 Parion Sciences, Inc. Capped pyrazinoylguanidine sodium channel blockers
EP1673123A2 (en) * 2003-09-05 2006-06-28 Kurve Technology, Inc. Integrated nebulizer and particle dispersing chamber for delivery of medicament
US20070131230A1 (en) * 2003-09-05 2007-06-14 Kurve Technology, Inc. Nasal adapter for the base of the nose
UA89481C2 (ru) 2003-09-30 2010-02-10 Центокор, Инк. Эритропоэтиновые миметические шарнирно-сердцевинные миметитела человека, композиции, способы и применение
JP2007533634A (ja) * 2003-09-30 2007-11-22 アキュスフィア， インコーポレイテッド 注射、経口、または局所用の徐放性医薬製剤
US7377277B2 (en) 2003-10-27 2008-05-27 Oriel Therapeutics, Inc. Blister packages with frames and associated methods of fabricating dry powder drug containment systems
US7338171B2 (en) * 2003-10-27 2008-03-04 Jen-Chuen Hsieh Method and apparatus for visual drive control
US7451761B2 (en) 2003-10-27 2008-11-18 Oriel Therapeutics, Inc. Dry powder inhalers, related blister package indexing and opening mechanisms, and associated methods of dispensing dry powder substances
WO2005040163A1 (en) 2003-10-28 2005-05-06 Dr. Reddy's Laboratories Ltd Heterocyclic compounds that block the effects of advanced glycation end products (age)
NZ548980A (en) * 2004-01-12 2009-10-30 Mannkind Corp Reducing serum proinsulin levels in type 2 diabetics
GB0400804D0 (en) 2004-01-14 2004-02-18 Innoscience Technology Bv Pharmaceutical compositions
US7607435B2 (en) * 2004-01-21 2009-10-27 Battelle Memorial Institute Gas or liquid flow sensor
US7491194B1 (en) 2004-02-03 2009-02-17 David Oliwa Remote control valve for urine collection bag
US20080090753A1 (en) 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
CA2563379A1 (en) 2004-03-31 2005-10-20 Centocor, Inc. Human glp-1 mimetibodies, compositions, methods and uses
CN101090714A (zh) * 2004-07-26 2007-12-19 康泽里克斯公司 通过吸入伊洛前列素和微粒制剂治疗肺动脉高血压症
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
PL1791542T3 (pl) 2004-08-23 2015-11-30 Mannkind Corp Sole diketopiperazyny do dostarczania leków
US7393662B2 (en) 2004-09-03 2008-07-01 Centocor, Inc. Human EPO mimetic hinge core mimetibodies, compositions, methods and uses
GB0427856D0 (en) 2004-12-20 2005-01-19 Glaxo Group Ltd Maniflod for use in medicament dispenser
GB0427858D0 (en) 2004-12-20 2005-01-19 Glaxo Group Ltd Manifold for use in medicament dispenser
ATE392251T1 (de) 2004-12-23 2008-05-15 Kinematica Ag Vorrichtung zum dispergieren eines festen, flüssigen oder gasförmigen stoffes in einer flüssigkeit
PE20061324A1 (es) 2005-04-29 2007-01-15 Centocor Inc Anticuerpos anti-il-6, composiciones, metodos y usos
TR201902033T4 (tr) 2005-06-30 2019-03-21 Janssen Biotech Inc Anti-IL-23 antikorları, bileşimleri, yöntemleri ve kullanımları.
AU2006290870B2 (en) 2005-09-14 2013-02-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
US8084420B2 (en) 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
US7713929B2 (en) 2006-04-12 2010-05-11 Biodel Inc. Rapid acting and long acting insulin combination formulations
US20070086952A1 (en) * 2005-09-29 2007-04-19 Biodel, Inc. Rapid Acting and Prolonged Acting Inhalable Insulin Preparations
AR058289A1 (es) 2005-12-12 2008-01-30 Glaxo Group Ltd Colector para ser usado en dispensador de medicamento
EP1973523A2 (en) * 2005-12-15 2008-10-01 Acusphere, Inc. Processes for making particle-based pharmaceutical formulations for pulmonary or nasal administration
MX2008008621A (es) 2005-12-29 2008-11-27 Centocor Inc Anticuerpos anti-il-23 humanos, composiciones, metodos y usos.
EP2497484A3 (en) 2006-02-22 2012-11-07 MannKind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
US8962643B2 (en) 2006-02-24 2015-02-24 Rigel Pharmaceuticals, Inc. Compositions and methods for inhibition of the JAK pathway
US8037880B2 (en) * 2006-04-07 2011-10-18 The University Of Western Ontario Dry powder inhaler
DE102006016904A1 (de) * 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
DE102006016901A1 (de) * 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Mundstück für einen Inhalator
MX2008013165A (es) 2006-04-12 2009-01-29 Biodel Inc Formulaciones de combinacion de insulina de accion rapida y accion larga.
DK2068889T3 (da) 2006-08-10 2020-02-03 Roy C Levitt Anakinra til anvendelse i behandling af bronchiolitis obliterans syndrom
WO2008028092A2 (en) 2006-08-30 2008-03-06 Kurve Technology, Inc. Aerosol generating and delivery device
UY30820A1 (es) 2006-12-21 2008-07-03 Centocor Inc Uso de agonistas del receptor de glp-1 de accion prolongada para mejorar la sensibilidad a la insulina y los perfiles lipidicos
US20080275030A1 (en) 2007-01-19 2008-11-06 Sveinbjorn Gizurarson Methods and Compositions for the Delivery of a Therapeutic Agent
WO2008156586A2 (en) 2007-06-12 2008-12-24 Alkermes, Inc. Inhalation device for powdered substances
US8785396B2 (en) 2007-10-24 2014-07-22 Mannkind Corporation Method and composition for treating migraines
CN101951913A (zh) 2008-02-26 2011-01-19 帕里昂科学公司 聚芳族钠通道阻断剂
CN102014973A (zh) 2008-02-29 2011-04-13 弗罗桑医疗设备公司 用于促进止血和/或伤口愈合的装置
KR101541209B1 (ko) * 2008-03-27 2015-07-31 맨카인드 코포레이션 건조 분말 흡입 시스템
DK2570147T3 (da) 2008-06-13 2018-01-29 Mannkind Corp Tørpulverinhalator og system til lægemiddelindgivelse
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
KR101628410B1 (ko) 2008-06-20 2016-06-08 맨카인드 코포레이션 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법
US8517009B2 (en) * 2008-07-13 2013-08-27 Map Pharmaceuticals, Inc. Methods and apparatus for delivering aerosolized medication
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
NZ590816A (en) 2008-08-14 2013-02-22 Cephalon Australia Pty Ltd Anti-il-12/il-23 antibodies
PL2356269T3 (pl) 2008-10-31 2016-12-30 Kompozycje białek rusztowania oparte na domenie fibronektyny typu III, sposoby i zastosowania
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
DK2389372T3 (en) 2009-01-23 2015-12-14 Rigel Pharmaceuticals Inc COMPOSITIONS AND METHODS FOR INHIBITION OF JAK pathway
CN102596992B (zh) 2009-02-12 2015-09-09 詹森生物科技公司 基于ⅲ型纤连蛋白结构域的支架组合物、方法及用途
CN102395398B (zh) 2009-02-23 2016-03-16 日本烟草产业株式会社 非加热型烟草香味吸取器
US9060927B2 (en) 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
PT2411521E (pt) 2009-03-25 2015-04-21 Univ Texas Composições para estimulação de resistência imunitária inata de mamíferos contra patogénicos
FR2946537B1 (fr) * 2009-06-11 2012-08-03 Valois Sas Dispositif d'inhalation de poudre
US8734845B2 (en) 2009-06-12 2014-05-27 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
GB2489383A (en) 2009-12-30 2012-09-26 Vijayan Thirumalai Anandampillai An improved dry powder inhaler
JP2013518097A (ja) 2010-01-26 2013-05-20 イッサム リサーチ ディヴェロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム エルティーディー 肺高血圧を予防および治療するための組成物および方法
AU2011215900A1 (en) 2010-02-10 2012-07-26 Immunogen, Inc. CD20 antibodies and uses thereof
KR101834026B1 (ko) 2010-06-19 2018-03-02 메모리얼 슬로안-케터링 캔서 센터 항-ｇｄ2 항체
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
MY180552A (en) 2011-04-01 2020-12-02 Mannkind Corp Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
WO2012175735A1 (en) 2011-06-23 2012-12-27 Vib Vzw A20 inhibitors for the treatment of respiratory viral infections
PT2723176T (pt) 2011-06-27 2017-07-18 Parion Sciences Inc Dipéptido química e metabolicamente estável que possui potente atividade bloqueadora do canal de sódio
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
EP2822474B1 (en) 2012-03-06 2018-05-02 Ferrosan Medical Devices A/S Pressurized container containing haemostatic paste
NZ629898A (en) 2012-03-23 2016-04-29 Oxigene Inc Compositions and methods for inhibition of cathepsins
BR112014030962A2 (pt) 2012-06-12 2017-06-27 Ferrosan Medical Devices As métodos para preparação e para reconstituição de uma composição seca adequada para uso em hemostase e cicatrização de feridas, e, kit hemostático
CA2878457C (en) 2012-07-12 2021-01-19 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
TW201427681A (zh) 2013-01-07 2014-07-16 Superlab Far East Ltd 用空間構象改變的重組干擾素治療腫瘤的方法
BR112015023168B1 (pt) 2013-03-15 2021-08-10 Mannkind Corporation Composição de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina cristalina, método de produção de partículas de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina e uso de uma composição de dicetopiperazina cristalina
EP2968545B1 (en) 2013-03-15 2019-03-06 Memorial Sloan Kettering Cancer Center High affinity anti-gd2 antibodies
US9724078B2 (en) 2013-06-21 2017-08-08 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
CN114848614A (zh) 2013-07-18 2022-08-05 曼金德公司 热稳定性干粉药物组合物和方法
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
EP3470094B1 (en) 2013-12-11 2020-07-22 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
WO2016044839A2 (en) 2014-09-19 2016-03-24 The Board Of Regents Of The University Of Texas System Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
WO2016058612A1 (en) 2014-10-13 2016-04-21 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
WO2016102446A1 (en) 2014-12-24 2016-06-30 Ferrosan Medical Devices A/S Syringe for retaining and mixing first and second substances
AU2016233309B2 (en) 2015-03-17 2021-11-18 Memorial Sloan Kettering Cancer Center Anti-MUC16 antibodies and uses thereof
WO2017005590A1 (en) 2015-07-03 2017-01-12 Ferrosan Medical Devices A/S Syringe for mixing two components and for retaining a vacuum in a storage condition
JP2019524721A (ja) 2016-07-15 2019-09-05 ポセイダ セラピューティクス， インコーポレイテッド キメラ抗原受容体および使用方法
MX2019000641A (es) 2016-07-15 2019-06-10 Poseida Therapeutics Inc Composiciones de mucina1-receptor de antigeno quimerico y metodos para su uso.
BR112019009469A2 (pt) 2016-11-09 2019-07-30 Pulmotect Inc métodos e composições para a modulação imunológica adaptativa
WO2018112037A1 (en) 2016-12-16 2018-06-21 Jia Zhou Inhibitors of bromodomain-containing protein 4 (brd4)
EP3574012A1 (en) 2017-01-27 2019-12-04 Memorial Sloan Kettering Cancer Center Bispecific her2 and cd3 binding molecules
CN110234351A (zh) 2017-01-30 2019-09-13 詹森生物科技公司 用于治疗活动性银屑病关节炎的抗tnf抗体、组合物和方法
CN110418652A (zh) 2017-02-07 2019-11-05 詹森生物科技公司 用于治疗活动性强直性脊柱炎的抗tnf抗体、组合物和方法
KR20200116917A (ko) 2017-12-20 2020-10-13 포세이다 테라퓨틱스, 인크. Vcar 조성물 및 사용 방법
KR102016848B1 (ko) * 2018-03-06 2019-08-30 주식회사 케이티앤지 흡연 물품용 카트리지 및 이의 에어로졸 흡입기
KR102019593B1 (ko) * 2018-03-06 2019-09-06 주식회사 케이티앤지 에어로졸 흡입기
KR102019595B1 (ko) * 2018-03-07 2019-09-06 주식회사 케이티앤지 담배 물질 흡입기
US20210154418A1 (en) * 2018-05-08 2021-05-27 Societe Industrielle De Sonceboz Sa Inhaler
EP4321182A2 (en) 2018-05-09 2024-02-14 Ferrosan Medical Devices A/S Method for preparing a haemostatic composition
MA52590A (fr) 2018-05-11 2021-03-17 Janssen Biotech Inc Méthodes de traitement de la dépression à l'aide d'anticorps il-23
US11389433B2 (en) 2018-06-18 2022-07-19 Board Of Regents, The University Of Texas System BRD4 inhibitor treatment of IgE-mediated diseases
WO2020092845A1 (en) 2018-11-01 2020-05-07 Rigel Pharmaceuticals, Inc. Method and composition embodiments for treating acute myeloid leukemia
EP3893973A4 (en) 2018-12-13 2022-09-07 ResMed Pty Ltd PNEUMATIC BLOCK FOR RESPIRATORY PRESSURE THERAPY DEVICE
JP2022518208A (ja) 2019-01-15 2022-03-14 ヤンセン バイオテツク，インコーポレーテツド 若年性特発性関節炎の治療のための抗ｔｎｆ抗体、組成物、及び方法
WO2020152544A1 (en) 2019-01-23 2020-07-30 Janssen Biotech, Inc. Anti-tnf antibody compositions for use in methods for the treatment of psoriatic arthritis
KR20210142002A (ko) 2019-03-14 2021-11-23 얀센 바이오테크 인코포레이티드 항-tnf 항체 조성물을 생성하기 위한 제조 방법
CA3133388A1 (en) 2019-03-14 2020-09-17 Janssen Biotech, Inc. Methods for producing anti-tnf antibody compositions
MA55283A (fr) 2019-03-14 2022-01-19 Janssen Biotech Inc Procédés de production de compositions d'anticorps anti-tnf
US11780911B2 (en) 2019-05-23 2023-10-10 Janssen Biotech, Inc. Method of treating inflammatory bowel disease with a combination therapy of antibodies to IL-23 and TNF alpha
WO2020243612A1 (en) 2019-05-29 2020-12-03 Rigel Pharmaceuticals, Inc. Method of preventing and treating thrombosis
CN113939531A (zh) 2019-06-03 2022-01-14 詹森生物科技公司 用于治疗银屑病关节炎的抗tnf抗体组合物和方法
MX2021014882A (es) 2019-06-03 2022-03-25 Janssen Biotech Inc Anticuerpos anti-tnf, composiciones y métodos para el tratamiento de la espondilitis anquilosante activa.
CN114698370A (zh) 2019-08-08 2022-07-01 里格尔药品股份有限公司 用于治疗细胞因子释放综合征的化合物和方法
EP4013420B1 (en) 2019-08-14 2023-11-01 Rigel Pharmaceuticals, Inc. Method of blocking or ameliorating cytokine release syndrome
WO2021028752A1 (en) 2019-08-15 2021-02-18 Janssen Biotech, Inc. Anti-tfn antibodies for treating type i diabetes
US20230190811A1 (en) 2020-04-14 2023-06-22 Poseida Therapeutics, Inc. Compositions and methods for use in the treatment of cancer
WO2021214587A1 (en) 2020-04-21 2021-10-28 Janssen Biotech, Inc. Anti-tnf alpha agent for treating viral infections
WO2021214588A1 (en) 2020-04-21 2021-10-28 Janssen Biotech, Inc. Anti-tnf alpha agent for treating coronavirus infections
CN116782920A (zh) 2020-07-31 2023-09-19 常青树治疗公司 用于治疗病毒感染的神经毡蛋白和血管紧张素转化酶2融合肽
WO2023279115A1 (en) 2021-07-02 2023-01-05 Henry Ford Health System Compositions comprising endosidin 2 for reducing sars-cov-2 infection
CN117957251A (zh) 2021-07-09 2024-04-30 詹森生物科技公司 用于制备抗tnf抗体组合物的制造方法
WO2023281462A1 (en) 2021-07-09 2023-01-12 Janssen Biotech, Inc. Manufacturing methods for producing anti-tnf antibody compositions
US20230303555A1 (en) 2022-03-23 2023-09-28 Rigel Pharmaceuticals, Inc. Pyrimid-2-yl-pyrazole compounds as irak inhibitors

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1262085A (en) * 1965-03-19 1972-02-02 Fisons Pharmaceuticals Ltd Inhalation device
GB1142015A (en) * 1965-09-10 1969-02-05 Unilever Ltd Preservation of foodstuffs
US3669113A (en) * 1966-03-07 1972-06-13 Fisons Ltd Inhalation device
US3507277A (en) * 1966-09-17 1970-04-21 Fisons Pharmaceuticals Ltd Inhalation device
GB1182779A (en) * 1966-09-17 1970-03-04 Fisons Pharmaceuticals Ltd Inhalation Device
GB1268051A (en) * 1968-06-07 1972-03-22 Fisons Pharmaceuticals Ltd Inhalation device
US3831606A (en) * 1971-02-19 1974-08-27 Alza Corp Auto inhaler
US3812853A (en) * 1971-11-17 1974-05-28 P Crain Apparatus for applying medication or the like to human nasal passages
US3971377A (en) * 1974-06-10 1976-07-27 Alza Corporation Medicament dispensing process for inhalation therapy
US4147166A (en) * 1977-05-02 1979-04-03 American Cyanamid Company Oral inhalator powder dispenser
US4452239A (en) * 1980-03-25 1984-06-05 Hilal Malem Medical nebulizing apparatus
US4307734A (en) * 1980-06-23 1981-12-29 B & B Inventors & Marketers, Inc. Snuff dispenser
DE3274065D1 (de) * 1981-07-08 1986-12-11 Draco Ab Powder inhalator
US4509515A (en) * 1982-02-23 1985-04-09 Fisons Plc Inhalation device
CA1224992A (en) * 1982-10-08 1987-08-04 Robert E. Newell Device for administering medicament to patients
US4534343A (en) * 1984-01-27 1985-08-13 Trutek Research, Inc. Metered dose inhaler
SE448277B (sv) * 1985-04-12 1987-02-09 Draco Ab Indikeringsanordning vid en doseringsanordning for lekemedel
AT384552B (de) * 1985-08-01 1987-12-10 Hurka Wilhelm Inhalationsgeraet zur dosierung und verteilung von festkoerpern in die atemluft
US4739754A (en) * 1986-05-06 1988-04-26 Shaner William T Suction resistant inhalator
WO1990013327A1 (en) * 1989-04-28 1990-11-15 Riker Laboratories, Inc. Dry powder inhalation device
US5176132A (en) * 1989-05-31 1993-01-05 Fisons Plc Medicament inhalation device and formulation
IT1237118B (it) * 1989-10-27 1993-05-18 Miat Spa Inalatore multidose per farmaci in polvere.
US5113855A (en) * 1990-02-14 1992-05-19 Newhouse Michael T Powder inhaler
GB9021433D0 (en) * 1990-10-02 1990-11-14 Atomic Energy Authority Uk Power inhaler
US5327883A (en) * 1991-05-20 1994-07-12 Dura Pharmaceuticals, Inc. Apparatus for aerosolizing powdered medicine and process and using
US5161524A (en) * 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means

Similar Documents

Publication Publication Date Title
RU95114532A (ru) Устройство для распыления лекарственного средства в форме порошка
UA27938C2 (ru) Устройство для распыления лекарственного средства в форме порошка для ингаляций
IL108780A0 (en) An inhalation device
MY133634A (en) Filter and valve apparatus
CA2225750A1 (en) Inhalation device and method
TW350795B (en) Powder atomizer
CA2322434A1 (en) Medicament delivery and packaging
CA2097288A1 (en) Inhalation device
CA2020137A1 (en) Medicament Inhalation Device
CA2084214A1 (en) An inhaler
JPS5699893A (en) Air intake duct for outboard-engine
CA2152158A1 (en) Gas expelling device
JPS53136136A (en) Fuel discharge equipment of internal combustion engine
RU92004346A (ru) Сухой скруббер с низким падением давления
UA27129C2 (ru) Способ и устройство для многократного дозирования жидкого препарата фармацевтически активного средства
CA2446543A1 (en) Apparatus for use in slurry pumps
ES2116973T3 (es) Dispositivo para la entrega dosificada de liquido.
JPS52106107A (en) Vortex flow blower
JPS5749100A (en) Double suction type fan
JPS5660893A (en) Self-priming pump
RU94042013A (ru) Ингалятор
RU92011833A (ru) Автоматический огнетушитель
JPH03115043U (ru)
JPS55167082A (en) Evaporation treatment apparatus
ES1038727U (es) Dispensador de pastillas perfeccionado.