RU2456266C1 - Производные 4,4'-бифениламидов, обладающие фармакологической активностью, и лекарственные средства на их основе - Google Patents
Производные 4,4'-бифениламидов, обладающие фармакологической активностью, и лекарственные средства на их основе Download PDFInfo
- Publication number
- RU2456266C1 RU2456266C1 RU2011113045/15A RU2011113045A RU2456266C1 RU 2456266 C1 RU2456266 C1 RU 2456266C1 RU 2011113045/15 A RU2011113045/15 A RU 2011113045/15A RU 2011113045 A RU2011113045 A RU 2011113045A RU 2456266 C1 RU2456266 C1 RU 2456266C1
- Authority
- RU
- Russia
- Prior art keywords
- compound according
- diylbis
- diyl
- biphenyl
- carboxamide
- Prior art date
Links
- 0 CC(*)(C=CN=C1)C=C1C(C)=O Chemical compound CC(*)(C=CN=C1)C=C1C(C)=O 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/27—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2011113045/15A RU2456266C1 (ru) | 2011-04-06 | 2011-04-06 | Производные 4,4'-бифениламидов, обладающие фармакологической активностью, и лекарственные средства на их основе |
PCT/RU2012/000238 WO2012138254A2 (fr) | 2011-04-06 | 2012-04-02 | Dérivés de 4,4'-diphénylamines possédant une activité pharmacologique et médicaments sur leur base |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2011113045/15A RU2456266C1 (ru) | 2011-04-06 | 2011-04-06 | Производные 4,4'-бифениламидов, обладающие фармакологической активностью, и лекарственные средства на их основе |
Publications (1)
Publication Number | Publication Date |
---|---|
RU2456266C1 true RU2456266C1 (ru) | 2012-07-20 |
Family
ID=46847377
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2011113045/15A RU2456266C1 (ru) | 2011-04-06 | 2011-04-06 | Производные 4,4'-бифениламидов, обладающие фармакологической активностью, и лекарственные средства на их основе |
Country Status (2)
Country | Link |
---|---|
RU (1) | RU2456266C1 (fr) |
WO (1) | WO2012138254A2 (fr) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2297243C2 (ru) * | 2001-09-27 | 2007-04-20 | Алькон, Инк. | Ингибиторы киназы-3 гликогенсинтазы (gsk-3) для лечения глаукомы |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200628153A (en) * | 2004-10-05 | 2006-08-16 | Smithkline Beecham Corp | Novel compounds |
EP1940786B1 (fr) * | 2005-09-16 | 2010-08-18 | Arrow Therapeutics Limited | Dérivés de biphényle et leur utilisation dans le traitement de l'hépatite c |
CN105130957A (zh) * | 2009-05-29 | 2015-12-09 | 拉夸里亚创药株式会社 | 作为钙或钠通道阻滞剂的芳基取代羧酰胺衍生物 |
RU2417082C2 (ru) * | 2009-07-14 | 2011-04-27 | Учреждение Российской Академии Наук Институт Физиологически Активных Веществ Ран (Ифав Ран) | Средство для восстановления утраченной памяти в норме и патологии у пациентов всех возрастных групп на основе n, n'-замещенных 3, 7-диазабицикло[3.3.1]нонанов, фармацевтическая композиция на его основе и способ ее применения |
-
2011
- 2011-04-06 RU RU2011113045/15A patent/RU2456266C1/ru active
-
2012
- 2012-04-02 WO PCT/RU2012/000238 patent/WO2012138254A2/fr active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2297243C2 (ru) * | 2001-09-27 | 2007-04-20 | Алькон, Инк. | Ингибиторы киназы-3 гликогенсинтазы (gsk-3) для лечения глаукомы |
Non-Patent Citations (1)
Title |
---|
Luquin MR, Obeso JA, Laguna J, Guillén J, Martínez-Lage JM., The AMPA receptor antagonist NBQX does not alter the motor response induced by selective dopamine agonists in MPTP-treated monkeys., Eur J Pharmacol. 1993, N.235, V.2-3, p.p.297-300. * |
Also Published As
Publication number | Publication date |
---|---|
WO2012138254A3 (fr) | 2012-12-13 |
WO2012138254A2 (fr) | 2012-10-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
RU2333211C1 (ru) | N,n`-замещенные 3, 7-диазабицикло[3.3.1]нонаны, обладающие фармакологической активностью, фармацевтические композиции на их основе и способ их применения | |
US8173644B2 (en) | 3-substituted-[1,2,3]-benzotriazinone compound for enhancing glutamatergic synaptic responses | |
JP5913651B2 (ja) | 疼痛および他の疾患の処置のための化合物および方法 | |
JP6402115B2 (ja) | 神経学的疾患および状態の処置に有用なスピロ−キナゾリノン誘導体 | |
CZ299765B6 (cs) | Benzofurazanová sloucenina, její použití a farmaceutická kompozice ji obsahující | |
CA2828831C (fr) | Composes et methodes de traitement de la douleur et d'autres troubles | |
RU2456266C1 (ru) | Производные 4,4'-бифениламидов, обладающие фармакологической активностью, и лекарственные средства на их основе | |
RU2480470C2 (ru) | Трициклические производные n,n'-замещенных 3,7-диазабицикло[3.3.1]нонанов, обладающие фармакологической активностью, и лекарственные средства на их основе | |
US9067940B2 (en) | Alicyclic derivatives of N,N'-substituted 3,7-diazabicyclo[3.3.1]nonanes and medicaments based thereon | |
RU2810080C1 (ru) | Трициклические производные биспидина, способ их получения и применения | |
KR101197754B1 (ko) | 글루타메이트성 시냅스 반응을 향상시키기 위한 3치환된〔1,2,3〕벤조트리아지논 화합물 | |
JP6751161B2 (ja) | フッ素含有トリアゾロピリジン系化合物、その製造方法、医薬組成物及び用途 | |
JP2015166385A (ja) | 疼痛および他の障害の処置のための化合物および方法 | |
Gao | The development and evaluation of multi-target-directed ligands as cholinergic and amyloid β aggregation inhibitors for Alzheimer's disease | |
JP2012516845A (ja) | グルタミン酸作動性シナプス反応を増強するための二環式アミド誘導体 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC41 | Official registration of the transfer of exclusive right |
Effective date: 20181212 |
|
HE4A | Change of address of a patent owner |
Effective date: 20200313 |