RU2456266C1 - Производные 4,4'-бифениламидов, обладающие фармакологической активностью, и лекарственные средства на их основе - Google Patents

Производные 4,4'-бифениламидов, обладающие фармакологической активностью, и лекарственные средства на их основе Download PDF

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Publication number
RU2456266C1
RU2456266C1 RU2011113045/15A RU2011113045A RU2456266C1 RU 2456266 C1 RU2456266 C1 RU 2456266C1 RU 2011113045/15 A RU2011113045/15 A RU 2011113045/15A RU 2011113045 A RU2011113045 A RU 2011113045A RU 2456266 C1 RU2456266 C1 RU 2456266C1
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RU
Russia
Prior art keywords
compound according
diylbis
diyl
biphenyl
carboxamide
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RU2011113045/15A
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English (en)
Russian (ru)
Inventor
Николай Серафимович Зефиров (RU)
Николай Серафимович Зефиров
Владимир Александрович Палюлин (RU)
Владимир Александрович Палюлин
Мстислав Игоревич Лавров (RU)
Мстислав Игоревич Лавров
Алексей Сергеевич Морозов (RU)
Алексей Сергеевич Морозов
Вера Леонидовна Лаптева (RU)
Вера Леонидовна Лаптева
Максим Эдуардович Запольский (RU)
Максим Эдуардович Запольский
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Максим Эдуардович Запольский
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Priority to RU2011113045/15A priority Critical patent/RU2456266C1/ru
Priority to PCT/RU2012/000238 priority patent/WO2012138254A2/fr
Application granted granted Critical
Publication of RU2456266C1 publication Critical patent/RU2456266C1/ru

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/27Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RU2011113045/15A 2011-04-06 2011-04-06 Производные 4,4'-бифениламидов, обладающие фармакологической активностью, и лекарственные средства на их основе RU2456266C1 (ru)

Priority Applications (2)

Application Number Priority Date Filing Date Title
RU2011113045/15A RU2456266C1 (ru) 2011-04-06 2011-04-06 Производные 4,4'-бифениламидов, обладающие фармакологической активностью, и лекарственные средства на их основе
PCT/RU2012/000238 WO2012138254A2 (fr) 2011-04-06 2012-04-02 Dérivés de 4,4'-diphénylamines possédant une activité pharmacologique et médicaments sur leur base

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2011113045/15A RU2456266C1 (ru) 2011-04-06 2011-04-06 Производные 4,4'-бифениламидов, обладающие фармакологической активностью, и лекарственные средства на их основе

Publications (1)

Publication Number Publication Date
RU2456266C1 true RU2456266C1 (ru) 2012-07-20

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RU2011113045/15A RU2456266C1 (ru) 2011-04-06 2011-04-06 Производные 4,4'-бифениламидов, обладающие фармакологической активностью, и лекарственные средства на их основе

Country Status (2)

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RU (1) RU2456266C1 (fr)
WO (1) WO2012138254A2 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2297243C2 (ru) * 2001-09-27 2007-04-20 Алькон, Инк. Ингибиторы киназы-3 гликогенсинтазы (gsk-3) для лечения глаукомы

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200628153A (en) * 2004-10-05 2006-08-16 Smithkline Beecham Corp Novel compounds
EP1940786B1 (fr) * 2005-09-16 2010-08-18 Arrow Therapeutics Limited Dérivés de biphényle et leur utilisation dans le traitement de l'hépatite c
CN105130957A (zh) * 2009-05-29 2015-12-09 拉夸里亚创药株式会社 作为钙或钠通道阻滞剂的芳基取代羧酰胺衍生物
RU2417082C2 (ru) * 2009-07-14 2011-04-27 Учреждение Российской Академии Наук Институт Физиологически Активных Веществ Ран (Ифав Ран) Средство для восстановления утраченной памяти в норме и патологии у пациентов всех возрастных групп на основе n, n'-замещенных 3, 7-диазабицикло[3.3.1]нонанов, фармацевтическая композиция на его основе и способ ее применения

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2297243C2 (ru) * 2001-09-27 2007-04-20 Алькон, Инк. Ингибиторы киназы-3 гликогенсинтазы (gsk-3) для лечения глаукомы

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Luquin MR, Obeso JA, Laguna J, Guillén J, Martínez-Lage JM., The AMPA receptor antagonist NBQX does not alter the motor response induced by selective dopamine agonists in MPTP-treated monkeys., Eur J Pharmacol. 1993, N.235, V.2-3, p.p.297-300. *

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Publication number Publication date
WO2012138254A3 (fr) 2012-12-13
WO2012138254A2 (fr) 2012-10-11

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