RU2014143979A - Пригодные для использования в пищу бактерии lactobacillus rhamnosus - Google Patents
Пригодные для использования в пищу бактерии lactobacillus rhamnosus Download PDFInfo
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- RU2014143979A RU2014143979A RU2014143979A RU2014143979A RU2014143979A RU 2014143979 A RU2014143979 A RU 2014143979A RU 2014143979 A RU2014143979 A RU 2014143979A RU 2014143979 A RU2014143979 A RU 2014143979A RU 2014143979 A RU2014143979 A RU 2014143979A
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- strain
- lactobacillus rhamnosus
- cell fraction
- composition
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- 241000218588 Lactobacillus rhamnosus Species 0.000 title claims abstract 13
- 238000000034 method Methods 0.000 claims abstract 7
- 239000000203 mixture Substances 0.000 claims abstract 6
- 230000002068 genetic effect Effects 0.000 claims abstract 2
- 239000001963 growth medium Substances 0.000 claims abstract 2
- 239000008267 milk Substances 0.000 claims abstract 2
- 210000004080 milk Anatomy 0.000 claims abstract 2
- 235000013336 milk Nutrition 0.000 claims abstract 2
- 238000002703 mutagenesis Methods 0.000 claims abstract 2
- 231100000350 mutagenesis Toxicity 0.000 claims abstract 2
- LWGJTAZLEJHCPA-UHFFFAOYSA-N n-(2-chloroethyl)-n-nitrosomorpholine-4-carboxamide Chemical compound ClCCN(N=O)C(=O)N1CCOCC1 LWGJTAZLEJHCPA-UHFFFAOYSA-N 0.000 claims abstract 2
- 230000009466 transformation Effects 0.000 claims abstract 2
- 238000012258 culturing Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
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- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
- A23C9/123—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
- A23C9/1234—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt characterised by using a Lactobacillus sp. other than Lactobacillus Bulgaricus, including Bificlobacterium sp.
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
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- A—HUMAN NECESSITIES
- A62—LIFE-SAVING; FIRE-FIGHTING
- A62D—CHEMICAL MEANS FOR EXTINGUISHING FIRES OR FOR COMBATING OR PROTECTING AGAINST HARMFUL CHEMICAL AGENTS; CHEMICAL MATERIALS FOR USE IN BREATHING APPARATUS
- A62D3/00—Processes for making harmful chemical substances harmless or less harmful, by effecting a chemical change in the substances
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- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
- A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/175—Rhamnosus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/225—Lactobacillus
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
1. Штамм пригодных для использования в пищу бактерий Lactobacillus rhamnosus, который представляет собой штамм, депонированный в CNCM под номером I-4719.2. Способ получения штамма Lactobacillus rhamnosus, который включает стадию мутагенеза или генетической трансформации штамма Lactobacillus rhamnosus по п. 1.3. Модифицированный штамм Lactobacillus rhamnosus, полученный способом по п. 2.4. Способ получения фракции клеток, включающий следующие стадии:a) культивирование штамма Lactobacillus rhamnosus по п. 1 или 3, иb) выделение фракции клеток из культуральной среды на стадии a).5. Фракция клеток, полученная способом по п. 4.6. Композиция, содержащая штамм Lactobacillus rhamnosus по п. 1 или 3 или фракцию клеток по п. 5.7. Композиция по п. 6, дополнительно содержащая носитель.8. Композиция по п. 6, содержащая носитель, который представляет собой продукт на основе молока.
Claims (8)
1. Штамм пригодных для использования в пищу бактерий Lactobacillus rhamnosus, который представляет собой штамм, депонированный в CNCM под номером I-4719.
2. Способ получения штамма Lactobacillus rhamnosus, который включает стадию мутагенеза или генетической трансформации штамма Lactobacillus rhamnosus по п. 1.
3. Модифицированный штамм Lactobacillus rhamnosus, полученный способом по п. 2.
4. Способ получения фракции клеток, включающий следующие стадии:
a) культивирование штамма Lactobacillus rhamnosus по п. 1 или 3, и
b) выделение фракции клеток из культуральной среды на стадии a).
5. Фракция клеток, полученная способом по п. 4.
6. Композиция, содержащая штамм Lactobacillus rhamnosus по п. 1 или 3 или фракцию клеток по п. 5.
7. Композиция по п. 6, дополнительно содержащая носитель.
8. Композиция по п. 6, содержащая носитель, который представляет собой продукт на основе молока.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261620796P | 2012-04-05 | 2012-04-05 | |
| US61/620,796 | 2012-04-05 | ||
| PCT/IB2013/052739 WO2013150497A1 (en) | 2012-04-05 | 2013-04-05 | Lactobacillus rhamnosus food grade bacteria |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2014143979A true RU2014143979A (ru) | 2016-05-27 |
| RU2639547C2 RU2639547C2 (ru) | 2017-12-21 |
Family
ID=48471060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2014143979A RU2639547C2 (ru) | 2012-04-05 | 2013-04-05 | Пригодные для использования в пищу бактерии lactobacillus rhamnosus |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US9540609B2 (ru) |
| EP (2) | EP2833898B1 (ru) |
| CN (2) | CN104540934A (ru) |
| CA (1) | CA2869566C (ru) |
| RU (1) | RU2639547C2 (ru) |
| WO (2) | WO2013150497A1 (ru) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9540609B2 (en) * | 2012-04-05 | 2017-01-10 | Compagnie Gervais Danone | Lactobacillus rhamnosus food grade bacteria |
| US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
| ES2659064T3 (es) * | 2014-12-12 | 2018-03-13 | Compagnie Gervais Danone | Bacterias de Lactobacillus Rhamnosus de calidad alimentaria |
| CN104489489B (zh) * | 2015-01-12 | 2017-05-03 | 湖南农业大学 | 一种利用乳杆菌和酵母菌混合发酵消减大米中重金属镉的方法 |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| CN106616042A (zh) * | 2016-12-23 | 2017-05-10 | 江南大学 | 一种植物乳杆菌饲料及其应用 |
| PL233582B1 (pl) * | 2017-08-21 | 2019-11-29 | Politechnika Lodzka | Szczep bakterii mlekowych Lactobacillus rhamnosus |
| CN109207405B (zh) * | 2018-10-22 | 2021-04-27 | 江苏省家禽科学研究所 | 一种耐镉乳酸菌及其应用 |
| CN109260645B (zh) * | 2018-10-31 | 2021-07-02 | 湖南中茂生物科技有限公司 | 一种去除植物来源黄酮类提取物中残留农药的方法 |
| CN109527339A (zh) * | 2018-11-30 | 2019-03-29 | 东北农业大学 | 一种利用鼠李糖乳杆菌去除液体样品中展青霉素的方法 |
| CN110317758A (zh) * | 2019-07-19 | 2019-10-11 | 河南广安生物科技股份有限公司 | 一种肉鸡双毒素解毒剂及其制备方法 |
| CN110591988B (zh) * | 2019-11-01 | 2021-05-14 | 四川农业大学 | 鼠李糖乳杆菌753及其应用、青贮饲料添加剂、青贮饲料 |
| CN112708583B (zh) * | 2021-01-29 | 2022-05-17 | 重庆第二师范学院 | 一种发酵乳杆菌lf-schy34及其应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5531988A (en) | 1994-10-28 | 1996-07-02 | Metagenics, Inc. | Bacteria and immunoglobulin-containing composition for human gastrointestinal health |
| US6080401A (en) | 1998-11-19 | 2000-06-27 | Reddy; Malireddy S. | Herbal and pharmaceutical drugs enhanced with probiotics |
| EP1137423B1 (en) | 1998-12-11 | 2005-03-09 | Urex Biotech, Inc. | Oral administration of lactobacillus for the treatment and prevention of urogenital infection |
| US6641808B1 (en) | 1999-09-22 | 2003-11-04 | Lacpro Industries, Llc | Composition for treatment of obesity |
| TW588109B (en) * | 2000-07-29 | 2004-05-21 | Tcell Biotechnology Food Co Lt | Lactobacillus rhamnosus strain and uses thereof |
| US20090035288A1 (en) * | 2005-07-20 | 2009-02-05 | Ruud Albers | Edible product containing beneficial bacteria |
| RU2332993C2 (ru) * | 2006-10-19 | 2008-09-10 | ООО "Научно-технический центр "Промбезопасность-Оренбург" | Способ защиты организма человека от неблагоприятных воздействий окружающей среды и композиция для его осуществления |
| CN100522852C (zh) * | 2007-06-20 | 2009-08-05 | 上海裕麒环境技术服务有限公司 | 一种污水处理过程中污泥循环再利用方法 |
| CN101333502A (zh) * | 2007-06-27 | 2008-12-31 | 上海泓宝绿色水产科技发展有限公司 | 应急菌的制备和修复水产养殖环境的方法 |
| US20090029447A1 (en) * | 2007-07-26 | 2009-01-29 | West Virginia University | Process for removing mercury from air or water |
| FR2928935B1 (fr) * | 2008-03-19 | 2011-05-20 | Gervais Danone Sa | Souche de lactobacillus rhamnosus. |
| EP2579881A4 (en) * | 2010-05-25 | 2015-01-21 | David Kossor | COMPOSITIONS AND METHODS FOR REDUCING THE TOXICITY OF MERCURY |
| US9540609B2 (en) * | 2012-04-05 | 2017-01-10 | Compagnie Gervais Danone | Lactobacillus rhamnosus food grade bacteria |
| CN102872475B (zh) * | 2012-09-26 | 2015-04-15 | 天津市伯曼生物科技有限公司 | 一种除臭降铬的生物制剂及其制备方法 |
-
2013
- 2013-04-05 US US14/390,018 patent/US9540609B2/en active Active
- 2013-04-05 EP EP13771919.1A patent/EP2833898B1/en active Active
- 2013-04-05 CN CN201380029689.4A patent/CN104540934A/zh active Pending
- 2013-04-05 RU RU2014143979A patent/RU2639547C2/ru active
- 2013-04-05 WO PCT/IB2013/052739 patent/WO2013150497A1/en active Application Filing
- 2013-04-05 US US14/390,685 patent/US10487305B2/en active Active
- 2013-04-05 WO PCT/CA2013/000328 patent/WO2013149333A1/en active Application Filing
- 2013-04-05 CN CN201380029656.XA patent/CN104755090B/zh not_active Expired - Fee Related
- 2013-04-05 CA CA2869566A patent/CA2869566C/en active Active
- 2013-04-05 EP EP13724404.2A patent/EP2834377A1/en not_active Ceased
-
2019
- 2019-11-06 US US16/676,021 patent/US20200140806A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013149333A1 (en) | 2013-10-10 |
| WO2013150497A1 (en) | 2013-10-10 |
| US9540609B2 (en) | 2017-01-10 |
| EP2833898A1 (en) | 2015-02-11 |
| EP2833898A4 (en) | 2015-12-09 |
| US10487305B2 (en) | 2019-11-26 |
| CN104755090A (zh) | 2015-07-01 |
| CN104755090B (zh) | 2020-10-20 |
| US20200140806A1 (en) | 2020-05-07 |
| CA2869566C (en) | 2022-08-30 |
| EP2834377A1 (en) | 2015-02-11 |
| RU2639547C2 (ru) | 2017-12-21 |
| CN104540934A (zh) | 2015-04-22 |
| US20150079236A1 (en) | 2015-03-19 |
| EP2833898B1 (en) | 2018-11-14 |
| US20150191691A1 (en) | 2015-07-09 |
| CA2869566A1 (en) | 2013-10-10 |
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