RU2014124530A - Антитела к cd98 и способы их применения - Google Patents
Антитела к cd98 и способы их применения Download PDFInfo
- Publication number
- RU2014124530A RU2014124530A RU2014124530/10A RU2014124530A RU2014124530A RU 2014124530 A RU2014124530 A RU 2014124530A RU 2014124530/10 A RU2014124530/10 A RU 2014124530/10A RU 2014124530 A RU2014124530 A RU 2014124530A RU 2014124530 A RU2014124530 A RU 2014124530A
- Authority
- RU
- Russia
- Prior art keywords
- antibody
- functional fragment
- seq
- human
- variable region
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/515—Complete light chain, i.e. VL + CL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161563443P | 2011-11-23 | 2011-11-23 | |
| US61/563,443 | 2011-11-23 | ||
| PCT/US2012/066347 WO2013078377A1 (en) | 2011-11-23 | 2012-11-21 | Anti-cd98 antibodies and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2014124530A true RU2014124530A (ru) | 2015-12-27 |
Family
ID=47295209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2014124530/10A RU2014124530A (ru) | 2011-11-23 | 2012-11-21 | Антитела к cd98 и способы их применения |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP2782935A1 (pt) |
| JP (1) | JP2015501639A (pt) |
| KR (1) | KR20140125351A (pt) |
| CN (1) | CN104302669A (pt) |
| AU (1) | AU2012340623A1 (pt) |
| BR (1) | BR112014012590A8 (pt) |
| CA (1) | CA2856873A1 (pt) |
| HK (1) | HK1202877A1 (pt) |
| IL (1) | IL232755A0 (pt) |
| MX (1) | MX2014006272A (pt) |
| PH (1) | PH12014501164A1 (pt) |
| RU (1) | RU2014124530A (pt) |
| SG (1) | SG11201402619VA (pt) |
| WO (1) | WO2013078377A1 (pt) |
| ZA (1) | ZA201403760B (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2865068T3 (es) | 2011-01-14 | 2021-10-14 | Univ California | Anticuerpos terapéuticos contra la proteína ROR-1 y métodos para usarlos |
| WO2014197871A2 (en) * | 2013-06-06 | 2014-12-11 | Igenica Biotherapeutics, Inc. | Antibody-drug conjugates, compositions and methods of use |
| WO2014197866A1 (en) | 2013-06-06 | 2014-12-11 | Igenica Biotherapeutics, Inc. | Modified antibodies and related compounds, compositions, and methods of use |
| JP2017114763A (ja) * | 2014-03-26 | 2017-06-29 | 第一三共株式会社 | 抗ｃｄ９８抗体−薬物コンジュゲート |
| RU2017120039A (ru) * | 2014-12-10 | 2019-01-10 | Дженентек, Инк. | Антитела к рецепторам гематоэнцефалического барьера и способы их применения |
| ES2905534T3 (es) * | 2015-08-10 | 2022-04-11 | Univ Osaka | Anticuerpo |
| CN105385694B (zh) * | 2015-11-20 | 2019-01-18 | 中国人民解放军第四军医大学 | 抗人cd98单克隆抗体98-3h3轻、重链可变区基因及其应用 |
| CN116284404A (zh) | 2016-06-08 | 2023-06-23 | 艾伯维公司 | 抗b7-h3抗体和抗体药物偶联物 |
| AU2017277916A1 (en) * | 2016-06-08 | 2019-01-03 | Abbvie Inc. | Anti-CD98 antibodies and antibody drug conjugates |
| US20200121803A1 (en) * | 2016-06-08 | 2020-04-23 | Abbvie Inc. | Anti-cd98 antibodies and antibody drug conjugates |
| CN109562169A (zh) * | 2016-06-08 | 2019-04-02 | 艾伯维公司 | 抗cd98抗体及抗体药物偶联物 |
| CA3090519A1 (en) | 2018-02-07 | 2019-08-15 | Regeneron Pharmaceuticals, Inc. | Methods and compositions for therapeutic protein delivery |
| EP3715370A1 (en) * | 2019-03-28 | 2020-09-30 | Technische Universität München | High affinity anticalins directed against human cd98hc |
| WO2021205361A1 (en) * | 2020-04-08 | 2021-10-14 | Janssen Biotech, Inc. | Anti-cd98 antibodies and uses thereof |
| AR124681A1 (es) | 2021-01-20 | 2023-04-26 | Abbvie Inc | Conjugados anticuerpo-fármaco anti-egfr |
| WO2022252167A1 (en) * | 2021-06-02 | 2022-12-08 | Huahui Health Ltd. | Anti-cd98 antibodies and uses thereof |
| CN115772541A (zh) * | 2021-12-17 | 2023-03-10 | 百奥赛图江苏基因生物技术有限公司 | Cd98hc基因人源化非人动物的构建方法及应用 |
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| TWI390034B (zh) | 2006-04-06 | 2013-03-21 | Kyowa Hakko Kirin Co Ltd | Novel anti-CD98 antibody |
| GB0615662D0 (en) * | 2006-08-07 | 2006-09-13 | Affitech As | Antibody |
| JPWO2011118804A1 (ja) * | 2010-03-26 | 2013-07-04 | 国立大学法人徳島大学 | 新規抗ｃｄ９８抗体とその用途 |
-
2012
- 2012-11-21 MX MX2014006272A patent/MX2014006272A/es unknown
- 2012-11-21 WO PCT/US2012/066347 patent/WO2013078377A1/en active Application Filing
- 2012-11-21 AU AU2012340623A patent/AU2012340623A1/en not_active Abandoned
- 2012-11-21 RU RU2014124530/10A patent/RU2014124530A/ru not_active Application Discontinuation
- 2012-11-21 SG SG11201402619VA patent/SG11201402619VA/en unknown
- 2012-11-21 BR BR112014012590A patent/BR112014012590A8/pt not_active IP Right Cessation
- 2012-11-21 CN CN201280067876.7A patent/CN104302669A/zh active Pending
- 2012-11-21 EP EP12795978.1A patent/EP2782935A1/en not_active Withdrawn
- 2012-11-21 CA CA2856873A patent/CA2856873A1/en not_active Abandoned
- 2012-11-21 JP JP2014543574A patent/JP2015501639A/ja active Pending
- 2012-11-21 KR KR1020147016959A patent/KR20140125351A/ko not_active Application Discontinuation
-
2014
- 2014-05-22 ZA ZA2014/03760A patent/ZA201403760B/en unknown
- 2014-05-22 IL IL232755A patent/IL232755A0/en unknown
- 2014-05-23 PH PH12014501164A patent/PH12014501164A1/en unknown
-
2015
- 2015-03-31 HK HK15103289.7A patent/HK1202877A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013078377A9 (en) | 2013-08-08 |
| MX2014006272A (es) | 2014-10-24 |
| IL232755A0 (en) | 2014-07-31 |
| NZ626513A (en) | 2017-02-24 |
| JP2015501639A (ja) | 2015-01-19 |
| WO2013078377A1 (en) | 2013-05-30 |
| HK1202877A1 (en) | 2015-10-09 |
| PH12014501164A1 (en) | 2014-10-20 |
| CA2856873A1 (en) | 2013-05-30 |
| AU2012340623A1 (en) | 2014-07-17 |
| EP2782935A1 (en) | 2014-10-01 |
| ZA201403760B (en) | 2017-09-27 |
| SG11201402619VA (en) | 2014-10-30 |
| BR112014012590A2 (pt) | 2017-06-20 |
| KR20140125351A (ko) | 2014-10-28 |
| CN104302669A (zh) | 2015-01-21 |
| BR112014012590A8 (pt) | 2017-12-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20180205 |