RU2004130308A - Применение 6-[3-(1-адамантил)-4-метоксифенил]-2-нафтойной кислоты для лечения дерматологических расстройств - Google Patents

Применение 6-[3-(1-адамантил)-4-метоксифенил]-2-нафтойной кислоты для лечения дерматологических расстройств Download PDF

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RU2004130308A
RU2004130308A RU2004130308/15A RU2004130308A RU2004130308A RU 2004130308 A RU2004130308 A RU 2004130308A RU 2004130308/15 A RU2004130308/15 A RU 2004130308/15A RU 2004130308 A RU2004130308 A RU 2004130308A RU 2004130308 A RU2004130308 A RU 2004130308A
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acne
adapalene
adamantyl
methoxyphenyl
treatment
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RU2004130308/15A
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RU2332208C2 (ru
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Майкл ГРАБЕР (US)
Майкл ГРАБЕР
Януш ЧЕРНЕЛЕВСКИ (FR)
Януш ЧЕРНЕЛЕВСКИ
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Галдерма Ресерч Энд Девелопмент, С.Н.С. (Fr)
Галдерма Ресерч энд Девелопмент, С.Н.С.
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Priority claimed from FR0203070A external-priority patent/FR2837101B1/fr
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Claims (7)

1. Применение 6-[3-(1-адамантил)-4-метоксифенил]-2-нафтойной кислоты (адапалена) или ее солей для получения фармацевтической композиции, предназначенной для лечения дерматологических заболеваний воспалительного или пролиферативного характера, выбранных из обыкновенных угрей, комедональных, полиморфных угрей, узелково-кистозных угрей, шаровидных угрей, вторичных акне, таких как солнечные, медикаментозные или профессиональные угри, обширных и/или тяжелых форм псориаза, ихтиозов и ихтиозоформных состояний, болезни Дарье, ладонно-подошвенной кератодермии, волосяного кератоза и пост-воспалительных пигментаций, отличающееся тем, что фармацевтическая композиция содержит 0,3 вес.% адапалена от общего веса композиции.
2. Применение 6-[3-(1-адамантил)-4-метоксифенил]-2-нафтойной кислоты (адапалена) или ее солей по п.1 для получения фармацевтической композиции, предназначенной для лечения обыкновенных угрей.
3. Применение 6-[3-(1-адамантил)-4-метоксифенил]-2-нафтойной кислоты (адапалена) или ее солей по п. 2 для получения фармацевтической композиции, предназначенной для лечения обыкновенных угрей интенсивности от умеренной до умеренно тяжелой.
4. Применение по п.1, отличающееся тем, что композицию наносят топически.
5. Применение по п.1, отличающееся тем, что композиция находится в виде геля, лосьона или крема.
6. Применение по любому из пп.1-5, отличающееся тем, что композиция является гелем следующей формулы:
Адапален 3 мг Карбомер 940 (BF Goodrich Carbopol 980) 11 мг Двунатриевый эдетат 1 мг Метилпарабен 2 мг Полоксамер 124 2 мг Пропиленгликоль 40 мг Гидроксид натрия: Количество, необходимое для получения pH 5,0±0,3 дистиллированная вода достаточное количество до 1 г
7. Фармацевтическая композиция, содержащая в физиологически приемлемой среде 6-[3-(1-адамантил)-4-метоксифенил]-2-нафтойную кислоту (адапален) или ее соли, предназначенная для лечения дерматологических заболеваний воспалительного или пролиферативного характера, отличающаяся тем, что она содержит 0,3 вес.% адапалена от общего веса композиция.
RU2004130308/15A 2002-03-12 2003-03-12 Применение 6-[3-(1-адамантил)-4-метоксифенил]-2-нафтойной кислоты для лечения дерматологических расстройств RU2332208C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR0203070A FR2837101B1 (fr) 2002-03-12 2002-03-12 Utilisation de l'acide 6-[1-adamantyl)-4-methoxyphenyl]-2- naphthoique pour le traitement de desordres dermatologiques
FR0203070 2002-03-12
US37022302P 2002-04-08 2002-04-08
US60/370,223 2002-04-08

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RU2332208C2 RU2332208C2 (ru) 2008-08-27

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RU2008118056/15A RU2377981C1 (ru) 2002-03-12 2008-05-05 Применение 6-[3-(1-адамантил)-4-метоксифенил]-2-нафтойной кислоты для лечения дерматологических расстройств

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