RS59939B1 - Kombinovana terapija il-2 varijantom imunocitokina sa ciljanim delovanjem na tumor i antitelima na humani pd-l1 - Google Patents
Kombinovana terapija il-2 varijantom imunocitokina sa ciljanim delovanjem na tumor i antitelima na humani pd-l1Info
- Publication number
- RS59939B1 RS59939B1 RS20200202A RSP20200202A RS59939B1 RS 59939 B1 RS59939 B1 RS 59939B1 RS 20200202 A RS20200202 A RS 20200202A RS P20200202 A RSP20200202 A RS P20200202A RS 59939 B1 RS59939 B1 RS 59939B1
- Authority
- RS
- Serbia
- Prior art keywords
- tumor
- targeted
- combination therapy
- antibodies against
- against human
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 238000002648 combination therapy Methods 0.000 title 1
- 229940127130 immunocytokine Drugs 0.000 title 1
Classifications
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2013—IL-2
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- A61K39/0011—Cancer antigens
- A61K39/00118—Cancer antigens from embryonic or fetal origin
- A61K39/001182—Carcinoembryonic antigen [CEA]
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- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Toxicology (AREA)
- Developmental Biology & Embryology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14182778 | 2014-08-29 | ||
PCT/EP2015/069399 WO2016030350A1 (en) | 2014-08-29 | 2015-08-25 | Combination therapy of tumor-targeted il-2 variant immunocytokines and antibodies against human pd-l1 |
EP15753700.2A EP3186283B1 (en) | 2014-08-29 | 2015-08-25 | Combination therapy of tumor-targeted il-2 variant immunocytokines and antibodies against human pd-l1 |
Publications (1)
Publication Number | Publication Date |
---|---|
RS59939B1 true RS59939B1 (sr) | 2020-03-31 |
Family
ID=51535312
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RS20200202A RS59939B1 (sr) | 2014-08-29 | 2015-08-25 | Kombinovana terapija il-2 varijantom imunocitokina sa ciljanim delovanjem na tumor i antitelima na humani pd-l1 |
Country Status (24)
Country | Link |
---|---|
US (3) | US20160175397A1 (sr) |
EP (1) | EP3186283B1 (sr) |
JP (3) | JP6603707B2 (sr) |
KR (1) | KR102058846B1 (sr) |
CN (1) | CN106794245B (sr) |
AR (1) | AR101697A1 (sr) |
AU (1) | AU2015308527C1 (sr) |
BR (1) | BR112016030670A2 (sr) |
CA (1) | CA2951604A1 (sr) |
DK (1) | DK3186283T3 (sr) |
ES (1) | ES2774380T3 (sr) |
HR (1) | HRP20200272T1 (sr) |
HU (1) | HUE047806T2 (sr) |
IL (1) | IL249162B (sr) |
LT (1) | LT3186283T (sr) |
MX (1) | MX2017002426A (sr) |
MY (1) | MY193723A (sr) |
PL (1) | PL3186283T3 (sr) |
PT (1) | PT3186283T (sr) |
RS (1) | RS59939B1 (sr) |
RU (1) | RU2710354C2 (sr) |
SG (1) | SG11201701157UA (sr) |
SI (1) | SI3186283T1 (sr) |
WO (1) | WO2016030350A1 (sr) |
Families Citing this family (103)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108997498A (zh) | 2008-12-09 | 2018-12-14 | 霍夫曼-拉罗奇有限公司 | 抗-pd-l1抗体及它们用于增强t细胞功能的用途 |
EP2655409A4 (en) | 2010-12-22 | 2015-07-01 | Univ Leland Stanford Junior | SUPERAGONISTS AND ANTAGONISTS OF INTERLEUKIN-2 |
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