RS56750B1 - Inhibitorna jedinjenja - Google Patents

Inhibitorna jedinjenja

Info

Publication number
RS56750B1
RS56750B1 RS20171314A RSP20171314A RS56750B1 RS 56750 B1 RS56750 B1 RS 56750B1 RS 20171314 A RS20171314 A RS 20171314A RS P20171314 A RSP20171314 A RS P20171314A RS 56750 B1 RS56750 B1 RS 56750B1
Authority
RS
Serbia
Prior art keywords
inhibitor compounds
inhibitor
compounds
Prior art date
Application number
RS20171314A
Other languages
English (en)
Inventor
Swen Hoelder
Julian Blagg
Savade Solanki
Hannah Woodward
Sebastien Naud
Vassilios Bavetsias
Peter Sheldrake
Paolo Innocenti
Kwai-Ming J Cheung
Butrus Atrash
Original Assignee
Cancer Research Tech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Research Tech Ltd filed Critical Cancer Research Tech Ltd
Publication of RS56750B1 publication Critical patent/RS56750B1/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
RS20171314A 2012-09-07 2013-09-09 Inhibitorna jedinjenja RS56750B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1216017.2A GB201216017D0 (en) 2012-09-07 2012-09-07 Inhibitor compounds
PCT/GB2013/052360 WO2014037750A1 (en) 2012-09-07 2013-09-09 Inhibitor compounds
EP13760106.8A EP2892889B1 (en) 2012-09-07 2013-09-09 Inhibitor compounds

Publications (1)

Publication Number Publication Date
RS56750B1 true RS56750B1 (sr) 2018-03-30

Family

ID=47137117

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20171314A RS56750B1 (sr) 2012-09-07 2013-09-09 Inhibitorna jedinjenja

Country Status (22)

Country Link
US (6) US9409907B2 (sr)
EP (2) EP2892889B1 (sr)
JP (2) JP6216791B2 (sr)
CN (1) CN104837829B (sr)
AU (2) AU2013311434B2 (sr)
BR (1) BR112015004489B1 (sr)
CA (1) CA2884006C (sr)
CY (1) CY1119714T1 (sr)
DK (2) DK3293183T3 (sr)
ES (2) ES2742442T3 (sr)
GB (1) GB201216017D0 (sr)
HK (1) HK1211921A1 (sr)
HR (1) HRP20171835T1 (sr)
HU (1) HUE036259T2 (sr)
LT (1) LT2892889T (sr)
NO (1) NO2892889T3 (sr)
PL (1) PL2892889T3 (sr)
PT (1) PT2892889T (sr)
RS (1) RS56750B1 (sr)
RU (1) RU2673079C2 (sr)
SI (1) SI2892889T1 (sr)
WO (1) WO2014037750A1 (sr)

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Also Published As

Publication number Publication date
AU2013311434A1 (en) 2015-04-02
EP3293183A1 (en) 2018-03-14
RU2015112580A (ru) 2016-10-27
US20160220570A1 (en) 2016-08-04
DK2892889T3 (en) 2017-12-11
US20220402912A1 (en) 2022-12-22
US11897877B2 (en) 2024-02-13
PT2892889T (pt) 2018-01-09
JP6496376B2 (ja) 2019-04-03
JP2015527387A (ja) 2015-09-17
LT2892889T (lt) 2017-12-11
US20200165241A1 (en) 2020-05-28
CA2884006C (en) 2021-01-19
CN104837829B (zh) 2019-07-05
US9890157B2 (en) 2018-02-13
SI2892889T1 (sl) 2017-12-29
AU2017268488B2 (en) 2019-06-13
GB201216017D0 (en) 2012-10-24
US9834552B2 (en) 2017-12-05
HK1211921A1 (en) 2016-06-03
EP2892889B1 (en) 2017-10-18
US20150239884A1 (en) 2015-08-27
US9409907B2 (en) 2016-08-09
EP3293183B1 (en) 2019-07-24
BR112015004489A2 (pt) 2017-07-04
CY1119714T1 (el) 2018-06-27
NO2892889T3 (sr) 2018-03-17
US10479788B2 (en) 2019-11-19
US20180141944A1 (en) 2018-05-24
US20160222009A1 (en) 2016-08-04
CA2884006A1 (en) 2014-03-13
CN104837829A (zh) 2015-08-12
JP2018027967A (ja) 2018-02-22
HRP20171835T1 (hr) 2017-12-29
RU2673079C2 (ru) 2018-11-22
HUE036259T2 (hu) 2018-06-28
ES2742442T3 (es) 2020-02-14
DK3293183T3 (da) 2019-08-12
ES2655194T3 (es) 2018-02-19
WO2014037750A1 (en) 2014-03-13
AU2017268488A1 (en) 2017-12-14
BR112015004489B1 (pt) 2020-09-29
PL2892889T3 (pl) 2018-03-30
AU2013311434B2 (en) 2017-10-19
US11046688B2 (en) 2021-06-29
EP2892889A1 (en) 2015-07-15
JP6216791B2 (ja) 2017-10-18

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