HUE036259T2 - Inhibitor vegyületek - Google Patents
Inhibitor vegyületekInfo
- Publication number
- HUE036259T2 HUE036259T2 HUE13760106A HUE13760106A HUE036259T2 HU E036259 T2 HUE036259 T2 HU E036259T2 HU E13760106 A HUE13760106 A HU E13760106A HU E13760106 A HUE13760106 A HU E13760106A HU E036259 T2 HUE036259 T2 HU E036259T2
- Authority
- HU
- Hungary
- Prior art keywords
- inhibitor compounds
- inhibitor
- compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1216017.2A GB201216017D0 (en) | 2012-09-07 | 2012-09-07 | Inhibitor compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE036259T2 true HUE036259T2 (hu) | 2018-06-28 |
Family
ID=47137117
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE13760106A HUE036259T2 (hu) | 2012-09-07 | 2013-09-09 | Inhibitor vegyületek |
Country Status (22)
Country | Link |
---|---|
US (6) | US9409907B2 (hu) |
EP (2) | EP2892889B1 (hu) |
JP (2) | JP6216791B2 (hu) |
CN (1) | CN104837829B (hu) |
AU (2) | AU2013311434B2 (hu) |
BR (1) | BR112015004489B1 (hu) |
CA (1) | CA2884006C (hu) |
CY (1) | CY1119714T1 (hu) |
DK (2) | DK3293183T3 (hu) |
ES (2) | ES2655194T3 (hu) |
GB (1) | GB201216017D0 (hu) |
HK (1) | HK1211921A1 (hu) |
HR (1) | HRP20171835T1 (hu) |
HU (1) | HUE036259T2 (hu) |
LT (1) | LT2892889T (hu) |
NO (1) | NO2892889T3 (hu) |
PL (1) | PL2892889T3 (hu) |
PT (1) | PT2892889T (hu) |
RS (1) | RS56750B1 (hu) |
RU (1) | RU2673079C2 (hu) |
SI (1) | SI2892889T1 (hu) |
WO (1) | WO2014037750A1 (hu) |
Families Citing this family (24)
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US9017724B2 (en) | 2004-02-24 | 2015-04-28 | The General Hospital Corporation | Catalytic radiofluorination |
CA2978149C (en) | 2008-03-21 | 2019-02-12 | The General Hospital Corporation | Inositol derivatives for the detection and treatment of alzheimer's disease and related disorders |
GB201104267D0 (en) | 2011-03-14 | 2011-04-27 | Cancer Rec Tech Ltd | Pyrrolopyridineamino derivatives |
GB201216017D0 (en) | 2012-09-07 | 2012-10-24 | Cancer Rec Tech Ltd | Inhibitor compounds |
GB201216018D0 (en) | 2012-09-07 | 2012-10-24 | Cancer Rec Tech Ltd | Pharmacologically active compounds |
HUE043465T2 (hu) | 2013-08-23 | 2019-08-28 | Neupharma Inc | Kémiai anyagok, készítmények és módszerek |
GB201403536D0 (en) | 2014-02-28 | 2014-04-16 | Cancer Rec Tech Ltd | Inhibitor compounds |
JP6616934B2 (ja) * | 2014-05-22 | 2019-12-04 | 株式会社 資生堂 | レナリドミドの光学分割方法 |
AU2016220219B2 (en) * | 2015-02-17 | 2020-05-14 | Neupharma, Inc. | Certain chemical entities, compositions, and methods |
AU2016247476B2 (en) | 2015-04-17 | 2021-12-16 | Netherlands Translational Research Center B.V. | Prognostic biomarkers for TTK inhibitor chemotherapy |
EP3305785B1 (en) * | 2015-05-29 | 2021-08-25 | Teijin Pharma Limited | Pyrido[3,4-d]pyrimidine derivative and pharmaceutically acceptable salt thereof |
EP3354653B1 (en) | 2015-07-21 | 2019-09-04 | Guangzhou Maxinovel Pharmaceuticals Co. Ltd. | Fused ring pyrimidine compound, intermediate, and preparation method, composition and use thereof |
GB201522532D0 (en) * | 2015-12-21 | 2016-02-03 | Cancer Rec Tech Ltd | Novel pyrrolo[3,2-c]pyridine-6-amino derivatives |
AU2017312561B2 (en) | 2016-08-15 | 2022-06-30 | Neupharma, Inc. | Certain chemical entities, compositions, and methods |
TWI799399B (zh) * | 2016-11-28 | 2023-04-21 | 日商帝人製藥股份有限公司 | 吡啶并〔3,4-d〕嘧啶衍生物及其藥學上所容許之鹽 |
CA3041854A1 (en) | 2016-11-28 | 2018-05-31 | Teijin Pharma Limited | Crystal of pyrido[3,4-d]pyrimidine derivative or solvate thereof |
GB201709840D0 (en) * | 2017-06-20 | 2017-08-02 | Inst Of Cancer Research: Royal Cancer Hospital | Methods and medical uses |
CN110799183A (zh) * | 2017-06-20 | 2020-02-14 | 癌症研究所:皇家癌症医院 | 方法和医疗用途 |
WO2019081655A1 (en) | 2017-10-26 | 2019-05-02 | CommScope Connectivity Belgium BVBA | TELECOMMUNICATION SYSTEM |
GB201809460D0 (en) | 2018-06-08 | 2018-07-25 | Crt Pioneer Fund Lp | Salt form |
GB201809458D0 (en) | 2018-06-08 | 2018-07-25 | Crt Pioneer Fund Lp | Salt form |
KR102396930B1 (ko) * | 2020-01-15 | 2022-05-12 | 한국과학기술연구원 | 피리도[3,4-d]피리미딘 유도체 및 이를 포함하는 치료용 약학 조성물 |
TW202202498A (zh) * | 2020-07-01 | 2022-01-16 | 大陸商四川海思科製藥有限公司 | 一種並環雜環衍生物及其在醫藥上的應用 |
IL302807A (en) | 2020-11-18 | 2023-07-01 | Deciphera Pharmaceuticals Llc | GCN2 and PERK kinase inhibitors and methods of using them |
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US2697710A (en) | 1953-01-02 | 1954-12-21 | Burroughs Wellcome Co | Pyrido (2,3-d) pyrimidines and method of preparing same |
US3021332A (en) | 1954-01-04 | 1962-02-13 | Burroughs Wellcome Co | Pyrido (2, 3-d) pyrimidine compounds and method of making |
GEP20012444B (en) | 1994-11-14 | 2001-05-25 | Warner Lambert Company Us | 6-Aryl Pyrido[2,3-d]Pyrimidines and Naphthyridines, Pharmaceutical Composition on Their Basis and Application for Inhibiting Cellular Proliferation |
US7053070B2 (en) | 2000-01-25 | 2006-05-30 | Warner-Lambert Company | Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors |
JP4047010B2 (ja) | 2000-01-25 | 2008-02-13 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | ピリド〔2,3−d〕ピリミジン−2,7−ジアミンキナーゼ阻害剤 |
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GB201216018D0 (en) | 2012-09-07 | 2012-10-24 | Cancer Rec Tech Ltd | Pharmacologically active compounds |
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GB201403536D0 (en) | 2014-02-28 | 2014-04-16 | Cancer Rec Tech Ltd | Inhibitor compounds |
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WO2016073771A2 (en) | 2014-11-06 | 2016-05-12 | Ohio State Innovation Foundation | Pyrrolopyrimidine derivatives as mps1/ttk kinase inhibitors |
GB201522532D0 (en) | 2015-12-21 | 2016-02-03 | Cancer Rec Tech Ltd | Novel pyrrolo[3,2-c]pyridine-6-amino derivatives |
GB201709840D0 (en) | 2017-06-20 | 2017-08-02 | Inst Of Cancer Research: Royal Cancer Hospital | Methods and medical uses |
CN110799183A (zh) | 2017-06-20 | 2020-02-14 | 癌症研究所:皇家癌症医院 | 方法和医疗用途 |
-
2012
- 2012-09-07 GB GBGB1216017.2A patent/GB201216017D0/en not_active Ceased
-
2013
- 2013-09-09 DK DK17192253.7T patent/DK3293183T3/da active
- 2013-09-09 SI SI201330829T patent/SI2892889T1/sl unknown
- 2013-09-09 ES ES13760106.8T patent/ES2655194T3/es active Active
- 2013-09-09 RS RS20171314A patent/RS56750B1/sr unknown
- 2013-09-09 EP EP13760106.8A patent/EP2892889B1/en active Active
- 2013-09-09 EP EP17192253.7A patent/EP3293183B1/en active Active
- 2013-09-09 CN CN201380057967.7A patent/CN104837829B/zh active Active
- 2013-09-09 AU AU2013311434A patent/AU2013311434B2/en active Active
- 2013-09-09 CA CA2884006A patent/CA2884006C/en active Active
- 2013-09-09 BR BR112015004489-1A patent/BR112015004489B1/pt active IP Right Grant
- 2013-09-09 JP JP2015530495A patent/JP6216791B2/ja active Active
- 2013-09-09 NO NO13760106A patent/NO2892889T3/no unknown
- 2013-09-09 DK DK13760106.8T patent/DK2892889T3/en active
- 2013-09-09 PL PL13760106T patent/PL2892889T3/pl unknown
- 2013-09-09 ES ES17192253T patent/ES2742442T3/es active Active
- 2013-09-09 US US14/426,549 patent/US9409907B2/en active Active
- 2013-09-09 RU RU2015112580A patent/RU2673079C2/ru active
- 2013-09-09 HU HUE13760106A patent/HUE036259T2/hu unknown
- 2013-09-09 WO PCT/GB2013/052360 patent/WO2014037750A1/en active Application Filing
- 2013-09-09 PT PT137601068T patent/PT2892889T/pt unknown
- 2013-09-09 LT LTEP13760106.8T patent/LT2892889T/lt unknown
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2015
- 2015-12-23 HK HK15112642.0A patent/HK1211921A1/xx unknown
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2016
- 2016-04-06 US US15/091,887 patent/US9890157B2/en active Active
- 2016-04-06 US US15/091,980 patent/US9834552B2/en active Active
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2017
- 2017-09-22 JP JP2017182377A patent/JP6496376B2/ja active Active
- 2017-11-24 HR HRP20171835TT patent/HRP20171835T1/hr unknown
- 2017-11-27 AU AU2017268488A patent/AU2017268488B2/en active Active
- 2017-12-29 CY CY20171101358T patent/CY1119714T1/el unknown
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2018
- 2018-01-08 US US15/864,499 patent/US10479788B2/en active Active
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2019
- 2019-10-10 US US16/598,717 patent/US11046688B2/en active Active
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2021
- 2021-05-13 US US17/319,231 patent/US11897877B2/en active Active
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