RO86355A - Procedeu pentru prepararea(s)-epimerului esterului acidului 7-beta-malonamida-7-alfa-meto0i-3-tetrazoliltiometil-1-detia-1-o0a-3-cefem-4-carbo0ilic - Google Patents

Procedeu pentru prepararea(s)-epimerului esterului acidului 7-beta-malonamida-7-alfa-meto0i-3-tetrazoliltiometil-1-detia-1-o0a-3-cefem-4-carbo0ilic

Info

Publication number
RO86355A
RO86355A RO83111456A RO11145683A RO86355A RO 86355 A RO86355 A RO 86355A RO 83111456 A RO83111456 A RO 83111456A RO 11145683 A RO11145683 A RO 11145683A RO 86355 A RO86355 A RO 86355A
Authority
RO
Romania
Prior art keywords
epemer
dethalyl
tomethyl
malonamide
metho
Prior art date
Application number
RO83111456A
Other languages
English (en)
French (fr)
Other versions
RO86355B (ro
Inventor
Narisada Masayuki
Onue Hiroshi
Ohtani Mitsuaki
Watanabe Fumihiko
Original Assignee
Shionogi & Co Ltd,Jp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co Ltd,Jp filed Critical Shionogi & Co Ltd,Jp
Publication of RO86355A publication Critical patent/RO86355A/ro
Publication of RO86355B publication Critical patent/RO86355B/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
RO111456A 1982-07-02 1983-06-29 Procedeu pentru prepararea(s)-epimerului esterului acidului 7-beta-malonamido-7-alfa-metoxi-3-tetrazoliltiometil-1-detia-1-oxa-3-cefem-4-carboxilic RO86355B (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57116048A JPS597193A (ja) 1982-07-02 1982-07-02 マロニルメチル基の異性化方法

Publications (2)

Publication Number Publication Date
RO86355A true RO86355A (ro) 1985-03-15
RO86355B RO86355B (ro) 1985-03-31

Family

ID=14677411

Family Applications (1)

Application Number Title Priority Date Filing Date
RO111456A RO86355B (ro) 1982-07-02 1983-06-29 Procedeu pentru prepararea(s)-epimerului esterului acidului 7-beta-malonamido-7-alfa-metoxi-3-tetrazoliltiometil-1-detia-1-oxa-3-cefem-4-carboxilic

Country Status (30)

Country Link
US (1) US4504658A (ro)
EP (1) EP0098545B1 (ro)
JP (1) JPS597193A (ro)
KR (1) KR890000812B1 (ro)
AR (1) AR242391A1 (ro)
AT (1) ATE19401T1 (ro)
AU (1) AU564850B2 (ro)
BG (1) BG37526A3 (ro)
CA (1) CA1192193A (ro)
CS (1) CS244940B2 (ro)
DD (1) DD210052A5 (ro)
DE (2) DE3363161D1 (ro)
DK (1) DK160502C (ro)
EG (1) EG16539A (ro)
ES (1) ES8500954A1 (ro)
FI (1) FI832407L (ro)
GB (1) GB2124217B (ro)
GR (1) GR78620B (ro)
HU (1) HU187944B (ro)
IE (1) IE55767B1 (ro)
IL (1) IL69146A (ro)
NO (1) NO832387L (ro)
NZ (1) NZ204627A (ro)
PH (1) PH21139A (ro)
PL (1) PL141782B1 (ro)
PT (1) PT76973B (ro)
RO (1) RO86355B (ro)
SU (1) SU1225488A3 (ro)
YU (1) YU44011B (ro)
ZA (1) ZA834495B (ro)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60123490A (ja) * 1983-12-07 1985-07-02 Shionogi & Co Ltd マロニルオキサセフェムカルボン酸誘導体
US4998060A (en) * 1989-07-12 1991-03-05 Pacific Scientific Company Fault indicator with hot stick clamping mechanism
JP2006028154A (ja) * 2004-06-14 2006-02-02 Sumitomo Chemical Co Ltd 光学活性化合物の製造方法
CN102260280A (zh) * 2010-05-28 2011-11-30 上海医药工业研究院 拉氧头孢钠的制备方法
US9828324B2 (en) 2010-10-20 2017-11-28 Sirrus, Inc. Methylene beta-diketone monomers, methods for making methylene beta-diketone monomers, polymerizable compositions and products formed therefrom
AU2011317050A1 (en) 2010-10-20 2013-05-09 Bioformix, Llc Synthesis of methylene malonates substantially free of impurities
US9279022B1 (en) 2014-09-08 2016-03-08 Sirrus, Inc. Solution polymers including one or more 1,1-disubstituted alkene compounds, solution polymerization methods, and polymer compositions
US9249265B1 (en) 2014-09-08 2016-02-02 Sirrus, Inc. Emulsion polymers including one or more 1,1-disubstituted alkene compounds, emulsion methods, and polymer compositions
US10414839B2 (en) 2010-10-20 2019-09-17 Sirrus, Inc. Polymers including a methylene beta-ketoester and products formed therefrom
WO2013059473A2 (en) 2011-10-19 2013-04-25 Bioformix Inc. Multifunctional monomers, methods for making multifunctional monomers, polymerizable compositions and products formed therefrom
WO2013149173A1 (en) 2012-03-30 2013-10-03 Bioformix Inc. Ink and coating formulations and polymerizable systems for producing the same
CA2869108A1 (en) 2012-03-30 2013-10-03 Bioformix Inc. Methods for activating polymerizable compositions, polymerizable systems, and products formed thereby
WO2013149168A1 (en) 2012-03-30 2013-10-03 Bioformix, Inc. Composite and laminate articles and polymerizable systems for producing the same
US10047192B2 (en) 2012-06-01 2018-08-14 Sirrus, Inc. Optical material and articles formed therefrom
WO2014078689A1 (en) 2012-11-16 2014-05-22 Bioformix Inc. Plastics bonding systems and methods
CN105164797B (zh) 2012-11-30 2019-04-19 瑟拉斯公司 用于电子应用的复合组合物
EP2943462B1 (en) 2013-01-11 2018-06-27 Sirrus, Inc. Method to obtain methylene malonate via bis(hydroxymethyl) malonate pathway
US9315597B2 (en) 2014-09-08 2016-04-19 Sirrus, Inc. Compositions containing 1,1-disubstituted alkene compounds for preparing polymers having enhanced glass transition temperatures
US9416091B1 (en) 2015-02-04 2016-08-16 Sirrus, Inc. Catalytic transesterification of ester compounds with groups reactive under transesterification conditions
US10501400B2 (en) 2015-02-04 2019-12-10 Sirrus, Inc. Heterogeneous catalytic transesterification of ester compounds with groups reactive under transesterification conditions
US9334430B1 (en) 2015-05-29 2016-05-10 Sirrus, Inc. Encapsulated polymerization initiators, polymerization systems and methods using the same
US9217098B1 (en) 2015-06-01 2015-12-22 Sirrus, Inc. Electroinitiated polymerization of compositions having a 1,1-disubstituted alkene compound
US9518001B1 (en) 2016-05-13 2016-12-13 Sirrus, Inc. High purity 1,1-dicarbonyl substituted-1-alkenes and methods for their preparation
US9617377B1 (en) 2016-06-03 2017-04-11 Sirrus, Inc. Polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes
US9567475B1 (en) 2016-06-03 2017-02-14 Sirrus, Inc. Coatings containing polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes
US10428177B2 (en) 2016-06-03 2019-10-01 Sirrus, Inc. Water absorbing or water soluble polymers, intermediate compounds, and methods thereof
US10196481B2 (en) 2016-06-03 2019-02-05 Sirrus, Inc. Polymer and other compounds functionalized with terminal 1,1-disubstituted alkene monomer(s) and methods thereof
KR102115644B1 (ko) * 2017-09-13 2020-05-27 주식회사 동도물산 7α-알콕시옥사세펨 중간체의 제조방법
CN112480147A (zh) * 2019-09-12 2021-03-12 杭州森泽医药科技有限公司 一种拉氧头孢中间体溶剂化物及其制备方法和表征

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3719667A (en) * 1970-08-24 1973-03-06 Lilly Co Eli Epimerization of 6-acylamido and 6-imido penicillin sulfoxide esters
US4167630A (en) * 1975-12-24 1979-09-11 Merck & Co., Inc. Process for epimerizing beta-lactam antibiotic compounds, and related products
CA1085392A (en) * 1976-03-25 1980-09-09 Masayuki Narisada Arylmalonamido-1-oxadethiacephalosporins
US4234596A (en) * 1976-11-19 1980-11-18 Merck & Co., Inc. 3-(2-Aminoethylthio)-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
US4259485A (en) * 1979-04-24 1981-03-31 Eli Lilly And Company Crystallization process
US4252953A (en) * 1979-05-01 1981-02-24 Eli Lilly And Company Antibiotic crystalline epimer
US4320055A (en) * 1980-04-07 1982-03-16 Eli Lilly And Company Process for penicillin epimerization
JPS5711909A (en) * 1980-06-23 1982-01-21 Shionogi & Co Ltd Stable freeze-dried preparation of beta-lactam

Also Published As

Publication number Publication date
GB2124217B (en) 1985-09-04
CS244940B2 (en) 1986-08-14
ES523774A0 (es) 1984-11-01
PL242776A1 (en) 1984-08-13
YU144583A (en) 1986-02-28
EG16539A (en) 1989-03-30
EP0098545A1 (en) 1984-01-18
NO832387L (no) 1984-01-03
US4504658A (en) 1985-03-12
CS503683A2 (en) 1985-09-17
SU1225488A3 (ru) 1986-04-15
JPS597193A (ja) 1984-01-14
DE98545T1 (de) 1984-08-16
PT76973B (en) 1986-01-24
FI832407L (fi) 1984-01-03
GB2124217A (en) 1984-02-15
BG37526A3 (en) 1985-06-14
ES8500954A1 (es) 1984-11-01
NZ204627A (en) 1986-04-11
DK304983A (da) 1984-01-03
DK304983D0 (da) 1983-07-01
DE3363161D1 (en) 1986-05-28
DD210052A5 (de) 1984-05-30
PH21139A (en) 1987-07-27
KR890000812B1 (ko) 1989-04-08
DK160502C (da) 1991-08-26
CA1192193A (en) 1985-08-20
PT76973A (en) 1983-08-01
IL69146A (en) 1987-01-30
IE831527L (en) 1984-01-02
GR78620B (ro) 1984-09-27
AU1649683A (en) 1984-01-05
ZA834495B (en) 1984-07-25
ATE19401T1 (de) 1986-05-15
EP0098545B1 (en) 1986-04-23
AU564850B2 (en) 1987-08-27
IE55767B1 (en) 1991-01-16
YU44011B (en) 1990-02-28
GB8317634D0 (en) 1983-08-03
PL141782B1 (en) 1987-08-31
AR242391A1 (es) 1993-03-31
RO86355B (ro) 1985-03-31
KR840005450A (ko) 1984-11-12
JPH0149271B2 (ro) 1989-10-24
DK160502B (da) 1991-03-18
FI832407A0 (fi) 1983-06-30
HU187944B (en) 1986-03-28

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