PT906338E - Analogos do peptido 2 do tipo glucagon - Google Patents

Analogos do peptido 2 do tipo glucagon

Info

Publication number
PT906338E
PT906338E PT97916280T PT97916280T PT906338E PT 906338 E PT906338 E PT 906338E PT 97916280 T PT97916280 T PT 97916280T PT 97916280 T PT97916280 T PT 97916280T PT 906338 E PT906338 E PT 906338E
Authority
PT
Portugal
Prior art keywords
peptide analogs
glucagon
glucagon type
type
analogs
Prior art date
Application number
PT97916280T
Other languages
English (en)
Inventor
Martin Sumner-Smith
Daniel J Drucker
Anna E Crivici
Original Assignee
Ontario Inc 1149336
Allelix Biopharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24530501&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT906338(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ontario Inc 1149336, Allelix Biopharma filed Critical Ontario Inc 1149336
Publication of PT906338E publication Critical patent/PT906338E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/605Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PT97916280T 1996-04-12 1997-04-11 Analogos do peptido 2 do tipo glucagon PT906338E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63127396A 1996-04-12 1996-04-12

Publications (1)

Publication Number Publication Date
PT906338E true PT906338E (pt) 2003-03-31

Family

ID=24530501

Family Applications (2)

Application Number Title Priority Date Filing Date
PT97916280T PT906338E (pt) 1996-04-12 1997-04-11 Analogos do peptido 2 do tipo glucagon
PT01129072T PT1231219E (pt) 1996-04-12 2001-12-07 Análogos do péptido semelhante a glucagon-2

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT01129072T PT1231219E (pt) 1996-04-12 2001-12-07 Análogos do péptido semelhante a glucagon-2

Country Status (16)

Country Link
EP (5) EP0906338B1 (pt)
JP (3) JP4148994B2 (pt)
CN (1) CN1268640C (pt)
AT (2) ATE227309T1 (pt)
AU (1) AU733857B2 (pt)
BR (1) BRPI9708566B8 (pt)
CA (1) CA2251576C (pt)
DE (2) DE69716905T2 (pt)
DK (2) DK0906338T3 (pt)
ES (2) ES2351661T3 (pt)
FR (1) FR13C0013I2 (pt)
HK (3) HK1033324A1 (pt)
LU (1) LU92153I2 (pt)
NZ (1) NZ332281A (pt)
PT (2) PT906338E (pt)
WO (1) WO1997039031A1 (pt)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6184201B1 (en) 1995-04-14 2001-02-06 Nps Allelix Corp. Intestinotrophic glucagon-like peptide-2 analogs
US5990077A (en) * 1995-04-14 1999-11-23 1149336 Ontario Inc. Glucagon-like peptide-2 and its therapeutic use
US5834428A (en) 1995-04-14 1998-11-10 1149336 Ontario Inc. Glucagon-like peptide-2 and its therapeutic use
US6852690B1 (en) 1995-08-22 2005-02-08 Amylin Pharmaceuticals, Inc. Method and composition for enhanced parenteral nutrition
DE69716905T2 (de) * 1996-04-12 2003-07-24 1149336 Ontario Inc., Toronto Analoge des glucagon ähnlichen peptides -2
US5952301A (en) * 1996-12-10 1999-09-14 1149336 Ontario Inc. Compositions and methods for enhancing intestinal function
CA2236519C (en) 1997-05-02 2011-09-13 1149336 Ontario Inc. Methods of enhancing functioning of the large intestine
CA2289652C (en) * 1997-05-16 2012-02-28 1149336 Ontario Inc. Methods of enhancing functioning of the upper gastrointestinal tract
EP1060192A2 (en) * 1998-02-27 2000-12-20 Novo Nordisk A/S Glp-2 derivatives with helix-content exceeding 25 %, forming partially structured micellar-like aggregates
AU7421598A (en) * 1998-05-11 1999-11-29 1149336 Ontario Inc. Methods of enhancing functioning of the large intestine
GB9930882D0 (en) 1999-12-30 2000-02-23 Nps Allelix Corp GLP-2 formulations
DE60134251D1 (de) 2000-09-18 2008-07-10 Sanos Bioscience As Verwendung von glp-2-peptiden
US7371721B2 (en) 2000-09-18 2008-05-13 Sanos Bioscience A/S Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes
US7411039B2 (en) 2002-10-14 2008-08-12 Novo Nordisk A/S GLP-2 compounds, formulations, and uses thereof
ATE502665T1 (de) 2003-02-04 2011-04-15 Novo Nordisk As Injektionsvorrichtung mit drehbarer dosiseinstellungsvorrichtung
PL1664109T3 (pl) * 2003-08-21 2010-01-29 Novo Nordisk As Oczyszczanie peptydów glukagonopodobnych
EP2842576B1 (en) 2004-01-21 2017-06-28 Novo Nordisk Health Care AG Transglutaminase mediated conjugation of peptides
JP5197012B2 (ja) 2004-11-01 2013-05-15 エヌピーエス ファーマシューティカルズ インコーポレイテッド 大腸連続性を伴う短腸症候群患者の治療
CN102659938B (zh) 2005-05-04 2016-01-20 西兰制药公司 胰高血糖素样肽-2(glp-2)类似物
CN100418983C (zh) * 2005-05-11 2008-09-17 中国药科大学 人胰高血糖素相关肽-2类似物
AU2007319066B2 (en) * 2006-11-08 2013-09-19 Zealand Pharma A/S Selective glucagon-like-peptide-2 (GLP-2) analogues
CN101824087A (zh) * 2009-03-05 2010-09-08 连云港恒邦医药科技有限公司 胰高血糖素样肽-2类似物及其制备方法和用途
EP2311486A1 (en) * 2009-10-07 2011-04-20 Nestec S.A. GLP-2 for use in intestine and muscle recovery
EP2314616A1 (en) * 2009-10-23 2011-04-27 Ferring B.V. Peptidic GLP-2 agonists
RU2012122162A (ru) * 2009-10-30 2013-12-10 Глитек,Инк. Гликолизированная форма аналога антигенного glp-1
US9782454B2 (en) 2010-04-22 2017-10-10 Longevity Biotech, Inc. Highly active polypeptides and methods of making and using the same
JP2013526535A (ja) * 2010-05-11 2013-06-24 エヌピーエス ファーマシューティカルズ インコーポレイテッド 腎機能障害または肝機能障害の治療または予防のための方法
WO2012131109A2 (en) 2011-04-01 2012-10-04 Max-Planck-Gesellschaft zur Förderung der Wissenschaft e.V. Peptides and pharmaceutical compositions for use in the treatment by nasal administration of patients suffering from anxiety and sleep disorders
CN102924589B (zh) * 2011-08-11 2016-08-24 中肽生化有限公司 胰高血糖素样肽-2(glp-2)的类似物及其制备方法和用途
EA028929B1 (ru) 2012-05-03 2018-01-31 Зилэнд Фарма А/С Аналоги глюкагоноподобного пептида-2 (glp-2)
CN103159848B (zh) * 2013-01-06 2015-11-25 中国人民解放军第四军医大学 人胰高血糖素样肽-2二串体蛋白及其制备方法
US9789164B2 (en) 2013-03-15 2017-10-17 Longevity Biotech, Inc. Peptides comprising non-natural amino acids and methods of making and using the same
US10774127B2 (en) 2016-10-12 2020-09-15 University Of Copenhagen Peptide dual agonists of GIPR and GLP2R
PE20191083A1 (es) 2016-12-09 2019-08-20 Zealand Pharma As Agonistas duales acilados de glp-1/glp-2
WO2019086559A1 (fr) 2017-10-31 2019-05-09 Adocia Composition comprenant un agoniste du recepteur du glp-2 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes
WO2020020904A1 (en) 2018-07-23 2020-01-30 Zealand Pharma A/S Therapeutic uses of glp-2 agonists
EP3628682A1 (en) 2018-09-28 2020-04-01 Zealand Pharma A/S Formulations of glucagon-like-peptide-2 (glp-2) analogues
EP3628683A1 (en) 2018-09-28 2020-04-01 Zealand Pharma A/S Formulations of glucagon-like-peptide-2 (glp-2) analogues
EP3924369A1 (en) 2019-02-11 2021-12-22 OPKO Biologics Ltd. Long-acting glp-2 analogs
JP2022552655A (ja) 2019-10-07 2022-12-19 キャリーオペ,インク. Gpr119アゴニスト
WO2021198195A1 (en) 2020-03-30 2021-10-07 Zealand Pharma A/S Agonist combination
CA3240750A1 (en) * 2021-12-17 2023-06-22 Bainan Biotech Aps Peptide dual agonists of gipr and glp2r

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5186117A (en) 1975-01-27 1976-07-28 Tanabe Seiyaku Co Johoseibiryushiseizainoseiho
GB1575343A (en) 1977-05-10 1980-09-17 Ici Ltd Method for preparing liposome compositions containing biologically active compounds
US4529561A (en) 1978-03-24 1985-07-16 The Regents Of The University Of California Method for producing liposomes in selected size range
GB2046092B (en) 1979-03-05 1983-11-02 Toyama Chemical Co Ltd Pharmaceutical composition containing a lysophospholid and a phospholipid
US4452747A (en) 1982-03-22 1984-06-05 Klaus Gersonde Method of and arrangement for producing lipid vesicles
US4725442A (en) 1983-06-17 1988-02-16 Haynes Duncan H Microdroplets of water-insoluble drugs and injectable formulations containing same
US5008050A (en) 1984-06-20 1991-04-16 The Liposome Company, Inc. Extrusion technique for producing unilamellar vesicles
US4921706A (en) 1984-11-20 1990-05-01 Massachusetts Institute Of Technology Unilamellar lipid vesicles and method for their formation
US4737323A (en) 1986-02-13 1988-04-12 Liposome Technology, Inc. Liposome extrusion method
US4920016A (en) 1986-12-24 1990-04-24 Linear Technology, Inc. Liposomes with enhanced circulation time
US5009956A (en) 1987-02-24 1991-04-23 Univ Minnesota Phospholipase A2-resistant liposomes
US4927637A (en) 1989-01-17 1990-05-22 Liposome Technology, Inc. Liposome extrusion method
US4944948A (en) 1989-02-24 1990-07-31 Liposome Technology, Inc. EGF/Liposome gel composition and method
JP2961045B2 (ja) * 1993-02-24 1999-10-12 日清製粉株式会社 腸管粘膜増強促進剤
CA2137206A1 (en) 1993-12-09 1995-06-10 John A. Galloway Glucagon-like insulinotropic peptides, compositions and methods
US5990077A (en) 1995-04-14 1999-11-23 1149336 Ontario Inc. Glucagon-like peptide-2 and its therapeutic use
CZ297338B6 (cs) 1996-03-01 2006-11-15 Novo Nordisk A/S Peptid potlacující chut k jídlu, farmaceutický prostredek jej obsahující a jeho pouzití
DE69716905T2 (de) * 1996-04-12 2003-07-24 1149336 Ontario Inc., Toronto Analoge des glucagon ähnlichen peptides -2
US5994500A (en) 1996-07-19 1999-11-30 1149336 Ontario Inc. Antagonists of intestinotrophic GLP-2 peptides
WO2002066062A2 (en) 2001-02-01 2002-08-29 Drucker Daniel J Enhancement of glp-2 activity

Also Published As

Publication number Publication date
AU733857B2 (en) 2001-05-31
DK1231219T3 (da) 2010-12-20
WO1997039031A1 (en) 1997-10-23
DE60142885D1 (de) 2010-10-07
EP1231219B1 (en) 2010-08-25
JP4148994B2 (ja) 2008-09-10
CN1268640C (zh) 2006-08-09
EP1231219A1 (en) 2002-08-14
EP2009024A1 (en) 2008-12-31
LU92153I2 (fr) 2013-04-19
DK0906338T3 (da) 2003-03-03
HK1050204A1 (en) 2003-06-13
FR13C0013I2 (fr) 2013-08-16
HK1147761A1 (en) 2011-08-19
BRPI9708566B8 (pt) 2022-01-18
BR9708566B1 (pt) 2012-09-04
ATE227309T1 (de) 2002-11-15
DE69716905D1 (de) 2002-12-12
EP0906338B1 (en) 2002-11-06
JP5019466B2 (ja) 2012-09-05
JP2007204491A (ja) 2007-08-16
BRPI9708566A (pt) 2000-01-04
CA2251576A1 (en) 1997-10-23
CA2251576C (en) 2012-08-21
DE69716905T2 (de) 2003-07-24
EP2275438A1 (en) 2011-01-19
EP2218734A2 (en) 2010-08-18
JP4149497B2 (ja) 2008-09-10
EP2218734B1 (en) 2013-06-05
ES2351661T3 (es) 2011-02-09
JP2008184465A (ja) 2008-08-14
HK1033324A1 (en) 2001-08-24
NZ332281A (en) 2000-03-27
AU2500297A (en) 1997-11-07
EP0906338A1 (en) 1999-04-07
JP2000511881A (ja) 2000-09-12
HK1050204B (zh) 2011-09-23
ES2188929T3 (es) 2003-07-01
CN1244872A (zh) 2000-02-16
FR13C0013I1 (pt) 2013-05-04
ATE478892T1 (de) 2010-09-15
EP2218734A3 (en) 2010-10-13
PT1231219E (pt) 2010-11-30

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