PT788511E - Hexapeptidos ciclicos com actividade antibiotica - Google Patents

Hexapeptidos ciclicos com actividade antibiotica

Info

Publication number
PT788511E
PT788511E PT95932935T PT95932935T PT788511E PT 788511 E PT788511 E PT 788511E PT 95932935 T PT95932935 T PT 95932935T PT 95932935 T PT95932935 T PT 95932935T PT 788511 E PT788511 E PT 788511E
Authority
PT
Portugal
Prior art keywords
hexapeptides
cycle
antibiotic activity
antibiotic
activity
Prior art date
Application number
PT95932935T
Other languages
English (en)
Inventor
Hisashi Takasugi
Masaki Tomishima
Akira Yamada
Hidenori Ohki
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26305774&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT788511(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB9420425A external-priority patent/GB9420425D0/en
Priority claimed from GBGB9508745.8A external-priority patent/GB9508745D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of PT788511E publication Critical patent/PT788511E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT95932935T 1994-10-07 1995-09-29 Hexapeptidos ciclicos com actividade antibiotica PT788511E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9420425A GB9420425D0 (en) 1994-10-07 1994-10-07 New compound
GBGB9508745.8A GB9508745D0 (en) 1995-04-28 1995-04-28 New compound

Publications (1)

Publication Number Publication Date
PT788511E true PT788511E (pt) 2003-04-30

Family

ID=26305774

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95932935T PT788511E (pt) 1994-10-07 1995-09-29 Hexapeptidos ciclicos com actividade antibiotica

Country Status (27)

Country Link
US (2) US6107458A (pt)
EP (1) EP0788511B1 (pt)
JP (2) JP2897427B2 (pt)
KR (1) KR100353303B1 (pt)
CN (1) CN1203089C (pt)
AR (1) AR041770A1 (pt)
AT (1) ATE229541T1 (pt)
AU (1) AU696949B2 (pt)
BR (2) BRPI9504791B8 (pt)
CA (1) CA2202058C (pt)
DE (2) DE122008000025I2 (pt)
DK (1) DK0788511T3 (pt)
ES (1) ES2187575T3 (pt)
FI (1) FI119988B (pt)
FR (1) FR08C0028I2 (pt)
HK (1) HK1004136A1 (pt)
HU (1) HU228151B1 (pt)
IL (1) IL115484A (pt)
LU (1) LU91452I2 (pt)
MX (1) MX9702531A (pt)
NL (1) NL300352I2 (pt)
NO (2) NO328483B1 (pt)
OA (1) OA10475A (pt)
PT (1) PT788511E (pt)
RU (1) RU2165423C2 (pt)
TR (1) TR199501229A2 (pt)
WO (1) WO1996011210A1 (pt)

Families Citing this family (58)

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US5696084A (en) * 1996-08-16 1997-12-09 Abbott Laboratories Amino-lipopetide antifungal agents
AUPO371596A0 (en) * 1996-11-19 1996-12-12 Fujisawa Pharmaceutical Co., Ltd. New compound
AUPO381496A0 (en) * 1996-11-25 1996-12-19 Fujisawa Pharmaceutical Co., Ltd. New compound
US6291680B1 (en) * 1997-06-18 2001-09-18 Fujisawa Pharmaceutical Co., Ltd. Production process
AU756792B2 (en) * 1998-02-09 2003-01-23 Fujisawa Pharmaceutical Co., Ltd. New compound
KR100396737B1 (ko) * 1998-02-09 2003-09-13 후지사와 야꾸힝 고교 가부시키가이샤 신규 화합물
US7084279B1 (en) * 1999-02-11 2006-08-01 Emisphere Technologies Inc. Oxadiazole compounds and compositions for delivering active agents
DE60024414T2 (de) * 1999-02-11 2006-06-14 Emisphere Tech Inc Oxadiazolverbindungen und -zusammensetzungen zur abgabe von wirkstoffen
AUPP999799A0 (en) * 1999-04-27 1999-05-20 Fujisawa Pharmaceutical Co., Ltd. New compound
AUPQ066399A0 (en) * 1999-05-31 1999-06-24 Fujisawa Pharmaceutical Co., Ltd. Antifungal combination use
TWI233805B (en) * 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent
WO2001007468A2 (en) * 1999-07-27 2001-02-01 Aventis Pharma Deutschland Gmbh Novel cyclohexapeptide compounds, processes for their production and their use as a pharmaceutical
AUPQ462399A0 (en) * 1999-12-13 2000-01-13 Fujisawa Pharmaceutical Co., Ltd. New use
TWI250992B (en) * 2000-02-21 2006-03-11 Astellas Pharma Inc Polypeptide compounds for the prophylactic and/or therapeutic treatment of infectious diseases caused by pathogenic microorganisms
ES2191516B1 (es) * 2000-07-28 2005-01-01 Consejo Superior De Investigaciones Cientificas Antibioticos antifungicos de naturaleza peptidica inhibidores de la germinacion y el crecimiento de hongos fitopatogenos.
AUPQ938700A0 (en) * 2000-08-14 2000-09-07 Fujisawa Pharmaceutical Co., Ltd. Antifungal combination use
US7867516B2 (en) 2001-01-29 2011-01-11 Shionogi & Co., Ltd. Medicinal preparation containing 5-methyl-1-phenyl-2-(1h)-pyridone as active ingredient
JP2005053782A (ja) * 2001-08-31 2005-03-03 Fujisawa Pharmaceut Co Ltd 環状リポペプチド化合物の新規結晶
EP2266590A3 (en) 2002-02-22 2011-04-20 Shire LLC Active agent delivery sytems and methods for protecting and administering active agents
US7199248B2 (en) 2002-08-08 2007-04-03 Astellas Pharma Inc. Process
AU2003903205A0 (en) * 2003-06-23 2003-07-10 Fujisawa Pharmaceutical Co., Ltd. New compound
DE602004010915T2 (de) * 2003-07-22 2008-12-11 Theravance, Inc., South San Francisco Verwendung eines antimykotischen echinocandin-mittels in kombination mit einem antibakteriellen glycopeptid-mittel
US20070010655A1 (en) * 2003-09-05 2007-01-11 Antia Firoz D Stationary phases and a purification process using the stationary phases
CA2551037A1 (en) * 2003-09-22 2005-03-31 Banyu Pharmaceutical Co., Ltd. Novel piperidine derivative
US7476673B2 (en) * 2003-12-30 2009-01-13 Allergan, Inc. Disubstituted chalcone oximes as selective agonists of RARγ retinoid receptors
MXPA06013381A (es) * 2004-05-20 2007-03-01 Scripps Research Inst Estabilizacion de transtiretina.
JP4958786B2 (ja) 2004-09-20 2012-06-20 ゼノン・ファーマシューティカルズ・インコーポレイテッド 複素環誘導体および治療薬としてのそれらの使用
TW200626138A (en) 2004-09-20 2006-08-01 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
AR051091A1 (es) 2004-09-20 2006-12-20 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
WO2006034441A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
AU2005329423A1 (en) 2004-09-20 2006-09-28 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
CN101083982A (zh) 2004-09-20 2007-12-05 泽农医药公司 用于治疗硬脂酰CoA去饱和酶介导的疾病的杂环衍生物
CN101083992A (zh) 2004-09-20 2007-12-05 泽农医药公司 抑制人硬脂酰CoA去饱和酶的哒嗪衍生物
US9315467B2 (en) * 2004-10-13 2016-04-19 Ptc Therapeutics, Inc. Compounds for nonsense suppression, and methods for their use
MX2007015216A (es) 2005-06-03 2008-02-22 Xenon Pharmaceuticals Inc Derivados de aminotiazol y sus usos como agentes terapeuticos.
KR20080066938A (ko) * 2005-10-07 2008-07-17 깃세이 야쿠힌 고교 가부시키가이샤 질소 함유 복소환 화합물 및 그것을 함유하는 의약 조성물
CN101516387B (zh) * 2006-07-26 2014-06-04 桑多斯股份公司 卡泊芬净制剂
US8853392B2 (en) 2007-06-03 2014-10-07 Vanderbilt University Benzamide mGluR5 positive allosteric modulators and methods of making and using same
HUE035249T2 (en) 2007-08-13 2018-05-02 Monsanto Technology Llc Preparations and procedures for controlling nematodes
EP2204379A4 (en) * 2007-10-29 2010-12-22 Astellas Pharma Inc POLYPEPTIDE COMPOUND
US8034806B2 (en) 2007-11-02 2011-10-11 Vanderbilt University Bicyclic mGluR5 positive allosteric modulators and methods of making and using same
MX2010014569A (es) * 2008-06-24 2011-03-29 Irm Llc Compuestos y metodos para modular los receptores acoplados con proteina-g.
US9394340B2 (en) 2009-03-24 2016-07-19 Cadila Healthcare Limited Purification process for lipopeptides
BR112013023531A2 (pt) * 2011-04-04 2016-12-06 Xellia Pharmaceuticals Aps processo de um único vaso para a fabricação de micafungina ou de um sal desta
EP2918324A1 (en) 2011-04-20 2015-09-16 Xellia Pharmaceuticals ApS Method for purification of micafungin
CN102775476B (zh) 2011-05-12 2015-01-07 上海天伟生物制药有限公司 一种米卡芬净钠盐的制备方法
WO2012158844A1 (en) 2011-05-17 2012-11-22 Shionogi & Co., Ltd. Heterocyclic compounds
RU2014113624A (ru) * 2011-09-09 2015-10-20 Сандоз Аг Получение промежуточных продуктов для получения микафунгина
CN102627688B (zh) 2012-03-30 2014-12-31 上海天伟生物制药有限公司 一种高纯度环肽化合物及其制备方法和用途
CN102659930B (zh) * 2012-03-30 2014-04-23 上海天伟生物制药有限公司 一种高纯度环肽类物质的晶体及其制备方法和用途
CN102627689B (zh) * 2012-03-30 2014-08-06 上海天伟生物制药有限公司 一种环肽类化合物的水合物及其制备方法和用途
WO2015180682A1 (zh) * 2014-05-29 2015-12-03 上海天伟生物制药有限公司 一种环肽类化合物的溶剂合物及其制备方法和用途
WO2016056023A2 (en) * 2014-10-07 2016-04-14 Alaparthi Lakshmi Prasad Intermediates and processes to prepare micafungin
CA2937365C (en) 2016-03-29 2018-09-18 F. Hoffmann-La Roche Ag Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same
EP3485873A1 (en) 2017-11-17 2019-05-22 Cadila Healthcare Limited Stable pharmaceutical injectable compositions of micafungin
CN113087775B (zh) * 2018-05-31 2022-07-08 杭州中美华东制药有限公司 米卡芬净钠新晶型ii及其制备方法
WO2020013116A1 (ja) * 2018-07-10 2020-01-16 京都薬品工業株式会社 Ｐｔｐ－１ｂ阻害剤およびその用途
CN110734408A (zh) * 2019-10-22 2020-01-31 重庆康乐制药有限公司 一种米卡芬净类衍生物侧链中间体的制备方法

Family Cites Families (2)

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IL98506A (en) * 1990-06-18 1996-09-12 Fujisawa Pharmaceutical Co Peptides, of antibiotics, processes for their preparation and pharmaceutical preparations containing them
IL105048A (en) * 1992-03-19 2001-06-14 Eli Lilly And Company U S Antifungal substances of the cyclic peptide type and a process for their preparation

Also Published As

Publication number Publication date
FI971397A0 (fi) 1997-04-04
AU696949B2 (en) 1998-09-24
NO2010016I1 (no) 2010-08-16
FI119988B (fi) 2009-05-29
KR970707150A (ko) 1997-12-01
TR199501229A2 (tr) 1996-07-21
CN1168675A (zh) 1997-12-24
DE122008000025I2 (de) 2011-02-17
FI971397A (fi) 1997-05-27
DE69529172T2 (de) 2003-04-17
NO971544L (no) 1997-06-04
US6265536B1 (en) 2001-07-24
CN1203089C (zh) 2005-05-25
IL115484A (en) 2000-07-16
ES2187575T3 (es) 2003-06-16
JP2897427B2 (ja) 1999-05-31
FR08C0028I1 (pt) 2008-08-15
MX9702531A (es) 1997-06-28
OA10475A (en) 2002-04-08
NL300352I1 (nl) 2008-08-01
CA2202058C (en) 2007-11-06
AU3578095A (en) 1996-05-02
CA2202058A1 (en) 1996-04-18
BRPI9504791B8 (pt) 2019-12-31
DK0788511T3 (da) 2003-03-31
JP3518665B2 (ja) 2004-04-12
RU2165423C2 (ru) 2001-04-20
HK1004136A1 (en) 1998-11-20
HUT77736A (hu) 1998-07-28
US6107458A (en) 2000-08-22
EP0788511A1 (en) 1997-08-13
ATE229541T1 (de) 2002-12-15
LU91452I2 (fr) 2008-08-04
NL300352I2 (nl) 2008-11-03
JPH10507174A (ja) 1998-07-14
WO1996011210A1 (en) 1996-04-18
HU228151B1 (en) 2012-12-28
NO2010016I2 (no) 2011-10-17
KR100353303B1 (ko) 2003-01-15
FR08C0028I2 (pt) 2009-11-20
IL115484A0 (en) 1996-01-19
JPH10324695A (ja) 1998-12-08
AR041770A1 (es) 2005-06-01
EP0788511B1 (en) 2002-12-11
BR9504791A (pt) 1996-10-22
BR9504791B1 (pt) 2010-10-05
DE122008000025I1 (de) 2008-08-21
DE69529172D1 (de) 2003-01-23
NO971544D0 (no) 1997-04-04
NO328483B1 (no) 2010-03-01

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