PT739417E - Producao de l-isoleucina atraves de microrganismos recombinantes com treonina desidratase desregulada - Google Patents
Producao de l-isoleucina atraves de microrganismos recombinantes com treonina desidratase desreguladaInfo
- Publication number
- PT739417E PT739417E PT95905043T PT95905043T PT739417E PT 739417 E PT739417 E PT 739417E PT 95905043 T PT95905043 T PT 95905043T PT 95905043 T PT95905043 T PT 95905043T PT 739417 E PT739417 E PT 739417E
- Authority
- PT
- Portugal
- Prior art keywords
- enzyme
- isoleucine
- pct
- amino acid
- gene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4400926A DE4400926C1 (de) | 1994-01-14 | 1994-01-14 | Herstellung von L-Isoleucin mittels rekombinanter Mikroorganismen mit deregulierter Threonindehydratase |
Publications (1)
Publication Number | Publication Date |
---|---|
PT739417E true PT739417E (pt) | 2004-02-27 |
Family
ID=6507920
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT95905043T PT739417E (pt) | 1994-01-14 | 1995-01-09 | Producao de l-isoleucina atraves de microrganismos recombinantes com treonina desidratase desregulada |
Country Status (9)
Country | Link |
---|---|
US (1) | US6107063A (pt) |
EP (1) | EP0739417B1 (pt) |
JP (1) | JP4471402B2 (pt) |
AT (1) | ATE248921T1 (pt) |
DE (2) | DE4400926C1 (pt) |
DK (1) | DK0739417T3 (pt) |
ES (1) | ES2206488T3 (pt) |
PT (1) | PT739417E (pt) |
WO (1) | WO1995019442A1 (pt) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6696561B1 (en) | 1909-07-09 | 2004-02-24 | Basf Aktiengesellschaft | Corynebacterium glutamicum genes encoding proteins involved in membrane synthesis and membrane transport |
DE19548222A1 (de) * | 1995-12-22 | 1997-06-26 | Forschungszentrum Juelich Gmbh | Verfahren zur mikrobiellen Herstellung von Aminosäuren durch gesteigerte Aktivität von Exportcarriern |
US5959179A (en) * | 1996-03-13 | 1999-09-28 | Monsanto Company | Method for transforming soybeans |
US6946588B2 (en) | 1996-03-13 | 2005-09-20 | Monsanto Technology Llc | Nucleic acid encoding a modified threonine deaminase and methods of use |
US5958745A (en) * | 1996-03-13 | 1999-09-28 | Monsanto Company | Methods of optimizing substrate pools and biosynthesis of poly-β-hydroxybutyrate-co-poly-β-hydroxyvalerate in bacteria and plants |
CA2296759A1 (en) * | 1997-07-10 | 1999-01-21 | Purdue Research Foundation | Methods and compositions for producing plants and microorganisms that express feedback insensitive threonine dehydratase/deaminase |
DE19907567B4 (de) * | 1999-02-22 | 2007-08-09 | Forschungszentrum Jülich GmbH | Verfahren zur mikrobiellen Herstellung von L-Valin |
KR100834991B1 (ko) | 1999-06-25 | 2008-06-05 | 백광산업 주식회사 | 대사 경로 단백질을 코딩하는 코리네박테리움 글루타미쿰유전자 |
US7270984B1 (en) | 1999-06-25 | 2007-09-18 | Basf Aktiengesellschaft | Polynucleotides encoding a 6-phosphogluconolactonase polypeptide from corynebacterium glutamicum |
US6884614B1 (en) | 1999-07-01 | 2005-04-26 | Basf Aktiengesellschaft | Corynebacterium glutamicum genes encoding phosphoenolpyruvate: sugar phosphotransferase system proteins |
DE19953206A1 (de) | 1999-11-05 | 2001-05-10 | Degussa | Plasmide aus Corynebacterium glutamicum und deren Verwendung |
KR100451299B1 (ko) * | 2002-03-21 | 2004-10-06 | 씨제이 주식회사 | L―쓰레오닌의 제조방법 |
EP2216405A1 (en) | 2002-05-03 | 2010-08-11 | Monsanto Technology LLC | Speed specific USP promoters for expressing genes in plants |
US7078234B2 (en) | 2002-12-18 | 2006-07-18 | Monsanto Technology Llc | Maize embryo-specific promoter compositions and methods for use thereof |
EP2116606B1 (en) | 2003-03-28 | 2012-12-19 | Monsanto Technology, LLC | Novel plant promoters for use in early seed development |
KR100498971B1 (ko) * | 2003-04-04 | 2005-07-04 | 씨제이 주식회사 | 염색체 내 tdcBC 및 pckA 유전자가 불활성화된 미생물 및 이를 이용하여 L-쓰레오닌을 제조하는 방법 |
AU2003258886A1 (en) * | 2003-09-06 | 2005-03-29 | Cj Corporation | A method for producing l-threonine |
EP1856264B1 (en) | 2005-02-26 | 2014-07-23 | BASF Plant Science GmbH | Expression cassettes for seed-preferential expression in plants |
CA2606220A1 (en) | 2005-04-19 | 2006-12-21 | Basf Plant Science Gmbh | Starchy-endosperm and/or germinating embryo-specific expression in mono-cotyledonous plants |
EP2151498A3 (en) | 2005-04-20 | 2010-12-15 | BASF Plant Science GmbH | Expression cassettes for seed-preferential expression in plants |
AU2006245701B2 (en) | 2005-05-10 | 2011-04-28 | Basf Plant Science Gmbh | Expression cassettes for seed-preferential expression in plants |
DE102006050489A1 (de) | 2006-10-26 | 2008-04-30 | Evonik Degussa Gmbh | Allele des prpD1-Gens aus coryneformen Bakterien |
US20110035840A1 (en) | 2007-02-16 | 2011-02-10 | Basf Plant Science Gmbh | Nucleic acid sequences for regulation of embryo-specific expression in monocotyledoneous plants |
WO2010118477A1 (en) | 2009-04-17 | 2010-10-21 | Molecular Plant Breeding Nominees Ltd | Plant promoter operable in endosperm and uses thereof |
WO2011003901A1 (en) | 2009-07-10 | 2011-01-13 | Basf Plant Science Company Gmbh | Expression cassettes for endosperm-specific expression in plants |
AU2010325720A1 (en) | 2009-12-03 | 2012-07-19 | Basf Plant Science Company Gmbh | Expression cassettes for embryo-specific expression in plants |
CN106701853B (zh) * | 2016-12-02 | 2019-09-20 | 武汉远大弘元股份有限公司 | 一种产l-异亮氨酸谷氨酸棒杆菌发酵培养基及培养方法 |
US11639512B2 (en) | 2017-03-21 | 2023-05-02 | Wuhan Grand Hoyo Co., Ltd. | Corynebacterium constitutive expression vector promoter screened on the basis of transcriptome sequencing, screening method thereof, and applications thereof |
CN111321178B (zh) * | 2020-03-02 | 2023-07-28 | 宁波酶赛生物工程有限公司 | 一种l-2-氨基丁酰胺的制备方法 |
KR102363913B1 (ko) * | 2020-06-26 | 2022-02-18 | 씨제이제일제당 (주) | L-쓰레오닌 디하이드라타아제의 신규 변이체 및 이를 이용한 l-이소류신 생산 방법 |
CN114540335A (zh) * | 2020-11-25 | 2022-05-27 | 湖南引航生物科技有限公司 | 固定化经修饰的苏氨酸转醛酶及其应用 |
CN113430219B (zh) * | 2021-06-25 | 2022-06-07 | 新泰市佳禾生物科技有限公司 | 水稻色氨酸脱羧酶及其生产方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0245497A4 (en) * | 1985-11-12 | 1989-06-27 | American Biogenetics Corp | BIOGENETIC CASSETTE. |
DE3942947A1 (de) * | 1989-12-23 | 1991-06-27 | Forschungszentrum Juelich Gmbh | Verfahren zur herstellung von l-isoleucin und dafuer geeignete mikroorganismen und rekombinante dna |
-
1994
- 1994-01-14 DE DE4400926A patent/DE4400926C1/de not_active Expired - Fee Related
-
1995
- 1995-01-09 EP EP95905043A patent/EP0739417B1/de not_active Expired - Lifetime
- 1995-01-09 DE DE59510787T patent/DE59510787D1/de not_active Expired - Lifetime
- 1995-01-09 DK DK95905043T patent/DK0739417T3/da active
- 1995-01-09 AT AT95905043T patent/ATE248921T1/de not_active IP Right Cessation
- 1995-01-09 JP JP51876495A patent/JP4471402B2/ja active Active
- 1995-01-09 WO PCT/DE1995/000017 patent/WO1995019442A1/de active IP Right Grant
- 1995-01-09 ES ES95905043T patent/ES2206488T3/es not_active Expired - Lifetime
- 1995-01-09 PT PT95905043T patent/PT739417E/pt unknown
- 1995-01-09 US US08/669,378 patent/US6107063A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DK0739417T3 (da) | 2004-01-05 |
JPH09508011A (ja) | 1997-08-19 |
EP0739417A1 (de) | 1996-10-30 |
EP0739417B1 (de) | 2003-09-03 |
US6107063A (en) | 2000-08-22 |
DE4400926C1 (de) | 1995-06-01 |
JP4471402B2 (ja) | 2010-06-02 |
WO1995019442A1 (de) | 1995-07-20 |
ATE248921T1 (de) | 2003-09-15 |
ES2206488T3 (es) | 2004-05-16 |
DE59510787D1 (de) | 2003-10-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT739417E (pt) | Producao de l-isoleucina atraves de microrganismos recombinantes com treonina desidratase desregulada | |
NO970049L (no) | Nukleinsyre holdt i preparat, dets fremstilling og anvendelse | |
ZA200004560B (en) | New nucleotide sequences coding for the thrE gene and process for the enzymatic production of L-threonine using coryneform bacteria. | |
BR0014115A (pt) | Métodos de produzir um panto-composto, pantotenato e beta-alanina, de aumentar a produção de um panto-composto e de edentificar compostos que modulam a atividade da pantotenato cinase, microorganismo recombinante, vetor, molécula de ácido nuleico isolada, polipetìdeo e proteìna da pantotenato cinase isolada | |
ATE422548T1 (de) | L-lysin produzierende coryneforme bakterien und verfahren zur herstellung von l-lysin | |
MX9701025A (es) | Genes de penicilina g acilasa mutados. | |
ID24149A (id) | PROSES FERMENTASI UNTUK PEMBUATAN ASAM D-PANTOTENIK DENGAN MENGUATKAN GEN panD PADA MIKROORGANISME | |
BR9508022A (pt) | Bactéria corineforme produtora de ácido l-glutâmico, processo para produzir ácido l-glutâmico, gene codificando para uma enzima, dna recombinante, bactéria corineforme, e, processo para produzir l-lisina | |
DE69534618D1 (de) | Verfahren zur herstellung rekombinanter adeno-associated viren (aav) und deren verwendung | |
PL376381A1 (en) | Methods and media for controlling sialylation of proteins produced by mammalian cells | |
MY127754A (en) | Plasmid autonomously replicable in coryneform bacteria. | |
ATE239036T1 (de) | Rekombinantes core-streptavidin | |
NZ512835A (en) | Genes identified as required for proliferation in escherichia coli | |
DK0851926T3 (da) | Varianter af humant rekombinant gamminterferon (rhu-IFN-gamma) med forøget termisk stabilitet | |
HK1021983A1 (en) | Protein participating in activation of nitrile hy dratase and gene encoding the same | |
HUP0001176A2 (hu) | Eljárás L-aminosavak fermentációs úton történő előállítására korineform baktériumok alkalmazásával | |
NZ525635A (en) | Expression vectors with modified ColE1 origin of replication to increase the yield of plasmid DNA in the plasmid production process in bacterial host cells | |
SE9401380D0 (sv) | Ny celltillväxt-relaterad peptid och användning därav | |
ES2170107T3 (es) | Nueva cefalosporina c-acilasa. | |
ZA200002658B (en) | Process for the preparation of L-amino acids by fermentation and nucleotide sequences coding for the accDA gene. | |
EP1047710B1 (de) | Orotidin-5'-phosphatdecarboxylase-gen, genkonstrukt enthaltend dieses gen und seine verwendung | |
ATE423205T1 (de) | Verfahren zur biologischen herstellung von l- pipekolinsäure | |
ZA961676B (en) | Process for preparing optically active amines | |
RU2002128638A (ru) | Способ производства l-аминокислот посредством ферментации | |
DE69231145D1 (de) | Für eine Esterase kodierendes Gen und dieses Gen enthaltender Mikroorganismus |