PT3660073T - Poli-(lactídeo-co-glicolídeo) de libertação imediata reduzida - Google Patents

Poli-(lactídeo-co-glicolídeo) de libertação imediata reduzida

Info

Publication number: PT3660073T
Authority: PT; Portugal
Prior art keywords: polymers; methods; low; burst; produce
Prior art date: 2007-02-15

Application number

PT192030716T

Other languages

English (en)

Original Assignee

Tolmar International Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-02-15

Filing date

2008-02-13

Publication date

2023-08-31

2008-02-13 Application filed by Tolmar International Ltd filed Critical Tolmar International Ltd

2023-08-31 Publication of PT3660073T publication Critical patent/PT3660073T/pt

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
- C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
- C08G63/08—Lactones or lactides
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/88—Post-polymerisation treatment
- C08G63/90—Purification; Drying
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Immunology (AREA)
Polymers & Plastics (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Reproductive Health (AREA)
Gastroenterology & Hepatology (AREA)
Oncology (AREA)
Ophthalmology & Optometry (AREA)
Communicable Diseases (AREA)
Pain & Pain Management (AREA)
Inorganic Chemistry (AREA)
Dermatology (AREA)
Gynecology & Obstetrics (AREA)
Rheumatology (AREA)
Neurology (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Psychiatry (AREA)
Physical Education & Sports Medicine (AREA)
Virology (AREA)
Tropical Medicine & Parasitology (AREA)
Pregnancy & Childbirth (AREA)

PT192030716T 2007-02-15 2008-02-13 Poli-(lactídeo-co-glicolídeo) de libertação imediata reduzida PT3660073T (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US90143507P	2007-02-15	2007-02-15

Publications (1)

Publication Number	Publication Date
PT3660073T true PT3660073T (pt)	2023-08-31

Family

ID=39504385

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
PT192030716T PT3660073T (pt)	2007-02-15	2008-02-13	Poli-(lactídeo-co-glicolídeo) de libertação imediata reduzida
PT151852183T PT3202814T (pt)	2007-02-15	2008-02-13	Poli-(lactido/glicolido) de libertação imediata reduzida e métodos de produção de polímeros
PT87255113T PT2115029E (pt)	2007-02-15	2008-02-13	Poli-(lactido/glicolido) de efeito de libertação imediata reduzido e métodos de produção de polímeros

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
PT151852183T PT3202814T (pt)	2007-02-15	2008-02-13	Poli-(lactido/glicolido) de libertação imediata reduzida e métodos de produção de polímeros
PT87255113T PT2115029E (pt)	2007-02-15	2008-02-13	Poli-(lactido/glicolido) de efeito de libertação imediata reduzido e métodos de produção de polímeros

Country Status (16)

Country	Link
US (7)	US9187593B2 (pt)
EP (3)	EP3660073B1 (pt)
JP (3)	JP5342459B2 (pt)
CA (1)	CA2678350C (pt)
CY (2)	CY1116785T1 (pt)
DK (3)	DK3202814T3 (pt)
ES (3)	ES2755374T3 (pt)
FI (1)	FI3660073T3 (pt)
HK (1)	HK1138303A1 (pt)
HR (3)	HRP20231117T3 (pt)
HU (3)	HUE047775T2 (pt)
LT (2)	LT3202814T (pt)
PL (3)	PL3660073T3 (pt)
PT (3)	PT3660073T (pt)
SI (3)	SI2115029T1 (pt)
WO (1)	WO2008100532A1 (pt)

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US8852638B2 (en)	2005-09-30	2014-10-07	Durect Corporation	Sustained release small molecule drug formulation
WO2007084460A2 (en)	2006-01-18	2007-07-26	Qps, Llc	Pharmaceutical compositions with enhanced stability
CA2678350C (en)	2007-02-15	2015-11-17	Qlt Usa, Inc.	Low-burst poly(lactide-glycolide)
ES2562878T3 (es)	2007-05-25	2016-03-08	Indivior Uk Limited	Formulaciones de liberación sostenida de compuestos de risperidona
WO2009148580A2 (en) *	2008-06-03	2009-12-10	Qlt Usa, Inc.	Controlled release copolymer formulation with improved release kinetics
US10350159B2 (en)	2010-05-31	2019-07-16	Laboratories Farmacéuticos Rovi, S.A.	Paliperidone implant formulation
US10335366B2 (en)	2010-05-31	2019-07-02	Laboratorios Farmacéuticos Rovi, S.A.	Risperidone or paliperidone implant formulation
US10285936B2 (en)	2010-05-31	2019-05-14	Laboratorios Farmacéuticos Rovi, S.A.	Injectable composition with aromatase inhibitor
HUE057236T2 (hu)	2010-05-31	2022-04-28	Farm Rovi Lab Sa	Készítmények befecskendezhetõ in-situ biológiailag lebontható implantátumokhoz
US10463607B2 (en)	2010-05-31	2019-11-05	Laboratorios Farmaceutics Rofi S.A.	Antipsychotic Injectable Depot Composition
US10881605B2 (en)	2010-05-31	2021-01-05	Laboratorios Farmaceuticos Rovi, S.A.	Methods for the preparation of injectable depot compositions
ES2589106T3 (es)	2010-05-31	2016-11-10	Laboratorios Farmaceuticos Rovi, S.A.	Composición inyectable antipsicótica de liberación controlada
US9272044B2 (en)	2010-06-08	2016-03-01	Indivior Uk Limited	Injectable flowable composition buprenorphine
GB2481018B (en)	2010-06-08	2015-03-18	Rb Pharmaceuticals Ltd	Injectable flowable composition comprising buprenorphine
GB2481017B (en)	2010-06-08	2015-01-07	Rb Pharmaceuticals Ltd	Microparticle buprenorphine suspension
CN103421172B (zh) *	2012-05-23	2016-01-20	上海现代药物制剂工程研究中心有限公司	一种生物可降解聚酯的纯化工艺
AU2014249008B2 (en)	2013-03-11	2018-12-06	Durect Corporation	Injectable controlled release composition comprising high viscosity liquid carrier
US20140308352A1 (en)	2013-03-11	2014-10-16	Zogenix Inc.	Compositions and methods involving polymer, solvent, and high viscosity liquid carrier material
US10011681B2 (en)	2013-04-11	2018-07-03	Mitsui Chemicals, Inc.	Process for producing a lactic acid-glycolic acid copolymer or a salt thereof
MX2016007345A (es) *	2013-12-06	2016-12-09	Envisia Therapeutics Inc	Implante intracameral para el tratamiento de una condicion ocular.
GB201404139D0 (en)	2014-03-10	2014-04-23	Rb Pharmaceuticals Ltd	Sustained release buprenorphine solution formulations
US20160106804A1 (en) *	2014-10-15	2016-04-21	Yuhua Li	Pharmaceutical composition with improved stability
US11000520B2 (en)	2014-11-07	2021-05-11	Indivior Uk Limited	Buprenorphine dosing regimens
US11458041B2 (en)	2015-10-08	2022-10-04	Ocular Therapeutix, Inc.	Punctal plug and bioadhesives
US10646484B2 (en)	2017-06-16	2020-05-12	Indivior Uk Limited	Methods to treat opioid use disorder
CN112545995B (zh) *	2018-05-16	2024-02-23	珠海市丽珠微球科技有限公司	一种阿立哌唑缓释微球及其制备方法
US20210251893A1 (en)	2020-02-06	2021-08-19	Ocular Therapeutix, Inc.	Compositions and Methods for Treating Ocular Diseases
EP4221684A1 (en)	2020-09-30	2023-08-09	Tolmar International Limited	Biodegradable polymer delivery system for extended delivery of testosterone

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2008
- 2008-02-13 CA CA2678350A patent/CA2678350C/en not_active Expired - Fee Related
- 2008-02-13 SI SI200831512T patent/SI2115029T1/sl unknown
- 2008-02-13 PL PL19203071.6T patent/PL3660073T3/pl unknown
- 2008-02-13 LT LT15185218T patent/LT3202814T/lt unknown
- 2008-02-13 HU HUE15185218A patent/HUE047775T2/hu unknown
- 2008-02-13 SI SI200832098T patent/SI3202814T1/sl unknown
- 2008-02-13 DK DK15185218T patent/DK3202814T3/da active
- 2008-02-13 DK DK08725511.3T patent/DK2115029T3/en active
- 2008-02-13 EP EP19203071.6A patent/EP3660073B1/en active Active
- 2008-02-13 ES ES15185218T patent/ES2755374T3/es active Active
- 2008-02-13 DK DK19203071.6T patent/DK3660073T3/da active
- 2008-02-13 ES ES19203071T patent/ES2956244T3/es active Active
- 2008-02-13 FI FIEP19203071.6T patent/FI3660073T3/fi active
- 2008-02-13 HR HRP20231117TT patent/HRP20231117T3/hr unknown
- 2008-02-13 PT PT192030716T patent/PT3660073T/pt unknown
- 2008-02-13 PT PT151852183T patent/PT3202814T/pt unknown
- 2008-02-13 US US12/527,377 patent/US9187593B2/en not_active Expired - Fee Related
- 2008-02-13 WO PCT/US2008/001887 patent/WO2008100532A1/en active Application Filing
- 2008-02-13 JP JP2009550095A patent/JP5342459B2/ja active Active
- 2008-02-13 EP EP15185218.3A patent/EP3202814B1/en active Active
- 2008-02-13 LT LTEP19203071.6T patent/LT3660073T/lt unknown
- 2008-02-13 PL PL08725511T patent/PL2115029T3/pl unknown
- 2008-02-13 EP EP08725511.3A patent/EP2115029B1/en active Active
- 2008-02-13 HU HUE19203071A patent/HUE063170T2/hu unknown
- 2008-02-13 PT PT87255113T patent/PT2115029E/pt unknown
- 2008-02-13 PL PL15185218T patent/PL3202814T3/pl unknown
- 2008-02-13 HU HUE08725511A patent/HUE025842T2/en unknown
- 2008-02-13 ES ES08725511.3T patent/ES2550014T3/es active Active
- 2008-02-13 SI SI200832213T patent/SI3660073T1/sl unknown
2010
- 2010-05-10 HK HK10104526.3A patent/HK1138303A1/xx unknown
2013
- 2013-08-09 JP JP2013166807A patent/JP5848290B2/ja active Active
2015
- 2015-04-10 JP JP2015080726A patent/JP6195587B2/ja active Active
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Publication number	Publication date
SI2115029T1 (sl)	2016-01-29
CA2678350C (en)	2015-11-17
US20220202941A1 (en)	2022-06-30
US9187593B2 (en)	2015-11-17
HRP20150997T1 (hr)	2015-12-18
ES2550014T3 (es)	2015-11-03
DK3202814T3 (da)	2019-11-25
JP6195587B2 (ja)	2017-09-13
ES2956244T3 (es)	2023-12-15
EP3660073B1 (en)	2023-07-12
US20190209643A1 (en)	2019-07-11
DK3660073T3 (da)	2023-09-18
LT3202814T (lt)	2019-12-10
JP2013224339A (ja)	2013-10-31
US10206970B2 (en)	2019-02-19
LT3660073T (lt)	2023-10-10
JP2015127351A (ja)	2015-07-09
US11147880B2 (en)	2021-10-19
HK1138303A1 (en)	2010-08-20
FI3660073T3 (fi)	2023-09-11
PT3202814T (pt)	2019-11-26
DK2115029T3 (en)	2015-10-05
HRP20192055T1 (hr)	2020-02-21
SI3660073T1 (sl)	2023-10-30
US11717572B2 (en)	2023-08-08
HUE063170T2 (hu)	2024-01-28
US9561282B2 (en)	2017-02-07
US20100292195A1 (en)	2010-11-18
HUE047775T2 (hu)	2020-05-28
EP2115029B1 (en)	2015-09-16
CY1116785T1 (el)	2017-03-15
CA2678350A1 (en)	2008-08-21
US20160106847A1 (en)	2016-04-21
JP5848290B2 (ja)	2016-01-27
US20170216395A1 (en)	2017-08-03
US9655970B2 (en)	2017-05-23
EP3202814A1 (en)	2017-08-09
HUE025842T2 (en)	2016-04-28
PL3202814T3 (pl)	2020-01-31
JP5342459B2 (ja)	2013-11-13
JP2010519218A (ja)	2010-06-03
ES2755374T3 (es)	2020-04-22
EP3202814B1 (en)	2019-10-16
PT2115029E (pt)	2015-10-26
WO2008100532A1 (en)	2008-08-21
PL2115029T3 (pl)	2016-01-29
PL3660073T3 (pl)	2023-12-27
SI3202814T1 (sl)	2019-12-31
US9974824B2 (en)	2018-05-22
US20170095560A1 (en)	2017-04-06
EP3660073A1 (en)	2020-06-03
CY1122304T1 (el)	2021-01-27
HRP20231117T3 (hr)	2023-12-22
US20180311305A1 (en)	2018-11-01
EP2115029A1 (en)	2009-11-11

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