HK1138303A1 - Low burst poly-(lactide/glycolide) and methods to produce polymers -(/) - Google Patents

Low burst poly-(lactide/glycolide) and methods to produce polymers -(/)

Info

Publication number: HK1138303A1
Authority: HK; Hong Kong
Prior art keywords: glycolide; lactide; poly; methods; produce polymers
Prior art date: 2007-02-15

Application number

HK10104526.3A

Other languages

English (en)

Chinese (zh)

Inventor

Eric Dadey

John Middleton

Richard L Norton

Original Assignee

Tolmar Therapeutics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-02-15

Filing date

2010-05-10

Publication date

2010-08-20

2010-05-10 Application filed by Tolmar Therapeutics Inc filed Critical Tolmar Therapeutics Inc

2010-08-20 Publication of HK1138303A1 publication Critical patent/HK1138303A1/xx

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
- C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
- C08G63/08—Lactones or lactides
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/88—Post-polymerisation treatment
- C08G63/90—Purification; Drying

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Immunology (AREA)
Polymers & Plastics (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Reproductive Health (AREA)
Gastroenterology & Hepatology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pain & Pain Management (AREA)
Ophthalmology & Optometry (AREA)
Inorganic Chemistry (AREA)
Dermatology (AREA)
Rheumatology (AREA)
Gynecology & Obstetrics (AREA)
Neurology (AREA)
Diabetes (AREA)
Virology (AREA)
Psychiatry (AREA)
Urology & Nephrology (AREA)
Tropical Medicine & Parasitology (AREA)
Physical Education & Sports Medicine (AREA)
Pregnancy & Childbirth (AREA)

HK10104526.3A 2007-02-15 2010-05-10 Low burst poly-(lactide/glycolide) and methods to produce polymers -(/) HK1138303A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US90143507P	2007-02-15	2007-02-15
PCT/US2008/001887 WO2008100532A1 (en)	2007-02-15	2008-02-13	Low burst poly-(lactide/glycolide) and methods to produce polymers

Publications (1)

Publication Number	Publication Date
HK1138303A1 true HK1138303A1 (en)	2010-08-20

Family

ID=39504385

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK10104526.3A HK1138303A1 (en)	2007-02-15	2010-05-10	Low burst poly-(lactide/glycolide) and methods to produce polymers -(/)

Country Status (16)

Country	Link
US (7)	US9187593B2 (xx)
EP (3)	EP3202814B1 (xx)
JP (3)	JP5342459B2 (xx)
CA (1)	CA2678350C (xx)
CY (2)	CY1116785T1 (xx)
DK (3)	DK3202814T3 (xx)
ES (3)	ES2550014T3 (xx)
FI (1)	FI3660073T3 (xx)
HK (1)	HK1138303A1 (xx)
HR (3)	HRP20231117T3 (xx)
HU (3)	HUE047775T2 (xx)
LT (2)	LT3660073T (xx)
PL (3)	PL3660073T3 (xx)
PT (3)	PT3660073T (xx)
SI (3)	SI3660073T1 (xx)
WO (1)	WO2008100532A1 (xx)

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MX354603B (es)	2007-05-25	2018-03-13	Indivior Uk Ltd	Formulaciones de transferencia sostenida de compuestos de risperidona.
AU2009255675B2 (en) *	2008-06-03	2014-10-09	Tolmar Therapeutics, Inc.	Controlled release copolymer formulation with improved release kinetics
US10285936B2 (en)	2010-05-31	2019-05-14	Laboratorios Farmacéuticos Rovi, S.A.	Injectable composition with aromatase inhibitor
US10335366B2 (en)	2010-05-31	2019-07-02	Laboratorios Farmacéuticos Rovi, S.A.	Risperidone or paliperidone implant formulation
US10350159B2 (en)	2010-05-31	2019-07-16	Laboratories Farmacéuticos Rovi, S.A.	Paliperidone implant formulation
US10881605B2 (en)	2010-05-31	2021-01-05	Laboratorios Farmaceuticos Rovi, S.A.	Methods for the preparation of injectable depot compositions
LT2394664T (lt)	2010-05-31	2016-09-26	Laboratorios Farmaceuticos Rovi, S.A.	Antipsichozinė injekcinė depozitinė kompozicija
HRP20211853T1 (hr)	2010-05-31	2022-03-04	Laboratorios Farmaceuticos Rovi, S.A.	Sastavi in situ injekcijskih biorazgradivih implantata
US10463607B2 (en)	2010-05-31	2019-11-05	Laboratorios Farmaceutics Rofi S.A.	Antipsychotic Injectable Depot Composition
GB2513267B (en)	2010-06-08	2015-03-18	Rb Pharmaceuticals Ltd	Injectable flowable composition comprising buprenorphine
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CN112545995B (zh) *	2018-05-16	2024-02-23	珠海市丽珠微球科技有限公司	一种阿立哌唑缓释微球及其制备方法
DK3861985T3 (da)	2020-02-06	2023-07-24	Ocular Therapeutix Inc	Sammensætninger og fremgangsmåder til behandling af øjensygdomme
CA3197318A1 (en)	2020-09-30	2022-04-07	Tolmar International Limited	Biodegradable polymer delivery system for extended delivery of testosterone
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JP5188670B2 (ja) *	2001-06-29	2013-04-24	武田薬品工業株式会社	徐放性組成物およびその製造法
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PL1824460T3 (pl) *	2004-11-10	2015-09-30	Tolmar Therapeutics Inc	Stabilizowany polimerowy układ dostarczania
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PL3660073T3 (pl)	2007-02-15	2023-12-27	Tolmar International Limited	Poli(laktyd-ko-glikolid) o niskim nagłym uwalnianiu

2008
- 2008-02-13 PL PL19203071.6T patent/PL3660073T3/pl unknown
- 2008-02-13 EP EP15185218.3A patent/EP3202814B1/en active Active
- 2008-02-13 FI FIEP19203071.6T patent/FI3660073T3/fi active
- 2008-02-13 SI SI200832213T patent/SI3660073T1/sl unknown
- 2008-02-13 HU HUE15185218A patent/HUE047775T2/hu unknown
- 2008-02-13 ES ES08725511.3T patent/ES2550014T3/es active Active
- 2008-02-13 DK DK15185218T patent/DK3202814T3/da active
- 2008-02-13 JP JP2009550095A patent/JP5342459B2/ja active Active
- 2008-02-13 HU HUE08725511A patent/HUE025842T2/en unknown
- 2008-02-13 LT LTEP19203071.6T patent/LT3660073T/lt unknown
- 2008-02-13 EP EP08725511.3A patent/EP2115029B1/en active Active
- 2008-02-13 SI SI200832098T patent/SI3202814T1/sl unknown
- 2008-02-13 PT PT192030716T patent/PT3660073T/pt unknown
- 2008-02-13 PT PT151852183T patent/PT3202814T/pt unknown
- 2008-02-13 DK DK08725511.3T patent/DK2115029T3/en active
- 2008-02-13 SI SI200831512T patent/SI2115029T1/sl unknown
- 2008-02-13 CA CA2678350A patent/CA2678350C/en not_active Expired - Fee Related
- 2008-02-13 ES ES19203071T patent/ES2956244T3/es active Active
- 2008-02-13 PL PL08725511T patent/PL2115029T3/pl unknown
- 2008-02-13 HU HUE19203071A patent/HUE063170T2/hu unknown
- 2008-02-13 PT PT87255113T patent/PT2115029E/pt unknown
- 2008-02-13 PL PL15185218T patent/PL3202814T3/pl unknown
- 2008-02-13 US US12/527,377 patent/US9187593B2/en not_active Expired - Fee Related
- 2008-02-13 LT LT15185218T patent/LT3202814T/lt unknown
- 2008-02-13 HR HRP20231117TT patent/HRP20231117T3/hr unknown
- 2008-02-13 WO PCT/US2008/001887 patent/WO2008100532A1/en active Application Filing
- 2008-02-13 EP EP19203071.6A patent/EP3660073B1/en active Active
- 2008-02-13 DK DK19203071.6T patent/DK3660073T3/da active
- 2008-02-13 ES ES15185218T patent/ES2755374T3/es active Active
2010
- 2010-05-10 HK HK10104526.3A patent/HK1138303A1/xx unknown
2013
- 2013-08-09 JP JP2013166807A patent/JP5848290B2/ja active Active
2015
- 2015-04-10 JP JP2015080726A patent/JP6195587B2/ja active Active
- 2015-09-21 HR HRP20150997TT patent/HRP20150997T1/hr unknown
- 2015-10-08 CY CY20151100906T patent/CY1116785T1/el unknown
- 2015-10-27 US US14/924,243 patent/US9561282B2/en active Active
2016
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ES2755374T3 (es)	2020-04-22
US20100292195A1 (en)	2010-11-18
EP3202814A1 (en)	2017-08-09
PT3660073T (pt)	2023-08-31
US10206970B2 (en)	2019-02-19
LT3660073T (lt)	2023-10-10
PT3202814T (pt)	2019-11-26
HUE025842T2 (en)	2016-04-28
WO2008100532A1 (en)	2008-08-21
CY1122304T1 (el)	2021-01-27
JP2010519218A (ja)	2010-06-03
JP6195587B2 (ja)	2017-09-13
EP2115029B1 (en)	2015-09-16
US9561282B2 (en)	2017-02-07
CA2678350C (en)	2015-11-17
JP2013224339A (ja)	2013-10-31
ES2550014T3 (es)	2015-11-03
US20170216395A1 (en)	2017-08-03
ES2956244T3 (es)	2023-12-15
PL3202814T3 (pl)	2020-01-31
US20160106847A1 (en)	2016-04-21
US11147880B2 (en)	2021-10-19
HUE063170T2 (hu)	2024-01-28
EP3660073B1 (en)	2023-07-12
CA2678350A1 (en)	2008-08-21
US9187593B2 (en)	2015-11-17
EP3202814B1 (en)	2019-10-16
DK3202814T3 (da)	2019-11-25
FI3660073T3 (fi)	2023-09-11
US20180311305A1 (en)	2018-11-01
US20190209643A1 (en)	2019-07-11
SI3202814T1 (sl)	2019-12-31
US20170095560A1 (en)	2017-04-06
SI2115029T1 (sl)	2016-01-29
EP3660073A1 (en)	2020-06-03
JP2015127351A (ja)	2015-07-09
US9655970B2 (en)	2017-05-23
PL2115029T3 (pl)	2016-01-29
HRP20192055T1 (hr)	2020-02-21
HUE047775T2 (hu)	2020-05-28
DK2115029T3 (en)	2015-10-05
HRP20150997T1 (hr)	2015-12-18
EP2115029A1 (en)	2009-11-11
PL3660073T3 (pl)	2023-12-27
JP5848290B2 (ja)	2016-01-27
PT2115029E (pt)	2015-10-26
US20220202941A1 (en)	2022-06-30
HRP20231117T3 (hr)	2023-12-22
JP5342459B2 (ja)	2013-11-13
CY1116785T1 (el)	2017-03-15
US9974824B2 (en)	2018-05-22
US11717572B2 (en)	2023-08-08
DK3660073T3 (da)	2023-09-18
LT3202814T (lt)	2019-12-10
SI3660073T1 (sl)	2023-10-30

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