PT2947086T - Novo composto de pirimidina fundida ou sal do mesmo - Google Patents

Novo composto de pirimidina fundida ou sal do mesmo

Info

Publication number
PT2947086T
PT2947086T PT148367824T PT14836782T PT2947086T PT 2947086 T PT2947086 T PT 2947086T PT 148367824 T PT148367824 T PT 148367824T PT 14836782 T PT14836782 T PT 14836782T PT 2947086 T PT2947086 T PT 2947086T
Authority
PT
Portugal
Prior art keywords
salt
pyrimidine compound
fused pyrimidine
novel fused
novel
Prior art date
Application number
PT148367824T
Other languages
English (en)
Inventor
Iguchi Satoru
Hosoi Fumihito
Sagara Takeshi
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Publication of PT2947086T publication Critical patent/PT2947086T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
PT148367824T 2013-08-12 2014-08-11 Novo composto de pirimidina fundida ou sal do mesmo PT2947086T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2013167600 2013-08-12

Publications (1)

Publication Number Publication Date
PT2947086T true PT2947086T (pt) 2018-03-09

Family

ID=52468312

Family Applications (1)

Application Number Title Priority Date Filing Date
PT148367824T PT2947086T (pt) 2013-08-12 2014-08-11 Novo composto de pirimidina fundida ou sal do mesmo

Country Status (23)

Country Link
US (1) US9580432B2 (pt)
EP (1) EP2947086B1 (pt)
JP (1) JP6035423B2 (pt)
KR (1) KR101828187B1 (pt)
CN (1) CN105452257B (pt)
AU (1) AU2014307437B2 (pt)
BR (1) BR112016002069B1 (pt)
CA (1) CA2921208C (pt)
DK (1) DK2947086T3 (pt)
ES (1) ES2661733T3 (pt)
HK (1) HK1217703A1 (pt)
HU (1) HUE036834T2 (pt)
MX (1) MX360498B (pt)
MY (1) MY171831A (pt)
NO (1) NO2947086T3 (pt)
PH (1) PH12015502737A1 (pt)
PL (1) PL2947086T3 (pt)
PT (1) PT2947086T (pt)
RU (1) RU2666349C2 (pt)
SG (1) SG11201600048VA (pt)
TR (1) TR201802875T4 (pt)
TW (1) TWI585089B (pt)
WO (1) WO2015022926A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2921410C (en) 2013-08-23 2023-03-28 Neupharma, Inc. Quinazoline derivatives, compositions and their use as kinase inhibitors
CA2974335C (en) * 2015-01-30 2019-04-09 Taiho Pharmaceutical Co., Ltd. Novel salt of fused pyrimidine compound and crystal thereof
TWI638817B (zh) * 2015-01-30 2018-10-21 大鵬藥品工業股份有限公司 免疫疾病之預防及／或治療劑
CA2997051C (en) 2015-09-01 2020-03-24 Taiho Pharmaceutical Co., Ltd. Novel pyrazolo[3,4-d]pyrimidine compound or salt thereof
MA41559A (fr) * 2015-09-08 2017-12-26 Taiho Pharmaceutical Co Ltd Composé de pyrimidine condensé ou un sel de celui-ci
US9834561B2 (en) * 2015-10-28 2017-12-05 Scinopharm Taiwan, Ltd. Process for preparing ibrutinib and its intermediates
EP3269370B1 (en) 2016-02-23 2020-01-08 Taiho Pharmaceutical Co., Ltd. Novel condensed pyrimidine compound or salt thereof
JP7101165B2 (ja) * 2016-08-15 2022-07-14 ニューファーマ， インコーポレイテッド 特定の化学的実体、組成物、および方法
JP7223684B2 (ja) * 2017-02-28 2023-02-16 大鵬薬品工業株式会社 ピラゾロ［３，４－ｄ］ピリミジン化合物を用いた抗腫瘍効果増強剤
WO2020188015A1 (en) 2019-03-21 2020-09-24 Onxeo A dbait molecule in combination with kinase inhibitor for the treatment of cancer
AU2020378630A1 (en) 2019-11-08 2022-05-26 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for the treatment of cancers that have acquired resistance to kinase inhibitors
TW202135817A (zh) * 2019-12-19 2021-10-01 日商大鵬藥品工業股份有限公司 以縮合嘧啶化合物作為有效成分之治療劑
WO2021148581A1 (en) 2020-01-22 2021-07-29 Onxeo Novel dbait molecule and its use
EP4183395A1 (en) * 2020-07-15 2023-05-24 Taiho Pharmaceutical Co., Ltd. Pyrimidine compound-containing combination to be used in tumor treatment
WO2022140246A1 (en) 2020-12-21 2022-06-30 Hangzhou Jijing Pharmaceutical Technology Limited Methods and compounds for targeted autophagy
CN114736207B (zh) * 2022-04-28 2023-03-31 武汉九州钰民医药科技有限公司 一种小分子her2抑制剂的制备工艺

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7157434B2 (en) 2003-10-27 2007-01-02 Genelabs Technologies, Inc. Nucleoside compounds for treating viral infections
EP1968979A2 (en) 2005-12-08 2008-09-17 Abbott Laboratories 9-membered heterobicyclic compounds as inhibitors of protein kinases
EP2007373A4 (en) 2006-03-29 2012-12-19 Foldrx Pharmaceuticals Inc INHIBITION OF ALPHA SYNUCLEINE TOXICITY
ES2403546T3 (es) 2006-11-03 2013-05-20 Pharmacyclics, Inc. Sonda de actividad de la tirosina-cinasa de Bruton y procedimiento de utilización
CA3143428A1 (en) * 2007-03-28 2008-10-09 Pharmacyclics Llc 8-amino-3-substituted-imidazo[1,5-a]pyrazine and use thereof as inhibitors of bruton's tyrosine kinase
WO2009057733A1 (ja) * 2007-10-31 2009-05-07 Santen Pharmaceutical Co., Ltd. 血管新生阻害活性を有する新規インドール誘導体
KR20110025224A (ko) 2008-06-27 2011-03-09 아빌라 테라퓨틱스, 인크. 헤테로아릴 화합물 및 이의 용도
US8338439B2 (en) 2008-06-27 2012-12-25 Celgene Avilomics Research, Inc. 2,4-disubstituted pyrimidines useful as kinase inhibitors
WO2013010136A2 (en) 2011-07-13 2013-01-17 Pharmacyclics, Inc. Inhibitors of bruton's tyrosine kinase
WO2013010889A1 (en) * 2011-07-15 2013-01-24 Sanofi-Aventis Deutschland Gmbh A drug delivery device
WO2013108809A1 (ja) 2012-01-19 2013-07-25 大鵬薬品工業株式会社 ３，５－二置換ベンゼンアルキニル化合物及びその塩
CN104250250A (zh) * 2013-06-25 2014-12-31 苏州科捷生物医药有限公司 4-芳香胺基嘧啶类化合物及其抗肿瘤用途

Also Published As

Publication number Publication date
CA2921208A1 (en) 2015-02-19
EP2947086A4 (en) 2016-06-22
EP2947086B1 (en) 2018-01-03
KR20160038891A (ko) 2016-04-07
HUE036834T2 (hu) 2018-08-28
TR201802875T4 (tr) 2018-03-21
HK1217703A1 (zh) 2017-01-20
US9580432B2 (en) 2017-02-28
CA2921208C (en) 2018-02-20
PL2947086T3 (pl) 2018-06-29
JP6035423B2 (ja) 2016-11-30
RU2666349C2 (ru) 2018-09-07
SG11201600048VA (en) 2016-03-30
JPWO2015022926A1 (ja) 2017-03-02
TW201536786A (zh) 2015-10-01
AU2014307437A1 (en) 2016-01-21
RU2015156524A (ru) 2017-09-14
ES2661733T3 (es) 2018-04-03
EP2947086A1 (en) 2015-11-25
AU2014307437B2 (en) 2016-12-15
TWI585089B (zh) 2017-06-01
MX2016001845A (es) 2016-05-16
CN105452257B (zh) 2017-09-05
DK2947086T3 (en) 2018-03-19
CN105452257A (zh) 2016-03-30
MY171831A (en) 2019-11-01
PH12015502737B1 (en) 2016-03-07
NO2947086T3 (pt) 2018-06-02
MX360498B (es) 2018-11-05
WO2015022926A1 (ja) 2015-02-19
US20160115168A1 (en) 2016-04-28
BR112016002069B1 (pt) 2020-08-18
BR112016002069A2 (pt) 2017-08-01
KR101828187B1 (ko) 2018-02-09
PH12015502737A1 (en) 2016-03-07

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