PT2513085T - Compostos bicíclicos como ligantes do recetor da acetilcolina nicotínico alfa4beta2 - Google Patents

Compostos bicíclicos como ligantes do recetor da acetilcolina nicotínico alfa4beta2

Info

Publication number
PT2513085T
PT2513085T PT98186489T PT09818648T PT2513085T PT 2513085 T PT2513085 T PT 2513085T PT 98186489 T PT98186489 T PT 98186489T PT 09818648 T PT09818648 T PT 09818648T PT 2513085 T PT2513085 T PT 2513085T
Authority
PT
Portugal
Prior art keywords
acetylcholine receptor
receptor ligands
nicotinic acetylcholine
bicyclic compounds
bicyclic
Prior art date
Application number
PT98186489T
Other languages
English (en)
Inventor
Rasheed Mohammed Abdul
Rao Ravella Srinivasa
Jayarajan Pradeep
Bhyrapuneni Gopinadh
Ahmad Ishtiyaque
Nirogi Ramakrishna
Karbhari Shinde Anil
Jasti Venkateswarlu
Veeramalla Srinivas
Sastri Kambhampti Rama
Original Assignee
Suven Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suven Life Sciences Ltd filed Critical Suven Life Sciences Ltd
Publication of PT2513085T publication Critical patent/PT2513085T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
PT98186489T 2009-11-18 2009-12-31 Compostos bicíclicos como ligantes do recetor da acetilcolina nicotínico alfa4beta2 PT2513085T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN2838CH2009 2009-11-18

Publications (1)

Publication Number Publication Date
PT2513085T true PT2513085T (pt) 2016-11-14

Family

ID=42228992

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98186489T PT2513085T (pt) 2009-11-18 2009-12-31 Compostos bicíclicos como ligantes do recetor da acetilcolina nicotínico alfa4beta2

Country Status (24)

Country Link
US (1) US8735423B2 (pt)
EP (1) EP2513085B1 (pt)
JP (1) JP5536227B2 (pt)
KR (1) KR101376145B1 (pt)
CN (1) CN102741239B (pt)
CA (1) CA2773409C (pt)
CY (1) CY1118361T1 (pt)
DK (1) DK2513085T3 (pt)
EA (1) EA020506B1 (pt)
ES (1) ES2601905T3 (pt)
HK (1) HK1175782A1 (pt)
HR (1) HRP20161461T1 (pt)
HU (1) HUE033352T2 (pt)
IL (1) IL219637A (pt)
LT (1) LT2513085T (pt)
MX (1) MX2012005637A (pt)
NZ (1) NZ600536A (pt)
PL (1) PL2513085T3 (pt)
PT (1) PT2513085T (pt)
RS (1) RS55469B1 (pt)
SI (1) SI2513085T1 (pt)
SM (1) SMT201600444B (pt)
WO (1) WO2011061751A1 (pt)
ZA (1) ZA201203522B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA023553B1 (ru) * 2011-06-17 2016-06-30 Эли Лилли Энд Компани Агонисты рецептора mglu2
JP6103240B2 (ja) 2013-11-18 2017-03-29 トヨタ紡織株式会社 ピッチ材料の調整方法及び調整装置
EP3634408B1 (en) 2017-06-09 2022-12-28 Merck Sharp & Dohme LLC Azabicyclo[4.1.0]heptane allosteric modulators of the m4 muscarinic acetylcholine receptor
WO2023135528A1 (en) 2022-01-11 2023-07-20 Suven Life Sciences Limited Heteroalicyclic derivatives and their use in the treatment of cns disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4337341A (en) * 1976-11-02 1982-06-29 Eli Lilly And Company 4a-Aryl-octahydro-1H-2-pyrindines
FI95572C (fi) 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
AU7871498A (en) * 1996-12-20 1998-07-17 Novo Nordisk A/S A method of treating hypercholesterolemia and related disorders
EP1189612A4 (en) * 1999-06-30 2005-02-16 Daiichi Seiyaku Co VLA-4 INHIBITORY COMPOUNDS
WO2002089800A2 (en) 2001-05-05 2002-11-14 Smithkline Beecham P.L.C. N-aroyl cyclic amine derivatives as orexin receptor antagonists
FR2889187B1 (fr) * 2005-07-28 2007-09-07 Servier Lab Nouveaux composes 1,1-pyridinyloxycyclopropanamines polysusbstitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
TWI404532B (zh) 2006-11-02 2013-08-11 Targacept Inc 菸鹼乙醯膽鹼受體亞型選擇性之二氮雜雙環烷類醯胺

Also Published As

Publication number Publication date
EA020506B1 (ru) 2014-11-28
HK1175782A1 (en) 2013-07-12
EP2513085B1 (en) 2016-09-28
SMT201600444B (it) 2017-01-10
HUE033352T2 (en) 2017-11-28
AU2009355487B2 (en) 2013-10-10
CN102741239B (zh) 2015-06-24
SI2513085T1 (sl) 2017-02-28
JP5536227B2 (ja) 2014-07-02
EA201290344A1 (ru) 2012-10-30
MX2012005637A (es) 2012-06-13
ES2601905T3 (es) 2017-02-16
US8735423B2 (en) 2014-05-27
US20130072518A1 (en) 2013-03-21
ZA201203522B (en) 2013-01-31
IL219637A (en) 2015-10-29
PL2513085T3 (pl) 2017-09-29
WO2011061751A1 (en) 2011-05-26
EP2513085A1 (en) 2012-10-24
KR101376145B1 (ko) 2014-03-19
JP2013510901A (ja) 2013-03-28
RS55469B1 (sr) 2017-04-28
CY1118361T1 (el) 2017-06-28
KR20120049943A (ko) 2012-05-17
AU2009355487A1 (en) 2012-05-31
LT2513085T (lt) 2016-12-27
IL219637A0 (en) 2012-07-31
DK2513085T3 (en) 2016-12-05
HRP20161461T1 (hr) 2017-01-27
AU2009355487A8 (en) 2012-07-12
CA2773409C (en) 2015-06-16
NZ600536A (en) 2013-05-31
CA2773409A1 (en) 2011-05-26
CN102741239A (zh) 2012-10-17

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