PT2504331E - Composto, novas formas desse composto, composições farmacêuticas desse composto e métodos de preparação e utilização - Google Patents

Composto, novas formas desse composto, composições farmacêuticas desse composto e métodos de preparação e utilização Download PDF

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Publication number
PT2504331E
PT2504331E PT108311614T PT10831161T PT2504331E PT 2504331 E PT2504331 E PT 2504331E PT 108311614 T PT108311614 T PT 108311614T PT 10831161 T PT10831161 T PT 10831161T PT 2504331 E PT2504331 E PT 2504331E
Authority
PT
Portugal
Prior art keywords
compound
preparation
methods
pharmaceutical compositions
certain novel
Prior art date
Application number
PT108311614T
Other languages
English (en)
Original Assignee
Hutchison Medipharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44029398&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2504331(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hutchison Medipharma Ltd filed Critical Hutchison Medipharma Ltd
Publication of PT2504331E publication Critical patent/PT2504331E/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
PT108311614T 2009-11-23 2010-11-23 Composto, novas formas desse composto, composições farmacêuticas desse composto e métodos de preparação e utilização PT2504331E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2009101992592A CN102070618B (zh) 2009-11-23 2009-11-23 一种化合物及其晶体

Publications (1)

Publication Number Publication Date
PT2504331E true PT2504331E (pt) 2015-02-20

Family

ID=44029398

Family Applications (1)

Application Number Title Priority Date Filing Date
PT108311614T PT2504331E (pt) 2009-11-23 2010-11-23 Composto, novas formas desse composto, composições farmacêuticas desse composto e métodos de preparação e utilização

Country Status (18)

Country Link
US (2) US8658658B2 (pt)
EP (1) EP2504331B1 (pt)
JP (1) JP5758399B2 (pt)
KR (1) KR101513784B1 (pt)
CN (2) CN102070618B (pt)
AU (1) AU2010321366B2 (pt)
BR (1) BR112012012138B1 (pt)
CA (1) CA2781066C (pt)
DK (1) DK2504331T3 (pt)
ES (1) ES2529105T3 (pt)
IN (1) IN2012DN04868A (pt)
MX (1) MX2012005926A (pt)
MY (1) MY161749A (pt)
NZ (1) NZ600266A (pt)
PL (1) PL2504331T3 (pt)
PT (1) PT2504331E (pt)
RU (1) RU2507203C1 (pt)
WO (1) WO2011060746A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102070618B (zh) 2009-11-23 2013-08-21 和记黄埔医药（上海）有限公司 一种化合物及其晶体
MX2016016928A (es) * 2014-06-19 2017-04-25 Merial Inc Composiciones parasiticidas que comprenden derivados de indol, metodos y usos de los mismos.
CN105985326B (zh) * 2015-02-16 2020-04-14 上海宣创生物科技有限公司 嘧啶衍生物晶型ⅲ及其制备方法和用途
WO2016187767A1 (en) * 2015-05-25 2016-12-01 Hutchison Medipharma Limited Pharmaceutical compositions and use thereof
JP7308145B2 (ja) * 2016-11-18 2023-07-13 ハッチソン メディファーマ リミテッド 固形腫瘍を治療するための医薬組成物
JP2020164434A (ja) * 2019-03-28 2020-10-08 上野製薬株式会社 ２，６−ナフタレンビス（２−オキサゾリン）の製造方法
CN115052605A (zh) * 2020-03-09 2022-09-13 和记黄埔医药（上海）有限公司 抗pd-1抗体和多受体酪氨酸激酶抑制剂的药物组合及其使用方法
CN117136185A (zh) * 2021-04-12 2023-11-28 水疗免疫疗法有限公司 5-[（1,1-二氧化-4-硫代吗啉基）甲基]-2-苯基-n-（四氢-2h-吡喃-4-基）-1h-吲哚-7-胺的新晶型

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1976905A (zh) * 2004-03-30 2007-06-06 大正制药株式会社 嘧啶衍生物以及与其应用有关的治疗方法
EP1934200A1 (en) 2005-09-15 2008-06-25 Merck & Co., Inc. Tyrosine kinase inhibitors
WO2008128231A1 (en) 2007-04-16 2008-10-23 Hutchison Medipharma Enterprises Limited Pyrimidine derivatives
CN101289444B (zh) * 2007-04-16 2012-01-04 和记黄埔医药（上海）有限公司 一种嘧啶衍生物及其医药用途
TW201008933A (en) 2008-08-29 2010-03-01 Hutchison Medipharma Entpr Ltd Pyrimidine compounds
CN102070618B (zh) * 2009-11-23 2013-08-21 和记黄埔医药（上海）有限公司 一种化合物及其晶体

Also Published As

Publication number Publication date
KR101513784B1 (ko) 2015-04-20
AU2010321366A8 (en) 2012-07-05
CA2781066A1 (en) 2011-05-26
RU2507203C1 (ru) 2014-02-20
EP2504331B1 (en) 2014-11-12
WO2011060746A1 (en) 2011-05-26
CA2781066C (en) 2014-09-16
CN102070618A (zh) 2011-05-25
BR112012012138B1 (pt) 2023-02-07
NZ600266A (en) 2014-06-27
US20120270889A1 (en) 2012-10-25
CN102648194A (zh) 2012-08-22
EP2504331A1 (en) 2012-10-03
JP5758399B2 (ja) 2015-08-05
PL2504331T3 (pl) 2015-04-30
AU2010321366B2 (en) 2014-07-24
US20140200232A1 (en) 2014-07-17
RU2012126112A (ru) 2013-12-27
MY161749A (en) 2017-05-15
ES2529105T3 (es) 2015-02-16
BR112012012138A2 (pt) 2017-03-07
EP2504331A4 (en) 2013-04-17
JP2013511475A (ja) 2013-04-04
MX2012005926A (es) 2012-11-23
DK2504331T3 (en) 2014-12-08
IN2012DN04868A (pt) 2015-09-25
AU2010321366A1 (en) 2012-06-14
US8658658B2 (en) 2014-02-25
KR20120097526A (ko) 2012-09-04
CN102648194B (zh) 2014-10-29
US8946249B2 (en) 2015-02-03
CN102070618B (zh) 2013-08-21

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