PT1309672E - Processo de producao de reovirus infeccioso - Google Patents

Processo de producao de reovirus infeccioso

Info

Publication number
PT1309672E
PT1309672E PT01953084T PT01953084T PT1309672E PT 1309672 E PT1309672 E PT 1309672E PT 01953084 T PT01953084 T PT 01953084T PT 01953084 T PT01953084 T PT 01953084T PT 1309672 E PT1309672 E PT 1309672E
Authority
PT
Portugal
Prior art keywords
production process
infectious reovirus
reovirus production
infectious
reovirus
Prior art date
Application number
PT01953084T
Other languages
English (en)
Inventor
Matthew C Coffey
Bradley G Thompson
Original Assignee
Oncolytics Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncolytics Biotech Inc filed Critical Oncolytics Biotech Inc
Publication of PT1309672E publication Critical patent/PT1309672E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • A61K35/765Reovirus; Rotavirus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12051Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PT01953084T 2000-08-10 2001-07-20 Processo de producao de reovirus infeccioso PT1309672E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22402600P 2000-08-10 2000-08-10

Publications (1)

Publication Number Publication Date
PT1309672E true PT1309672E (pt) 2005-09-30

Family

ID=22838987

Family Applications (2)

Application Number Title Priority Date Filing Date
PT05009952T PT1586634E (pt) 2000-08-10 2001-07-20 Método de produzir reovírus infecciosos
PT01953084T PT1309672E (pt) 2000-08-10 2001-07-20 Processo de producao de reovirus infeccioso

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT05009952T PT1586634E (pt) 2000-08-10 2001-07-20 Método de produzir reovírus infecciosos

Country Status (19)

Country Link
US (4) US6528305B2 (pt)
EP (2) EP1586634B1 (pt)
JP (2) JP4009532B2 (pt)
AR (1) AR033993A1 (pt)
AT (2) ATE394475T1 (pt)
AU (2) AU7562801A (pt)
BR (1) BR0113122A (pt)
CA (1) CA2415749C (pt)
DE (2) DE60133947D1 (pt)
DK (2) DK1309672T3 (pt)
ES (2) ES2241844T3 (pt)
HK (1) HK1082765A1 (pt)
IL (2) IL153847A0 (pt)
MX (1) MXPA03000846A (pt)
NZ (1) NZ523510A (pt)
PT (2) PT1586634E (pt)
TW (1) TWI289158B (pt)
WO (1) WO2002012435A1 (pt)
ZA (1) ZA200300410B (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6545492B1 (en) * 1999-09-20 2003-04-08 Europaisches Laboratorium Fur Molekularbiologie (Embl) Multiple local probe measuring device and method
TWI289158B (en) * 2000-08-10 2007-11-01 Oncolytics Biotech Inc Method of producing infectious reovirus
BR0207527A (pt) * 2001-03-16 2004-02-25 Oncolytics Biotech Inc Método para produzir vìrus de uma cultura de células, composição, e, método para produzir reovìrus infeccioso
US20040115170A1 (en) * 2001-11-30 2004-06-17 Brown Earl Garnet Oncolytic virus
US20040005546A1 (en) 2002-02-28 2004-01-08 Oncolytics Biotech Inc. Use of ribozymes in the detection of adventitious agents
CA2374388C (en) 2002-02-28 2005-07-12 Matthew C. Coffey The use of ribozymes in the detection of adventitious agents
CA2426283C (en) * 2002-04-29 2006-06-27 The Trustees Of The University Of Pennsylvania Method for direct rescue and amplification of integrated viruses from cellular dna of tissues
AU2003229159B2 (en) 2002-04-30 2008-02-21 Oncolytics Biotech Inc. Improved viral purification methods
JP5241059B2 (ja) * 2002-05-09 2013-07-17 オンコリティクス バイオテク,インコーポレーテッド 腫瘍崩壊ウイルスを使用して疼痛を軽減するための方法
EP1944035A1 (en) 2002-05-09 2008-07-16 Oncolytics Biotech Inc. Method for reducing pain using oncolytic viruses
WO2003094939A1 (en) * 2002-05-10 2003-11-20 Oncolytics Biotech Inc. Sensitization of neoplastic cells to radiation therapy with oncolytic viruses
US7901921B2 (en) 2004-10-22 2011-03-08 Oncolytics Biotech Inc. Viral purification methods
US7490608B2 (en) * 2005-06-17 2009-02-17 Nellcorr Puritan Bennett Llc System and method for adjusting a gas delivery mask
WO2007099401A2 (en) 2005-08-01 2007-09-07 University Technologies International, Inc. Oncolytic attenuated reoviruses for treatment of proliferative disorders
US10668119B2 (en) 2005-08-01 2020-06-02 Virocure, Inc. Attenuated reovirus
AU2007215328A1 (en) * 2006-02-13 2007-08-23 Oncolytics Biotech Inc. Use of local immune suppression to enhance oncolytic viral therapy
US8293498B2 (en) 2006-12-20 2012-10-23 Vanderbilt University System for generation of viable reovirus from cloned cDNA
US20100322951A1 (en) * 2006-12-29 2010-12-23 Bacilligen, Inc. Replication-proficient dsRNA capsids and uses thereof
MX2009009598A (es) * 2007-03-12 2009-09-21 Oncolytics Biotech Inc Reovirus que tienen secuencias modificadas.
US10369171B2 (en) 2007-03-13 2019-08-06 Virocure, Inc. Attenuated reoviruses for selection of cell populations
AR066649A1 (es) * 2007-05-21 2009-09-02 Oncolytics Biotech Inc Reovirus mutantes y metodos de elaboracion y uso de los mismos
JP2011500608A (ja) * 2007-10-22 2011-01-06 オンコリティクス バイオテク,インコーポレーテッド 増殖性障害の治療レジメン
JP2011520994A (ja) * 2008-05-27 2011-07-21 オンコリティクス バイオテク,インコーポレーテッド 腫瘍崩解性レオウイルス療法中の炎症性サイトカイン産生の排除
TW200951143A (en) * 2008-05-27 2009-12-16 Oncolytics Biotech Inc Modulating interstitial pressure and oncolytic viral delivery and distribution
US9249195B2 (en) 2010-04-07 2016-02-02 Vanderbilt University Reovirus vaccines and methods of use therefor
JP2013523175A (ja) 2010-04-14 2013-06-17 イーエムディー・ミリポア・コーポレーション 高力価、高純度のウイルスストックの作製方法及びその使用方法
WO2012075379A2 (en) 2010-12-02 2012-06-07 Oncolytics Biotech Inc. Liquid viral formulations
AU2011336410B2 (en) 2010-12-02 2015-01-22 Oncolytics Biotech Inc. Lyophilized viral formulations
CA2930629A1 (en) 2013-11-15 2015-05-21 Oncolytics Biotech Inc. Oncolytic viruses and increased cancer treatment regimens

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070453A (en) * 1976-06-25 1978-01-24 Syntex (U.S.A.) Inc. Diploid porcine embryonic cell strains, cultures produced therefrom, and use of said cultures for production of vaccines
US4559229A (en) * 1982-07-20 1985-12-17 Research Foundation Avian proventriculitis vaccine
US5023252A (en) 1985-12-04 1991-06-11 Conrex Pharmaceutical Corporation Transdermal and trans-membrane delivery of drugs
JPS6344532A (ja) 1986-08-11 1988-02-25 Biseibutsu Kagaku Kenkyusho:Kk 豚のレオウイルス感染症ワクチン
US5658779A (en) 1992-03-20 1997-08-19 Ligochem, Inc. Method of adsorbing viruses from fluid compositions
JPH08214876A (ja) 1995-02-15 1996-08-27 Chemo Sero Therapeut Res Inst ウイルスの調製法
KR100503701B1 (ko) 1996-11-20 2005-07-26 인트로겐 테라페티스, 인코퍼레이티드 아데노바이러스 벡터를 생산하고 정제하는 개선된 방법
EP0993443A1 (de) 1997-06-24 2000-04-19 Basf Aktiengesellschaft Verfahren zur herstellung von 4,4'-dihalogendiphenylsulfon
US6110461A (en) * 1997-08-13 2000-08-29 Oncolytics Biotech Inc. Reovirus for the treatment of neoplasia
US6136307A (en) 1997-08-13 2000-10-24 Oncolytics Biotech Inc. Reovirus for the treatment of cellular proliferative disorders
AR028039A1 (es) 2000-05-03 2003-04-23 Oncolytics Biotech Inc Remocion de reovirus de celulas neoplasticas intermediadas por ras a partir de composiciones celulares mixtas
TWI289158B (en) * 2000-08-10 2007-11-01 Oncolytics Biotech Inc Method of producing infectious reovirus

Also Published As

Publication number Publication date
AU7562801A (en) 2002-02-18
IL153847A (en) 2007-10-31
US20020037576A1 (en) 2002-03-28
IL153847A0 (en) 2003-07-31
US6703232B2 (en) 2004-03-09
EP1309672B1 (en) 2005-06-29
ES2241844T3 (es) 2005-11-01
ZA200300410B (en) 2004-01-26
US20040126869A1 (en) 2004-07-01
BR0113122A (pt) 2003-07-22
JP2006314336A (ja) 2006-11-24
JP2004505623A (ja) 2004-02-26
ATE394475T1 (de) 2008-05-15
CA2415749C (en) 2009-05-12
HK1082765A1 (en) 2006-06-16
AR033993A1 (es) 2004-01-21
ES2305940T3 (es) 2008-11-01
JP4009532B2 (ja) 2007-11-14
PT1586634E (pt) 2008-06-19
WO2002012435A1 (en) 2002-02-14
DE60133947D1 (de) 2008-06-19
NZ523510A (en) 2004-08-27
TWI289158B (en) 2007-11-01
ATE298788T1 (de) 2005-07-15
MXPA03000846A (es) 2004-04-05
US20060165724A1 (en) 2006-07-27
US20030166253A1 (en) 2003-09-04
CA2415749A1 (en) 2002-02-14
EP1586634B1 (en) 2008-05-07
AU2001275628B8 (en) 2002-02-18
US6528305B2 (en) 2003-03-04
US7049127B2 (en) 2006-05-23
DK1586634T3 (da) 2008-08-18
AU2001275628B2 (en) 2007-08-30
DE60111747T2 (de) 2006-04-27
DE60111747D1 (de) 2005-08-04
EP1309672A1 (en) 2003-05-14
DK1309672T3 (da) 2005-10-10
EP1586634A1 (en) 2005-10-19
US7429485B2 (en) 2008-09-30

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