DK1309672T3 - Fremgangsmåde til fremstilling af infektiös reovirus - Google Patents

Fremgangsmåde til fremstilling af infektiös reovirus

Info

Publication number
DK1309672T3
DK1309672T3 DK01953084T DK01953084T DK1309672T3 DK 1309672 T3 DK1309672 T3 DK 1309672T3 DK 01953084 T DK01953084 T DK 01953084T DK 01953084 T DK01953084 T DK 01953084T DK 1309672 T3 DK1309672 T3 DK 1309672T3
Authority
DK
Denmark
Prior art keywords
producing infectious
infectious reovirus
reovirus
producing
infectious
Prior art date
Application number
DK01953084T
Other languages
Danish (da)
English (en)
Inventor
Matthew C Coffey
Bradley G Thompson
Original Assignee
Oncolytics Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncolytics Biotech Inc filed Critical Oncolytics Biotech Inc
Application granted granted Critical
Publication of DK1309672T3 publication Critical patent/DK1309672T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • A61K35/765Reovirus; Rotavirus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12051Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK01953084T 2000-08-10 2001-07-20 Fremgangsmåde til fremstilling af infektiös reovirus DK1309672T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22402600P 2000-08-10 2000-08-10
PCT/CA2001/001054 WO2002012435A1 (en) 2000-08-10 2001-07-20 Method of producing infectious reovirus

Publications (1)

Publication Number Publication Date
DK1309672T3 true DK1309672T3 (da) 2005-10-10

Family

ID=22838987

Family Applications (2)

Application Number Title Priority Date Filing Date
DK05009952T DK1586634T3 (da) 2000-08-10 2001-07-20 Fremgangsmåde til fremstilling af infektiös reovirus
DK01953084T DK1309672T3 (da) 2000-08-10 2001-07-20 Fremgangsmåde til fremstilling af infektiös reovirus

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK05009952T DK1586634T3 (da) 2000-08-10 2001-07-20 Fremgangsmåde til fremstilling af infektiös reovirus

Country Status (19)

Country Link
US (4) US6528305B2 (pt)
EP (2) EP1586634B1 (pt)
JP (2) JP4009532B2 (pt)
AR (1) AR033993A1 (pt)
AT (2) ATE394475T1 (pt)
AU (2) AU7562801A (pt)
BR (1) BR0113122A (pt)
CA (1) CA2415749C (pt)
DE (2) DE60111747T2 (pt)
DK (2) DK1586634T3 (pt)
ES (2) ES2305940T3 (pt)
HK (1) HK1082765A1 (pt)
IL (2) IL153847A0 (pt)
MX (1) MXPA03000846A (pt)
NZ (1) NZ523510A (pt)
PT (2) PT1309672E (pt)
TW (1) TWI289158B (pt)
WO (1) WO2002012435A1 (pt)
ZA (1) ZA200300410B (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6545492B1 (en) * 1999-09-20 2003-04-08 Europaisches Laboratorium Fur Molekularbiologie (Embl) Multiple local probe measuring device and method
TWI289158B (en) * 2000-08-10 2007-11-01 Oncolytics Biotech Inc Method of producing infectious reovirus
CA2437962C (en) * 2001-03-16 2005-11-15 Oncolytics Biotech Inc. Method of extracting virus from cell culture
US20040115170A1 (en) * 2001-11-30 2004-06-17 Brown Earl Garnet Oncolytic virus
CA2374388C (en) * 2002-02-28 2005-07-12 Matthew C. Coffey The use of ribozymes in the detection of adventitious agents
US20040005546A1 (en) 2002-02-28 2004-01-08 Oncolytics Biotech Inc. Use of ribozymes in the detection of adventitious agents
WO2003093460A1 (en) * 2002-04-29 2003-11-13 The Trustees Of The University Of Pennsylvania Method for direct rescue and amplification of integrated viruses from cellular dna of tissues
WO2003093463A1 (en) * 2002-04-30 2003-11-13 Oncolytics Biotech Inc. Improved viral purification methods
MXPA04011007A (es) * 2002-05-09 2005-02-14 Oncolytics Biotech Inc Metodo para reducir el dolor usando virus oncoliticos.
EP1944035A1 (en) 2002-05-09 2008-07-16 Oncolytics Biotech Inc. Method for reducing pain using oncolytic viruses
JP4546823B2 (ja) * 2002-05-10 2010-09-22 オンコリティクス バイオテク,インコーポレーテッド 腫瘍崩壊性ウイルスによる放射線療法に対する新生物細胞の感作
US7901921B2 (en) 2004-10-22 2011-03-08 Oncolytics Biotech Inc. Viral purification methods
US7490608B2 (en) * 2005-06-17 2009-02-17 Nellcorr Puritan Bennett Llc System and method for adjusting a gas delivery mask
US10668119B2 (en) 2005-08-01 2020-06-02 Virocure, Inc. Attenuated reovirus
US10260049B2 (en) 2005-08-01 2019-04-16 Virocure, Inc. Attenuated reovirus
JP2009525989A (ja) * 2006-02-13 2009-07-16 オンコリティクス バイオテク,インコーポレーテッド 腫瘍溶解性ウイルスの治療を増強させる局所的免疫抑制の使用
US8293498B2 (en) 2006-12-20 2012-10-23 Vanderbilt University System for generation of viable reovirus from cloned cDNA
WO2008127486A2 (en) * 2006-12-29 2008-10-23 Bacilligen, Inc. Replication-proficient dsrna capsids and uses thereof
EP2132315B1 (en) 2007-03-12 2015-07-15 Oncolytics Biotech Inc. Reoviruses having modified sequences
US10369171B2 (en) 2007-03-13 2019-08-06 Virocure, Inc. Attenuated reoviruses for selection of cell populations
TW200909581A (en) * 2007-05-21 2009-03-01 Oncolytics Biotech Inc Mutant reoviruses and methods of making and using
AU2008316276A1 (en) * 2007-10-22 2009-04-30 Oncolytics Biotech Inc. Treatment regime for proliferative disorders
US20110086005A1 (en) * 2008-05-27 2011-04-14 Oncolytics Biotech Inc. Modulating interstitial pressure and oncolytic viral delivery and distribution
EP2296679A4 (en) * 2008-05-27 2012-03-21 Oncolytics Biotech Inc SUPPRESSION OF PRODUCTION OF PRO-INFLAMMATORY CYTOKINES DURING ONCOLYTIC REOVIRUS THERAPY
WO2011126976A1 (en) 2010-04-07 2011-10-13 Vanderbilt University Reovirus vaccines and methods of use therefor
CN102985536B (zh) 2010-04-14 2017-12-05 Emd密理博公司 生产高效价、高纯度的病毒母液的方法及使用其的方法
TW201233803A (en) 2010-12-02 2012-08-16 Oncolytics Biotech Inc Lyophilized viral formulations
JP6034798B2 (ja) 2010-12-02 2016-11-30 オンコリティクス バイオテク,インコーポレーテッド 液体ウイルス製剤
ES2796950T3 (es) 2013-11-15 2020-11-30 Oncolytics Biotech Inc Virus oncolíticos y regímenes reforzados para tratamiento de cáncer

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070453A (en) * 1976-06-25 1978-01-24 Syntex (U.S.A.) Inc. Diploid porcine embryonic cell strains, cultures produced therefrom, and use of said cultures for production of vaccines
US4559229A (en) * 1982-07-20 1985-12-17 Research Foundation Avian proventriculitis vaccine
US5023252A (en) 1985-12-04 1991-06-11 Conrex Pharmaceutical Corporation Transdermal and trans-membrane delivery of drugs
JPS6344532A (ja) 1986-08-11 1988-02-25 Biseibutsu Kagaku Kenkyusho:Kk 豚のレオウイルス感染症ワクチン
US5658779A (en) 1992-03-20 1997-08-19 Ligochem, Inc. Method of adsorbing viruses from fluid compositions
JPH08214876A (ja) 1995-02-15 1996-08-27 Chemo Sero Therapeut Res Inst ウイルスの調製法
WO1998022588A2 (en) 1996-11-20 1998-05-28 Introgen Therapeutics, Inc. An improved method for the production and purification of adenoviral vectors
EP0993443A1 (de) 1997-06-24 2000-04-19 Basf Aktiengesellschaft Verfahren zur herstellung von 4,4'-dihalogendiphenylsulfon
US6136307A (en) * 1997-08-13 2000-10-24 Oncolytics Biotech Inc. Reovirus for the treatment of cellular proliferative disorders
US6110461A (en) * 1997-08-13 2000-08-29 Oncolytics Biotech Inc. Reovirus for the treatment of neoplasia
AR028039A1 (es) 2000-05-03 2003-04-23 Oncolytics Biotech Inc Remocion de reovirus de celulas neoplasticas intermediadas por ras a partir de composiciones celulares mixtas
TWI289158B (en) * 2000-08-10 2007-11-01 Oncolytics Biotech Inc Method of producing infectious reovirus

Also Published As

Publication number Publication date
DE60133947D1 (de) 2008-06-19
EP1309672A1 (en) 2003-05-14
TWI289158B (en) 2007-11-01
ATE298788T1 (de) 2005-07-15
US7429485B2 (en) 2008-09-30
US20030166253A1 (en) 2003-09-04
AU2001275628B2 (en) 2007-08-30
PT1586634E (pt) 2008-06-19
AU7562801A (en) 2002-02-18
BR0113122A (pt) 2003-07-22
US20040126869A1 (en) 2004-07-01
DE60111747D1 (de) 2005-08-04
EP1586634A1 (en) 2005-10-19
PT1309672E (pt) 2005-09-30
JP2004505623A (ja) 2004-02-26
ES2305940T3 (es) 2008-11-01
US20060165724A1 (en) 2006-07-27
AR033993A1 (es) 2004-01-21
US6703232B2 (en) 2004-03-09
US6528305B2 (en) 2003-03-04
EP1309672B1 (en) 2005-06-29
CA2415749A1 (en) 2002-02-14
US20020037576A1 (en) 2002-03-28
HK1082765A1 (en) 2006-06-16
US7049127B2 (en) 2006-05-23
WO2002012435A1 (en) 2002-02-14
DK1586634T3 (da) 2008-08-18
NZ523510A (en) 2004-08-27
JP4009532B2 (ja) 2007-11-14
IL153847A (en) 2007-10-31
DE60111747T2 (de) 2006-04-27
AU2001275628B8 (en) 2002-02-18
EP1586634B1 (en) 2008-05-07
ES2241844T3 (es) 2005-11-01
JP2006314336A (ja) 2006-11-24
ZA200300410B (en) 2004-01-26
MXPA03000846A (es) 2004-04-05
ATE394475T1 (de) 2008-05-15
CA2415749C (en) 2009-05-12
IL153847A0 (en) 2003-07-31

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